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Volumn 57, Issue 13 SPEC. ISS., 2005, Pages 1904-1917

ES cell technology: An introduction to genetic manipulation, differentiation and therapeutic cloning

Author keywords

Cell therapy; Differentiation; Drug discovery; Gene targeting; Lineage selection

Indexed keywords

CLONING; DRUG THERAPY; GENETIC ENGINEERING;

EID: 27944509526     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2005.07.018     Document Type: Review
Times cited : (13)

References (104)
  • 1
    • 0342449328 scopus 로고    scopus 로고
    • Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysis
    • U. Muller Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysis Mech. Dev. 82 1999 3 21
    • (1999) Mech. Dev. , vol.82 , pp. 3-21
    • Muller, U.1
  • 2
    • 0028500365 scopus 로고
    • Gene targeting in the mouse
    • D. Melton Gene targeting in the mouse BioEssays 16 1994 633 638
    • (1994) BioEssays , vol.16 , pp. 633-638
    • Melton, D.1
  • 3
    • 0021358883 scopus 로고
    • Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
    • A. Bradley, M. Evans, M. Kaufman, and E. Robertson Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines Nature 309 1984 255 256
    • (1984) Nature , vol.309 , pp. 255-256
    • Bradley, A.1    Evans, M.2    Kaufman, M.3    Robertson, E.4
  • 4
    • 0022461705 scopus 로고
    • Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector
    • E. Robertson, A. Bradley, M. Kuehn, and M. Evans Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector Nature 323 1986 445 447
    • (1986) Nature , vol.323 , pp. 445-447
    • Robertson, E.1    Bradley, A.2    Kuehn, M.3    Evans, M.4
  • 5
    • 25444500139 scopus 로고    scopus 로고
    • Gene-targeting technologies for the study of neurological disorders
    • V. Beglopoulos, and J. Shen Gene-targeting technologies for the study of neurological disorders Neuromol. Med. 6 2004 13 30
    • (2004) Neuromol. Med. , vol.6 , pp. 13-30
    • Beglopoulos, V.1    Shen, J.2
  • 6
    • 16644382855 scopus 로고    scopus 로고
    • Gene targeting and transgenic strategies for the analysis of hematopoietic development in the mouse
    • H.K. Mikkola, and S.H. Orkin Gene targeting and transgenic strategies for the analysis of hematopoietic development in the mouse Methods Mol. Med. 105 2005 3 22
    • (2005) Methods Mol. Med. , vol.105 , pp. 3-22
    • Mikkola, H.K.1    Orkin, S.H.2
  • 7
    • 0019888362 scopus 로고
    • Bacteriophage P1 site-specific recombination: I. Recombination between loxP sites
    • N. Sternberg, and D. Hamilton Bacteriophage P1 site-specific recombination: I. Recombination between loxP sites J. Mol. Biol. 150 1981 467 486
    • (1981) J. Mol. Biol. , vol.150 , pp. 467-486
    • Sternberg, N.1    Hamilton, D.2
  • 8
    • 0028676217 scopus 로고
    • TKO'ed: lox, stock and barrel
    • C. Chambers TKO'ed: lox, stock and barrel BioEssays 16 1994 865 868
    • (1994) BioEssays , vol.16 , pp. 865-868
    • Chambers, C.1
  • 9
    • 0029788269 scopus 로고    scopus 로고
    • Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter
    • L. St-Onge, P. Furth, and P. Gruss Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter N.A.R. 24 1996 3875 3877
    • (1996) N.A.R. , vol.24 , pp. 3875-3877
    • St-Onge, L.1    Furth, P.2    Gruss, P.3
  • 11
    • 0032481124 scopus 로고    scopus 로고
    • Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
    • P. Danielian, D. Muccino, D. Rowitch, S. Michael, and A. McMahon Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase Curr. Biol. 8 1998 1323 1326
    • (1998) Curr. Biol. , vol.8 , pp. 1323-1326
    • Danielian, P.1    Muccino, D.2    Rowitch, D.3    Michael, S.4    McMahon, A.5
  • 12
    • 4644361590 scopus 로고    scopus 로고
    • Inducible mouse models for inherited skin diseases: implications for skin gene therapy
    • M. Arin, and D. Roop Inducible mouse models for inherited skin diseases: implications for skin gene therapy Cells Tissues Organs 177 2004 160 168
    • (2004) Cells Tissues Organs , vol.177 , pp. 160-168
    • Arin, M.1    Roop, D.2
  • 13
    • 0029991362 scopus 로고    scopus 로고
    • Impaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrins
    • E. Hirsch, A. Iglesias, A. Potocnik, U. Hartmann, and R. Fassler Impaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrins Nature 380 1996 171 175
    • (1996) Nature , vol.380 , pp. 171-175
    • Hirsch, E.1    Iglesias, A.2    Potocnik, A.3    Hartmann, U.4    Fassler, R.5
  • 14
    • 0033672656 scopus 로고    scopus 로고
    • Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrow
    • A. Potocnik, C. Brakebusch, and R. Fassler Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrow Immunity 12 2000 653 663
    • (2000) Immunity , vol.12 , pp. 653-663
    • Potocnik, A.1    Brakebusch, C.2    Fassler, R.3
  • 15
    • 0037336820 scopus 로고    scopus 로고
    • Homologous recombination in human embryonic stem cells
    • T. Zwaka, and J. Thomson Homologous recombination in human embryonic stem cells Nat. Biotechnol. 21 2003 319 321
    • (2003) Nat. Biotechnol. , vol.21 , pp. 319-321
    • Zwaka, T.1    Thomson, J.2
  • 16
    • 0031028759 scopus 로고    scopus 로고
    • Mouse models of human disease: Part II. Recent progress and future directions
    • M. Bedell, D. Largaespada, N. Jenkins, and N. Copeland Mouse models of human disease: Part II. Recent progress and future directions Genes Dev. 11 1997 11 43
    • (1997) Genes Dev. , vol.11 , pp. 11-43
    • Bedell, M.1    Largaespada, D.2    Jenkins, N.3    Copeland, N.4
  • 17
    • 0346055155 scopus 로고    scopus 로고
    • BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease
    • M. Ohno, E. Sametsky, L. Younkin, H. Oakley, S. Younkin, M. Citron, R. Vassar, and J. Disterhoft BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease Neuron 41 2004 27 33
    • (2004) Neuron , vol.41 , pp. 27-33
    • Ohno, M.1    Sametsky, E.2    Younkin, L.3    Oakley, H.4    Younkin, S.5    Citron, M.6    Vassar, R.7    Disterhoft, J.8
  • 18
    • 0037382904 scopus 로고    scopus 로고
    • Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes
    • Y. Yang, and B. Seed Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes Nat. Biotechnol. 10 2003 447 451
    • (2003) Nat. Biotechnol. , vol.10 , pp. 447-451
    • Yang, Y.1    Seed, B.2
  • 19
    • 0025847620 scopus 로고
    • Recombinase-mediated gene activation and site-specific integration in mammalian cells
    • S. O'Gorman, D.T. Fox, and G.M. Wahl Recombinase-mediated gene activation and site-specific integration in mammalian cells Science 251 1991 1351 1355
    • (1991) Science , vol.251 , pp. 1351-1355
    • O'Gorman, S.1    Fox, D.T.2    Wahl, G.M.3
  • 21
    • 0036703466 scopus 로고    scopus 로고
    • Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage
    • J.A. Gorski, T. Talley, M. Qiu, L. Puelles, J.L. Rubenstein, and K.R. Jones Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage J. Neurosci. 22 2002 6309 6314
    • (2002) J. Neurosci. , vol.22 , pp. 6309-6314
    • Gorski, J.A.1    Talley, T.2    Qiu, M.3    Puelles, L.4    Rubenstein, J.L.5    Jones, K.R.6
  • 22
    • 0035015769 scopus 로고    scopus 로고
    • Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line
    • R. Constien, A. Forde, B. Liliensiek, H.J. Grone, P. Nawroth, G. Hammerling, and B. Arnold Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line Genesis 30 2001 36 44
    • (2001) Genesis , vol.30 , pp. 36-44
    • Constien, R.1    Forde, A.2    Liliensiek, B.3    Grone, H.J.4    Nawroth, P.5    Hammerling, G.6    Arnold, B.7
  • 25
    • 0025050679 scopus 로고
    • Entrapment vectors: a new tool for mammalian genetics
    • W. Skarnes Entrapment vectors: a new tool for mammalian genetics Biotechnology (NY) 8 9 1990 827 831
    • (1990) Biotechnology (NY) , vol.8 , Issue.9 , pp. 827-831
    • Skarnes, W.1
  • 26
    • 0032090993 scopus 로고    scopus 로고
    • Gene trapping-a preface
    • M. Evans Gene trapping-a preface Dev. Dyn. 212 1998 167 169
    • (1998) Dev. Dyn. , vol.212 , pp. 167-169
    • Evans, M.1
  • 27
    • 0025992469 scopus 로고
    • Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice
    • G. Friedrich, and P. Soriano Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice Genes Dev. 9 1991 1513 1523
    • (1991) Genes Dev. , vol.9 , pp. 1513-1523
    • Friedrich, G.1    Soriano, P.2
  • 28
    • 0030879143 scopus 로고    scopus 로고
    • Evidence for the stochastic integration of gene trap vectors into the mouse germline
    • K. Chowdhury, P. Bonaldo, M. Torres, A. Stoykova, and P. Gruss Evidence for the stochastic integration of gene trap vectors into the mouse germline Nucleic Acids Res. 25 1997 1531 1536
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1531-1536
    • Chowdhury, K.1    Bonaldo, P.2    Torres, M.3    Stoykova, A.4    Gruss, P.5
  • 31
    • 0033572992 scopus 로고    scopus 로고
    • RET: a poly A-trap retrovirus vector for reversible disruption and expression monitoring of genes in living cells
    • Y. Ishida, and P. Leder RET: a poly A-trap retrovirus vector for reversible disruption and expression monitoring of genes in living cells Nucleic Acids Res. 27 1999 e35
    • (1999) Nucleic Acids Res. , vol.27 , pp. 35
    • Ishida, Y.1    Leder, P.2
  • 32
    • 0032795285 scopus 로고    scopus 로고
    • An avian sarcoma/leukosis virus-based gene trap vector for mammalian cells
    • X. Zheng, and S. Hughes An avian sarcoma/leukosis virus-based gene trap vector for mammalian cells J. Virol. 73 1999 6946 6952
    • (1999) J. Virol. , vol.73 , pp. 6946-6952
    • Zheng, X.1    Hughes, S.2
  • 33
    • 0024542052 scopus 로고
    • Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes
    • A. Gossler, A.L. Joyner, J. Rossant, and W.C. Skarnes Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes Science 244 1989 463 465
    • (1989) Science , vol.244 , pp. 463-465
    • Gossler, A.1    Joyner, A.L.2    Rossant, J.3    Skarnes, W.C.4
  • 34
    • 0032505679 scopus 로고    scopus 로고
    • Efficient gene trap screening for novel developmental genes using IRES beta geo vector and in vitro preselection
    • P. Bonaldo, K. Chowdhury, A. Stoykova, M. Torres, and P. Gruss Efficient gene trap screening for novel developmental genes using IRES beta geo vector and in vitro preselection Exp. Cell Res. 244 1998 125 136
    • (1998) Exp. Cell Res. , vol.244 , pp. 125-136
    • Bonaldo, P.1    Chowdhury, K.2    Stoykova, A.3    Torres, M.4    Gruss, P.5
  • 35
    • 0031781469 scopus 로고    scopus 로고
    • Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system
    • A. Stoykova, K. Chowdhury, P. Bonaldo, M. Torres, and P. Gruss Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system Dev. Dyn. 212 1998 198 213
    • (1998) Dev. Dyn. , vol.212 , pp. 198-213
    • Stoykova, A.1    Chowdhury, K.2    Bonaldo, P.3    Torres, M.4    Gruss, P.5
  • 36
    • 0029961757 scopus 로고    scopus 로고
    • Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion
    • J. Chen, A. Nachabah, C. Scherer, P. Ganju, A. Reith, R. Bronson, and H.E. Ruley Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion Oncogene 12 1996 979 988
    • (1996) Oncogene , vol.12 , pp. 979-988
    • Chen, J.1    Nachabah, A.2    Scherer, C.3    Ganju, P.4    Reith, A.5    Bronson, R.6    Ruley, H.E.7
  • 38
    • 0031749959 scopus 로고    scopus 로고
    • Bodenin: a novel murine gene expressed in restricted areas of the brain
    • A.M. Faisst, and P. Gruss Bodenin: a novel murine gene expressed in restricted areas of the brain Dev. Dyn. 212 1998 293 303
    • (1998) Dev. Dyn. , vol.212 , pp. 293-303
    • Faisst, A.M.1    Gruss, P.2
  • 39
    • 0031800261 scopus 로고    scopus 로고
    • Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector
    • P. McClive, G. Pall, K. Newton, M. Lee, J. Mullins, and L. Forrester Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector Dev. Dyn. 212 1998 267 276
    • (1998) Dev. Dyn. , vol.212 , pp. 267-276
    • McClive, P.1    Pall, G.2    Newton, K.3    Lee, M.4    Mullins, J.5    Forrester, L.6
  • 42
    • 0030947962 scopus 로고    scopus 로고
    • Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice
    • D.J. Townley, B.J. Avery, B. Rosen, and W.C. Skarnes Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice Genome Res. 7 1997 293 298
    • (1997) Genome Res. , vol.7 , pp. 293-298
    • Townley, D.J.1    Avery, B.J.2    Rosen, B.3    Skarnes, W.C.4
  • 43
    • 0019427717 scopus 로고
    • A gene chimaera of SV40 and mouse beta-globin is transcribed and properly spliced
    • G. Chu, and P. Sharp A gene chimaera of SV40 and mouse beta-globin is transcribed and properly spliced Nature 289 1981 378 382
    • (1981) Nature , vol.289 , pp. 378-382
    • Chu, G.1    Sharp, P.2
  • 44
    • 0021418696 scopus 로고
    • An SV40 "enhancer trap" incorporates exogenous enhancers or generates enhancers from its own sequences
    • F. Weber, J. de Villiers, and W. Schaffner An SV40 "enhancer trap" incorporates exogenous enhancers or generates enhancers from its own sequences Cell 36 1984 983 992
    • (1984) Cell , vol.36 , pp. 983-992
    • Weber, F.1    De Villiers, J.2    Schaffner, W.3
  • 45
    • 0036903270 scopus 로고    scopus 로고
    • Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation
    • J. Aubert, H. Dunstan, I. Chambers, and A. Smith Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation Nat. Biotechnol. 20 2002 1240 1245
    • (2002) Nat. Biotechnol. , vol.20 , pp. 1240-1245
    • Aubert, J.1    Dunstan, H.2    Chambers, I.3    Smith, A.4
  • 46
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • I. Chambers, D. Colby, M. Robertson, J. Nichols, S. Lee, S. Tweedie, and A. Smith Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells Cell 113 2003 643 655
    • (2003) Cell , vol.113 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3    Nichols, J.4    Lee, S.5    Tweedie, S.6    Smith, A.7
  • 48
    • 0028841640 scopus 로고
    • In vitro differentiation of embryonic stem cells
    • G. Keller In vitro differentiation of embryonic stem cells Curr. Opin. Cell. Biol. 1995 862 869
    • (1995) Curr. Opin. Cell. Biol. , pp. 862-869
    • Keller, G.1
  • 49
    • 0037376793 scopus 로고    scopus 로고
    • Pharmacological potential of embryonic stem cells
    • T. Gorba, and T. Allsopp Pharmacological potential of embryonic stem cells Pharmacol. Res. 47 2003 269 278
    • (2003) Pharmacol. Res. , vol.47 , pp. 269-278
    • Gorba, T.1    Allsopp, T.2
  • 50
    • 1842479021 scopus 로고    scopus 로고
    • The "brainy side" of human embryonic stem cells
    • E. Hornstein, and N. Benvenisty The "brainy side" of human embryonic stem cells J. Neurosci. Res. 76 2004 169 173
    • (2004) J. Neurosci. Res. , vol.76 , pp. 169-173
    • Hornstein, E.1    Benvenisty, N.2
  • 51
    • 0035690493 scopus 로고    scopus 로고
    • Enrichment of neurons and neural precursors from human embryonic stem cells
    • M. Carpenter, M. Inokuma, J. Denham, T. Mutjaba, C. Chiu, and M. Rao Enrichment of neurons and neural precursors from human embryonic stem cells Exp. Neurol. 172 2001 383 397
    • (2001) Exp. Neurol. , vol.172 , pp. 383-397
    • Carpenter, M.1    Inokuma, M.2    Denham, J.3    Mutjaba, T.4    Chiu, C.5    Rao, M.6
  • 55
    • 0035200623 scopus 로고    scopus 로고
    • In vitro differentiation of transplantable neural precursors from human embryonic stem cells
    • S. Zhang, M. Wernig, I. Duncan, O. Brüstle, and J. Thomson In vitro differentiation of transplantable neural precursors from human embryonic stem cells Nat. Biotechnol. 19 2001 1129 1133
    • (2001) Nat. Biotechnol. , vol.19 , pp. 1129-1133
    • Zhang, S.1    Wernig, M.2    Duncan, I.3    Brüstle, O.4    Thomson, J.5
  • 56
    • 0037144701 scopus 로고    scopus 로고
    • Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells
    • C. Xu, S. Police, N. Rao, and M.M. Carpenter Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells Circ. Res. 91 2002 501 508
    • (2002) Circ. Res. , vol.91 , pp. 501-508
    • Xu, C.1    Police, S.2    Rao, N.3    Carpenter, M.M.4
  • 59
    • 0037239195 scopus 로고    scopus 로고
    • Generation of hepatocyte-like cells from human embryonic stem cells
    • L. Rambhatla, C. Chiu, P. Kundu, Y. Peng, and M. Carpenter Generation of hepatocyte-like cells from human embryonic stem cells Cell Transplant 12 2003 1 11
    • (2003) Cell Transplant , vol.12 , pp. 1-11
    • Rambhatla, L.1    Chiu, C.2    Kundu, P.3    Peng, Y.4    Carpenter, M.5
  • 61
    • 0037789540 scopus 로고    scopus 로고
    • Alternative sources of beta cells for cell therapy of diabetes
    • R. Scharfmann Alternative sources of beta cells for cell therapy of diabetes Eur. J. Clin. Invest. 33 2003 595 600
    • (2003) Eur. J. Clin. Invest. , vol.33 , pp. 595-600
    • Scharfmann, R.1
  • 62
    • 0042695568 scopus 로고    scopus 로고
    • Going where the action is: cellular therapy for diabetes mellitus
    • E. Read Going where the action is: cellular therapy for diabetes mellitus Cytotherapy 5 2003 241 242
    • (2003) Cytotherapy , vol.5 , pp. 241-242
    • Read, E.1
  • 64
    • 0347995026 scopus 로고    scopus 로고
    • Human embryonic stem cells as an in vitro model for human vascular development and the induction of vascular differentiation
    • S. Gerecht-Nir, A. Ziskind, S. Cohen, and J. Itskovitz-Eldor Human embryonic stem cells as an in vitro model for human vascular development and the induction of vascular differentiation Lab. Invest. 83 2003 1811 1820
    • (2003) Lab. Invest. , vol.83 , pp. 1811-1820
    • Gerecht-Nir, S.1    Ziskind, A.2    Cohen, S.3    Itskovitz-Eldor, J.4
  • 65
    • 3142776112 scopus 로고    scopus 로고
    • Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties
    • L. Wang, L. Li, F. Shojaei, K. Levac, C. Cerdan, P. Menendez, T. Martin, A. Rouleau, and M. Bhatia Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties Immunity 21 2004 31 41
    • (2004) Immunity , vol.21 , pp. 31-41
    • Wang, L.1    Li, L.2    Shojaei, F.3    Levac, K.4    Cerdan, C.5    Menendez, P.6    Martin, T.7    Rouleau, A.8    Bhatia, M.9
  • 66
    • 0030016231 scopus 로고    scopus 로고
    • Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts
    • M. Klug, M. Soonpaa, G. Young Koh, and L. Field Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts J. Clin. Invest. 98 1996 216 224
    • (1996) J. Clin. Invest. , vol.98 , pp. 216-224
    • Klug, M.1    Soonpaa, M.2    Young Koh, G.3    Field, L.4
  • 67
    • 0023720048 scopus 로고
    • Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
    • J. Pelletier, and N. Sonenberg Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA Nature 334 1988 320 325
    • (1988) Nature , vol.334 , pp. 320-325
    • Pelletier, J.1    Sonenberg, N.2
  • 68
    • 0025883162 scopus 로고
    • Internal initiation of translation mediated by the 5′ leader of a cellular mRNA
    • D. Macejak, and P. Sarnow Internal initiation of translation mediated by the 5′ leader of a cellular mRNA Nature 353 1991 90 94
    • (1991) Nature , vol.353 , pp. 90-94
    • Macejak, D.1    Sarnow, P.2
  • 69
    • 0029102253 scopus 로고
    • Alternative translation initiation of the Moloney murine leukemia virus mRNA controlled by internal ribosome entry involving the p57/PTB splicing factor
    • S. Vagner, A. Waysbort, M. Marenda, M. Gensac, F. Amalric, and A. Prats Alternative translation initiation of the Moloney murine leukemia virus mRNA controlled by internal ribosome entry involving the p57/PTB splicing factor J. Biol. Chem. 270 1995 20376 20383
    • (1995) J. Biol. Chem. , vol.270 , pp. 20376-20383
    • Vagner, S.1    Waysbort, A.2    Marenda, M.3    Gensac, M.4    Amalric, F.5    Prats, A.6
  • 70
    • 0030021166 scopus 로고    scopus 로고
    • Internal initiation of translation directed by the 5′-untranslated region of the mRNA for eIF4G, a factor involved in the picornavirus-induced switch from cap-dependent to internal initiation
    • W. Gan, and R. Rhoads Internal initiation of translation directed by the 5′-untranslated region of the mRNA for eIF4G, a factor involved in the picornavirus-induced switch from cap-dependent to internal initiation J. Biol. Chem. 271 1996 623 626
    • (1996) J. Biol. Chem. , vol.271 , pp. 623-626
    • Gan, W.1    Rhoads, R.2
  • 71
    • 0029437960 scopus 로고
    • Internal initiation of translation in eukaryotes: the picornavirus paradigm and beyond
    • R. Jackson, and A. Kaminski Internal initiation of translation in eukaryotes: the picornavirus paradigm and beyond RNA 1 1995 985 1000
    • (1995) RNA , vol.1 , pp. 985-1000
    • Jackson, R.1    Kaminski, A.2
  • 72
    • 0028961591 scopus 로고
    • Internal ribosome entry sites and dicistronic RNAs in mammalian transgenesis
    • P. Mountford, and A. Smith Internal ribosome entry sites and dicistronic RNAs in mammalian transgenesis Trends Genet. 11 1995 179 184
    • (1995) Trends Genet. , vol.11 , pp. 179-184
    • Mountford, P.1    Smith, A.2
  • 73
    • 0026753191 scopus 로고
    • Construction of a bifunctional mRNA in the mouse by using the internal ribosomal entry site of the encephalomyocarditis virus
    • D.G. Kim, H.M. Kang, S.K. Jang, and H.S. Shin Construction of a bifunctional mRNA in the mouse by using the internal ribosomal entry site of the encephalomyocarditis virus Mol. Cell. Biol. 12 1992 3636 3643
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3636-3643
    • Kim, D.G.1    Kang, H.M.2    Jang, S.K.3    Shin, H.S.4
  • 77
    • 0032572734 scopus 로고    scopus 로고
    • Generation of purified neural precursors from embryonic stem cells by lineage selection
    • M. Li, L. Pevny, R. Lovell-Badge, and A. Smith Generation of purified neural precursors from embryonic stem cells by lineage selection Curr. Biol. 8 1998 971 974
    • (1998) Curr. Biol. , vol.8 , pp. 971-974
    • Li, M.1    Pevny, L.2    Lovell-Badge, R.3    Smith, A.4
  • 79
    • 0035799309 scopus 로고    scopus 로고
    • Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells
    • R. Eiges, M. Schuldiner, M. Drukker, O. Yanuka, J. Itskovitz-Eldor, and N. Benvenisty Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells Curr. Biol. 11 2001 514 518
    • (2001) Curr. Biol. , vol.11 , pp. 514-518
    • Eiges, R.1    Schuldiner, M.2    Drukker, M.3    Yanuka, O.4    Itskovitz-Eldor, J.5    Benvenisty, N.6
  • 80
    • 0032488041 scopus 로고    scopus 로고
    • Cell therapy: in search of pluripotency
    • A. Smith Cell therapy: in search of pluripotency Curr. Biol. 8 1998 R802 R804
    • (1998) Curr. Biol. , vol.8
    • Smith, A.1
  • 81
    • 0032560802 scopus 로고    scopus 로고
    • Dolly is a clone-and no longer alone
    • D. Solter Dolly is a clone-and no longer alone Nature 394 1998 315 316
    • (1998) Nature , vol.394 , pp. 315-316
    • Solter, D.1
  • 82
    • 0032764950 scopus 로고    scopus 로고
    • Prospects for the use of nuclear transfer in human transplantation
    • P. Lanza, J. Cibelli, and M. West Prospects for the use of nuclear transfer in human transplantation Nat. Biotechnol. 17 1999 1171 1174
    • (1999) Nat. Biotechnol. , vol.17 , pp. 1171-1174
    • Lanza, P.1    Cibelli, J.2    West, M.3
  • 83
    • 0033145775 scopus 로고    scopus 로고
    • Nuclear transfer in farm animal species
    • K. Campbell Nuclear transfer in farm animal species Semin. Cell Dev. Biol. 10 1999 245 252
    • (1999) Semin. Cell Dev. Biol. , vol.10 , pp. 245-252
    • Campbell, K.1
  • 84
    • 0031044215 scopus 로고    scopus 로고
    • Viable offspring derived from fetal and adult mammalian cells
    • I. Wilmut, A.E. Schnieke, J. McWhir, A.J. Kind, and K.H. Campbell Viable offspring derived from fetal and adult mammalian cells Nature 385 1997 810 813
    • (1997) Nature , vol.385 , pp. 810-813
    • Wilmut, I.1    Schnieke, A.E.2    McWhir, J.3    Kind, A.J.4    Campbell, K.H.5
  • 85
    • 0032560827 scopus 로고    scopus 로고
    • Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei
    • T. Wakayama, A. Perry, A. Zuccotti, M. Johnson, and R.R. Yanagimachi Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei Nature 394 1998 369 374
    • (1998) Nature , vol.394 , pp. 369-374
    • Wakayama, T.1    Perry, A.2    Zuccotti, A.3    Johnson, M.4    Yanagimachi, R.R.5
  • 86
    • 0032993431 scopus 로고    scopus 로고
    • Cloning of male mice from adult tail-tip cells
    • T. Wakayama, and R. Yanagimachi Cloning of male mice from adult tail-tip cells Nat. Genet. 22 1999 127 128
    • (1999) Nat. Genet. , vol.22 , pp. 127-128
    • Wakayama, T.1    Yanagimachi, R.2
  • 89
    • 0034710596 scopus 로고    scopus 로고
    • Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei
    • M. Munsie, A. Michalska, C. O'Brien, A. Trounson, M. Pera, and P. Mountford Isolation of pluripotent embryonic stem cells from reprogrammed adult mouse somatic cell nuclei Curr. Biol. 10 2000 989 992
    • (2000) Curr. Biol. , vol.10 , pp. 989-992
    • Munsie, M.1    Michalska, A.2    O'Brien, C.3    Trounson, A.4    Pera, M.5    Mountford, P.6
  • 90
    • 0034486674 scopus 로고    scopus 로고
    • Mouse embryonic stem (ES) cell lines established from neuronal cell-derived cloned blastocysts
    • E. Kawase, Y. Yamazaki, T. Yagi, R. Yanagimachi, and R. Pedersen Mouse embryonic stem (ES) cell lines established from neuronal cell-derived cloned blastocysts Genesis 28 2000 156 163
    • (2000) Genesis , vol.28 , pp. 156-163
    • Kawase, E.1    Yamazaki, Y.2    Yagi, T.3    Yanagimachi, R.4    Pedersen, R.5
  • 91
    • 0035957754 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer
    • T. Wakayama, V. Tabar, I. Rodriguez, A. Perry, L. Studer, and P. Mombaerts Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer Science 292 2001 740 743
    • (2001) Science , vol.292 , pp. 740-743
    • Wakayama, T.1    Tabar, V.2    Rodriguez, I.3    Perry, A.4    Studer, L.5    Mombaerts, P.6
  • 95
    • 0037023568 scopus 로고    scopus 로고
    • Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy
    • W.M. Rideout III, K. Hochedlinger, M. Kyba, G.Q. Daley, and R. Jaenisch Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy Cell 109 2002 17 27
    • (2002) Cell , vol.109 , pp. 17-27
    • Rideout III, W.M.1    Hochedlinger, K.2    Kyba, M.3    Daley, G.Q.4    Jaenisch, R.5
  • 96
    • 19944376116 scopus 로고    scopus 로고
    • Electrical and neurotransmitter activity of mature neurons derived from mouse embryonic stem cells by Sox-1 lineage selection and directed differentiation
    • R.J. Lang, J.M. Haynes, J. Kelly, J. Johnson, J. Greenhalgh, C. O'Brien, E.M. Mulholland, L. Baker, M. Munsie, and C.W. Pouton Electrical and neurotransmitter activity of mature neurons derived from mouse embryonic stem cells by Sox-1 lineage selection and directed differentiation Eur. J. Neurosci. 20 2004 3209 3221
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 3209-3221
    • Lang, R.J.1    Haynes, J.M.2    Kelly, J.3    Johnson, J.4    Greenhalgh, J.5    O'Brien, C.6    Mulholland, E.M.7    Baker, L.8    Munsie, M.9    Pouton, C.W.10
  • 98
    • 0028787590 scopus 로고
    • Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons
    • C. Strübing, G. Ahnert-Hilger, J. Shan, B. Wiedenmann, J. Hescheler, and A. Wobus Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons Mech. Dev. 53 1995 275 287
    • (1995) Mech. Dev. , vol.53 , pp. 275-287
    • Strübing, C.1    Ahnert-Hilger, G.2    Shan, J.3    Wiedenmann, B.4    Hescheler, J.5    Wobus, A.6
  • 99
    • 0030931108 scopus 로고    scopus 로고
    • Hemato-lymphoid in vivo reconstitution potential of subpopulations derived from in vitro differentiated embryonic stem cells
    • A. Potocnik, H. Kohler, and K. Eichmann Hemato-lymphoid in vivo reconstitution potential of subpopulations derived from in vitro differentiated embryonic stem cells Proc. Natl. Acad. Sci. U. S. A. 94 1997 10295 10300
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 10295-10300
    • Potocnik, A.1    Kohler, H.2    Eichmann, K.3
  • 100
    • 18444407829 scopus 로고    scopus 로고
    • Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid
    • S. Shi, L. Hou, F. Tang, W. Jiang, P. Wang, M. Ding, and H. Deng Inducing embryonic stem cells to differentiate into pancreatic beta cells by a novel three-step approach with activin A and all-trans retinoic acid Stem Cells 23 2005 656 662
    • (2005) Stem Cells , vol.23 , pp. 656-662
    • Shi, S.1    Hou, L.2    Tang, F.3    Jiang, W.4    Wang, P.5    Ding, M.6    Deng, H.7
  • 101
    • 0032745067 scopus 로고    scopus 로고
    • Embryotoxicity screening using embryonic stem cells in vitro: correlation to in vivo teratogenicity
    • G. Scholz, I. Pohl, E. Genschow, M. Klemm, and H. Spielmann Embryotoxicity screening using embryonic stem cells in vitro: correlation to in vivo teratogenicity Cells Tissues Organs 165 1999 203 211
    • (1999) Cells Tissues Organs , vol.165 , pp. 203-211
    • Scholz, G.1    Pohl, I.2    Genschow, E.3    Klemm, M.4    Spielmann, H.5
  • 103
    • 0029443882 scopus 로고
    • Hitchcock's experimental series of foetal implants for Parkinson's disease: co-grafting ventral mesencephalon and striatum
    • C. Meyer, A. Detta, and C.C. Kudoh Hitchcock's experimental series of foetal implants for Parkinson's disease: co-grafting ventral mesencephalon and striatum Acta Neurochir., Suppl. 64 1995 1 4
    • (1995) Acta Neurochir., Suppl. , vol.64 , pp. 1-4
    • Meyer, C.1    Detta, A.2    Kudoh, C.C.3
  • 104
    • 0038700553 scopus 로고    scopus 로고
    • Selective ablation of human embryonic stem cells expressing a "suicide" gene
    • M. Schuldiner, J. Itskovitz-Eldor, and N. Benvenisty Selective ablation of human embryonic stem cells expressing a "suicide" gene Stem Cells 21 2003 257 265
    • (2003) Stem Cells , vol.21 , pp. 257-265
    • Schuldiner, M.1    Itskovitz-Eldor, J.2    Benvenisty, N.3


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