Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate

Biochemistry

Volumn 37, Issue 27, 1998, Pages 9612-9618

  Long, Stephen B ^a   Casey, Patrick J ^a   Beese, Lorena S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CYSTEINE; ISOPRENOID; PROTEIN FARNESYLTRANSFERASE; PYROPHOSPHATE; RAS PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; RAT;

ALKYL AND ARYL TRANSFERASES; ANIMALS; BINDING SITES; COMPUTER SIMULATION; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; POLYISOPRENYL PHOSPHATES; PROTEIN BINDING; PROTEIN ISOPRENYLATION; RATS; SUBSTRATE SPECIFICITY;

EID: 0032493317     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980708e     Document Type: Article

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