메뉴 건너뛰기




Volumn 32, Issue 11, 2005, Pages 1115-1127

Identification of potential genes regulated by DNA methyltransferase 3B in a hepatocellular carcinoma cell line by RNA interference and microarray analysis

Author keywords

DNMT3B; Hepatocellular carcinoma; Methyltransferase; RNA interference

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; COMPLEMENTARY DNA; DNA METHYLTRANSFERASE 3B; METHYL CPG BINDING PROTEIN 3; NOTCH1 RECEPTOR; NUCLEIC ACID BINDING PROTEIN; PLASMID VECTOR; PROTEIN; PROTEIN FACL4; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WNT PROTEIN; WNT11 PROTEIN;

EID: 28644433852     PISSN: 03794172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (7)

References (41)
  • 1
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones P A, Laird P W. Cancer epigenetics comes of age. Nature Genetics, 1999, 21(2): 163-167.
    • (1999) Nature Genetics , vol.21 , Issue.2 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 2
    • 0023848637 scopus 로고
    • Reduced genomic 5-methylcytosine content in human colonic neoplasia
    • Feinberg A P,Gehrke C W, Kuo K C, Ehrlich M. Reduced genomic 5-methylcytosine content in human colonic neoplasia. Cancer Res, 1988, 48(5): 1159-1161.
    • (1988) Cancer Res , vol.48 , Issue.5 , pp. 1159-1161
    • Feinberg, A.P.1    Gehrke, C.W.2    Kuo, K.C.3    Ehrlich, M.4
  • 3
    • 0035110005 scopus 로고    scopus 로고
    • Methylation status of c-fms oncogene in HCC and its relationship with clinical pathology
    • Cui J, Yang D H, Bi X J, Fan Z R. Methylation status of c-fms oncogene in HCC and its relationship with clinical pathology. World J Gastroentero, 2001, 7(1): 136-139.
    • (2001) World J Gastroentero , vol.7 , Issue.1 , pp. 136-139
    • Cui, J.1    Yang, D.H.2    Bi, X.J.3    Fan, Z.R.4
  • 5
    • 0141606726 scopus 로고    scopus 로고
    • Effects of DNA methylation on expression of tumor suppressor genes and proto-oncogene in human colon cancer cell lines
    • Fang J Y, Lu J, Chen Y X, Yang L. Effects of DNA methylation on expression of tumor suppressor genes and proto-oncogene in human colon cancer cell lines. World J Gastroenterol, 2003, 9(9): 1976-1980.
    • (2003) World J Gastroenterol , vol.9 , Issue.9 , pp. 1976-1980
    • Fang, J.Y.1    Lu, J.2    Chen, Y.X.3    Yang, L.4
  • 6
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman J G, Mao L, Lee D J, Gabrielson E, Burger P C, Baylin S B, Sidransky D. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med, 1995, 1(7): 686-692.
    • (1995) Nat Med , vol.1 , Issue.7 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 7
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all human cancers
    • Herman J G, Merlo A, Mao L, Lapidus R G, Issa J P J, Davidson N E, Sidransky D, Baylin S B. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all human cancers. Cancer Res, 1995, 55(20): 4525-4530.
    • (1995) Cancer Res , vol.55 , Issue.20 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.J.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 8
    • 0242527188 scopus 로고    scopus 로고
    • Relationship between CpG methylation of p16 gene and sporatic colorectal cancer
    • YANG Yu-Hua, HE Xiao-Bing, ZHANG Feng-Rui, ZHANG Jian-Qiong, XIE Wei. Relationship between CpG methylation of p16 gene and sporatic colorectal cancer. Acta Genetica Sinca, 2003, 30(11):1061-1064.
    • (2003) Acta Genetica Sinca , vol.30 , Issue.11 , pp. 1061-1064
    • Yu-Hua, Y.1    Xiao-Bing, H.E.2    Feng-Rui, Z.3    Jian-Qiong, Z.4    Wei, X.I.E.5
  • 9
    • 0035863455 scopus 로고    scopus 로고
    • DNA methyltransferase expression and DNA methylation of CpG islands and peri-centromeric satellite regions in human colorectal and stomach cancers
    • Kanai Y, Ushijima S, Kondo Y, Nakanishi Y, Hirohashi S. DNA methyltransferase expression and DNA methylation of CpG islands and peri-centromeric satellite regions in human colorectal and stomach cancers. Int J Cancer, 2001, 91 (2): 205-212.
    • (2001) Int J Cancer , vol.91 , Issue.2 , pp. 205-212
    • Kanai, Y.1    Ushijima, S.2    Kondo, Y.3    Nakanishi, Y.4    Hirohashi, S.5
  • 10
    • 0038325528 scopus 로고    scopus 로고
    • Concerted promoter hypermethylation of hMLH1, p16INK4A, and E-cadherin in gastric carcinomas with microsatellite instability
    • Kim H, Kim Y H, Kim S E, Kim N G, Noh S H, Kim H. Concerted promoter hypermethylation of hMLH1, p16INK4A, and E-cadherin in gastric carcinomas with microsatellite instability. Journal of pathology, 2003, 200(1): 23-31.
    • (2003) Journal of Pathology , vol.200 , Issue.1 , pp. 23-31
    • Kim, H.1    Kim, Y.H.2    Kim, S.E.3    Kim, N.G.4    Noh, S.H.5
  • 11
    • 0035870248 scopus 로고    scopus 로고
    • A gene hypermethylation profile of human cancer
    • Esteller M, Corn P G, Baylin S B, Herman J G. A gene hypermethylation profile of human cancer. Cancer Res, 2001, 61(8): 3225-3229.
    • (2001) Cancer Res , vol.61 , Issue.8 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3    Herman, J.G.4
  • 12
    • 0033588232 scopus 로고    scopus 로고
    • Down-regulation of human DNA-(cytosine-5) methyltransferase induces cell cycle regulators p16(ink4A) and p21 (WAF/Cip1) by distinct mechanisms
    • Fournel M, Sapieha P, Beaulieu N, Besterman J M, MacLeod A R. Down-regulation of human DNA-(cytosine-5) methyltransferase induces cell cycle regulators p16(ink4A) and p21 (WAF/Cip1) by distinct mechanisms. J Biol Chem, 1999, 274(34): 24250-24256.
    • (1999) J Biol Chem , vol.274 , Issue.34 , pp. 24250-24256
    • Fournel, M.1    Sapieha, P.2    Beaulieu, N.3    Besterman, J.M.4    MacLeod, A.R.5
  • 13
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor T H. The DNA methyltransferases of mammals. Hum Mol Genet, 2000, 9(16): 2395-2402.
    • (2000) Hum Mol Genet , vol.9 , Issue.16 , pp. 2395-2402
    • Bestor, T.H.1
  • 14
    • 0035962631 scopus 로고    scopus 로고
    • DNA methylation, methyltransferases and cancer
    • Robertson K D. DNA methylation, methyltransferases and cancer. Oncogene, 2001, 20(24): 3139-3155.
    • (2001) Oncogene , vol.20 , Issue.24 , pp. 3139-3155
    • Robertson, K.D.1
  • 15
    • 0037068372 scopus 로고    scopus 로고
    • DNA methylation and chromatin-unraveling the tangled web
    • Robertson K D. DNA methylation and chromatin-unraveling the tangled web. Oncogene, 2002, 21(35): 5361-5379.
    • (2002) Oncogene , vol.21 , Issue.35 , pp. 5361-5379
    • Robertson, K.D.1
  • 17
    • 0035930660 scopus 로고    scopus 로고
    • Dnmt3L and the establishment of maternal genomic imprints
    • Bourc'his D, Xu G L, Lin C S, Bollman B, Bestor T H. Dnmt3L and the establishment of maternal genomic imprints. Science, 2001, 294(5551): 2536-2539.
    • (2001) Science , vol.294 , Issue.5551 , pp. 2536-2539
    • Bourc'His, D.1    Xu, G.L.2    Lin, C.S.3    Bollman, B.4    Bestor, T.H.5
  • 18
    • 0031860739 scopus 로고    scopus 로고
    • Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • Okano M, Xie S, Li E. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nature Genet, 1998, 19(3): 219-220
    • (1998) Nature Genet , vol.19 , Issue.3 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 19
    • 0033153303 scopus 로고    scopus 로고
    • The human DNA methyltransferases (DNMTs) 1,3a and 3b:coordinate mRNA expression in normal tissues and overexpression in tumors
    • Robertson K D, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales F A, Jones P A. The human DNA methyltransferases (DNMTs) 1,3a and 3b:coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res, 1999, 27(11): 2291-2298.
    • (1999) Nucleic Acids Res , vol.27 , Issue.11 , pp. 2291-2298
    • Robertson, K.D.1    Uzvolgyi, E.2    Liang, G.3    Talmadge, C.4    Sumegi, J.5    Gonzales, F.A.6    Jones, P.A.7
  • 23
    • 0026076727 scopus 로고
    • Abnormal patterns of DNA methylation in human neoplasia: Potential consequences for tumor progression
    • Baylin S B, Makos M, Wu J J, Yen R W, de Bustros A, Vertino P, Nelkin B D. Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumor progression. Cancer Cells, 1991, 3(10): 383-390.
    • (1991) Cancer Cells , vol.3 , Issue.10 , pp. 383-390
    • Baylin, S.B.1    Makos, M.2    Wu, J.J.3    Yen, R.W.4    De Bustros, A.5    Vertino, P.6    Nelkin, B.D.7
  • 25
    • 0037349716 scopus 로고    scopus 로고
    • Methylation and mutation analysis of p16 gene in gastric cancer
    • Ding Y, Le X P, Zhang Q X, Du P. Methylation and mutation analysis of p16 gene in gastric cancer. World J Gastroenterol, 2003, 9(3): 423-426.
    • (2003) World J Gastroenterol , vol.9 , Issue.3 , pp. 423-426
    • Ding, Y.1    Le, X.P.2    Zhang, Q.X.3    Du, P.4
  • 26
    • 0029973718 scopus 로고    scopus 로고
    • De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase
    • Vertino P M, Yen R W, Gao J, Baylin S B. De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)- methyltransferase. Mol Cell Biol, 1996, 16(8): 4555-4565.
    • (1996) Mol Cell Biol , vol.16 , Issue.8 , pp. 4555-4565
    • Vertino, P.M.1    Yen, R.W.2    Gao, J.3    Baylin, S.B.4
  • 27
    • 0027504621 scopus 로고
    • Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells
    • Wu J, Issa J, Herman J, Bassett Jr D E, Nelkin B D, Baylin S B. Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells. Proc Natl Acad Sci USA, 1993, 90(19): 8891-8895.
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.19 , pp. 8891-8895
    • Wu, J.1    Issa, J.2    Herman, J.3    Bassett Jr., D.E.4    Nelkin, B.D.5    Baylin, S.B.6
  • 28
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell D W, Haber D A, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell, 1999, 99 (3): 247-257.
    • (1999) Cell , vol.99 , Issue.3 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 29
    • 0036803302 scopus 로고    scopus 로고
    • Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis
    • Watanabe D, Suetake I, Tada T, Tajima S. Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis. Mech Dev, 2002, 118(1-2): 187-190.
    • (2002) Mech Dev , vol.118 , Issue.1-2 , pp. 187-190
    • Watanabe, D.1    Suetake, I.2    Tada, T.3    Tajima, S.4
  • 33
    • 0025894092 scopus 로고
    • Cadherin cell adhesion receptors as a morphogenetic regulator
    • Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science, 1991, 251(5000): 1451-1455.
    • (1991) Science , vol.251 , Issue.5000 , pp. 1451-1455
    • Takeichi, M.1
  • 34
    • 0037310198 scopus 로고    scopus 로고
    • Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma
    • Gupta A, Godwin A K, Vanderveer L, Lu A, Liu J. Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma. Cancer Res, 2003, 63(3): 664-673.
    • (2003) Cancer Res , vol.63 , Issue.3 , pp. 664-673
    • Gupta, A.1    Godwin, A.K.2    Vanderveer, L.3    Lu, A.4    Liu, J.5
  • 35
    • 1842583600 scopus 로고    scopus 로고
    • Demethylation of the synuclein gamma gene CpG islands in primary gastric cancers and gastric cancer cell lines
    • Yanagawa N, Tamura G, Honda T, Endoh M, Nishizuka S, Motoyama T. Demethylation of the synuclein gamma gene CpG islands in primary gastric cancers and gastric cancer cell lines. Clin Cancer Res, 2004, 10(7): 2447-2451.
    • (2004) Clin Cancer Res , vol.10 , Issue.7 , pp. 2447-2451
    • Yanagawa, N.1    Tamura, G.2    Honda, T.3    Endoh, M.4    Nishizuka, S.5    Motoyama, T.6
  • 36
    • 2942726272 scopus 로고    scopus 로고
    • Wnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells
    • Ouko L, Ziegler T R, Gu L H, Eisenberg L M, Yang V W. Wnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells. J Biol Chem, 2004, 279(25): 26707-26715.
    • (2004) J Biol Chem , vol.279 , Issue.25 , pp. 26707-26715
    • Ouko, L.1    Ziegler, T.R.2    Gu, L.H.3    Eisenberg, L.M.4    Yang, V.W.5
  • 37
    • 0038758048 scopus 로고    scopus 로고
    • Fatty acid-CoA ligase 4 is overexpressed in human hepatocellular carcinoma
    • Sung Y K, Hwang S Y, Park M K, Bae H I, Kim W H, Kim J C, Kim M. Fatty acid-CoA ligase 4 is overexpressed in human hepatocellular carcinoma. Cancer Sci, 2003, 94(5): 421-424.
    • (2003) Cancer Sci , vol.94 , Issue.5 , pp. 421-424
    • Sung, Y.K.1    Hwang, S.Y.2    Park, M.K.3    Bae, H.I.4    Kim, W.H.5    Kim, J.C.6    Kim, M.7
  • 39
    • 0035933337 scopus 로고    scopus 로고
    • Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: The enzyme modifies DNA in a non-processive manner and also methylates non-CpG sites
    • Gowher H, Jeltsch A. Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG sites. J Mol Biol, 2001, 309(5): 1201-1208.
    • (2001) J Mol Biol , vol.309 , Issue.5 , pp. 1201-1208
    • Gowher, H.1    Jeltsch, A.2
  • 40
    • 0037023761 scopus 로고    scopus 로고
    • Preferential methylation of unmethylated DNA by mammalian de novo DNA methyltransferase Dnmt3a
    • Yokochi T, Robertson K D. Preferential methylation of unmethylated DNA by mammalian de novo DNA methyltransferase Dnmt3a. J Biol Chem, 2002, 277(14): 11735-11745.
    • (2002) J Biol Chem , vol.277 , Issue.14 , pp. 11735-11745
    • Yokochi, T.1    Robertson, K.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.