Monocytes are target cells for IL-10 induction by HIV-1 Nef protein

Cytokine

Volumn 12, Issue 10, 2000, Pages 1506-1511

  Tangsinmankong, Nutthapong ^a   Day, Noorbibi K ^a   Good, Robert A ^a   Haraguchi, Soichi ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

HIV 1 Nef; IL 10; Monocytes

Indexed keywords

CALMODULIN INHIBITOR; CYTOKINE; INTERLEUKIN 10; MESSENGER RNA; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; NEF PROTEIN; VIRUS PROTEIN;

ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; VIRUS INFECTION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0033790254     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2000.0741     Document Type: Article

References (39)

1. Immunosuppressive retroviral peptides: Immunopathological implications for immunosuppressive influences of retroviral infections
2. Immunosuppressive retroviral peptides: cAMP and cytokine patterns
3. Demonstration of the Th1 to Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by flow cytometry
4. The Th1-Th2 hypothesis of HIV infection: New insights
5. Th1 and Th2 cytokine production by peripheral blood mononuclear cells from HIV-infected patients
6. Type 1 cytokine production and low prevalence of viral isolation correlate with long-term nonprogression in HIV infection
7. Human immunodeficiency virus (HIV) phenotype and interleukin-2/ interleukin-10 ratio are associated markers of protection and progression in HIV infection
8. Differential production of interleukin 10 during human immunodeficiency virus infection
9. IL-10 cooperates with TNF-alpha to activate HIV-1 from latently and acutely infected cells of monocyte/macrophage lineage
10. Interleukin-10 enhances human immunodeficiency virus type I expression in a chronically infected promonocytic cell line (UI) by a tumor necrosis factor alpha-independent mechanism
11. Importance of the nef gene for maintenance of high virus loads and for development of AIDS
12. Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
13. Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
14. Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
15. HIV accessory proteins: Leading roles for the supporting cast
16. Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis
17. The human immunodeficiency virus-1 nef gene product: A positive factor for viral infection and replication in primary lymphocytes and macrophages
18. The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes
19. Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene
20. Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway
21. Interleukin-10: Biology, role in inflammation and autoimmunity
22. IL-10: A potential therapy for allergic inflammation?
23. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production
24. IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells
25. IL-10, T lymphocyte inhibitor of human blood cell production of IL-1 and tumor necrosis factor
26. IL-10 inhibits cytokine production by activated macrophages
27. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
28. gp41 Envelope protein of human immunodeficiency virus induces interleukin (IL)-10 in monocytes, but not in B, T, or NK cells, leading to reduced IL-2 and interferon-gamma production
29. HIV-1 recombinant gp41 induces IL-10 expression and production in peripheral blood monocytes but not in T-lymphocytes
30. Human immunodeficiency virus gp120 inhibits interleukin-12 secretion by human monocytes: An indirect interleukin-10-mediated effect
31. Differential production of IL-10 by T cells and monocytes of HIV-infected individuals: Association of IL-10 production with CD28-mediated immune responsiveness
32. CD8+ cells are the main producers of IL10 and IFN gamma after superantigen stimulation
33. Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivo
34. Induction of type 2 cytokines by a staphylococcal enterotoxin superantigen
35. Sequential production of IL-2, IFN-γ and IL-10 by individual staphylococcal enterotoxin B-activated T helper lymphocytes
36. Direct activation of murine T cells by staphylococcal enterotoxins
37. Production of TNF-α and TNF-β by staphylococcal enterotoxin A activated human T cells
38. Induction of interleukin-1 in human monocytes by the superantigen staphylococcal enterotoxin A requires the participation of T cells
39. Identification of an HIV-1 Nef peptide that binds to HLA class II antigens