Direct activation of the apoptosis machinery as a mechanism to target cancer cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 13, 2003, Pages 7533-7538

  Nguyen, Jack T ^a   Wells, James A ^a  

^a Sunesis Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; CYTOTOXIC AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN P53;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CELL FREE SYSTEM; CONTROLLED STUDY; CYTOSTASIS; DRUG CYTOTOXICITY; DRUG TARGETING; ENZYME LINKED IMMUNOSORBENT ASSAY; HELA CELL; HUMAN; HUMAN CELL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; CASPASE 3; CASPASES; CELL-FREE SYSTEM; CHROMATOGRAPHY, GEL; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HELA CELLS; HUMANS; MODELS, BIOLOGICAL; NEOPLASMS; PROTEIN BINDING; PROTEINS; RNA, SMALL INTERFERING; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0038610951     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1031631100     Document Type: Article

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