Environmental regulation of flowering

International Journal of Developmental Biology

Volumn 49, Issue 5-6, 2005, Pages 689-705

  Ausín, Israel ^a   Alonso Blanco, Carlos ^a   Martínez Zapater, José Miguel ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

Flowering time; Light quality; Natural variation; Photoperiod; Vernalization

Indexed keywords

ARABIDOPSIS; ENVIRONMENTAL FACTOR; FLC GENE; FLOWERING; GENE; GENE SEQUENCE; LIGHT; NONHUMAN; PHOTOPERIODICITY; PHOTORECEPTOR; PLANT DEVELOPMENT; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; TEMPERATURE; VERNALIZATION;

ARABIDOPSIS; ENVIRONMENT; FLOWERS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, PLANT; GENES, PLANT; MODELS, BIOLOGICAL; PHOTOBIOLOGY; PHOTOPERIOD; PHOTOSYNTHETIC REACTION CENTER COMPLEX PROTEINS; PLANTS; TEMPERATURE;

ARABIDOPSIS;

EID: 27744446105     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: 10.1387/ijdb.052022ia     Document Type: Review

References (165)

1. ADAMS, J., KELSO, R. and COOLEY, L. (2000). The kelch repeat superfamily of proteins: propellers of cell function. Trends Cell. Biol. 10: 17-24.
2. AHMAD, M. and CASHMORE, A.R. (1993). HY4 gene of Arabidopsis thaliana encodes a protein with characteristics of a blue-light photoreceptor. Nature. 366: 162-166.
3. AHMAD, M., JARILLO, J.A., SMIRNOVA, O. and CASHMORE, A.R. (1998). The CRY1 blue light photoreceptor of Arabidopsis interacts with phytochrome A in vitro. Mol. Cell. 1: 939-948.
4. ALABADI, D., OYAMA, T., YANOVSKY, M.J., HARMON, F.G., MAS, P. and KAY, S.A. (2001). Reciprocal regulation between TOC1 and LHY/CCA1 within the Arabidopsis circadian clock. Science. 293: 880-883.
5. AUKERMAN, M.J., HIRSCHFELD, M., WESTER, L., WEAVER, M., CLACK, T., AMASINO, R.M. and SHARROCK, R.A. (1997). A deletion in the PHYD gene of the Arabidopsis Wassilewskija ecotype defines a role for phytochrome D in red/far-red light sensing. Plant Cell. 9: 1317-1326.
6. AUSIN, I., ALONSO-BLANCO, C., JARILLO, J.A., RUIZ-GARCIA, L. and MARTINEZ-ZAPATER, J.M. (2004). Regulation of flowering time by FVE, a retinoblastoma-associated protein. Nat. Genet. 36: 162-166
7. BALLARE C.L. (1999). Keeping up with the neighbours: phytochrome sensing and other signalling mechanisms. Trends Plant Sci. 4: 201.
8. BASTOW, R., MYLNE, J.S., LISTER, C., LIPPMAN, Z., MARTIENSSEN, R.A. and DEAN, C. (2004). Vernalization requires epigenetic silencing of FLC by histone methylation. Nature. 427: 164-167.
9. BAUER, D., VICZIAN, A., KIRCHER, S., NOBIS, T., NITSCHKE, R., KUNKEL, T., PANIGRAHI, K.C., ADAM, E., FEJES, E., SCHAFER, E. and NAGY, F. (2004). Constitutive photomorphogenesis 1 and multiple photoreceptors control degradation of phytochrome interacting factor 3: a transcription factor required for light signaling in Arabidopsis. Plant Cell. 16: 1433-1445
10. BERNIER, G. and PÉRILLEUX, C. (2005) A physiological overview of the genetics of flowering time control. Plant Biotech. J. 31: 3-16
11. BIRD, A. (2002). DNA methylation and epigenetic memory. Genes Dev. 16: 6-21.
12. BLAZQUEZ, M.A. and WEIGEL, D. (2000). Integration of floral inductive signals in Arabidopsis. Nature. 404: 889-892.
13. BLAZQUEZ, M.A., TRENOR, M. and WEIGEL, D. (2002). Independent control of gibberellin biosynthesis and flowering time by the circadian clock in Arabidopsis. Plant Physiol. 130: 1770-1775.
14. BLAZQUEZ, M.A., AHN, J.H. and WEIGEL, D. (2003). A thermosensory pathway controlling flowering time in Arabidopsis thaliana. Nat. Genet. 33: 168-171.
15. BOSS, P.K., BASTOW, R.M., MYLNE, J.S. and DEAN, C. (2004). Multiple pathways in the decision to flower: enabling, promoting and resetting. Plant Cell. 16: S18-31.
16. BÜNNING, E. (1936) Die endogene Tagesrhthmik als Grundlage der photoperiodischen Reaktion. Ber. Dtsch. Bot. Ges. 54: 590-607
17. CERDAN, P.D. and CHORY, J. (2003). Regulation of flowering time by light quality. Nature. 423: 881-885.
18. CHANDLER, J., WILSON, A. and DEAN, C. (1996). Arabidopsis mutants showing an altered response to vernalization. Plant J. 10: 637-644.
19. CHOUARD, P. (1960) Vernalization and its relations to dormancy. Annu. Rev. Plant Physiol. 11: 191-238.
20. CLARKE, J.H., Y DEAN, C. (1994). Mapping FRI, a locus controlling flowering time and vernalization response in Arabidopsis thaliana. Mol. Gen. Genet. 242: 81-8
21. DEVLIN, P.F. and KAY, S.A. (2000). Cryptochromes are required for phytochrome signaling to the circadian clock but not for rhythmicity. Plant Cell. 12: 2499-2510.
22. DEVLIN, P.F., PATEL, S.R. and WHITELAM, G.G. (1998). Phytochrome E influences internode elongation and flowering time in Arabidopsis. Plant Cell. 10: 1479-1487.
23. DEVLIN, P.F., ROBSON, P.R.H., PATEL, S.R., GOOSEY, L., SHARROCK, R.A. and WHITELAM, G.C. (1999). Phytochrome D acts in the shade-avoidance syndrome in Arabidopsis by controlling elongation growth and flowering time. Plant Physiol. 119: 909-915.
24. DOI, K., IZAWA, T., FUSE, T., YAMANOUCHI, U., KUBO, T., SHIMATANI, Z., YANO, M. and YOSHIMURA, A. (2004). Ehd1: a B-type response regulator in rice, confers short-day promotion of flowering and controls FT-like gene expression independently of Hd1. Genes Dev. 18: 926-936
25. DOYLE, M.R., DAVIS, S.J., BASTOW, R.M., MCWATTERS, H.G., KOZMABOGNAR, L., NAGY, F., MILLAR, A.J. and AMASINO, R.M. (2002). The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana. Nature. 419: 74-77.
26. EL-ASSAL, EL-DIN S., ALONSO-BLANCO, C., PEETERS, A.J., RAZ, V. and KOORNNEEF, M. (2001). A QTL for flowering time in Arabidopsis reveals a novel allele of CRY2. Nat. Genet. 29: 435-440.
27. ENNOS, A. (1999). The aerodynamics and hydrodynamics of plants. J. Exp. Biol. 202: 3281-3284.
28. FINNEGAN, E.J., PEACOCK, W.J. and DENNIS, E.S. (1996). Reduced DNA methylation in Arabidopsis thaliana results in abnormal plant development. Proc. Natl. Acad. Sci. USA. 93: 8449-8454.
29. FINNEGAN, E.J., SHELDON, C.C., JARDINAUD, F., PEACOCK, W.J. and DENNIS, E.S. (2004). A cluster of Arabidopsis genes with a coordinate response to an environmental stimulus. Curr. Biol. 14: 911-916.
30. FOWLER, S., LEE, K., ONOUCHI, H., SAMACH, A., RICHARDSON, K., MORRIS, B., COUPLAND, G. and PUTTERILL, J. (1999). GIGANTEA: a circadian clock-controlled gene that regulates photoperiodic flowering in Arabidopsis and encodes a protein with several possible membrane-spanning domains. EMBO J. 18: 4679-4688.
31. GENGER, R.K., PEACOCK, W.J., DENNIS, E.S. and FINNEGAN, E.J. (2003). Opposing effects of reduced DNA methylation on flowering time in Arabidopsis thaliana. Planta. 216: 461-466.
32. GENDALL, A.R., LEVY, Y.Y., WILSON, A. and DEAN, C. (2001). The VERNALIZATION 2 gene mediates the epigenetic regulation of vernalization in Arabidopsis. Cell. 107: 525-535.
33. GOTO, N., KUMAGAI, T. and KOORNNEEF, M. (1991). Flowering responses to light-breaks in photomorphogenic mutants of Arabidopsis thaliana, a long-day plant. Physiol. Plantarum. 83: 209-215
34. GUO, H., DUONG, H., MA, N. and LIN, C. (1999). The Arabidopsis blue light receptor cryptochrome 2 is a nuclear protein regulated by a blue light-dependent post-transcriptional mechanism. Plant J. 19: 279-287.
35. GUO, L.P., ZHANG, F.S., WANG, X.R., MAO, D.R. and CHEN, X.P. (2001). Effect of long-term fertilization on soil nitrate distribution. J. Environ. Sci. (China.) 13: 58-63.
36. HALL, A., BASTOW, R.M., DAVIS, S.J., HANANO, S., MCWATTERS, H.G., HIBBERD, V., DOYLE, M.R., SUNG, S., HALLIDAY, K.J., AMASINO, R.M. and MILLAR, A.J. (2003). The TIME FOR COFFEE gene maintains the amplitude and timing of Arabidopsis circadian clocks. Plant Cell. 15: 2719-2729.
37. HALLIDAY, K.J., SALTER, M.G., THINGNAES, E. and WHITELAM, G.C. (2003). Phytochrome control of flowering is temperature sensitive and correlates with expression of the floral integrator FT. Plant J. 33: 875-885.
38. HALLIDAY, K.J., KOORNNEEF, M. and WHITELAM, G.C. (1994). Phytochrome B and at least one other phytochrome mediate the accelerated flowering response of Arabidopsis thaliana L. to low red/far-red ratio. Plant Physiol. 104: 1311-1315.
39. HALLIDAY, K.J. and WHITELAM, G.C. (2003). Changes in photoperiod ortemperature alter the functional relationships between phytochromes and reveal roles for phyD and phyE. Plant Physiol. 131: 1913-1920.
40. HANUMAPPA, M., PRATT, L.H., CORDONNIER-PRATT, M.M. and DEITZER, G.F. (1999). A photoperiod-insensitive barley line contains a light-labile phytochrome B. Plant Physiol. 119: 1033-1040.
41. HARMER, S.L., HOGENESCH, J.B., STRAUME, M., CHANG, H.-S., HAN, B., ZHU, T., WANG, X., KREPS, J.A. and KAY, S.A. (2000). Orchestrated transcription of key pathways in Arabidopsis by the circadian clock. Science. 290: 2110-2113.
42. HAYAMA, R., YOKOI, S., TAMAKI, S., YANO, M. and SHIMAMOTO, K. (2003). Adaptation of photoperiodic control pathways produces short-day flowering in rice. Nature. 422: 719-722.
43. HE, Y., MICHAELS, S.D. and AMASINO, R.M. (2003). Regulation of flowering time by histone acetylation in Arabidopsis. Science. 302: 1751-1754.
44. HE, Y., DOYLE, M.R. and AMASINO, R.M. (2004a). PAF1-complex-mediated histone methylation of FLOWERING LOCUS C chromatin is required for the vernalization-responsive, winter-annual habit in Arabidopsis. Genes Dev. 18: 2774-2784.
45. HE, Y. and AMASINO, R.M. (2005). Role of chromatin modification in flowering-time control. Trends Plant. Sci. 10: 30-35
46. HE, Y., TANG, R.-H., HAO, Y., STEVENS, R.D., COOK, C.W., AHN, S.M., JING, L., YANG, Z., CHEN, L., GUO, F., FIORANI, F., JACKSON, R.B., CRAWFORD, N.M. and PEI, Z.-M. (2004b). Nitric oxide represses the Arabidopsis floral transition. Science. 305: 1968-1971.
47. HELLMANN, H. and ESTELLE, M. (2002). Regulation by Protein Degradation. Science. 297: 793-797.
48. HENDERSON, I.R., SHINDO, C. and DEAN, C. (2003). The need for the winter in the switch to flowering. Ann. Rev. Genet. 37: 371-392
49. HEPWORTH, S.R., VALVERDE, F., RAVENSCROFT, D., MOURADOV, A. and COUPLAND, G. (2002). Antagonistic regulation of flowering-time gene SOC1 by CONSTANS and FLC via separate promoter motifs. EMBO J. 21: 4327-4337.
50. HUQ, E., TEPPERMAN, J.M. and QUAIL, P.H. (2000). GIGANTEA is a nuclear protein involved in phytochrome signaling in Arabidopsis. Proc. Natl. Acad. Sci. USA. 97: 11673-11673
51. IMAIZUMI, T., TRAN, H.G., SWARTZ, T.E., BRIGGS, W.R. and KAY, S.A. (2003). FKF1 is essential for photoperiodic-specific light signalling in Arabidopsis. Nature. 426: 302-306
52. IZAWA, T., OIKAWA, T., SUGIYAMA, N., TANISAKA, T., YANO, M. and SHIMAMOTO, K. (2002). Phytochrome mediates the external light signal to repress FT orthologues in photoperiodic flowering of rice. Genes Dev. 16: 2006-2020.
53. JACKSON, J.P., LINDROTH, A.M., CAO, X. and JACOBSEN, S.E. (2002). Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature. 416: 556-560.
54. JARILLO, J.A., CAPEL, J., TANG, R.H., YANG, H.Q., ALONSO, J.M., ECKER, J.R. and CASHMORE, A.R. (2001). An Arabidopsis circadian clock component interacts with both CRY1 and PHYB. Nature. 410: 487-490.
55. JOHANSON, U., WEST, J., LISTER, C., MICHAELS, S., AMASINO, R. and DEAN, C. (2000). Molecular analysis of FRIGIDA, a major determinant of natural variation in Arabidopsis flowering time. Science. 290: 344-347.
56. JOHNSON, E., BRADLEY, M., HARBERD, N.P. and WHITELAM, G.C. (1994). Photoresponses of Light-Grown phyA Mutants of Arabidopsis Phytochrome A Is Required for the Perception of Daylength Extensions. Plant Physiol. 105: 141-149.
57. JOHNSON, K.A., SISTRUNK, M.L., POLISENSKY, D.H. and BRAAM, J. (1998). Arabidopsis thaliana responses to mechanical stimulation do not require ETR1 or EIN2. Plant Physiol. 116: 643-649.
58. KARDAILSKY, I., SHUKLA, V.K., AHN, J.H., DAGENAIS, N., CHRISTENSEN, S.K., NGUYEN, J.T., CHORY, J., HARRISON, M.J. and WEIGEL, D. (1999). Activation tagging of the floral inducer FT. Science. 286: 1962-1965.
59. KIM, H.J., HYUN, Y., PARK, J.Y., PARK, M.J., PARK, M.K., KIM, M.D., LEE, M.H., MOON, J., LEE, I. and KIM, J. (2004). A genetic link between cold responses and flowering time through FVE in Arabidopsis thaliana. Nat. Genet. 36: 167-171.
60. KIM, W.-Y., GENG, R. and SOMERS, D.E. (2003). Circadian phase-specific degradation of the F-box protein ZTL is mediated by the proteasome. Proc. Natl. Acad. Sci. USA. 100: 4933-4938.
61. KIPREOS, E.T. and PAGANO, M. (2000). The F-box protein family. Genome Biol. 1: 30021-7.
62. KIRCHER, S., KOZMA-BOGNAR, L., KIM, L., ADAM, E., HARTER, K., SCHAFER, E. and NAGY, F. (1999). Light quality-dependent nuclear import of the plant photoreceptors phytochrome A and B. Plant Cell. 11: 1445-1456.
63. KIRCHER, S., GIL, P., KOZMA-BOGNAR, L., FEJES, E., SPETH, V., HUSSELSTEIN-MULLER, T., BAUER, D., ADAM, E., SCHAFER, E. and NAGY, F. (2002). Nucleocytoplasmic partitioning of the plant photoreceptors phytochrome A, B, C, D and E is regulated differentially by light and exhibits a diurnal rhythm. Plant Cell. 14: 1541-1555.
64. KLEINER, O., KIRCHER, S., HARTER, K. and BATSCHAUER, A. (1999). Nuclear localization of the Arabidopsis blue light receptor cryptochrome 2. Plant J. 19: 289-296.
65. KNIGHT MR, CAMPBELL AK, SMITH SM and TREWAVAS AJ. (1991) Transgenic plant aequorin reports the effects of touch and cold-shock and elicitors on cytoplasmic calcium Nature. 8;352(6335):524-6
66. KOBAYASHI, Y., KAYA, H., GOTO, K., IWABUCHI, M. and ARAKI, T. (1999). A pair of related genes with antagonistic roles in mediating flowering signals. Science. 286: 1960-1962.
67. KOJIMA, S., TAKAHASHI, Y., KOBAYASHI, Y., MONNA, L., SASAKI, T., ARAKI, T. and YANO, M. (2002). Hd3a, a rice ortholog of the Arabidopsis FT gene, promotes transition to flowering downstream of Hd1 under short-day conditions. Plant Cell Physiol 43: 1096-1105.
68. KOORNNEEF, M., HANHART, C.J. and VAN DER VEEN, J.H. (1991). A genetic and physiological analysis of late flowering mutants in Arabidopsis thaliana. Mol. Gen. Genet. 229: 57-66.
69. KOORNNEEF, M., BLANKESTIJN DE VRIES, C. J. HANHART, W. SOPPE and A. J. M. PEETERS. (1994) The phenotype of some late-flowering mutants is enhanced by a locus on chromosome 5 that is not effective in the Landsberg erecta wild-type. Plant J. 6: 911-919
70. KROGAN, N.J., DOVER, J., WOOD, A., SCHNEIDER, J., HEIDT, J., BOATENG, M.A., DEAN, K., RYAN, O.W., GOLSHANI, A., JOHNSTON, M., GREENBLATT, J.F. and SHILATIFARD, A. (2003). The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol. Cell. 11: 721-729.
71. KUZMICHEV, A., ZHANG, Y., ERDJUMENT-BROMAGE, H., TEMPST, P. and REINBERG, D. (2002). Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1). Mol. Cell. Biol. 22: 835-848.
72. LAMATTINA, L., GARCIA-MATA, C., GRAZIANO, M. and PAGNUSSAT, G. (2003). Nitric oxide: the versatility of an extensive signal molecule. Annu. Rev. Plant. Biol. 54: 109-136.
73. LANG, A. (1965). Physiology of flower initiation. Encyclopaedia of Plant Physiology. Vol 15: W. Rhuland, ed. (Springer- Verlag, Berlin), 1380-1536
74. LANGRIDGE, J. (1957). Effect of day-length and gibberellic acid on the flowering of Arabidopsis. Nature. 180: 36-37.
75. LEDGER, S., STRAYER, C., ASHTON, F., KAY, S.A. and PUTTERILL, J. (2001). Analysis of the function of two circadian-regulated CONSTANS-LIKE genes. Plant J. 26: 15-22
76. LEE, I., BLEECKER, A. and AMASINO, R. (1993). Analysis of naturally occurring late flowering in Arabidopsis thaliana. Mol. Gen. Genet. 237: 171-176
77. LEE, I., AUKERMAN, M.J., GORE, S.L., LOHMAN, K.N., MICHAELS, S.D., WEAVER, L.M., JOHN, M.C., FELDMANN, K.A. and AMASINO, R.M. (1994). Isolation of LUMINIDEPENDENS: a gene involved in the control of flowering time in Arabidopsis. Plant Cell. 6: 75-83
78. LEVY, Y.Y., MESNAGE, S., MYLNE, J.S., GENDALL, A.R. and DEAN, C. (2002). Multiple roles of Arabidopsis VRN1 in vernalization and flowering time control. Science. 297: 243-246
79. LIM, M.H., KIM, J., KIM, Y.S., CHUNG, K.S., SEO, Y.H., LEE, I., HONG, C.B., KIM, H.J. and PARK, C.M. (2004). A new Arabidopsis gene, FLK, encodes an RNA binding protein with K homology motifs and regulates flowering time via FLOWERING LOCUS C. Plant Cell. 16: 731-740
80. LIN, C. (2000). Plant blue-light receptors. Trends. Plant. Sci. 5: 337-342.
81. LIN, C., YANG, H., GUO, H., MOCKLER, T., CHEN, J. and CASHMORE, A.R. (1998). Enhancement of blue-light sensitivity of Arabidopsis seedlings by a blue light receptor cryptochrome 2. Proc. Natl. Acad. Sci. USA. 95: 2686-2690.
82. LIU, J., HE, Y., AMASINO, R. and CHEN, X. (2004). siRNAs targeting an intronic transposon in the regulation of natural flowering behavior in Arabidopsis. Genes Dev. 18: 2873-2878.
83. LIU, X.L., COVINGTON, M.F., FANKHAUSER, C., CHORY, J. and WAGNER, D.R. (2001). ELF3 encodes a circadian clock-regulated nuclear protein that functions in an Arabidopsis PHYB signal transduction pathway. Plant Cell. 13: 1293-1304.
84. MACKNIGHT, R., BANCROFT, I., PAGE, T., LISTER, C., SCHMIDT, R., LOVE, K., WESTPHAL, L., MURPHY, G., SHERSON, S., COBBETT, C. and DEAN, C. (1997). FCA, a gene controlling flowering time in Arabidopsis, encodes a protein containing RNA-binding domains. Cell. 89: 737-745
85. MARTINEZ, C., PONS, E., PRATS, G. and LEON, J. (2004). Salicylic acid regulates flowering time and links defence responses and reproductive development. Plant J. 37: 209-217.
86. MARTINEZ-GARCIA, J.F., HUQ, E. and QUAIL, P.H. (2000). Direct targeting of light signals to a promoter element-bound transcription factor. Science. 288: 859-863.
87. MARTINEZ-ZAPATER, J.M. and SOMERVILLE, C.R. (1990). Effect of light quality and vernalization on late flowering mutants of Arabidopsis thaliana. Plant Physiol. 92: 770-776
88. MAS, P., DEVLIN, P.F., PANDA, S. and KAY, S.A. (2000). Functional interaction of phytochrome B and cryptochrome 2. Nature. 408: 207-211.
89. MCKAY, J.K., RICHARDS, J.H. and MITCHELL-OLDS, T. (2003). Genetics of drought adaptation in Arabidopsis thaliana: I. Pleiotropy contributes to genetic correlations among ecological traits. Mol. Ecol. 12: 1137-1151.
90. MICHAELS, S.D. and AMASINO, R.M. (1999). FLOWERING LOCUS C encodes a novel MADS domain protein that acts as a repressor of flowering. Plant Cell. 11: 949-956.
91. MICHAELS, S.D. and AMASINO, R.M. (2001). Loss of FLOWERING LOCUS C activity eliminates the late-flowering phenotype of FRIGIDA and autonomous pathway mutations but not responsiveness to vernalization. Plant Cell. 13: 935-941.
92. MICHAELS, S.D., BEZERRA, I.C. and AMASINO, R.M. (2004). FRIGIDA-related genes are required for the winter-annual habit in Arabidopsis. Proc. Natl. Acad. Sci. USA 101: 3281-3285.
93. MICHAELS, S.D., HE, Y.H., SCORTECCI, K.C. and AMASINO, R.M. (2003). Attenuation of FLOWERING LOCUS C activity as a mechanism for the evolution of summer-annual flowering behavior in Arabidopsis. Proc. Natl. Acad. Sci. USA 100: 10102-10107.
94. MIZOGUCHI, T., WHEATLEY, K., HANZAWA, Y., WRIGHT, L., MIZOGUCHI, M., SONG, H.R., CARRE, I.A. and COUPLAND, G. (2002). LHy and CCA1 are partially redundant genes required to maintain circadian rhythms in Arabidopsis. Dev. Cell. 2: 629-641.
95. MOCKLER, T., YANG, H., YU, X., PARIKH, D., CHENG, Y.C., DOLAN, S. and LIN, C. (2003). Regulation of photoperiodic flowering by Arabidopsis photoreceptors. Proc. Natl. Acad. Sci USA. 100: 2140-2145.
96. MOCKLER, T.C., YU, X., SHALITIN, D., PARIKH, D., MICHAEL, T.P., LIOU, J., HUANG, J., SMITH, Z., ALONSO, J.M., ECKER, J.R., CHORY, J. and LIN, C. (2004). Regulation of flowering time in Arabidopsis by K homology domain proteins. Proc. Natl. Acad. Sci. USA. 101: 12759-12764.
97. MONTE, E., ALONSO, J.M., ECKER, J.R., ZHANG, Y., LI, X., YOUNG, J., AUSTIN-PHILLIPS, S. and QUAIL, P.H. (2003). Isolation and characterization of phyC mutants in Arabidopsis reveals complex crosstalk between phytochrome signaling pathways. Plant Cell. 15: 1962-1980.
98. MOON, J., LEE, H., KIM, M. and LEE, I. (2005). Analysis of flowering pathway integrators in Arabidopsis. Plant Cell Physiol. 024.
99. MOON, J., SUH, S.S., LEE, H., CHOI, K.R., HONG, C.B., PAEK, N.C., KIM, S.G. and LEE, I. (2003). The SOC1MADS-box gene integrates vernalization and gibberellin signals for flowering in Arabidopsis. Plant J. 35: 613-623.
100. MOURADOV, A., CREMER, F. and COUPLAND, G. (2002). Control of flowering time: interacting pathways as a basis for diversity. Plant Cell. 14 Suppl: S111-130.
101. NAPP-ZINN, K. (1987). Vernalization environmental and epigenetic regulation. Manipulation of flowering. EdJ.G.Atherton. 123-132
102. NELSON, D.C., LASSWELL, J., ROGG, L.E., COHEN, M.A. and BARTEL, B. (2000). FKF1: a clock-controlled gene that regulates the transition to flowering in Arabidopsis. Cell. 101: 331-340.
103. NG, H.H., DOLE, S. and STRUHL, K. (2003). The Rtf1 component of the Paf1 transcriptional elongation complex is required for ubiquitination of histone H2B. J. Biol. Chem. 278: 33625-33628.
104. NI, M., TEPPERMAN, J.M. and QUAIL, P.H. (1999). Binding of phytochrome B to its nuclear signalling partner PIF3 is reversibly induced by light. Nature. 400: 781-784.
105. NOH, Y.S. and AMASINO, R.M. (2003). PIE1: an ISWI family gene, is required for FLC activation and floral repression in Arabidopsis. Plant Cell. 15: 1671-1682.
106. OH, S., ZHANG, H., LUDWIG, P. and VAN NOCKER, S. (2004). A mechanism related to the yeast transcriptional regulator Paf1c is required for expression of the Arabidopsis FLC/MAF MADS box gene family. Plant Cell. 16: 2940-2953.
107. ONOUCHI, H., IGENO, M.I., PERILLEUX, C., GRAVES, K. and COUPLAND, G. (2000). Mutagenesis of plants overexpressing CONSTANS demonstrates novel interactions among Arabidopsis flowering-time genes. Plant Cell. 12: 885-900.
108. PARK, D.H., SOMERS, D.E., KIM, Y.S., CHOY, Y.H., LIM, H.K., SOH, M.S., KIM, H.J., KAY, S.A. and NAM, H.G. (1999). Control of circadian rhythms and photoperiodic flowering by the Arabidopsis GIGANTEA gene. Science. 285: 1579-1582.
109. PIGLIUCCI, M. and KOLODYNSKA, A. (2002). Phenotypic plasticity and integration in response to flooded conditions in natural accessions of Arabidopsis thaliana (L.) Heynh (Brassicaceae). Ann. Bot. (Lond). 90: 199-207.
110. PIGLIUCCI, M., WHITTON, J. and SCHLICHTING, C.D. (1995). Reaction norms of Arabidopsis. I. Plasticity of characters and correlations across water, nutrient and light gradients. J. Evol. Biol. 8: 421-438.
111. PITTENDRIGH, C.S. (1960). Circadian rhythms and the circadian organization of living systems. Cold Spring Harb. Symp. Quant. Biol. 25: 159-184.
112. PLIETH, C., HANSEN, U.P., KNIGHT, H. and KNIGHT, M.R. (1999). Temperature sensing by plants: the primary characteristics of signal perception and calcium response. Plant J. 18: 491-497.
113. PUTTERILL, J., ROBSON, F., LEE, K., SIMON, R. and COUPLAND, G. (1995). The CONSTANS gene of Arabidopsis promotes flowering and encodes a protein showing similarities to zinc finger transcription factors. Cell. 80: 847-857.
114. PUTTERILL, J., LAURIE, R. and MACKNIGHT, R. (2004). It's time to flower: the genetic control of flowering time. Bioessays. 26: 363-373.
115. QUAIL, P.H. (2002). Photosensory perception and signalling in plant cells: new paradigms?. Curr. Op. Cell Biol. 14: 180-188.
116. QUESADA, V., MACKNIGHT, R., DEAN, C. and SIMPSON, G.G. (2003). Autoregulation of FCA pre-mRNA processing controls Arabidopsis flowering time. EMBO J. 22: 3142-3152.
117. QIAN, Y.W. and LEE, E.Y. (1995). Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast. J. Biol. Chem. 270: 25507-25513.
118. RATCLIFFE, O.J., NADZAN, G.C., REUBER, T.L. and RIECHMANN, J.L. (2001). Regulation of flowering in Arabidopsis by an FLC homologue. Plant Physiol. 126: 122-132.
119. RATCLIFFE, O.J., KUMIMOTO, R.W., WONG, B.J. and RIECHMANN, J.L. (2003). Analysis of the Arabidopsis MADS AFFECTING FLOWERING gene family: MAF2 prevents vernalization by short periods of cold. Plant Cell. 15: 1159-1169.
120. REED, J.W., NAGATANI, A., ELICH, T.D., FAGAN, M. and CHORY, J. (1994). Phytochrome A and phytochrome B have overlapping but distinct functions in Arabidopsis development. Plant Physiol. 104: 1139-1149.
121. REDEI, G.P. (1962). Supervital mutants in Arabidopsis. Genetics. 47: 443-460
122. RIDGWAY, P. and ALMOUZNI, G. (2000). CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair. J. Cell. Sci. 113: 2647-2658.
123. RONEMUS, M.J., GALBIATI, M., TICKNOR, C., CHEN, J. and DELLAPORTA, S.L. (1996). Demethylation-induced developmental pleiotropy in Arabidopsis. Science. 273: 654-657.
124. ROSSI, V., LOCATELLI, S., LANZANOVA, C., BONIOTTI, M.B., VAROTTO, S., PIPAL, A., GORALIK-SCHRAMEL, M., LUSSER, A., GATZ, C., GUTIERREZ, C. and MOTTO, M. (2003). A maize histone deacetylase and retinoblastoma-related protein physically interact and cooperate in repressing gene transcription. Plant Mol. Biol. 51: 401-413.
125. ROUSE, D.T., SHELDON, C.C., BAGNALL, D.J., PEACOCK, W.J. and DENNIS, E.S. (2002). FLC, a repressor of flowering, is regulated by genes in different inductive pathways. Plant J. 29: 183-191.
126. SALOME, P.A. and MCCLUNG, C.R. (2004). The Arabidopsis thaliana Clock. J. Biol. Rhythms. 19: 425-435.
127. SALOME, P.A. and MCCLUNG, C.R. (2005). PSEUDO-RESPONSE REGULATOR 7 and 9 are partially redundant genes essential for the temperature responsiveness of the Arabidopsis circadian clock. Plant Cell. 17: 791-803.
128. SAMACH, A., ONOUCHI, H., GOLD, S.E., DITTA, G.S., SCHWARZ-SOMMER, Z., YANOFSKY, M.F. and COUPLAND, G. (2000). Distinct roles of CONSTANS target genes in reproductive development of Arabidopsis. Science. 288: 1613-1616
129. SANDA, S.L. and AMASINO, R.M. (1996). Interaction of FLC and late-flowering mutations in Arabidopsis thaliana. Mol. Gen. Genet. 251: 69-74.
130. SANTOS-ROSA, H., SCHNEIDER, R., BANNISTER, A.J., SHERRIFF, J., BERNSTEIN, B.E., EMRE, N.C., SCHREIBER, S.L., MELLOR, J. and KOUZARIDES, T. (2002). Active genes are tri-methylated at K4 of histone H3. Nature. 419: 407-411
131. SCHAFFER, R., RAMSAY, N., SAMACH, A., CORDEN, S., PUTTERILL, J., CARRE, I.A. and COUPLAND, G. (1998). The late elongated hypocotyl mutation of Arabidopsis disrupts circadian rhythms and the photoperiodic control of flowering. Cell. 93: 1219-1229.
132. SCHOMBURG, F.M., PATTON, D.A., MEINKE, D.W. and AMASINO, R.M. (2001) FPA, a gene involved in floral induction in Arabidopsis, encodes a protein containing RNA-recognition motifs. Plant Cell. 13: 1427-1436.
133. SCHRANZ, M.E., QUIJADA, P., SUNG, S.-B., LUKENS, L., AMASINO, R. and OSBORN, T.C. (2002). Characterization and effects of the replicated flowering time gene FLC in Brassica rapa. Genetics. 162: 1457-1468.
134. SCHULTZ, T.F., KIYOSUE, T., YANOVSKY, M., WADA, M. and KAY, S.A. (2001). A Role for LKP2 in the circadian clock of Arabidopsis. Plant Cell. 13: 2659-2670.
135. SCORTECCI, K.C., MICHAELS, S.D. and AMASINO, R.M. (2001). Identification of a MADS-box gene, FLOWERING LOCUS M, that represses flowering. Plant J. 26 229-236.
136. SHARROCK, R.A. and CLACK, T. (2002). Patterns of expression and normalized levels of the five Arabidopsis phytochromes. Plant Physiol. 130: 442-456.
137. SHELDON, C.C., CONN, A.B., DENNIS, E.S. and PEACOCK, W.J. (2002). Different regulatory regions are required for the vernalization-induced repression of FLOWERING LOCUS C and for the epigenetic maintenance of repression. Plant Cell. 14: 2527-2537.
138. SHELDON, C.C., ROUSE, D.T., FINNEGAN, E.J., PEACOCK, W.J. and DENNIS, E.S. (2000). The molecular basis of vernalization: the central role of FLOWERING LOCUS C (FLC). Proc Natl Acad Sci USA. 97: 3753-3758.
139. SIMPSON, G.G., DIJKWEL, P.P., QUESADA, V., HENDERSON, I. and DEAN, C. (2003). FY is an RNA 3′ end-processing factor that interacts with FCA to control the Arabidopsis floral transition. Cell. 113: 777-787.
140. SIMPSON, G.G. and DEAN, C. (2002). Arabidopsis, the Rosetta stone of flowering time? Science. 296: 285-289.
141. SOMERS, D.E., DEVLIN, P.P. and KAY, S.A. (1998). Phytochromes and cryptochromes in the entrainment of the Arabidopsis circadian clock. Science. 282: 1488-1490
142. SOMERS DE, SCHULTZ TF, MILNAMOW M and KAY SA. (2000). ZEITLUPE encodes a novel clock-associated PAS protein from Arabidopsis. Cell. 101(3): 319-29.
143. SOPPE, W.J.J., BENTSINK, L. and KOORNNEEF, M. (1999). The early-flowering mutant efs is involved in the autonomous promotion pathway of Arabidopsis thaliana. Development. 126: 4763-4770.
144. STRAYER, C., OYAMA, T., SCHULTZ, T.F., RAMAN, R., SOMERS, D.E., MAS, P., PANDA, S., KREPS, J.A. and KAY, S.A. (2000). Cloning of the Arabidopsis clock gene TOC1: an autoregulatory response regulator homolog. Science. 289: 768-771.
145. STRAYER, C.A. and KAY, S.A. (1999). The ins and outs of circadian regulated gene expression. Curr. Op. Plant Biol. 2: 114-120.
146. SUAREZ-LOPEZ, P., WHEATLEY, K., ROBSON, F., ONOUCHI, H., VALVERDE, F. and COUPLAND, G. (2001). CONSTANS mediates between the circadian clock and the control of flowering in Arabidopsis. Nature. 410: 1116-1120.
147. SUNG, S. and AMASINO, R.M. (2004). Vernalization in Arabidopsis thaliana is mediated by the PHD finger protein VIN3. Nature. 427: 159-164.
148. TAKAHASHI, Y., SHOMURA, A., SASAKI, T. and YANO, M. (2001). Hd6: a rice quantitative trait locus involved in photoperiod sensitivity, encodes the alpha subunit of protein kinase CK2. Proc. Natl. Acad. Sci. USA. 98: 7922-7927.
149. TRANQUILLI, G. and DUBCOVSKY, J. (2000). Epistatic interaction between vernalization genes Vrn-Am1 and Vrn-Am2 in diploid wheat. J. Hered. 91: 304-306.
150. TYLER, J.K., BULGER, M., KAMAKAKA, R.T., KOBAYASHI, R. and KADONAGA, J.T. (1996). The p55 subunit of Drosophila chromatin assembly factor 1 is homologous to a histone deacetylase-associated protein. Mol. Cell Biol. 16: 6149-6159.
151. VALVERDE, F., MOURADOV, A., SOPPE, W., RAVENSCROFT, D., SAMACH, A. and COUPLAND, G. (2004). Photoreceptor regulation of CONSTANS protein in photoperiodic flowering. Science. 303: 1003-1006.
152. WANG, Z.Y. and TOBIN, E.M. (1998). Constitutive expression of the CIRCADIAN CLOCK ASSOCIATED 1 (CCM) gene disrupts circadian rhythms and suppresses its own expression. Cell. 93: 1207-1217.
153. WELLENSIEK, S. J. (1962). Dividing cells as the locus for vernalization. Nature. 195: 307-308
154. WELLENSIEK S.J. (1964) Dividing cells as the prerequisite for vernalization. Plant Physiol. 39: 832-835
155. WELLER, J.L., BEAUCHAMP, N., KERCKHOFFS, L.H., PLATTEN, J.D. and REID, J.B. (2001). Interaction of phytochromes A and B in the control of de-etiolation and flowering in pea. Plant J. 26: 283-294.
156. WESTERMAN, J.M. and LAWRENCE, M.J. (1970). Genotype-environment interaction and developmental regulation in Arabidopsis thaliana inbred lines. Heredity. 25: 609-627.
157. WILSON R.N., HECKMAN J.W. and SOMERVILLE C.R. (1992). Gibberellin is required for flowering under short days. Plant Physiol. 100 (1): 403-408
158. YAN, L., LOUKOIANOV, A., TRANQUILLI, G., HELGUERA, M., FAHIMA, T. and DUBCOVSKY, J. (2003). Positional cloning of the wheat vernalization gene VRN1. Proc. Natl. Acad. Sci. USA. 100: 6263-6268.
159. YAN, L., LOUKOIANOV, A., BLECHL, A., TRANQUILLI, G., RAMAKRISHNA, W., SANMIGUEL, P., BENNETZEN, J.L., ECHENIQUE, V. and DUBCOVSKY, J. (2004). The wheat VRN2 gene is a flowering repressor down-regulated by vernalization. Science. 303: 1640-1644.
160. YANO, M., KATAYOSE, Y., ASHIKARI, M., YAMANOUCHI, U., MONNA, L., FUSE, T., BABA, T., YAMAMOTO, K., UMEHARA, Y., NAGAMURA, Y. and SASAKI, T. (2000). Hd1: a major photoperiod sensitivity quantitative trait locus in rice, is closely related to the Arabidopsis flowering time gene CONSTANS. Plant Cell. 12: 2473-2484.
161. YANOVSKY, M.J. and KAY, S.A. (2002). Molecular basis of seasonal time measurement in Arabidopsis. Nature. 419: 308-312.
162. YANOVSKY, M.J. and KAY, S.A. (2003). Living by the calendar: how plants know when to flower. Nat. Rev. Mol. Cell. Biol. 4: 265-276.
163. YANOVSKY, M.J., MAZZELLA, M.A. and CASAL, J.J. (2000). A quadruple photoreceptor mutant still keeps track of time. Curr. Biol. 10: 1013-1015.
164. ZHANG, H. and VAN NOCKER, S. (2002). The VERNALIZATION INDEPENDENCE 4 gene encodes a novel regulator of FLOWERING LOCUS C. Plant J. 31: 663-673.
165. ZHANG, H., RANSOM, C., LUDWIG, P. and VAN NOCKER, S. (2003). Genetic analysis of early flowering mutants in Arabidopsis defines a class of pleiotropic developmental regulator required for expression of the flowering-time switch FLOWERING LOCUS C. Genetics. 164: 347-358.