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Volumn 37, Issue 8, 2005, Pages 590-602

Serotonin gene polymorphisms and bipolar I disorder: Focus on the serotonin transporter

(29)  Mansour, Hader A a   Talkowski, Michael E a   Wood, Joel a   Pless, Lora a   Bamne, Mikhil a   Chowdari, Kodavali V a   Allen, Michael b   Bowden, Charles L c   Calabrese, Joseph d   El Mallakh, Rif S e   Fagiolini, Andrea a   Faraone, Stephen V f   Fossey, Mark D g   Friedman, Edward S a   Gyulai, Laszlo h   Hauser, Peter i,j   Ketter, Terence A k   Loftis, Jennifer M i,j   Marangell, Lauren B l   Miklowitz, David J m   more..


Author keywords

Association; Bipolar disorder; Genetic; Polymorphism; Serotonin; Serotonin transporter

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); SEROTONIN; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER; TRYPTOPHAN HYDROXYLASE;

EID: 28844469295     PISSN: 07853890     EISSN: 16512219     Source Type: Journal    
DOI: 10.1080/07853890500357428     Document Type: Review
Times cited : (40)

References (108)
  • 1
    • 0025030265 scopus 로고
    • Genetic mapping of common diseases: The challenges of manic-depressive illness and schizophrenia
    • Gershon ES, Martinez M, Goldin LR, Gejman PV. Genetic mapping of common diseases: the challenges of manic-depressive illness and schizophrenia. Trends Genet. 1990;6:282-7.
    • (1990) Trends Genet , vol.6 , pp. 282-287
    • Gershon, E.S.1    Martinez, M.2    Goldin, L.R.3    Gejman, P.V.4
  • 2
    • 0032803524 scopus 로고    scopus 로고
    • Genetics of bipolar disorder
    • Craddock N, Jones I. Genetics of bipolar disorder. J Med Genet. 1999;36:585-94.
    • (1999) J Med Genet , vol.36 , pp. 585-594
    • Craddock, N.1    Jones, I.2
  • 3
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science. 1996;273:1516-7.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 4
    • 0034723057 scopus 로고    scopus 로고
    • Pharmacogenetics and the serotonin system: Initial studies and future directions
    • Veenstra-VanderWeele J, Anderson GM, Cook EH, Jr. Pharmacogenetics and the serotonin system: initial studies and future directions. Eur J Pharmacol. 2000;410:165-81.
    • (2000) Eur J Pharmacol , vol.410 , pp. 165-181
    • Veenstra-VanderWeele, J.1    Anderson, G.M.2    Cook Jr., E.H.3
  • 5
    • 0032145922 scopus 로고    scopus 로고
    • Genetically driven variation in serotonin uptake: Is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?
    • Lesch KP, Mossner R. Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders? Biol Psychiatry. 1998;44:179-92.
    • (1998) Biol Psychiatry , vol.44 , pp. 179-192
    • Lesch, K.P.1    Mossner, R.2
  • 6
    • 0028265462 scopus 로고
    • Role of serotonin in the pathophysiology of depression: Focus on the serotonin transporter
    • Owens MJ, Nemeroff CB. Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clin Chem. 1994;40:288-95.
    • (1994) Clin Chem , vol.40 , pp. 288-295
    • Owens, M.J.1    Nemeroff, C.B.2
  • 7
    • 0034655423 scopus 로고    scopus 로고
    • Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety
    • Sibille E, Pavlides C, Benke D, Toth M. Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety. J Neurosci. 2000;20:2758-65.
    • (2000) J Neurosci , vol.20 , pp. 2758-2765
    • Sibille, E.1    Pavlides, C.2    Benke, D.3    Toth, M.4
  • 8
    • 0035073901 scopus 로고    scopus 로고
    • Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice
    • Berl.
    • Gingrich JA, Hen R. Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice. Psychopharmacology (Berl). 2001;155:1-10.
    • (2001) Psychopharmacology , vol.155 , pp. 1-10
    • Gingrich, J.A.1    Hen, R.2
  • 9
    • 0345305851 scopus 로고    scopus 로고
    • Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders
    • Murphy DL, Uhl GR, Holmes A, Ren-Patterson R, Hall FS, Sora I, et al. Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders. Genes Brain Behav. 2003;2:350-64.
    • (2003) Genes Brain Behav , vol.2 , pp. 350-364
    • Murphy, D.L.1    Uhl, G.R.2    Holmes, A.3    Ren-Patterson, R.4    Hall, F.S.5    Sora, I.6
  • 10
    • 0742305531 scopus 로고    scopus 로고
    • Age-dependent antidepressant pharmacogenomics: Polymorphisms of the serotonin transporter and G protein beta3 subunit as predictors of response to fluoxetine and nortriptyline
    • Joyce PR, Mulder RT, Luty SE, McKenzie JM, Miller AL, Rogers GR, et al. Age-dependent antidepressant pharmacogenomics: polymorphisms of the serotonin transporter and G protein beta3 subunit as predictors of response to fluoxetine and nortriptyline. Int J Neuropsychopharmacology. 2003;6:339-46.
    • (2003) Int J Neuropsychopharmacology , vol.6 , pp. 339-346
    • Joyce, P.R.1    Mulder, R.T.2    Luty, S.E.3    McKenzie, J.M.4    Miller, A.L.5    Rogers, G.R.6
  • 12
    • 4344696091 scopus 로고    scopus 로고
    • Implications of genetic research on the role of the serotonin in depression: Emphasis on the serotonin type 1A receptor and the serotonin transporter
    • Berl. Epub. 2004 Jul 13
    • Neumeister A, Young T, Stastny J. Implications of genetic research on the role of the serotonin in depression: emphasis on the serotonin type 1A receptor and the serotonin transporter. Psychopharmacology (Berl). 2004;174:512-24. Epub. 2004 Jul 13.
    • (2004) Psychopharmacology , vol.174 , pp. 512-524
    • Neumeister, A.1    Young, T.2    Stastny, J.3
  • 14
    • 0025734886 scopus 로고
    • Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3-p14 by in situ hybridization
    • Craig SP, Boularand S, Darmon MC, Mallet J, Craig IW. Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3-p14 by in situ hybridization. Cytogenet Cell Genet. 1991;56:157-9.
    • (1991) Cytogenet Cell Genet , vol.56 , pp. 157-159
    • Craig, S.P.1    Boularand, S.2    Darmon, M.C.3    Mallet, J.4    Craig, I.W.5
  • 19
    • 0034640692 scopus 로고    scopus 로고
    • Association study of the tryptophan hydroxylase gene and bipolar affective disorder using family-based internal controls
    • Rietschel M, Schorr A, Albus M, Franzek E, Kreiner R, Held T, et al. Association study of the tryptophan hydroxylase gene and bipolar affective disorder using family-based internal controls. Am J Med Genet. 2000;96:310-1.
    • (2000) Am J Med Genet , vol.96 , pp. 310-311
    • Rietschel, M.1    Schorr, A.2    Albus, M.3    Franzek, E.4    Kreiner, R.5    Held, T.6
  • 20
    • 0032496310 scopus 로고    scopus 로고
    • No association of the tryptophan hydroxylase gene with bipolar affective disorder, unipolar affective disorder, or suicidal behaviour in major affective disorder
    • Furlong RA, Ho L, Rubinsztein JS, Walsh C, Paykel ES, Rubinsztein DC. No association of the tryptophan hydroxylase gene with bipolar affective disorder, unipolar affective disorder, or suicidal behaviour in major affective disorder. Am J Med Genet. 1998;81:245-7.
    • (1998) Am J Med Genet , vol.81 , pp. 245-247
    • Furlong, R.A.1    Ho, L.2    Rubinsztein, J.S.3    Walsh, C.4    Paykel, E.S.5    Rubinsztein, D.C.6
  • 21
    • 0037042105 scopus 로고    scopus 로고
    • Family-based association study of 5-HTTLPR, TPH, MAO-A, and DRD4 polymorphisms in mood disorders
    • Serretti A, Cristina S, Lilli R, Cusin C, Lattuada E, Lorenzi C, et al. Family-based association study of 5-HTTLPR, TPH, MAO-A, and DRD4 polymorphisms in mood disorders. Am J Med Genet. 2002;114:361-9.
    • (2002) Am J Med Genet , vol.114 , pp. 361-369
    • Serretti, A.1    Cristina, S.2    Lilli, R.3    Cusin, C.4    Lattuada, E.5    Lorenzi, C.6
  • 23
    • 11344282078 scopus 로고    scopus 로고
    • Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Analysis of the novel TPH2 gene in bipolar disorder and suicidality
    • Zhang X, Gainetdinov RR, Beaulieu JM, Sotnikova TD, Burch LH, Williams RB, et al. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Analysis of the novel TPH2 gene in bipolar disorder and suicidality. Neuron. 2005;45:11-6.
    • (2005) Neuron , vol.45 , pp. 11-16
    • Zhang, X.1    Gainetdinov, R.R.2    Beaulieu, J.M.3    Sotnikova, T.D.4    Burch, L.H.5    Williams, R.B.6
  • 25
    • 0036570263 scopus 로고    scopus 로고
    • Association of 5-HT(2A) receptor gene polymorphism with major affective disorders: The case of a subgroup of bipolar disorder with low suicide risk
    • Bonnier B, Gorwood P, Hamon M, Sarfati Y, Boni C, Hardy-Bayle MC. Association of 5-HT(2A) receptor gene polymorphism with major affective disorders: the case of a subgroup of bipolar disorder with low suicide risk. Biol Psychiatry. 2002;51:762-5.
    • (2002) Biol Psychiatry , vol.51 , pp. 762-765
    • Bonnier, B.1    Gorwood, P.2    Hamon, M.3    Sarfati, Y.4    Boni, C.5    Hardy-Bayle, M.C.6
  • 27
    • 0031010498 scopus 로고    scopus 로고
    • No association between bipolar affective disorder and a serotonin receptor (5-HT2A) polymorphism
    • Mahieu B, Souery D, Lipp O, Mendelbaum K, Verheyen G, De Maertelaer V, et al. No association between bipolar affective disorder and a serotonin receptor (5-HT2A) polymorphism. Psychiatry Res. 1997;70:65-9.
    • (1997) Psychiatry Res , vol.70 , pp. 65-69
    • Mahieu, B.1    Souery, D.2    Lipp, O.3    Mendelbaum, K.4    Verheyen, G.5    De Maertelaer, V.6
  • 29
    • 0034600074 scopus 로고    scopus 로고
    • A European multicenter association study of HTR2A receptor polymorphism in bipolar affective disorder
    • Massat I, Souery D, Lipp O, Blairy S, Papadimitriou G, Dikeos D, et al. A European multicenter association study of HTR2A receptor polymorphism in bipolar affective disorder. Am J Med Genet. 2000;96:136-40.
    • (2000) Am J Med Genet , vol.96 , pp. 136-140
    • Massat, I.1    Souery, D.2    Lipp, O.3    Blairy, S.4    Papadimitriou, G.5    Dikeos, D.6
  • 30
    • 0034097644 scopus 로고    scopus 로고
    • Negative association between T102C polymorphism at the 5-HT2A receptor gene and bipolar affective disorders in Singaporean Chinese
    • Tut TG, Wang JL, Lim CC. Negative association between T102C polymorphism at the 5-HT2A receptor gene and bipolar affective disorders in Singaporean Chinese. J Affect Disord. 2000;58:211-4.
    • (2000) J Affect Disord , vol.58 , pp. 211-214
    • Tut, T.G.1    Wang, J.L.2    Lim, C.C.3
  • 31
    • 0033583436 scopus 로고    scopus 로고
    • Serotonin transporter gene not associated with psychotic symptomatology of mood disorders
    • Serretti A, Lattuada E, Catalano M, Smeraldi E. Serotonin transporter gene not associated with psychotic symptomatology of mood disorders. Psychiatry Res. 1999;86:59-65.
    • (1999) Psychiatry Res , vol.86 , pp. 59-65
    • Serretti, A.1    Lattuada, E.2    Catalano, M.3    Smeraldi, E.4
  • 34
    • 0041318992 scopus 로고    scopus 로고
    • Linkage and association between serotonin 2A receptor gene polymorphisms and bipolar I disorder
    • Ranade SS, Mansour H, Wood J, Chowdari KV, Brar LK, Kupfer DJ, et al. Linkage and association between serotonin 2A receptor gene polymorphisms and bipolar I disorder. Am J Med Genet. 2003;121B:28-34.
    • (2003) Am J Med Genet , vol.121 , pp. 28-34
    • Ranade, S.S.1    Mansour, H.2    Wood, J.3    Chowdari, K.V.4    Brar, L.K.5    Kupfer, D.J.6
  • 35
    • 0029075560 scopus 로고
    • The transmission/disequilibrium test: History, subdivision, and admixture
    • Ewens WJ, Spielman RS. The transmission/disequilibrium test: history, subdivision, and admixture. Am J Hum Genet. 1995;57:455-64.
    • (1995) Am J Hum Genet , vol.57 , pp. 455-464
    • Ewens, W.J.1    Spielman, R.S.2
  • 36
    • 0027033392 scopus 로고
    • Serotonin receptor Ic gene assigned to X chromosome in human (band q24) and mouse (bands D-F4)
    • Milatovich A, Hsieh CL, Bonaminio G, Tecott L, Julius D, Francke U. Serotonin receptor Ic gene assigned to X chromosome in human (band q24) and mouse (bands D-F4). Hum Mol Genet. 1992;1:681-4.
    • (1992) Hum Mol Genet , vol.1 , pp. 681-684
    • Milatovich, A.1    Hsieh, C.L.2    Bonaminio, G.3    Tecott, L.4    Julius, D.5    Francke, U.6
  • 37
    • 0033817761 scopus 로고    scopus 로고
    • A review of the role of serotonin receptors in psychiatric disorders
    • Naughton M, Mulrooney JB, Leonard BE. A review of the role of serotonin receptors in psychiatric disorders. Hum Psychopharmacol. 2000;15:397-415.
    • (2000) Hum Psychopharmacol , vol.15 , pp. 397-415
    • Naughton, M.1    Mulrooney, J.B.2    Leonard, B.E.3
  • 38
  • 39
    • 0030842646 scopus 로고    scopus 로고
    • Association analysis of the 5-HT2C receptor and 5-HT transporter genes in bipolar disorder
    • Oruc L, Verheyen GR, Furac I, Jakovljevic M, Ivezic S, Raeymaekers P, et al. Association analysis of the 5-HT2C receptor and 5-HT transporter genes in bipolar disorder. Am J Med Genet. 1997;74(5):504-6.
    • (1997) Am J Med Genet , vol.74 , Issue.5 , pp. 504-506
    • Oruc, L.1    Verheyen, G.R.2    Furac, I.3    Jakovljevic, M.4    Ivezic, S.5    Raeymaekers, P.6
  • 40
    • 0035943536 scopus 로고    scopus 로고
    • Association study between novel promoter variants at the 5-HT2C receptor gene and human patients with bipolar affective disorder
    • Gutierrez B, Arias B, Papiol S, Rosa A, Fananas L. Association study between novel promoter variants at the 5-HT2C receptor gene and human patients with bipolar affective disorder. Neurosci Lett. 2001;309:135-7.
    • (2001) Neurosci Lett , vol.309 , pp. 135-137
    • Gutierrez, B.1    Arias, B.2    Papiol, S.3    Rosa, A.4    Fananas, L.5
  • 41
    • 0036328051 scopus 로고    scopus 로고
    • Evolutionary conserved microsatellites in the promoter region of the 5-hydroxytryptamine receptor 2C gene (HTR2C) are not associated with bipolar disorder in females
    • Meyer J, Saam W, Mossner R, Cangir O, Ortega GR, Tatschner T, et al. Evolutionary conserved microsatellites in the promoter region of the 5-hydroxytryptamine receptor 2C gene (HTR2C) are not associated with bipolar disorder in females. J Neural Transm. 2002;109:939-46.
    • (2002) J Neural Transm , vol.109 , pp. 939-946
    • Meyer, J.1    Saam, W.2    Mossner, R.3    Cangir, O.4    Ortega, G.R.5    Tatschner, T.6
  • 42
    • 17944371747 scopus 로고    scopus 로고
    • Variability of 5-HT2C receptor cys23ser polymorphism among European populations and vulnerability to affective disorder
    • Lerer B, Macciardi F, Segman RH, Adolfsson R, Blackwood D, Blairy S, et al. Variability of 5-HT2C receptor cys23ser polymorphism among European populations and vulnerability to affective disorder. Mol Psychiatry. 2001;6:579-85.
    • (2001) Mol Psychiatry , vol.6 , pp. 579-585
    • Lerer, B.1    Macciardi, F.2    Segman, R.H.3    Adolfsson, R.4    Blackwood, D.5    Blairy, S.6
  • 43
    • 0034599554 scopus 로고    scopus 로고
    • Serotonin-2C and serotonin-1A receptor genes are not associated with psychotic symptomatology of mood disorders
    • Serretti A, Lilli R, Lorenzi C, Lattuada E, Smeraldi E. Serotonin-2C and serotonin-1A receptor genes are not associated with psychotic symptomatology of mood disorders. Am J Med Genet. 2000;96:161-6.
    • (2000) Am J Med Genet , vol.96 , pp. 161-166
    • Serretti, A.1    Lilli, R.2    Lorenzi, C.3    Lattuada, E.4    Smeraldi, E.5
  • 44
    • 0034742439 scopus 로고    scopus 로고
    • Association between the 5′ UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder
    • Niesler B, Flohr T, Nothen MM, Fischer C, Rietschel M, Franzek E, et al. Association between the 5′ UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder. Pharmacogenetics. 2001;11:471-5.
    • (2001) Pharmacogenetics , vol.11 , pp. 471-475
    • Niesler, B.1    Flohr, T.2    Nothen, M.M.3    Fischer, C.4    Rietschel, M.5    Franzek, E.6
  • 45
    • 0036430342 scopus 로고    scopus 로고
    • Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in Japanese case-control samples and the NIMH Genetics Initiative Bipolar Pedigrees
    • Ohtsuki T, Ishiguro H, Detera-Wadleigh SD, Toyota T, Shimizu H, Yamada K, et al. Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in Japanese case-control samples and the NIMH Genetics Initiative Bipolar Pedigrees. Mol Psychiatry. 2002;7:954-61.
    • (2002) Mol Psychiatry , vol.7 , pp. 954-961
    • Ohtsuki, T.1    Ishiguro, H.2    Detera-Wadleigh, S.D.3    Toyota, T.4    Shimizu, H.5    Yamada, K.6
  • 46
    • 0025074333 scopus 로고
    • Biochemistry and genetics of monoamine oxidase
    • Weyler W, Hsu YP, Breakefield XO. Biochemistry and genetics of monoamine oxidase. Pharmacol Ther. 1990;47:391-417.
    • (1990) Pharmacol Ther , vol.47 , pp. 391-417
    • Weyler, W.1    Hsu, Y.P.2    Breakefield, X.O.3
  • 48
    • 0024673117 scopus 로고
    • Human monoamine oxidase A and B genes map to Xp 11.23 and are deleted in a patient with Norrie disease
    • Lan NC, Heinzmann C, Gal A, Klisak I, Orth U, Lai E, et al. Human monoamine oxidase A and B genes map to Xp 11.23 and are deleted in a patient with Norrie disease. Genomics. 1989;4:552-9.
    • (1989) Genomics , vol.4 , pp. 552-559
    • Lan, N.C.1    Heinzmann, C.2    Gal, A.3    Klisak, I.4    Orth, U.5    Lai, E.6
  • 49
    • 0026668462 scopus 로고
    • Organization of the human monoamine oxidase genes and long-range physical mapping around them
    • Chen ZY, Powell JF, Hsu YP, Breakefield XO, Craig IW. Organization of the human monoamine oxidase genes and long-range physical mapping around them. Genomics. 1992;14:75-82.
    • (1992) Genomics , vol.14 , pp. 75-82
    • Chen, Z.Y.1    Powell, J.F.2    Hsu, Y.P.3    Breakefield, X.O.4    Craig, I.W.5
  • 50
    • 0031711343 scopus 로고    scopus 로고
    • A functional polymorphism in the monoamine oxidase A gene promoter
    • Sabol SZ, Hu S, Hamer D. A functional polymorphism in the monoamine oxidase A gene promoter. Hum Genet. 1998;103:273-9.
    • (1998) Hum Genet , vol.103 , pp. 273-279
    • Sabol, S.Z.1    Hu, S.2    Hamer, D.3
  • 52
    • 0027442475 scopus 로고
    • Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A
    • Brunner HG, Nelen M, Breakefield XO, Ropers HH, van Oost BA. Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Science. 1993;262:578-80.
    • (1993) Science , vol.262 , pp. 578-580
    • Brunner, H.G.1    Nelen, M.2    Breakefield, X.O.3    Ropers, H.H.4    Van Oost, B.A.5
  • 53
    • 0026742041 scopus 로고
    • Characterization of a highly polymorphic region near the first exon of the human MAOA gene containing a GT dinucleotide and a novel VNTR motif
    • Hinds HL, Hendriks RW, Craig IW, Chen ZY. Characterization of a highly polymorphic region near the first exon of the human MAOA gene containing a GT dinucleotide and a novel VNTR motif. Genomics. 1992;13:896-7.
    • (1992) Genomics , vol.13 , pp. 896-897
    • Hinds, H.L.1    Hendriks, R.W.2    Craig, I.W.3    Chen, Z.Y.4
  • 54
    • 0029089851 scopus 로고
    • Evidence for a genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder
    • Lim LC, Powell J, Sham P, Castle D, Hunt N, Murray R, et al. Evidence for a genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder. Am J Med Genet. 1995;60:325-31.
    • (1995) Am J Med Genet , vol.60 , pp. 325-331
    • Lim, L.C.1    Powell, J.2    Sham, P.3    Castle, D.4    Hunt, N.5    Murray, R.6
  • 55
    • 0028843111 scopus 로고
    • Possible association between monoamine oxidase A gene and bipolar affective disorder
    • Kawada Y, Hattori M, Dai XY, Nanko S. Possible association between monoamine oxidase A gene and bipolar affective disorder. Am J Hum Genet. 1995;56:335-6.
    • (1995) Am J Hum Genet , vol.56 , pp. 335-336
    • Kawada, Y.1    Hattori, M.2    Dai, X.Y.3    Nanko, S.4
  • 56
    • 0029942212 scopus 로고    scopus 로고
    • Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: Analysis and meta-analysis
    • Rubinsztein DC, Leggo J, Goodburn S, Walsh C, Jain S, Paykel ES. Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: analysis and meta-analysis. Hum Mol Genet. 1996;5:779-82.
    • (1996) Hum Mol Genet , vol.5 , pp. 779-782
    • Rubinsztein, D.C.1    Leggo, J.2    Goodburn, S.3    Walsh, C.4    Jain, S.5    Paykel, E.S.6
  • 57
    • 12944257360 scopus 로고    scopus 로고
    • Association between bipolar disorder and monoamine oxidase A gene polymorphisms: Results of a multicenter study
    • Preisig M, Bellivier F, Fenton BT, Baud P, Berney A, Courtet P, et al. Association between bipolar disorder and monoamine oxidase A gene polymorphisms: results of a multicenter study. Am J Psychiatry. 2000;157:948-55.
    • (2000) Am J Psychiatry , vol.157 , pp. 948-955
    • Preisig, M.1    Bellivier, F.2    Fenton, B.T.3    Baud, P.4    Berney, A.5    Courtet, P.6
  • 58
    • 0029092406 scopus 로고
    • No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms
    • Craddock N, Daniels J, Roberts E, Rees M, McGuffin P, Owen MJ. No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms. Am J Med Genet. 1995;60:322-4.
    • (1995) Am J Med Genet , vol.60 , pp. 322-324
    • Craddock, N.1    Daniels, J.2    Roberts, E.3    Rees, M.4    McGuffin, P.5    Owen, M.J.6
  • 61
    • 0035825979 scopus 로고    scopus 로고
    • Association analysis of the functional monoamine oxidase a gene promoter polymorphism in psychiatric disorders
    • Syagailo YV, Stober G, GraBle M, Reimer E, Knapp M, Jungkunz G, et al. Association analysis of the functional monoamine oxidase a gene promoter polymorphism in psychiatric disorders. Am J Med Genet. 2001;105:168-171.
    • (2001) Am J Med Genet , vol.105 , pp. 168-171
    • Syagailo, Y.V.1    Stober, G.2    GraBle, M.3    Reimer, E.4    Knapp, M.5    Jungkunz, G.6
  • 62
    • 0029157267 scopus 로고
    • Association analysis of the monoamine oxidase A gene in bipolar affective disorder by using family-based internal controls
    • Nothen MM, Eggermann K, Albus M, Borrmann M, Rietschel M, Korner J, et al. Association analysis of the monoamine oxidase A gene in bipolar affective disorder by using family-based internal controls. Am J Hum Genet. 1995;57:975-8.
    • (1995) Am J Hum Genet , vol.57 , pp. 975-978
    • Nothen, M.M.1    Eggermann, K.2    Albus, M.3    Borrmann, M.4    Rietschel, M.5    Korner, J.6
  • 63
    • 0030866457 scopus 로고    scopus 로고
    • Genetic association between monoamine oxidase and manic-depressive illness: Comparison of relative risk and haplotype relative risk data
    • Parsian A, Todd RD. Genetic association between monoamine oxidase and manic-depressive illness: comparison of relative risk and haplotype relative risk data. Am J Med Genet. 1997;74:475-9.
    • (1997) Am J Med Genet , vol.74 , pp. 475-479
    • Parsian, A.1    Todd, R.D.2
  • 65
    • 18744402483 scopus 로고    scopus 로고
    • Monoamine oxidase a and tryptophan hydroxylase gene polymorphisms: Are they associated with bipolar disorder?
    • Preisig M, Ferrero F, Malafosse A. Monoamine oxidase a and tryptophan hydroxylase gene polymorphisms: are they associated with bipolar disorder? Am J Pharmacogenomics. 2005;5:45-52.
    • (2005) Am J Pharmacogenomics , vol.5 , pp. 45-52
    • Preisig, M.1    Ferrero, F.2    Malafosse, A.3
  • 66
    • 1642469628 scopus 로고    scopus 로고
    • The serotonin transporter is a potential susceptibility factor for bipolar affective disorder
    • Collier DA, Arranz MJ, Sham P, Battersby S, Vallada H, Gill P, et al. The serotonin transporter is a potential susceptibility factor for bipolar affective disorder. Neuroreport. 1996;7:1675-9.
    • (1996) Neuroreport , vol.7 , pp. 1675-1679
    • Collier, D.A.1    Arranz, M.J.2    Sham, P.3    Battersby, S.4    Vallada, H.5    Gill, P.6
  • 67
    • 0000130367 scopus 로고    scopus 로고
    • Association between bipolar disorder and the VNTR polymorphism in intron 2 of the human serotonin transporter gene (HSERT)
    • Craddock N, Rees M, Norton N, Feldman E, McGuffin P, Owen MJ. Association between bipolar disorder and the VNTR polymorphism in intron 2 of the human serotonin transporter gene (HSERT). Psychiatr Genet. 1996;6:147.
    • (1996) Psychiatr Genet , vol.6 , pp. 147
    • Craddock, N.1    Rees, M.2    Norton, N.3    Feldman, E.4    McGuffin, P.5    Owen, M.J.6
  • 68
    • 0034727432 scopus 로고    scopus 로고
    • Variation at the serotonin transporter gene influences susceptibility to bipolar affective puerperal psychosis
    • Coyle N, Jones I, Robertson E, Lendon C, Craddock N. Variation at the serotonin transporter gene influences susceptibility to bipolar affective puerperal psychosis. Lancet. 2000;356:1490-1.
    • (2000) Lancet , vol.356 , pp. 1490-1491
    • Coyle, N.1    Jones, I.2    Robertson, E.3    Lendon, C.4    Craddock, N.5
  • 71
    • 0032872472 scopus 로고    scopus 로고
    • Bipolar disorder and the serotonin transporter gene: A family-based association study
    • Kirov G, Rees M, Jones I, MacCandless F, Owen MJ, Craddock N. Bipolar disorder and the serotonin transporter gene: a family-based association study. Psychol Med. 1999;29:1249-54.
    • (1999) Psychol Med , vol.29 , pp. 1249-1254
    • Kirov, G.1    Rees, M.2    Jones, I.3    MacCandless, F.4    Owen, M.J.5    Craddock, N.6
  • 72
    • 0032492164 scopus 로고    scopus 로고
    • Analysis and meta-analysis of two serotonin transporter gene polymorphisms in bipolar and unipolar affective disorders
    • Furlong RA, Ho L, Walsh C, Rubinsztein JS, Jain S, Paykel ES, et al. Analysis and meta-analysis of two serotonin transporter gene polymorphisms in bipolar and unipolar affective disorders. Am J Med Genet. 1998;81:58-63.
    • (1998) Am J Med Genet , vol.81 , pp. 58-63
    • Furlong, R.A.1    Ho, L.2    Walsh, C.3    Rubinsztein, J.S.4    Jain, S.5    Paykel, E.S.6
  • 73
    • 12944312689 scopus 로고    scopus 로고
    • Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders
    • Lasky-Su JA, Faraone SV, Glatt SJ, Tsuang MT. Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders. Am J Med Genet B (Neuropsychiatr Genet). 2005;133:110-5.
    • (2005) Am J Med Genet B (Neuropsychiatr Genet) , vol.133 , pp. 110-115
    • Lasky-Su, J.A.1    Faraone, S.V.2    Glatt, S.J.3    Tsuang, M.T.4
  • 74
    • 28844446748 scopus 로고    scopus 로고
    • No association of serotonin transporter gene (SLC6A4) with schizophrenia and bipolar disorder in Japanese patients: Association analysis based on linkage disequilibrium
    • Ikeda M, Iwata N, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, et al. No association of serotonin transporter gene (SLC6A4) with schizophrenia and bipolar disorder in Japanese patients: association analysis based on linkage disequilibrium. J Neural Transm. 2005;5:5.
    • (2005) J Neural Transm , vol.5 , pp. 5
    • Ikeda, M.1    Iwata, N.2    Suzuki, T.3    Kitajima, T.4    Yamanouchi, Y.5    Kinoshita, Y.6
  • 75
    • 0034606327 scopus 로고    scopus 로고
    • Multimarker haplotypes within the serotonin transporter gene suggest evidence of an association with bipolar disorder
    • Mynett-Johnson L, Kealey C, Claffey E, Curtis D, Bouchier-Hayes L, Powell C, et al. Multimarker haplotypes within the serotonin transporter gene suggest evidence of an association with bipolar disorder. Am J Med Genet. 2000;96:845-9.
    • (2000) Am J Med Genet , vol.96 , pp. 845-849
    • Mynett-Johnson, L.1    Kealey, C.2    Claffey, E.3    Curtis, D.4    Bouchier-Hayes, L.5    Powell, C.6
  • 77
    • 0034640713 scopus 로고    scopus 로고
    • Lack of linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and bipolar disorder
    • Mundo E, Walker M, Tims H, Macciardi F, Kennedy JL. Lack of linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and bipolar disorder. Am J Med Genet. 2000;96:379-83.
    • (2000) Am J Med Genet , vol.96 , pp. 379-383
    • Mundo, E.1    Walker, M.2    Tims, H.3    Macciardi, F.4    Kennedy, J.L.5
  • 78
    • 0033974338 scopus 로고    scopus 로고
    • The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants
    • Nakamura M, Ueno S, Sano A, Tanabe H. The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants. Mol Psychiatry. 2000;5:32-8.
    • (2000) Mol Psychiatry , vol.5 , pp. 32-38
    • Nakamura, M.1    Ueno, S.2    Sano, A.3    Tanabe, H.4
  • 79
    • 0028894185 scopus 로고
    • Linkage disequilibrium as a gene-mapping tool
    • Jorde LB. Linkage disequilibrium as a gene-mapping tool. American Journal of Human Genetics. 1995;56:11-4.
    • (1995) American Journal of Human Genetics , vol.56 , pp. 11-14
    • Jorde, L.B.1
  • 82
    • 0038054362 scopus 로고    scopus 로고
    • Rationale, design, and methods of the systematic treatment enhancement program for bipolar disorder (STEP-BD)
    • Sachs GS, Thase ME, Otto MW, Bauer M, Miklowitz D, Wisniewski SR, et al. Rationale, design, and methods of the systematic treatment enhancement program for bipolar disorder (STEP-BD). Biol Psychiatry. 2003;53:1028-42.
    • (2003) Biol Psychiatry , vol.53 , pp. 1028-1042
    • Sachs, G.S.1    Thase, M.E.2    Otto, M.W.3    Bauer, M.4    Miklowitz, D.5    Wisniewski, S.R.6
  • 83
    • 0032421570 scopus 로고    scopus 로고
    • The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10
    • quiz 34-57.
    • Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry. 1998;59(Suppl. 20):22-33;quiz 34-57.
    • (1998) J Clin Psychiatry , vol.59 , Issue.20 SUPPL. , pp. 22-33
    • Sheehan, D.V.1    Lecrubier, Y.2    Sheehan, K.H.3    Amorim, P.4    Janavs, J.5    Weiller, E.6
  • 85
    • 85047695697 scopus 로고    scopus 로고
    • Transmission disequilibrium mapping at the serotonin transporter gene (SLC6A4) region in autistic disorder
    • Kim SJ, Cox N, Courchesne R, Lord C, Corsello C, Akshoomoff N, et al. Transmission disequilibrium mapping at the serotonin transporter gene (SLC6A4) region in autistic disorder. Mol Psychiatry. 2002;7:278-88.
    • (2002) Mol Psychiatry , vol.7 , pp. 278-288
    • Kim, S.J.1    Cox, N.2    Courchesne, R.3    Lord, C.4    Corsello, C.5    Akshoomoff, N.6
  • 87
    • 0032231941 scopus 로고    scopus 로고
    • PedCheck: A program for identification of genotype incompatibilties in linakge analysis
    • O'Connell JR, Weeks DE. PedCheck: a program for identification of genotype incompatibilties in linakge analysis. American Journal of Human Genetics. 1998;63:259-266.
    • (1998) American Journal of Human Genetics , vol.63 , pp. 259-266
    • O'Connell, J.R.1    Weeks, D.E.2
  • 88
    • 0033786787 scopus 로고    scopus 로고
    • Linkage disequilibrium and the search for complex disease genes
    • Jorde LB. Linkage disequilibrium and the search for complex disease genes. Genome Res. 2000;10:1435-44.
    • (2000) Genome Res , vol.10 , pp. 1435-1444
    • Jorde, L.B.1
  • 89
    • 0023796209 scopus 로고
    • On measures of gametic disequilibrium
    • Lewontin RC. On measures of gametic disequilibrium. Genetics. 1988;120:849-52.
    • (1988) Genetics , vol.120 , pp. 849-852
    • Lewontin, R.C.1
  • 90
    • 0036137130 scopus 로고    scopus 로고
    • Linkage disequilibrium and the mapping of complex human traits
    • Weiss KM, Clark AG. Linkage disequilibrium and the mapping of complex human traits. Trends Genet. 2002;18:19-24.
    • (2002) Trends Genet , vol.18 , pp. 19-24
    • Weiss, K.M.1    Clark, A.G.2
  • 91
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Epub. 2004 Aug 05
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263-5, Epub. 2004 Aug 05.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 92
    • 0029150074 scopus 로고
    • A comparison of linkage disequilibrium measures for fine-scale mapping
    • Devlin B, Risch N. A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics. 1995;29:311-22.
    • (1995) Genomics , vol.29 , pp. 311-322
    • Devlin, B.1    Risch, N.2
  • 94
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet. 1995;11:241-247.
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 95
    • 0041857847 scopus 로고    scopus 로고
    • Pedigree disequilibrium tests for multilocus haplotypes
    • Dudbridge F. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol. 2003;25:115-21.
    • (2003) Genet Epidemiol , vol.25 , pp. 115-121
    • Dudbridge, F.1
  • 96
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin B, Roeder K. Genomic control for association studies. Biometrics. 1999;55:997-1004.
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 97
    • 0034644955 scopus 로고    scopus 로고
    • An association study of bipolar mood disorder (type I) with the 5-HTTLPR serotonin transporter polymorphism in a human population isolate from Colombia
    • Ospina-Duque J, Duque C, Carvajal-Carmona L, Ortiz-Barrientos D, Soto I, Pineda N, et al. An association study of bipolar mood disorder (type I) with the 5-HTTLPR serotonin transporter polymorphism in a human population isolate from Colombia. Neurosci Lett. 2000;292:199-202.
    • (2000) Neurosci Lett , vol.292 , pp. 199-202
    • Ospina-Duque, J.1    Duque, C.2    Carvajal-Carmona, L.3    Ortiz-Barrientos, D.4    Soto, I.5    Pineda, N.6
  • 98
    • 2442696545 scopus 로고    scopus 로고
    • Serotonin transporter 5HTTLPR polymorphism and affective disorders: No evidence of association in a large European multicenter study
    • Mendlewicz J, Massat I, Souery D, Del-Favero J, Oruc L, Nothen MM, et al. Serotonin transporter 5HTTLPR polymorphism and affective disorders: no evidence of association in a large European multicenter study. Eur J Hum Genet. 2004;12:377-82. Write to the Help Desk NCBI | NLM | NIH Department of Health & Human Services Privacy Statement | Freedom of Information Act | Disclaimer.
    • (2004) Eur J Hum Genet , vol.12 , pp. 377-382
    • Mendlewicz, J.1    Massat, I.2    Souery, D.3    Del-Favero, J.4    Oruc, L.5    Nothen, M.M.6
  • 99
    • 0032492212 scopus 로고    scopus 로고
    • Serotonin transporter (5-HTT) gene polymorphisms are not associated with susceptibility to mood disorders
    • Hoehe MR, Wendel B, Grunewald I, Chiaroni P, Levy N, Morris-Rosendahl D, et al. Serotonin transporter (5-HTT) gene polymorphisms are not associated with susceptibility to mood disorders. Am J Med Genet. 1998;81:1-3.
    • (1998) Am J Med Genet , vol.81 , pp. 1-3
    • Hoehe, M.R.1    Wendel, B.2    Grunewald, I.3    Chiaroni, P.4    Levy, N.5    Morris-Rosendahl, D.6
  • 100
    • 0032191026 scopus 로고    scopus 로고
    • Functional polymorphism in the serotonin transporter promoter at the SLC6A4 locus and mood disorders
    • Ohara K, Nagai M, Tsukamoto T, Tani K, Suzuki Y. Functional polymorphism in the serotonin transporter promoter at the SLC6A4 locus and mood disorders. Biol Psychiatry. 1998;44:550-4.
    • (1998) Biol Psychiatry , vol.44 , pp. 550-554
    • Ohara, K.1    Nagai, M.2    Tsukamoto, T.3    Tani, K.4    Suzuki, Y.5
  • 101
    • 17344391692 scopus 로고    scopus 로고
    • Serotonin transporter gene and risk for bipolar affective disorder: An association study in Spanish population
    • Gutierrez B, Arranz MJ, Collier DA, Valles V, Guillamat R, Bertranpetit J, et al. Serotonin transporter gene and risk for bipolar affective disorder: an association study in Spanish population. Biol Psychiatry. 1998;43:843-7.
    • (1998) Biol Psychiatry , vol.43 , pp. 843-847
    • Gutierrez, B.1    Arranz, M.J.2    Collier, D.A.3    Valles, V.4    Guillamat, R.5    Bertranpetit, J.6
  • 102
    • 0028981182 scopus 로고
    • An extended transmission/disequilibrium test (TDT) for multi-allele marker loci
    • Sham PC, Curtis D. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Ann Hum Genet. 1995;59(Pt 3):323-36.
    • (1995) Ann Hum Genet , vol.59 , Issue.3 PART , pp. 323-336
    • Sham, P.C.1    Curtis, D.2
  • 103
    • 0033168224 scopus 로고    scopus 로고
    • Transmission disequilibrium test (TDT) when only one parent is available: The 1-TDT
    • Sun F, Flanders WD, Yang Q, Khoury MJ. Transmission disequilibrium test (TDT) when only one parent is available: the 1-TDT. Am J Epidemiology. 1999;150:97-104.
    • (1999) Am J Epidemiology , vol.150 , pp. 97-104
    • Sun, F.1    Flanders, W.D.2    Yang, Q.3    Khoury, M.J.4
  • 104
    • 0029940593 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism and affective disorder
    • Kunugi H, Tatsumi M, Sakai T, Hattori M, Nanko S. Serotonin transporter gene polymorphism and affective disorder [letter; comment]. Lancet. 1996;347:1340.
    • (1996) Lancet , vol.347 , pp. 1340
    • Kunugi, H.1    Tatsumi, M.2    Sakai, T.3    Hattori, M.4    Nanko, S.5
  • 106
    • 0031229750 scopus 로고    scopus 로고
    • Association studies of bipolar disorder at the human serotonin transporter gene (hSERT; 5HTT)
    • Rees M, Norton N, Jones I, McCandless F, Scourfield J, Holmans P, et al. Association studies of bipolar disorder at the human serotonin transporter gene (hSERT; 5HTT). Mol Psychiatry. 1997;2:398-402.
    • (1997) Mol Psychiatry , vol.2 , pp. 398-402
    • Rees, M.1    Norton, N.2    Jones, I.3    McCandless, F.4    Scourfield, J.5    Holmans, P.6
  • 107
    • 0033949921 scopus 로고    scopus 로고
    • Analysis of the serotonin transporter polymorphism (5-HTTLPR) in Brazilian patients affected by dysthymia, major depression and bipolar disorder
    • Oliveira JR, Carvalho DR, Pontual D, Gallindo RM, Sougey EB, Gentil V, et al. Analysis of the serotonin transporter polymorphism (5-HTTLPR) in Brazilian patients affected by dysthymia, major depression and bipolar disorder. Mol Psychiatry. 2000;5:348-9.
    • (2000) Mol Psychiatry , vol.5 , pp. 348-349
    • Oliveira, J.R.1    Carvalho, D.R.2    Pontual, D.3    Gallindo, R.M.4    Sougey, E.B.5    Gentil, V.6


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