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Volumn 60, Issue 10, 2003, Pages 2272-2278

Expression of membrane and nuclear melatonin receptor mRNA and protein in the mouse immune system

Author keywords

Immune system; Melatonin membrane receptor; Melatonin nuclear receptor; mRNA expression; Protein expression; Spleen; Thymus

Indexed keywords

1 (3 ALLYL 4 OXOTHIAZOLIDIN 2 YLIDENE) 4 METHYLTHIOSEMICARBAZONE; AGOMELATINE; CELL NUCLEUS RECEPTOR; MELATONIN RECEPTOR; MEMBRANE RECEPTOR; MESSENGER RNA; NEUROHORMONE; PROTEIN; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0242320500     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-003-3207-4     Document Type: Article
Times cited : (129)

References (56)
  • 1
    • 0037379998 scopus 로고    scopus 로고
    • Role of melatonin in the regulation of human circadian rhythms and sleep
    • Cajochen C., Krauchi K. and Wirz-Justice A. (2003) Role of melatonin in the regulation of human circadian rhythms and sleep. J. Neuroendocrinol. 15: 432-437
    • (2003) J. Neuroendocrinol. , vol.15 , pp. 432-437
    • Cajochen, C.1    Krauchi, K.2    Wirz-Justice, A.3
  • 2
    • 0034901997 scopus 로고    scopus 로고
    • Biology of mammalian photoperiodism and the critical role of the pineal gland and melatonin
    • Malpaux B., Migaud M., Tricoire H. and Chemineau P. (2001) Biology of mammalian photoperiodism and the critical role of the pineal gland and melatonin. J. Biol. Rhythms 16: 336-347
    • (2001) J. Biol. Rhythms , vol.16 , pp. 336-347
    • Malpaux, B.1    Migaud, M.2    Tricoire, H.3    Chemineau, P.4
  • 3
    • 0025758136 scopus 로고
    • Pineal melatonin: Cell biology of its synthesis and of its physiological interactions
    • Reiter R. J. (1991) Pineal melatonin: cell biology of its synthesis and of its physiological interactions. Endocr. Rev. 12: 151-180
    • (1991) Endocr. Rev. , vol.12 , pp. 151-180
    • Reiter, R.J.1
  • 4
    • 0031845040 scopus 로고    scopus 로고
    • Oxidative damage in the central nervous system: Protection by melatonin
    • Reiter R. J. (1998) Oxidative damage in the central nervous system: protection by melatonin. Prog. Neurobiol. 56: 359-384
    • (1998) Prog. Neurobiol. , vol.56 , pp. 359-384
    • Reiter, R.J.1
  • 5
    • 0032188888 scopus 로고    scopus 로고
    • Influence of melatonin on invasive and metastatic properties of MCF-7 human breast cancer cells
    • Cos S., Fernandez R., Guezmes A. and Sánchez-Barcelo E. J. (1998) Influence of melatonin on invasive and metastatic properties of MCF-7 human breast cancer cells. Cancer Res. 58: 4383-4390
    • (1998) Cancer Res. , vol.58 , pp. 4383-4390
    • Cos, S.1    Fernandez, R.2    Guezmes, A.3    Sánchez-Barcelo, E.J.4
  • 6
    • 0026830761 scopus 로고
    • The ageing pineal gland and its physiological consequences
    • Reiter R. J. (1992) The ageing pineal gland and its physiological consequences. Bioessays 14: 169-175
    • (1992) Bioessays , vol.14 , pp. 169-175
    • Reiter, R.J.1
  • 7
  • 9
    • 0036925663 scopus 로고    scopus 로고
    • Possible involvement of the nuclear RZR/ROR-alpha receptor in the antitumor action of melatonin on murine Colon 38 cancer
    • Winczyk K., Pawlikowski M., Guerrero J. M. and Karasek M. (2002) Possible involvement of the nuclear RZR/ROR-alpha receptor in the antitumor action of melatonin on murine Colon 38 cancer. Tumour Biol. 23: 298-302
    • (2002) Tumour Biol. , vol.23 , pp. 298-302
    • Winczyk, K.1    Pawlikowski, M.2    Guerrero, J.M.3    Karasek, M.4
  • 10
    • 0034986704 scopus 로고    scopus 로고
    • Melatonin activates PKC-alpha but not PKC-epsilon in N1E-115 cells
    • Benitez-King G., Hernandez M. E., Tovar R. and Ramirez G. (2001) Melatonin activates PKC-alpha but not PKC-epsilon in N1E-115 cells. Neurochem. Int. 39: 95-102
    • (2001) Neurochem. Int. , vol.39 , pp. 95-102
    • Benitez-King, G.1    Hernandez, M.E.2    Tovar, R.3    Ramirez, G.4
  • 11
    • 0036482282 scopus 로고    scopus 로고
    • Chemical and physical properties and potential mechanisms: Melatonin as a broad spectrum antioxidant and free radical scavenger
    • Tan D. X., Reiter R. J., Manchester L. C., Yan M. T., El-Sawi M., Sainz R. M. et al. (2002) Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr. Top. Med. Chem. 2: 181-197
    • (2002) Curr. Top. Med. Chem. , vol.2 , pp. 181-197
    • Tan, D.X.1    Reiter, R.J.2    Manchester, L.C.3    Yan, M.T.4    El-Sawi, M.5    Sainz, R.M.6
  • 12
    • 0034283784 scopus 로고    scopus 로고
    • Cytokines and hormones as possible links between endocrinosenescence and immunosenescence
    • Straub R. H., Miller L. E., Scholmerich J. and Zietz B. (2000) Cytokines and hormones as possible links between endocrinosenescence and immunosenescence. J. Neuroimmunol. 109: 10-15
    • (2000) J. Neuroimmunol. , vol.109 , pp. 10-15
    • Straub, R.H.1    Miller, L.E.2    Scholmerich, J.3    Zietz, B.4
  • 13
    • 0033664956 scopus 로고    scopus 로고
    • Melatonin mediates seasonal changes in immune function
    • Nelson R. J. and Drazen D. L. (2000) Melatonin mediates seasonal changes in immune function. Ann. N. Y. Acad. Sci. 917: 404-415
    • (2000) Ann. N. Y. Acad. Sci. , vol.917 , pp. 404-415
    • Nelson, R.J.1    Drazen, D.L.2
  • 14
    • 0018747092 scopus 로고
    • Circadian rhythm in activity of lympholytic natural killer cells from spleens of Fischer rats
    • Fernandes G., Carandente F., Halberg E., Halberg F. and Good R. A. (1979) Circadian rhythm in activity of lympholytic natural killer cells from spleens of Fischer rats. J. Immunol. 123: 622-625
    • (1979) J. Immunol. , vol.123 , pp. 622-625
    • Fernandes, G.1    Carandente, F.2    Halberg, E.3    Halberg, F.4    Good, R.A.5
  • 15
    • 0031154476 scopus 로고    scopus 로고
    • Diurnal rhythmicity of human cytokine production: A dynamic disequilibrium in T helper cell type 1/T helper cell type 2 balance?
    • Petrovsky N. and Harrison L. C. (1997) Diurnal rhythmicity of human cytokine production: a dynamic disequilibrium in T helper cell type 1/T helper cell type 2 balance? J. Immunol. 158: 5163-5168
    • (1997) J. Immunol. , vol.158 , pp. 5163-5168
    • Petrovsky, N.1    Harrison, L.C.2
  • 16
    • 0027510439 scopus 로고
    • Neonatal pinealectomy impairs murine antibody-dependent cellular cytotoxicity
    • Vermeulen M., Palermo M. and Giordano M. (1993) Neonatal pinealectomy impairs murine antibody-dependent cellular cytotoxicity. J. Neuroimmunol. 43: 97-101
    • (1993) J. Neuroimmunol. , vol.43 , pp. 97-101
    • Vermeulen, M.1    Palermo, M.2    Giordano, M.3
  • 18
    • 0033953569 scopus 로고    scopus 로고
    • Melatonin is responsible for the nocturnal increase observed in serum and thymus of thymosin alpha1 and thymulin concentrations: Observations in rats and humans
    • Molinero P., Soutto M., Benot S., Hmadcha A. and Guerrero J. M. (2000) Melatonin is responsible for the nocturnal increase observed in serum and thymus of thymosin alpha1 and thymulin concentrations: observations in rats and humans. J. Neuroimmunol. 103: 180-188
    • (2000) J. Neuroimmunol. , vol.103 , pp. 180-188
    • Molinero, P.1    Soutto, M.2    Benot, S.3    Hmadcha, A.4    Guerrero, J.M.5
  • 19
    • 0032085641 scopus 로고    scopus 로고
    • Exogenous melatonin enhances cell-mediated, but not humoral, immune function in adult male deer mice (Peromyscus maniculatus)
    • Demas G. E. and Nelson R. J. (1998) Exogenous melatonin enhances cell-mediated, but not humoral, immune function in adult male deer mice (Peromyscus maniculatus). J. Biol. Rhythms 13: 245-252
    • (1998) J. Biol. Rhythms , vol.13 , pp. 245-252
    • Demas, G.E.1    Nelson, R.J.2
  • 21
    • 0031570820 scopus 로고    scopus 로고
    • Melatonin enhances IL-2, IL-6, and IFN-gamma production by human circulating CD4+ cells: A possible nuclear receptor-mediated mechanism involving T helper type 1 lymphocytes and monocytes
    • Garcia-Mauriño S., Gonzalez-Haba M. G., Calvo J. R., Rafii-El-Idrissi M., Sanchez-Margalet V., Goberna R. et al. (1997) Melatonin enhances IL-2, IL-6, and IFN-gamma production by human circulating CD4+ cells: a possible nuclear receptor-mediated mechanism involving T helper type 1 lymphocytes and monocytes. J. Immunol. 159: 574-581
    • (1997) J. Immunol. , vol.159 , pp. 574-581
    • Garcia-Mauriño, S.1    Gonzalez-Haba, M.G.2    Calvo, J.R.3    Rafii-El-Idrissi, M.4    Sanchez-Margalet, V.5    Goberna, R.6
  • 24
    • 0032829442 scopus 로고    scopus 로고
    • Identification of highly elevated levels of melatonin in bone marrow: Its origin and significance
    • Tan D. X., Manchester L. C., Reiter R. J., Qi W. B., Zhang M., Weintraub S. T. et al. (1999) Identification of highly elevated levels of melatonin in bone marrow: its origin and significance. Biochim. Biophys. Acta 1472: 206-214
    • (1999) Biochim. Biophys. Acta , vol.1472 , pp. 206-214
    • Tan, D.X.1    Manchester, L.C.2    Reiter, R.J.3    Qi, W.B.4    Zhang, M.5    Weintraub, S.T.6
  • 25
    • 0027337438 scopus 로고
    • 125I]iodomelatonin-binding sites in the bursa of Fabricius of birds: Binding characteristics, subcellular distribution, diurnal variations and age studies
    • 125I]iodomelatonin-binding sites in the bursa of Fabricius of birds: binding characteristics, subcellular distribution, diurnal variations and age studies. J. Endocrinol. 138: 51-57
    • (1993) J. Endocrinol. , vol.138 , pp. 51-57
    • Liu, Z.M.1    Pang, S.F.2
  • 26
    • 0028959537 scopus 로고
    • Specific binding of 2-[125I]iodomelatonin by rat splenocytes: Characterization and its role on regulation of cyclic AMP production
    • Rafii-El-Idrissi M., Calvo J. R., Pozo D., Harmouch A. and Guerrero J. M. (1995) Specific binding of 2-[125I]iodomelatonin by rat splenocytes: characterization and its role on regulation of cyclic AMP production. J. Neuroimmunol. 57: 171-178
    • (1995) J. Neuroimmunol. , vol.57 , pp. 171-178
    • Rafii-El-Idrissi, M.1    Calvo, J.R.2    Pozo, D.3    Harmouch, A.4    Guerrero, J.M.5
  • 28
    • 0028018966 scopus 로고
    • Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses
    • Reppert S. M., Weaver D. R. and Ebisawa T. (1994) Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 13: 1177-1185
    • (1994) Neuron , vol.13 , pp. 1177-1185
    • Reppert, S.M.1    Weaver, D.R.2    Ebisawa, T.3
  • 29
    • 0029115639 scopus 로고
    • Molecular characterization of a second melatonin receptor expressed in human retina and brain: The Mellb melatonin receptor
    • Reppert S. M., Godson C., Mahle C. D., Weaver D. R., Slaugenhaupt S. A. and Gusella J. F. (1995) Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mellb melatonin receptor. Proc. Natl. Acad. Sci. USA 92: 8734-8738
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8734-8738
    • Reppert, S.M.1    Godson, C.2    Mahle, C.D.3    Weaver, D.R.4    Slaugenhaupt, S.A.5    Gusella, J.F.6
  • 30
    • 0034613342 scopus 로고    scopus 로고
    • Identification of the melatonin-binding site MT3 as the quinone reductase 2
    • Nosjean O., Ferro M., Coge F., Beauverger P., Henlin J. M., Lefoulon F et al. (2000) Identification of the melatonin-binding site MT3 as the quinone reductase 2. J. Biol. Chem. 275: 31311-31317
    • (2000) J. Biol. Chem. , vol.275 , pp. 31311-31317
    • Nosjean, O.1    Ferro, M.2    Coge, F.3    Beauverger, P.4    Henlin, J.M.5    Lefoulon, F.6
  • 31
    • 0035221189 scopus 로고    scopus 로고
    • Nuclear melatonin receptors
    • Mosc
    • Smirnov A. N. (2001) Nuclear melatonin receptors. Biochemistry (Mosc) 66: 19-26
    • (2001) Biochemistry , vol.66 , pp. 19-26
    • Smirnov, A.N.1
  • 32
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P. and Sacchi N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 33
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 34
    • 0034254930 scopus 로고    scopus 로고
    • In vitro and in vivo evidence for orphan nuclear receptor RORa1pha function in bone metabolism
    • Meyer T., Kneissel M., Mariani J. and Fournier B. (2000) In vitro and in vivo evidence for orphan nuclear receptor RORa1pha function in bone metabolism. Proc. Natl. Acad. Sci. USA 97: 9197-9202
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9197-9202
    • Meyer, T.1    Kneissel, M.2    Mariani, J.3    Fournier, B.4
  • 35
    • 0025833853 scopus 로고
    • Melatonin-induced enhancement of antibody-dependent cellular cytotoxicity
    • Giordano M. and Palermo M. S. (1991) Melatonin-induced enhancement of antibody-dependent cellular cytotoxicity. J. Pineal Res. 10: 117-121
    • (1991) J. Pineal Res. , vol.10 , pp. 117-121
    • Giordano, M.1    Palermo, M.S.2
  • 37
    • 0034696884 scopus 로고    scopus 로고
    • Melatonin reversal of lipopolysacharides-induced thermal and behavioral hyperalgesia in mice
    • Raghavendra V., Agrewala J. N. and Kulkarni S. K. (2000) Melatonin reversal of lipopolysacharides-induced thermal and behavioral hyperalgesia in mice. Eur. J. Pharmacol. 395: 15-21
    • (2000) Eur. J. Pharmacol. , vol.395 , pp. 15-21
    • Raghavendra, V.1    Agrewala, J.N.2    Kulkarni, S.K.3
  • 38
    • 0033859912 scopus 로고    scopus 로고
    • Melatonin inhibits apoptosis during early B-cell development in mouse bone marrow
    • Yu Q., Miller S. C. and Osmond D. G. (2000) Melatonin inhibits apoptosis during early B-cell development in mouse bone marrow. J. Pineal Res. 29: 86-93
    • (2000) J. Pineal Res. , vol.29 , pp. 86-93
    • Yu, Q.1    Miller, S.C.2    Osmond, D.G.3
  • 39
    • 0034896128 scopus 로고    scopus 로고
    • Pineal indoles stimulate the gene expression of immunomodulating cytokines
    • Liu F., Ng T. B. and Fung M. C. (2001) Pineal indoles stimulate the gene expression of immunomodulating cytokines. J. Neural Transm. 108: 397-405
    • (2001) J. Neural Transm. , vol.108 , pp. 397-405
    • Liu, F.1    Ng, T.B.2    Fung, M.C.3
  • 40
    • 0034813281 scopus 로고    scopus 로고
    • Rejuvenation of degenerative thymus by oral melatonin administration and the antagonistic action of melatonin against hydroxyl radical-induced apoptosis of cultured thymocytes in mice
    • Tian Y. M., Li P. P., Jiang X. F., Zhang G. Y. and Dai Y. R. (2001) Rejuvenation of degenerative thymus by oral melatonin administration and the antagonistic action of melatonin against hydroxyl radical-induced apoptosis of cultured thymocytes in mice. J. Pineal Res. 31: 214-221
    • (2001) J. Pineal Res. , vol.31 , pp. 214-221
    • Tian, Y.M.1    Li, P.P.2    Jiang, X.F.3    Zhang, G.Y.4    Dai, Y.R.5
  • 41
    • 0027952777 scopus 로고
    • Pineal control of aging: Effect of melatonin and pineal grafting on aging mice
    • Pierpaoli W, and Regelson W. (1994) Pineal control of aging: effect of melatonin and pineal grafting on aging mice. Proc. Natl. Acad. Sci. USA 91: 787-791
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 787-791
    • Pierpaoli, W.1    Regelson, W.2
  • 42
    • 0032527635 scopus 로고    scopus 로고
    • Melatonin: Immune modulation of spleen cells in young, middle-aged and senescent mice
    • Atre D. and Blumenthal E. J. (1998) Melatonin: immune modulation of spleen cells in young, middle-aged and senescent mice. Mech. Ageing Dev. 103: 255-268
    • (1998) Mech. Ageing Dev. , vol.103 , pp. 255-268
    • Atre, D.1    Blumenthal, E.J.2
  • 43
    • 58149320608 scopus 로고
    • 125I] iodomelatonin binding sites in the thymus of mice and its significance
    • 125I] iodomelatonin binding sites in the thymus of mice and its significance. Sci. China. B. 38: 1455-1461
    • (1995) Sci. China. B , vol.38 , pp. 1455-1461
    • Liu, Z.1    Zhao, Y.2    Peng, S.3
  • 44
    • 0025922228 scopus 로고
    • 125I]iodomelatonin binding sites in spleens of birds and mammals
    • 125I] iodomelatonin binding sites in spleens of birds and mammals. Neurosci. Lett. 125: 175-178
    • (1991) Neurosci. Lett. , vol.125 , pp. 175-178
    • Yu, Z.H.1    Yuan, H.2    Lu, Y.3    Pang, S.F.4
  • 45
    • 0029893687 scopus 로고    scopus 로고
    • Structure, characterization, and expression of the gene encoding the mouse Mella melatonin receptor
    • Roca A. L., Godson C., Weaver D. R. and Reppert S. M. (1996) Structure, characterization, and expression of the gene encoding the mouse Mella melatonin receptor. Endocrinology 137: 3469-3477
    • (1996) Endocrinology , vol.137 , pp. 3469-3477
    • Roca, A.L.1    Godson, C.2    Weaver, D.R.3    Reppert, S.M.4
  • 48
    • 0036257935 scopus 로고    scopus 로고
    • Expression of melatonin MT(1) and MT(2) receptors, and ROR alpha(1) receptor in transplantable murine Colon 38 cancer
    • Karasek M., Carrillo-Vico A., Guerrero J. M., Winczyk K. and Pawlikowski M. (2003) Expression of melatonin MT(1) and MT(2) receptors, and ROR alpha(1) receptor in transplantable murine Colon 38 cancer. Neuroendocrinol. Lett. 23: 55-60
    • (2003) Neuroendocrinol. Lett. , vol.23 , pp. 55-60
    • Karasek, M.1    Carrillo-Vico, A.2    Guerrero, J.M.3    Winczyk, K.4    Pawlikowski, M.5
  • 49
    • 0032585722 scopus 로고    scopus 로고
    • RORgammaT, a thymus-specific isoform of the orphan nuclear receptor RORgamma/TOR, is up-regulated by signaling through the pre-T cell receptor and binds to the TEa promoter
    • Villey I., Chasseval R. de and Villartay J. P. de (1999) RORgammaT, a thymus-specific isoform of the orphan nuclear receptor RORgamma/TOR, is up-regulated by signaling through the pre-T cell receptor and binds to the TEA promoter. Eur. J. Immunol. 29: 4072-4080
    • (1999) Eur. J. Immunol. , vol.29 , pp. 4072-4080
    • Villey, I.1    De Chasseval, R.2    De Villartay, J.P.3
  • 50
    • 0032161469 scopus 로고    scopus 로고
    • Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms
    • Dubocovich M. L., Yun K., Al Ghoul W. M., Benloucif S. and Masana M. I. (1998) Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms. FASEB J. 12: 1211-1220
    • (1998) FASEB J. , vol.12 , pp. 1211-1220
    • Dubocovich, M.L.1    Yun, K.2    Al Ghoul, W.M.3    Benloucif, S.4    Masana, M.I.5
  • 51
    • 0036369441 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor: A critical neurohumoral mediator
    • Petrovsky N. and Bucala R. (2002) Macrophage migration inhibitory factor: a critical neurohumoral mediator. Front. Horm. Res. 29: 83-90
    • (2002) Front. Horm. Res. , vol.29 , pp. 83-90
    • Petrovsky, N.1    Bucala, R.2
  • 52
    • 0034877393 scopus 로고    scopus 로고
    • Melatonin receptor subtype MT2 (Mel 1b) and not mt1 (Mel 1a) is associated with melatonin-induced enhancement of cell-mediated and humoral immunity
    • Drazen D. L. and Nelson R. J. (2001) Melatonin receptor subtype MT2 (Mel 1b) and not mt1 (Mel 1a) is associated with melatonin-induced enhancement of cell-mediated and humoral immunity. Neuroendocrinology 74: 178-184
    • (2001) Neuroendocrinology , vol.74 , pp. 178-184
    • Drazen, D.L.1    Nelson, R.J.2
  • 53
    • 0035026369 scopus 로고    scopus 로고
    • Melatonin enhancement of splenocyte proliferation is attenuated by luzindole, a melatonin receptor antagonist
    • Drazen D. L., Bilu D., Bilbo S. D. and Nelson R. J. (2001) Melatonin enhancement of splenocyte proliferation is attenuated by luzindole, a melatonin receptor antagonist. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280: 1476-1482
    • (2001) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.280 , pp. 1476-1482
    • Drazen, D.L.1    Bilu, D.2    Bilbo, S.D.3    Nelson, R.J.4
  • 54
    • 0030867140 scopus 로고    scopus 로고
    • Luzindole, a melatonin receptor antagonist, suppresses experimental autoimmune encephalomyelitis
    • Constantinescu C. S., Milliard B., Ventura E. and Rostami A. (1997) Luzindole, a melatonin receptor antagonist, suppresses experimental autoimmune encephalomyelitis. Pathobiology 65: 190-194
    • (1997) Pathobiology , vol.65 , pp. 190-194
    • Constantinescu, C.S.1    Milliard, B.2    Ventura, E.3    Rostami, A.4
  • 55
    • 0033626587 scopus 로고    scopus 로고
    • Potential involvement of mtl receptor and attenuated sex steroid-induced calcium influx in the direct anti-proliferative action of melatonin on androgen-responsive LNCaP human prostate cancer cells
    • Xi S. C., Tam P. C., Brown G. M., Pang S. F. and Shiu S. Y. (2000) Potential involvement of mtl receptor and attenuated sex steroid-induced calcium influx in the direct anti-proliferative action of melatonin on androgen-responsive LNCaP human prostate cancer cells. J. Pineal Res. 29: 172-183
    • (2000) J. Pineal Res. , vol.29 , pp. 172-183
    • Xi, S.C.1    Tam, P.C.2    Brown, G.M.3    Pang, S.F.4    Shiu, S.Y.5
  • 56
    • 0034894104 scopus 로고    scopus 로고
    • Melatonin and RZR/ROR receptor ligand CGP 52608 induce apoptosis in the murine colonic cancer
    • Winczyk K., Pawlikowski M. and Karasek M. (2001) Melatonin and RZR/ROR receptor ligand CGP 52608 induce apoptosis in the murine colonic cancer. J. Pineal Res. 31: 179-182
    • (2001) J. Pineal Res. , vol.31 , pp. 179-182
    • Winczyk, K.1    Pawlikowski, M.2    Karasek, M.3


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