Generation of purified neural precursors from embryonic stem cells by lineage selection

Current Biology

Volumn 8, Issue 17, 1998, Pages 971-974

  Li, Meng ^a   Pevny, Larysa ^b   Lovell Badge, Robin ^b   Smith, Austin ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOGENETICS; GENETIC MANIPULATION; STEM CELL; STEM CELL TRANSPLANTATION;

EID: 0032572734     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(98)70399-9     Document Type: Article

References (23)

1. Brook FA, Gardner RL: The origin and efficient derivation of embryonic stem cells in the mouse. Proc Natl Acad Sci USA 1997, 94:5709-5712.
2. Evans MJ, Kaufman M: Establishment in culture of pluripotential cells from mouse embryos. Nature 1981, 292:154-156.
3. Martin GR: Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 1981, 78:7634-7638.
4. Bain G, Kitchens D, Yao M, Huettner JE, Gottlieb DI: Embryonic stem cells express neuronal properties in vitro. Dev Biol 1995, 168:342-357.
5. Okabe S, Forsberg-Nilsson K, Spiro AC, Segal M, McKay RDG: Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro. Mech Dev 1996, 59:89-102.
6. Fraichard A, Chassande O, Bilbaut G, Dehay C, Savatier P, Samarut J: In vitro differentiation of embryonic stem cells into glial cells and functional neurons. J Cell Sci 1995, 108:3181-3188.
7. Strubing C, Ahnert-Hilger G, Shan J, Wiedenmann B, Hescheler J, Wobus AM: Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons. Mech Dev 1995, 53:275-287.
8. Robertson EJ: Teratocarcinoma and Embryo-derived Stem Cells: a Practical Approach. Oxford: IRL Press; 1987.
9. Lendahl U, Zimmerman LB, McKay RDG: CNS stem cells express a new class of intermediate filament protein. Cell 1990, 60:585-595.
10. Sejersen T, Lendahl U: Transient expression of nestin during skeletal muscle development. J Cell Sci 1993, 106:1291-1300.
11. Pevny LH, Sockanathan S, Placzek M, Lovell-Badge R: A role for Sox1 in neural determination. Development 1998, 125:1967-1978.
12. Collignon J: Study of a New Family of Genes Related to the Mammalian Testis Determining Gene. PhD Thesis, Council for National Academy Awards, London; 1992.
13. Liem KF, Tremmi G, Roelink H, Jessell TM: Dorsal differentiation of neural plate cells by BMP-mediated signals from epidermal ectoderm. Cell 1995, 82:969-979.
14. Walther C, Gruss P: Pax-6, a murine paired box gene, is expressed in the developing CNS. Development 1991, 113:1435-1449.
15. Tanabe Y, Jessell TM: Diversity and pattern in the developing spinal cord. Science 1996, 274:1115-1123.
16. Gradwohl G, Fode C, Guillemot F: Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors. Dev Biol 1996, 180:227-241.
17. Henrique D, Adam J, Myat A, Chitnis A, Lewis J, Ish-Horowicz D: Expression of a Delta homologue in prospective neurons in the chick. Nature 1995, 375:787-790.
18. Ericson J, Thor S, Edlund T, Jessell TM, Yamada T: Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1. Science 1992, 256:1550-1560.
19. Palmer TD, Takahashi J, Gage FH: The adult hippocampus contains primordial stem cells. Mol Cell Neurosci 1997, 8:389-404.
20. McKay R: Stem cells in the central nervous system. Science 1997, 276:66-71.
21. Klug MG, Soonpaa MH, Koh GY, Field LJ: Genetically selected cardiomyocytes from differentiating embryonic stem cells form stable intracardiac grafts. J Clin Invest 1996, 98:216-224.
22. Brustle O, Spiro AC, Karram K, Choudhary K, Okabe S, McKay RD: In vitro-generated neural precursors participate in mammalian brain development. Proc Natl Acad Sci USA 1997, 94:14809-14814.
23. Deacon T, Dinsmore J, Costantini LC, Ratliff J, Isacson O: Blastula-stage stem cells can differentiate into dopaminergic and serotonergic neurons after transplantation. Exp Neurol 1998, 149:28-41.