-
1
-
-
0032211830
-
The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease
-
D.J. Selkoe, The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease, Trends Cell Biol. 8 (1998), 447-453.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 447-453
-
-
Selkoe, D.J.1
-
2
-
-
0035194145
-
Evidence of oxidative damage in Alzheimer's disease brain: Central role for amyloid beta-peptide
-
(a) D. A. Butterfield, J. Drake, C. Pocemich and A. Castegna, Evidence of oxidative damage in Alzheimer's disease brain: Central role for amyloid beta-peptide, Trends Mol Med. 7 (2001), 548-554.
-
(2001)
Trends Mol. Med.
, vol.7
, pp. 548-554
-
-
Butterfield, D.A.1
Drake, J.2
Pocemich, C.3
Castegna, A.4
-
3
-
-
0033860372
-
Review: Alzheimer's beta-peptide-associated free radical oxidative stress and neurotoxicity
-
(b) S. Varadarajan, S. Yatin, M. Aksenova and D.A. Butterfield, Review: Alzheimer's beta-peptide-associated free radical oxidative stress and neurotoxicity, J. Struct. Biol. 130 (2000), 184-208.
-
(2000)
J. Struct. Biol.
, vol.130
, pp. 184-208
-
-
Varadarajan, S.1
Yatin, S.2
Aksenova, M.3
Butterfield, D.A.4
-
4
-
-
0030928406
-
β-amyloid-associated free radical oxidative stress and neurotoxicity: Implications for Alzheimer's disease
-
D.A. Butterfield, β-amyloid-associated free radical oxidative stress and neurotoxicity: Implications for Alzheimer's disease, Chem. Res. Toxicol. 10 (1997), 495-506.
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 495-506
-
-
Butterfield, D.A.1
-
5
-
-
0028172886
-
β-amyloid neurotoxicity requires fibril formation and is inhibited by Congo Red
-
A. Lorenzo and B.A. Yankner, β-amyloid neurotoxicity requires fibril formation and is inhibited by Congo Red, Proc. Natl. Acad. Sci. USA 91 (1994), 12243-12247.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
6
-
-
0032880901
-
Methionine residue 35 is in amyloid beta-peptide-associated free radical oxidative stress
-
S. Varadarajan, S. Yatin, J. Kanski, F. Jahanshahi and D.A. Butterfield, Methionine residue 35 is in amyloid beta-peptide-associated free radical oxidative stress, Brain Res. Bull. 50 (1999), 133-141.
-
(1999)
Brain Res. Bull.
, vol.50
, pp. 133-141
-
-
Varadarajan, S.1
Yatin, S.2
Kanski, J.3
Jahanshahi, F.4
Butterfield, D.A.5
-
7
-
-
0032696045
-
On methionine and Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress
-
S. Yatin, S. Varadarajan, C. Link and D.A. Butterfield, On methionine and Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress, Neurobiol. Aging 20 (1999), 339-342.
-
(1999)
Neurobiol. Aging
, vol.20
, pp. 339-342
-
-
Yatin, S.1
Varadarajan, S.2
Link, C.3
Butterfield, D.A.4
-
8
-
-
0034700471
-
AΒ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
C. Janus, J. Pearson, J. McLaurin, P.M. Matthews, Y. Jiang, S.D. Schmidt, M.A. Chishti, P. Home, D. Heslin, J. French, H.T.J. Mount, R.A. Nixon, M. Mercken, C. Bergeron, P.E. Fraser, P. St George-Hyslop and D. Westway, AΒ Peptide Immunization Reduces Behavioural Impairment and Plaques in a Model of Alzheimer's Disease, Nature 408 (2000), 979-982.
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Matthews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Chishti, M.A.7
Home, P.8
Heslin, D.9
French, J.10
Mount, H.T.J.11
Nixon, R.A.12
Mercken, M.13
Bergeron, C.14
Fraser, P.E.15
St George-Hyslop, P.16
Westway, D.17
-
9
-
-
0033844944
-
Characterization of copper interactions with Alzheimer amyloid beta peptides: Identification of an attomoler-affinity copper binding site on amyloid beta 1-42
-
(a) C.S. Atwood, R.S. Scarpa, X. Huang, R.D. Moir, W.D. Jones, D.P. Fairlie, R.E. Tanzi and A.I. Bush, Characterization of Copper Interactions with Alzheimer Amyloid Beta Peptides: Identification of an Attomoler-Affinity Copper Binding Site on Amyloid Beta 1-42, J. Neurochem. 75 (2000), 1219-1233.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1219-1233
-
-
Atwood, C.S.1
Scarpa, R.S.2
Huang, X.3
Moir, R.D.4
Jones, W.D.5
Fairlie, D.P.6
Tanzi, R.E.7
Bush, A.I.8
-
10
-
-
0032557425
-
Dramatic aggregation of Alzheimer's AΒ by Cu(II) is induced by conditions representing physiological acidosis
-
(b) C.S. Atwood, R.D. Moir, X. Huang, R.S. Scarpa, N.M.E. Bacarra, D.M. Romano, M.A. Hartshorn, R.E. Tanzi and A.I. Bush, Dramatic Aggregation of Alzheimer's AΒ by Cu(II) is induced by conditions representing physiological acidosis, J. Biol. Chem. 273 (1998), 12817-12826.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12817-12826
-
-
Atwood, C.S.1
Moir, R.D.2
Huang, X.3
Scarpa, R.S.4
Bacarra, N.M.E.5
Romano, D.M.6
Hartshorn, M.A.7
Tanzi, R.E.8
Bush, A.I.9
-
11
-
-
0034643831
-
Metal binding modes of Alzheimer's amyloid β-peptide in insoluble aggregates and soluble complexes
-
(c) T. Miura, K. Suzuki, N. Kohata and H. Takeuchi, Metal binding modes of Alzheimer's amyloid β-peptide in insoluble aggregates and soluble complexes, Biochemistry 39 (2000), 7024-7031.
-
(2000)
Biochemistry
, vol.39
, pp. 7024-7031
-
-
Miura, T.1
Suzuki, K.2
Kohata, N.3
Takeuchi, H.4
-
12
-
-
18344414746
-
The Ab Peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
X. Huang, C.S. Atwood, M.A. Hartshorn, G. Multhaup, L.E. Goldstein, R.S. Scarpa, M.P. Cuajungco, D.N. Gray, J. Lim, R.D. Moir, R.E. Tanzi and A.I. Bush, The Ab peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction, Biochemistry 38 (1999), 7609-7616.
-
(1999)
Biochemistry
, vol.38
, pp. 7609-7616
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
Multhaup, G.4
Goldstein, L.E.5
Scarpa, R.S.6
Cuajungco, M.P.7
Gray, D.N.8
Lim, J.9
Moir, R.D.10
Tanzi, R.E.11
Bush, A.I.12
-
14
-
-
0028178837
-
β-amyloid free radical fragments initiate synaptosomal lipid peroxidation in a sequence-specific fashion: Implications to Alzheimer's disease
-
D.A. Butterfield, K. Hensley, M. Harris, M.P. Mattson and J.M. Camey, Β-Amyloid Free Radical Fragments Initiate Synaptosomal Lipid Peroxidation in a Sequence-specific Fashion: Implications to Alzheimer's Disease, Biochem. Biophys. Res. Comm. 200 (1994), 710-715.
-
(1994)
Biochem. Biophys. Res. Comm.
, vol.200
, pp. 710-715
-
-
Butterfield, D.A.1
Hensley, K.2
Harris, M.3
Mattson, M.P.4
Camey, J.M.5
-
15
-
-
0028180518
-
A model for β-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer's disease
-
K. Hensley, J.M. Camey, M.P. Mattson, M. Aksenova, M. Harris, J.F. Wu, R.A. Floyd and D.A. Butterfield, A Model for Β-Amyloid Aggregation and Neurotoxicity Based on Free Radical Generation by the Peptide: Relevance to Alzheimer's Disease, Proc. Natl. Acad. Sci. 91 (1994), 3270-3274.
-
(1994)
Proc. Natl. Acad. Sci.
, vol.91
, pp. 3270-3274
-
-
Hensley, K.1
Camey, J.M.2
Mattson, M.P.3
Aksenova, M.4
Harris, M.5
Wu, J.F.6
Floyd, R.A.7
Butterfield, D.A.8
-
16
-
-
0000587221
-
Alzheimer's β-amyloid peptide and free radical oxidative stress
-
D.A. Gilbert and C.A. Colton, eds, Kluwer Academic/Plenum Press, New York
-
D.A. Butterfield, Alzheimer's β-amyloid peptide and free radical oxidative stress, in: Reactive Oxygen Species in Biological Systems, D.A. Gilbert and C.A. Colton, eds, Kluwer Academic/Plenum Press, New York, 1999, pp. 609-638.
-
(1999)
Reactive Oxygen Species in Biological Systems
, pp. 609-638
-
-
Butterfield, D.A.1
-
17
-
-
0005130098
-
Radical theory for Alzheimer's
-
C. Bostock-Smith, Radical theory for Alzheimer's, Chem. In Britain 36 (2000), 20.
-
(2000)
Chem. In Britain
, vol.36
, pp. 20
-
-
Bostock-Smith, C.1
-
18
-
-
0033621165
-
Amyloid diseases: Abnormal protein aggregation in neurodegeneration
-
E.H. Koo, P.T. Jr., Lansbury and J.W. Kelly, Amyloid Diseases: Abnormal protein aggregation in neurodegeneration, Proc. Natl. Acad. Sci. USA 96 (1999), 9989-9990.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9989-9990
-
-
Koo, E.H.1
Lansbury P.T., Jr.2
Kelly, J.W.3
-
19
-
-
0005181625
-
-
private Communication
-
D.A. Butterfield, private Communication.
-
-
-
Butterfield, D.A.1
-
20
-
-
0037082115
-
Redox processes of methionine relevant to β-amyloid oxidation and Alzheimer's disease
-
C. Schoneich, Redox processes of methionine relevant to β-amyloid oxidation and Alzheimer's disease, Arch. Biochem. Biophys. 397 (2002), 370-376.
-
(2002)
Arch. Biochem. Biophys.
, vol.397
, pp. 370-376
-
-
Schoneich, C.1
-
21
-
-
0034600281
-
Influence of β-sheet structure on the susceptibility of proteins to backbone oxidative damage: Preference for C-Centered radical formation at glycine residues of antiparallel β-sheets
-
A. Rauk and D.A. Armstrong, Influence of β-sheet structure on the susceptibility of proteins to backbone oxidative damage: Preference for C-Centered radical formation at glycine residues of antiparallel β-sheets, J. Am. Chem. Soc. 122 (2000), 4185-4192.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 4185-4192
-
-
Rauk, A.1
Armstrong, D.A.2
-
22
-
-
0034638379
-
Is oxidative damage by β-amyloid and prion peptides mediated by hydrogen atom transfer from glycine α-carbon to methionine sulfur within β-sheets?
-
A. Rauk, D.A. Armstrong and D.P. Fairlie, Is oxidative damage by β-amyloid and prion peptides mediated by hydrogen atom transfer from glycine α-carbon to methionine sulfur within β-sheets? J Am. Chem. Soc. 122 (2000), 9761-9767.
-
(2000)
J Am. Chem. Soc.
, vol.122
, pp. 9761-9767
-
-
Rauk, A.1
Armstrong, D.A.2
Fairlie, D.P.3
-
23
-
-
24544453084
-
Role of glycine-33 and methionine-35 in Alzheimer's amyloid β-peptide 1-42-associated oxidative stress and neurotoxicity
-
in press
-
J. Kanski, S. Varadarajan, M. Aksenova and D.A. Butterfield, Role of glycine-33 and methionine-35 in Alzheimer's amyloid β-peptide 1-42-associated oxidative stress and neurotoxicity, Biochim. Biophys. Acta (in press).
-
Biochim. Biophys. Acta
-
-
Kanski, J.1
Varadarajan, S.2
Aksenova, M.3
Butterfield, D.A.4
-
24
-
-
0034700129
-
Multiple quantum solid-state nmr indicates parallel, not antiparallel, organization of β-sheets in Alzheimer's β-amyloid fibrils
-
O.N. Antzutkin, J.J. Balbach, R.D. Leapman, N.W. Rizzo, J. Reed and R. Tycko, Multiple quantum solid-state nmr indicates parallel, not antiparallel, organization of β-sheets in Alzheimer's β-amyloid fibrils, Proc. Nat. Acad, Sci. 97 (2000), 13045-13050.
-
(2000)
Proc. Nat. Acad. Sci.
, vol.97
, pp. 13045-13050
-
-
Antzutkin, O.N.1
Balbach, J.J.2
Leapman, R.D.3
Rizzo, N.W.4
Reed, J.5
Tycko, R.6
-
25
-
-
0032796425
-
Amyloid β-sheet formation at the air-water interface
-
C. Schladitz, E.P. Vieira, H. Hermel and H. Mohwald, Amyloid β-sheet formation at the air-water interface, Biophys. J. 77 (1999), 3305-3310.
-
(1999)
Biophys. J.
, vol.77
, pp. 3305-3310
-
-
Schladitz, C.1
Vieira, E.P.2
Hermel, H.3
Mohwald, H.4
-
26
-
-
0026101636
-
Aggregation and secondary structure of synthetic amyloid bA4 peptides of Alzheimer's disease
-
C. Hilbich, B. Kisters-Woike, J. Reed, C.J. Masters and K. Beyreuther, Aggregation and secondary structure of synthetic amyloid bA4 peptides of Alzheimer's disease, J. Mol. Biol. 218 (1991), 149-163.
-
(1991)
J. Mol. Biol.
, vol.218
, pp. 149-163
-
-
Hilbich, C.1
Kisters-Woike, B.2
Reed, J.3
Masters, C.J.4
Beyreuther, K.5
-
27
-
-
0034663858
-
Accelerated accummulation of amyloid b proteins on oxidatively damaged lipid membranes
-
V. Koppaka and P.H. Axelsen, Accelerated accummulation of amyloid b proteins on oxidatively damaged lipid membranes, Biochemistry 39 (2000), 10011-10016.
-
(2000)
Biochemistry
, vol.39
, pp. 10011-10016
-
-
Koppaka, V.1
Axelsen, P.H.2
-
28
-
-
0033515394
-
A new ONIOM implementation in Gaussian98. Part I. The calculation of energies, gradients, vibrational frequencies and electric field derivatives
-
S. Dapprich, I. Komaromi, K.S. Byun, K. Morokuma and M.J. Frisch, A New ONIOM implementation in Gaussian98. Part I. The calculation of energies, gradients, vibrational frequencies and electric field derivatives, Mol. Struct. (THEO CHEM) 461-462 (1999), 1-21.
-
(1999)
Mol. Struct. (THEO CHEM)
, vol.461-462
, pp. 1-21
-
-
Dapprich, S.1
Komaromi, I.2
Byun, K.S.3
Morokuma, K.4
Frisch, M.J.5
-
29
-
-
0004133516
-
-
Gaussian, Inc., Pittsburgh PA
-
M.J. Frisch, G.W. Trucks, H.B. Schlegel, G.E. Scuseria, M.A. Robb, J.R. Cheeseman, V.G. Zakrzewski, J.A. Jr. Montgomery, R.E. Stratmann, J.C. Burant, S. Dapprich, J.M. Millam, A.D. Daniels, K.N. Kudin, M.C. Strain, O. Farkas, J. Tomasi, V. Barone, M. Cossi, R. Cammi, B. Mennucci, C. Pomelli, C. Adamo, S. Clifford, J. Ochterski, J.A. Petersson, P.Y. Ayala, Q. Cui, K. Morokuma, D.K. Malick, A.D. Rabuck, K. Raghavachari, J.B. Foresman, J. Cioslowski, J.V. Ortiz, A.G. Baboul, B.B. Stefanov, A. Liashenko, P. Piskorz, I. Komaromi, R. Gomperts, L.R. Martin, D.J. Fox, T. Keith, M.A. Al-Laham, C.Y. Peng, A. Nanayakkara, C. Gonzalez, M. Challacombe, P.M.W. Gill, B. Johnson, W. Chen, M.W. Wong, J.L. Andres, C. Gonzalez, M. Head-Gordon, E.S. Replogle and J.A. Pople, Gaussian 98, Revision A.7 1998, Gaussian, Inc., Pittsburgh PA.
-
(1998)
Gaussian 98, Revision A.7
-
-
Frisch, M.J.1
Trucks, G.W.2
Schlegel, H.B.3
Scuseria, G.E.4
Robb, M.A.5
Cheeseman, J.R.6
Zakrzewski, V.G.7
Montgomery J.A., Jr.8
Stratmann, R.E.9
Burant, J.C.10
Dapprich, S.11
Millam, J.M.12
Daniels, A.D.13
Kudin, K.N.14
Strain, M.C.15
Farkas, O.16
Tomasi, J.17
Barone, V.18
Cossi, M.19
Cammi, R.20
Mennucci, B.21
Pomelli, C.22
Adamo, C.23
Clifford, S.24
Ochterski, J.25
Petersson, J.A.26
Ayala, P.Y.27
Cui, Q.28
Morokuma, K.29
Malick, D.K.30
Rabuck, A.D.31
Raghavachari, K.32
Foresman, J.B.33
Cioslowski, J.34
Ortiz, J.V.35
Baboul, A.G.36
Stefanov, B.B.37
Liashenko, A.38
Piskorz, P.39
Komaromi, I.40
Gomperts, R.41
Martin, L.R.42
Fox, D.J.43
Keith, T.44
Al-Laham, M.A.45
Peng, C.Y.46
Nanayakkara, A.47
Gonzalez, C.48
Challacombe, M.49
Gill, P.M.W.50
Johnson, B.51
Chen, W.52
Wong, M.W.53
Andres, J.L.54
Gonzalez, C.55
Head-Gordon, M.56
Replogle, E.S.57
Pople, J.A.58
more..
-
30
-
-
0029011701
-
Generation force field for the simulation of proteins, nucleic acids, and organic molecules
-
W.D. Cornell, P. Cieplak, C.I. Bayly, I.R. Gould, K.M Merz, D.M. Ferguson, D.C. Spellmeyer, T. Fox, J.W. Caldwell and P.A. Kollman, A second generation force field for the simulation of proteins, nucleic acids, and organic molecules, J. Am. Chem. Soc. 117 (1995), 5179-5197.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 5179-5197
-
-
Cornell, W.D.1
Cieplak, P.2
Bayly, C.I.3
Gould, I.R.4
Merz, K.M.5
Ferguson, D.M.6
Spellmeyer, D.C.7
Fox, T.8
Caldwell, J.W.9
Kollman, P.A.10
Second, A.11
-
31
-
-
0030593395
-
Ability of emperical potential (AMBER, CHARMM, CVFF, OPLS, Poltev) and semi-empirical quantum chemical methods (AM1, MNDO/M, PM3) to describe H-bonding in DNA base pairs; comparaison with Ab initio results
-
P. Hobza, F. Hubálek, M. Kabelá, P. Mejzlík, J. Šponer and J. Vondrášek, Ability of emperical potential (AMBER, CHARMM, CVFF, OPLS, Poltev) and semi-empirical quantum chemical methods (AM1, MNDO/M, PM3) to describe H-bonding in DNA base pairs; comparaison with Ab initio results, Chem. Phys. Lett. 257 (1996), 31-35.
-
(1996)
Chem. Phys. Lett.
, vol.257
, pp. 31-35
-
-
Hobza, P.1
Hubálek, F.2
Kabelá, M.3
Mejzlík, P.4
Šponer, J.5
Vondrášek, J.6
-
32
-
-
0030175259
-
Oxidative damage to the glycyl α-carbon in proteins: An AΒ initio study of the C-H bond dissociation energy and the reduction potential of the C-Centered radical
-
D.A. Armstrong, D. Yu and A. Rauk, Oxidative damage to the glycyl α-carbon in proteins: An AΒ initio study of the C-H bond dissociation energy and the reduction potential of the C-Centered radical, Can. J. Chem. 74 (1996), 1192-1199.
-
(1996)
Can. J. Chem.
, vol.74
, pp. 1192-1199
-
-
Armstrong, D.A.1
Yu, D.2
Rauk, A.3
-
34
-
-
0029150955
-
Free energy determinants of secondary structure formation: II. Antiparallel β-sheets
-
A.S. Yang and B. Honig, Free energy determinants of secondary structure formation: II. Antiparallel β-sheets, J. Mol. Biol. 252 (1995), 366-376.
-
(1995)
J. Mol. Biol.
, vol.252
, pp. 366-376
-
-
Yang, A.S.1
Honig, B.2
|