Computational studies of the farnesyltransferase ternary complex part I: Substrate binding

Biochemistry

Volumn 44, Issue 50, 2005, Pages 16513-16523

  Cui, Guanglei ^a   Wang, Bing ^a   Merz Jr , Kenneth M ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CELL MEMBRANES; REACTION KINETICS; SIGNAL PROCESSING; TERNARY SYSTEMS; TUMORS;

FARNESYLTRANSFERASE (FTASE); PROTEIN ACCEPTORS; SUBSTRATE BINDING;

ENZYMES;

CYSTEINE; FARNESYL DIPHOSPHATE; FARNESYLTRANSFERASE; PROTEIN; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; TETRAPEPTIDE; TRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CALCULATION; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME INHIBITOR INTERACTION; ENZYME SUBSTRATE COMPLEX; MOLECULAR DYNAMICS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SIMULATION;

FARNESYLTRANSTRANSFERASE; HYDROGEN BONDING; MODELS, MOLECULAR; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 29344458799     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051020m     Document Type: Article

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