The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic

Biochemical Journal

Volumn 330, Issue 3, 1998, Pages 1451-1460

  Tombes, Robert M ^a   Auer, Kelly L ^a   Mikkelsen, Ross ^a   Valerie, Kristopher ^a   Wymann, Mathias P ^b   Marshall, Christopher J ^c   McMahon, Martin ^d   Dent, Paul ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FRIBOURG   (Switzerland)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CELL DNA; CYCLIN DEPENDENT KINASE; ESTROGEN RECEPTOR; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; PROTEIN KINASE INHIBITOR; PROTEIN P16; PROTEIN P21; RAF PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA SYNTHESIS; DNA SYNTHESIS INHIBITION; ENZYME ACTIVATION; ENZYME ACTIVITY; LIVER CELL; MALE; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0032521642     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3301451     Document Type: Article

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