-
2
-
-
0031668845
-
The assembly of triacylglycerol-rich lipoproteins: An essential role for the microsomal triacylglycerol transfer protein
-
D.A. White, A.J. Bennett, M.A. Billett, and A.M. Salter The assembly of triacylglycerol-rich lipoproteins: an essential role for the microsomal triacylglycerol transfer protein Br J Nutr 80 1998 219 229
-
(1998)
Br J Nutr
, vol.80
, pp. 219-229
-
-
White, D.A.1
Bennett, A.J.2
Billett, M.A.3
Salter, A.M.4
-
3
-
-
0026470990
-
Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia
-
J.R. Wetterau, L.P. Aggerbeck, M.E. Bouma, C. Eisenberg, A. Munck, and M. Hermeir Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia Science 258 1992 999 1001
-
(1992)
Science
, vol.258
, pp. 999-1001
-
-
Wetterau, J.R.1
Aggerbeck, L.P.2
Bouma, M.E.3
Eisenberg, C.4
Munck, A.5
Hermeir, M.6
-
4
-
-
0027428820
-
Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia
-
D. Sharp, L. Blinderman, K.A. Combs, B. Kienzle, B. Ricci, and K. Wager-Smith Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia Nature 365 1993 65 69
-
(1993)
Nature
, vol.365
, pp. 65-69
-
-
Sharp, D.1
Blinderman, L.2
Combs, K.A.3
Kienzle, B.4
Ricci, B.5
Wager-Smith, K.6
-
5
-
-
0033525712
-
Liver-specific inactivation of the abetalipoproteinemia gene completely abrogates very low density lipoprotein/low density lipoprotein production in a viable conditional knockout mouse
-
B.H. Chang, W. Liao, L. Li, M. Nakamuta, D. Mack, and L. Chan Liver-specific inactivation of the abetalipoproteinemia gene completely abrogates very low density lipoprotein/low density lipoprotein production in a viable conditional knockout mouse J Biol Chem 274 1999 6051 6055
-
(1999)
J Biol Chem
, vol.274
, pp. 6051-6055
-
-
Chang, B.H.1
Liao, W.2
Li, L.3
Nakamuta, M.4
MacK, D.5
Chan, L.6
-
6
-
-
0344349000
-
Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice
-
M. Raabe, M.M. Veniant, M.A. Sullivan, C.H. Zlot, J. Bjorkegren, and L.B. Nielsen Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice J Clin Invest 103 1999 1287 1298
-
(1999)
J Clin Invest
, vol.103
, pp. 1287-1298
-
-
Raabe, M.1
Veniant, M.M.2
Sullivan, M.A.3
Zlot, C.H.4
Bjorkegren, J.5
Nielsen, L.B.6
-
7
-
-
0032717454
-
Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B
-
U.J. Tietge, A. Bakillah, C. Maugeais, K. Tsukamoto, M. Hussain, and D.J. Rader Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B J Lipid Res 40 1999 2134 2139
-
(1999)
J Lipid Res
, vol.40
, pp. 2134-2139
-
-
Tietge, U.J.1
Bakillah, A.2
Maugeais, C.3
Tsukamoto, K.4
Hussain, M.5
Rader, D.J.6
-
8
-
-
0027945062
-
Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specific expression and response to metabolic regulators
-
D.L. Hagan, B. Kienzle, H. Jamil, and N. Hariharan Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specific expression and response to metabolic regulators J Biol Chem 269 1994 28737 28744
-
(1994)
J Biol Chem
, vol.269
, pp. 28737-28744
-
-
Hagan, D.L.1
Kienzle, B.2
Jamil, H.3
Hariharan, N.4
-
9
-
-
13944249827
-
Transcriptional regulation of human microsomal triglyceride transfer protein by hepatocyte nuclear factor-4α
-
V. Sheena, R. Hertz, J. Nousbeck, I. Berman, J. Magenheim, and J. Bar-Tana Transcriptional regulation of human microsomal triglyceride transfer protein by hepatocyte nuclear factor-4α J Lipid Res 46 2005 328 341
-
(2005)
J Lipid Res
, vol.46
, pp. 328-341
-
-
Sheena, V.1
Hertz, R.2
Nousbeck, J.3
Berman, I.4
Magenheim, J.5
Bar-Tana, J.6
-
10
-
-
0032561425
-
An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits
-
J.R. Wetterau, R.E. Gregg, T.W. Harrity, C. Arbeeny, M. Cap, and F. Connolly An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits Science 82 1998 751 754
-
(1998)
Science
, vol.82
, pp. 751-754
-
-
Wetterau, J.R.1
Gregg, R.E.2
Harrity, T.W.3
Arbeeny, C.4
Cap, M.5
Connolly, F.6
-
11
-
-
0242290829
-
CP-346086: An MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans
-
C.E. Chandler, D.E. Wilder, J.L. Pettini, Y.E. Savoy, S.F. Petras, and G. Chang CP-346086: an MTP inhibitor that lowers plasma cholesterol and triglycerides in experimental animals and in humans J Lipid Res 4 2003 1887 1901
-
(2003)
J Lipid Res
, vol.4
, pp. 1887-1901
-
-
Chandler, C.E.1
Wilder, D.E.2
Pettini, J.L.3
Savoy, Y.E.4
Petras, S.F.5
Chang, G.6
-
12
-
-
0035924183
-
Diaminoindanes as microsomal triglyceride transfer protein inhibitors
-
G.M. Ksander, R. deJesus, A. Yuan, C. Fink, M. Moskal, and E. Carlson Diaminoindanes as microsomal triglyceride transfer protein inhibitors J Med Chem 44 2001 4677 4687
-
(2001)
J Med Chem
, vol.44
, pp. 4677-4687
-
-
Ksander, G.M.1
Dejesus, R.2
Yuan, A.3
Fink, C.4
Moskal, M.5
Carlson, E.6
-
13
-
-
0032473950
-
Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4alpha
-
R. Hertz, J. Magenheim, I. Berman, and J. Bar-Tana Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4alpha Nature 392 1998 512 516
-
(1998)
Nature
, vol.392
, pp. 512-516
-
-
Hertz, R.1
Magenheim, J.2
Berman, I.3
Bar-Tana, J.4
-
14
-
-
0035342271
-
Suppression of hepatocyte nuclear factor-4alpha by acyl-CoA thioesters of hypolipidemic peroxisome proliferators
-
R. Hertz, V. Sheena, B. Kalderon, I. Berman, and J. Bar-Tana Suppression of hepatocyte nuclear factor-4alpha by acyl-CoA thioesters of hypolipidemic peroxisome proliferators Biochem Pharmacol 61 2001 1057 1062
-
(2001)
Biochem Pharmacol
, vol.61
, pp. 1057-1062
-
-
Hertz, R.1
Sheena, V.2
Kalderon, B.3
Berman, I.4
Bar-Tana, J.5
-
15
-
-
0037376373
-
Adipose tissue sensitization to insulin induced by troglitazone and MEDICA 16 in obese Zucker rats in vivo
-
B. Kalderon, N. Mayorek, L. Ben-Yaacov, and J. Bar-Tana Adipose tissue sensitization to insulin induced by troglitazone and MEDICA 16 in obese Zucker rats in vivo Am J Physiol Endocrinol Metab 284 2003 E795 E803
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
-
-
Kalderon, B.1
Mayorek, N.2
Ben-Yaacov, L.3
Bar-Tana, J.4
-
16
-
-
0025150912
-
Effects of fish oil on VLDL triglyceride kinetics in humans
-
W.S. Harris, W.E. Connor, D.R. Illingworth, D.W. Rothrock, and D.M. Foster Effects of fish oil on VLDL triglyceride kinetics in humans J Lipid Res 31 1990 1549 1558
-
(1990)
J Lipid Res
, vol.31
, pp. 1549-1558
-
-
Harris, W.S.1
Connor, W.E.2
Illingworth, D.R.3
Rothrock, D.W.4
Foster, D.M.5
-
17
-
-
0032506273
-
Mechanism of action of fibrates on lipid and lipoprotein metabolism
-
B. Staels, J. Dallongeville, J. Auwerz, K. Schoonjans, E. Leitersdorf, and J.C. Fruchart Mechanism of action of fibrates on lipid and lipoprotein metabolism Circulation 98 1998 2088 2093
-
(1998)
Circulation
, vol.98
, pp. 2088-2093
-
-
Staels, B.1
Dallongeville, J.2
Auwerz, J.3
Schoonjans, K.4
Leitersdorf, E.5
Fruchart, J.C.6
-
18
-
-
0035993444
-
Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis
-
H. Vosper, G.A. Khoudoli, T.L. Graham, and C.N. Palmer Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis Pharmacol Ther 95 2002 47 62
-
(2002)
Pharmacol Ther
, vol.95
, pp. 47-62
-
-
Vosper, H.1
Khoudoli, G.A.2
Graham, T.L.3
Palmer, C.N.4
-
19
-
-
1042268097
-
Impact of adjunctive thiazolidinedione therapy on blood lipid levels and glycemic control in patients with type 2 diabetes
-
A.L. Peters Harmel, D.M. Kendall, J.B. Buse, P.J. Boyle, A. Marchetti, and H. Lau Impact of adjunctive thiazolidinedione therapy on blood lipid levels and glycemic control in patients with type 2 diabetes Curr Med Res Opin 20 2004 215 223
-
(2004)
Curr Med Res Opin
, vol.20
, pp. 215-223
-
-
Peters Harmel, A.L.1
Kendall, D.M.2
Buse, J.B.3
Boyle, P.J.4
Marchetti, A.5
Lau, H.6
-
20
-
-
0034919411
-
The impact of pioglitazone on glycemic control and atherogenic dyslipidemia in patients with type 2 diabetes mellitus
-
Pioglitazone 026 Study Group K.E.
-
S. Rosenblatt, B. Miskin, N.B. Glazer, M.J. Prince, K.E. Robertson Pioglitazone 026 Study Group The impact of pioglitazone on glycemic control and atherogenic dyslipidemia in patients with type 2 diabetes mellitus Coron Artery Dis 12 2001 413 423
-
(2001)
Coron Artery Dis
, vol.12
, pp. 413-423
-
-
Rosenblatt, S.1
Miskin, B.2
Glazer, N.B.3
Prince, M.J.4
Robertson5
-
21
-
-
0032727659
-
Thiazolidinediones: A new class of antidiabetic drugs
-
C. Day Thiazolidinediones: a new class of antidiabetic drugs Diabet Med 16 1999 179 192
-
(1999)
Diabet Med
, vol.16
, pp. 179-192
-
-
Day, C.1
-
22
-
-
0033821707
-
Troglitazone prevents and reverses dyslipidemia, insulin secretory defects, and histologic abnormalities in a rat model of naturally occurring obese diabetes
-
D.M. Jia, A. Tabaru, H. Nakamura, K.I. Fukumitsu, T. Akiyama, and M. Otsuki Troglitazone prevents and reverses dyslipidemia, insulin secretory defects, and histologic abnormalities in a rat model of naturally occurring obese diabetes Metabolism 49 2000 1167 1175
-
(2000)
Metabolism
, vol.49
, pp. 1167-1175
-
-
Jia, D.M.1
Tabaru, A.2
Nakamura, H.3
Fukumitsu, K.I.4
Akiyama, T.5
Otsuki, M.6
-
23
-
-
0034708682
-
Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model
-
A. Carpentier, C. Taghibiglou, S.C. Van Iderstine, B. Chen, D. Rudy, and A. Aiton Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model J Biol Chem 275 2000 8416 8425
-
(2000)
J Biol Chem
, vol.275
, pp. 8416-8425
-
-
Carpentier, A.1
Taghibiglou, C.2
Van Iderstine, S.C.3
Chen, B.4
Rudy, D.5
Aiton, A.6
-
24
-
-
12544259675
-
Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver
-
C. Ameen, U. Edvardsson, A. Ljungberg, L. Asp, P. Akerblad, and A. Tuneld Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver J Biol Chem 280 2005 1224 1229
-
(2005)
J Biol Chem
, vol.280
, pp. 1224-1229
-
-
Ameen, C.1
Edvardsson, U.2
Ljungberg, A.3
Asp, L.4
Akerblad, P.5
Tuneld, A.6
-
25
-
-
0043234719
-
ARP-1/COUP-TF II determines hepatoma phenotype by acting as both a transcriptional repressor of microsomal triglyceride transfer protein and an inducer of CYP7A1
-
S. Kang, N.J. Spann, T.Y. Hui, and R.A. Davis ARP-1/COUP-TF II determines hepatoma phenotype by acting as both a transcriptional repressor of microsomal triglyceride transfer protein and an inducer of CYP7A1 J Biol Chem 278 2003 30478 30486
-
(2003)
J Biol Chem
, vol.278
, pp. 30478-30486
-
-
Kang, S.1
Spann, N.J.2
Hui, T.Y.3
Davis, R.A.4
-
26
-
-
0028998129
-
Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression of apolipoprotein C-III
-
R. Hertz, J. Bishara-Shieban, and J. Bar-Tana Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression of apolipoprotein C-III J Biol Chem 270 1995 13470 13475
-
(1995)
J Biol Chem
, vol.270
, pp. 13470-13475
-
-
Hertz, R.1
Bishara-Shieban, J.2
Bar-Tana, J.3
-
27
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
I. Issemann, and S. Green Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators Nature 347 1990 645 650
-
(1990)
Nature
, vol.347
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
28
-
-
0028988487
-
PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
-
P. Tontonoz, E. Hu, J. Devine, E.G. Beale, and B.M. Spiegelman PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene Mol Cell Biol 15 1995 351 357
-
(1995)
Mol Cell Biol
, vol.15
, pp. 351-357
-
-
Tontonoz, P.1
Hu, E.2
Devine, J.3
Beale, E.G.4
Spiegelman, B.M.5
-
29
-
-
0024433742
-
Synthesis and hypolipidemic and antidiabetogenic activities of beta,beta,beta′,beta′-tetrasubstituted, long-chain dioic acids
-
J. Bar-Tana, S. Ben-Shoshan, J. Blum, Y. Migron, R. Hertz, and J. Pill Synthesis and hypolipidemic and antidiabetogenic activities of beta,beta,beta′,beta′-tetrasubstituted, long-chain dioic acids J Med Chem 9 1989 2072 2084
-
(1989)
J Med Chem
, vol.9
, pp. 2072-2084
-
-
Bar-Tana, J.1
Ben-Shoshan, S.2
Blum, J.3
Migron, Y.4
Hertz, R.5
Pill, J.6
-
30
-
-
8544256355
-
Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4
-
H. Hirokane, M. Nakahara, S. Tachibana, M. Shimizu, and R. Sato Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4 Biol Chem 279 2004 45685 45692
-
(2004)
Biol Chem
, vol.279
, pp. 45685-45692
-
-
Hirokane, H.1
Nakahara, M.2
Tachibana, S.3
Shimizu, M.4
Sato, R.5
-
31
-
-
0028218398
-
The effect of beta,beta′-tetramethylhexadecanedioic acid (MEDICA 16) on plasma very-low-density lipoprotein metabolism in rats: Role of apolipoprotein C-III
-
B. Frenkel, J. Bishara-Shieban, and J. Bar-Tana The effect of beta,beta′-tetramethylhexadecanedioic acid (MEDICA 16) on plasma very-low-density lipoprotein metabolism in rats: role of apolipoprotein C-III Biochem J 298 1994 409 414
-
(1994)
Biochem J
, vol.298
, pp. 409-414
-
-
Frenkel, B.1
Bishara-Shieban, J.2
Bar-Tana, J.3
-
32
-
-
0036319163
-
Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro
-
P.G. McTernan, A.L. Harte, L.A. Anderson, A. Green, S.A. Smith, and J.C. Holder Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro Diabetes 51 2002 1493 1498
-
(2002)
Diabetes
, vol.51
, pp. 1493-1498
-
-
McTernan, P.G.1
Harte, A.L.2
Anderson, L.A.3
Green, A.4
Smith, S.A.5
Holder, J.C.6
-
33
-
-
3042760032
-
The effect of pioglitazone on peroxisome proliferators-activated receptor-gamma target genes related to lipid storage in vivo
-
I. Bogacka, H. Xie, G.A. Bray, and S.R. Smith The effect of pioglitazone on peroxisome proliferators-activated receptor-gamma target genes related to lipid storage in vivo Diabetes Care 27 2004 1660 1667
-
(2004)
Diabetes Care
, vol.27
, pp. 1660-1667
-
-
Bogacka, I.1
Xie, H.2
Bray, G.A.3
Smith, S.R.4
-
34
-
-
0032439396
-
Peroxisome proliferator-activated receptor (PPAR) alpha activation and its consequences in humans
-
R. Hertz, and J. Bar-Tana Peroxisome proliferator-activated receptor (PPAR) alpha activation and its consequences in humans Toxicol Lett 102-103 1998 85 90
-
(1998)
Toxicol Lett
, vol.102-103
, pp. 85-90
-
-
Hertz, R.1
Bar-Tana, J.2
-
35
-
-
0031838516
-
Do peroxisome proliferating compounds pose a hepatocarcinogenic hazard to humans?
-
R.C. Cattley, J. DeLuca, C. Elcombe, P. Fenner-Crisp, B.G. Lake, and D.S. Marsman Do peroxisome proliferating compounds pose a hepatocarcinogenic hazard to humans? Regul Toxicol Pharmacol 27 1998 47 60
-
(1998)
Regul Toxicol Pharmacol
, vol.27
, pp. 47-60
-
-
Cattley, R.C.1
Deluca, J.2
Elcombe, C.3
Fenner-Crisp, P.4
Lake, B.G.5
Marsman, D.S.6
-
36
-
-
16644363226
-
Hypolipidemia induced by PPARalpha agonists: HNF-4alpha as an alternative to PPARalpha
-
J. Bar-Tana Hypolipidemia induced by PPARalpha agonists: HNF-4alpha as an alternative to PPARalpha Curr Opin Investig Drugs 5 2004 941 946
-
(2004)
Curr Opin Investig Drugs
, vol.5
, pp. 941-946
-
-
Bar-Tana, J.1
-
37
-
-
0032995560
-
The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: Significance for species differences in response to PPs
-
N.J. Woodyatt, K.G. Lambe, K.A. Myers, J.D. Tugwood, and R.A. Roberts The peroxisome proliferator (PP) response element upstream of the human acyl CoA oxidase gene is inactive among a sample human population: significance for species differences in response to PPs Carcinogenesis 20 1999 369 372
-
(1999)
Carcinogenesis
, vol.20
, pp. 369-372
-
-
Woodyatt, N.J.1
Lambe, K.G.2
Myers, K.A.3
Tugwood, J.D.4
Roberts, R.A.5
-
38
-
-
0034065023
-
Species differences in response to diethylhexylphthalate: Suppression of apoptosis, induction of DNA synthesis and peroxisome proliferator activated receptor alpha-mediated gene expression
-
S.C. Hasmall, N.H. James, N. Macdonald, A.R. Soames, and R.A. Roberts Species differences in response to diethylhexylphthalate: suppression of apoptosis, induction of DNA synthesis and peroxisome proliferator activated receptor alpha-mediated gene expression Arch Toxicol 74 2000 85 91
-
(2000)
Arch Toxicol
, vol.74
, pp. 85-91
-
-
Hasmall, S.C.1
James, N.H.2
MacDonald, N.3
Soames, A.R.4
Roberts, R.A.5
-
39
-
-
2442693900
-
CD1d function is regulated by microsomal triglyceride transfer protein
-
S. Brozovic, T. Nagaishi, M. Yoshida, S. Betz, A. Salas, and D. Chen CD1d function is regulated by microsomal triglyceride transfer protein Nat Med 10 2004 535 539
-
(2004)
Nat Med
, vol.10
, pp. 535-539
-
-
Brozovic, S.1
Nagaishi, T.2
Yoshida, M.3
Betz, S.4
Salas, A.5
Chen, D.6
|