-
2
-
-
17144417748
-
Dendritic cells as therapeutic vaccines against cancer
-
Banchereau J, Palucka AK. Dendritic cells as therapeutic vaccines against cancer. Nature Rev. Immunol. 5(4), 296-306 (2005).
-
(2005)
Nature Rev. Immunol.
, vol.5
, Issue.4
, pp. 296-306
-
-
Banchereau, J.1
Palucka, A.K.2
-
3
-
-
10644262982
-
Plasmacytoid dendritic cells: Linking innate and adaptive immunity
-
McKenna K, Beignon AS, Bhardwaj N. Plasmacytoid dendritic cells: linking innate and adaptive immunity. J Virol. 79(1), 17-27 (2005).
-
(2005)
J. Virol.
, vol.79
, Issue.1
, pp. 17-27
-
-
McKenna, K.1
Beignon, A.S.2
Bhardwaj, N.3
-
4
-
-
0033993529
-
Dendritic cell-based vaccines: From mouse models to clinical cancer immunotherapy
-
Schreurs MW, Eggert AA, Punt CJ, Figdor CG, Adema GJ. Dendritic cell-based vaccines: from mouse models to clinical cancer immunotherapy. Crit. Rev. Oncog. 11(1), 1-17 (2000).
-
(2000)
Crit. Rev. Oncog.
, vol.11
, Issue.1
, pp. 1-17
-
-
Schreurs, M.W.1
Eggert, A.A.2
Punt, C.J.3
Figdor, C.G.4
Adema, G.J.5
-
5
-
-
0031978249
-
Immunotherapy of cancer with dendritic-cell-based vaccines
-
Gilboa E, Nair SK, Lyerly HK. Immunotherapy of cancer with dendritic-cell-based vaccines. Cancer Immunol. Immunother. 46(2), 82-87 (1998).
-
(1998)
Cancer Immunol. Immunother.
, vol.46
, Issue.2
, pp. 82-87
-
-
Gilboa, E.1
Nair, S.K.2
Lyerly, H.K.3
-
6
-
-
2442647551
-
Dendritic cell immunotherapy: Mapping the way
-
Figdor CG, de Vries IJ, Lesterhuis WJ, Melief CJ. Dendritic cell immunotherapy: mapping the way. Nature Med. 10(5), 475-480 (2004). Clear review detailing the latest clinical results in dendritic cell (DC) vaccination.
-
(2004)
Nature Med.
, vol.10
, Issue.5
, pp. 475-480
-
-
Figdor, C.G.1
De Vries, I.J.2
Lesterhuis, W.J.3
Melief, C.J.4
-
7
-
-
4644324025
-
Cancer immunotherapy: Moving beyond current vaccines
-
Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nature Med. 10(9), 909-915 (2004).
-
(2004)
Nature Med.
, vol.10
, Issue.9
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
8
-
-
10744224631
-
Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients
-
De Vries IJ, Lesterhuis WJ, Scharenborg NM et al. Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients. Clin. Cancer Res. 9(14), 5091-5100 (2003).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.14
, pp. 5091-5100
-
-
De Vries, I.J.1
Lesterhuis, W.J.2
Scharenborg, N.M.3
-
9
-
-
2942559009
-
Cancer immunotherapy with mRNA-transfected dendritic cells
-
Gilboa E, Vieweg J. Cancer immunotherapy with mRNA-transfected dendritic cells. Immunol. Rev. 199, 251-263 (2004).
-
(2004)
Immunol. Rev.
, vol.199
, pp. 251-263
-
-
Gilboa, E.1
Vieweg, J.2
-
10
-
-
0031941423
-
Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
-
Nestle FO, Alijagic S, Gilliet M et al. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nature Med. 4(3), 328-332 (1998).
-
(1998)
Nature Med.
, vol.4
, Issue.3
, pp. 328-332
-
-
Nestle, F.O.1
Alijagic, S.2
Gilliet, M.3
-
11
-
-
0030763047
-
Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: Pathway of presentation and regulation by cytokines
-
Brossart P, Bevan MJ. Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: pathway of presentation and regulation by cytokines. Blood 90(4), 1594-1599 (1997).
-
(1997)
Blood
, vol.90
, Issue.4
, pp. 1594-1599
-
-
Brossart, P.1
Bevan, M.J.2
-
12
-
-
3042523520
-
Targeting dendritic cells with antigen-containing liposomes: A highly effective procedure for induction of antitumor immunity and for tumor immunotherapy
-
van Broekhoven CL, Parish CR, Demangel C, Britton WJ, Altin JG. Targeting dendritic cells with antigen-containing liposomes: a highly effective procedure for induction of antitumor immunity and for tumor immunotherapy. Cancer Res. 64(12), 4357-4365 (2004).
-
(2004)
Cancer Res.
, vol.64
, Issue.12
, pp. 4357-4365
-
-
Van Broekhoven, C.L.1
Parish, C.R.2
Demangel, C.3
Britton, W.J.4
Altin, J.G.5
-
13
-
-
0031863853
-
Eradication of established murine tumors using a novel cell-free vaccine: Dendritic cell-derived exosomes
-
Zitvogel L, Regnault A, Lozier A et al. Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes. Nature Med. 4(5), 594-600 (1998).
-
(1998)
Nature Med.
, vol.4
, Issue.5
, pp. 594-600
-
-
Zitvogel, L.1
Regnault, A.2
Lozier, A.3
-
15
-
-
20044396550
-
Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas
-
Mazzolini G, Alfaro C, Sangro B et al. Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas. J. Clin. Oncol. 23(5), 999-1010 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.5
, pp. 999-1010
-
-
Mazzolini, G.1
Alfaro, C.2
Sangro, B.3
-
16
-
-
0017126775
-
Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay
-
Bevan MJ. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp. Med. 143(5), 1283-1288 (1976).
-
(1976)
J. Exp. Med.
, vol.143
, Issue.5
, pp. 1283-1288
-
-
Bevan, M.J.1
-
17
-
-
2542616960
-
Antigen bias in T cell cross-priming
-
Wolkers MC, Brouwenstijn N, Bakker AH, Toebes M, Schumacher TN. Antigen bias in T cell cross-priming. Science 304(5675), 1314-1317 (2004).
-
(2004)
Science
, vol.304
, Issue.5675
, pp. 1314-1317
-
-
Wolkers, M.C.1
Brouwenstijn, N.2
Bakker, A.H.3
Toebes, M.4
Schumacher, T.N.5
-
18
-
-
0038491296
-
Presentation of exogenous antigens on major histocompatibility complex (MHC) class I and MHC class II molecules is differentially regulated during dendritic cell maturation
-
Delamarre L, Holcombe H, Mellman I. Presentation of exogenous antigens on major histocompatibility complex (MHC) class I and MHC class II molecules is differentially regulated during dendritic cell maturation. J. Exp. Med. 198(1), 111-122 (2003).
-
(2003)
J. Exp. Med.
, vol.198
, Issue.1
, pp. 111-122
-
-
Delamarre, L.1
Holcombe, H.2
Mellman, I.3
-
19
-
-
0037446752
-
A subset of Toll-like receptor ligands induces cross-presentation by bone marrow-derived dendritic cells
-
Datta SK, Redecke V, Prilliman KR et al. A subset of Toll-like receptor ligands induces cross-presentation by bone marrow-derived dendritic cells. J. Immunol. 170(8), 4102-4110 (2003).
-
(2003)
J. Immunol.
, vol.170
, Issue.8
, pp. 4102-4110
-
-
Datta, S.K.1
Redecke, V.2
Prilliman, K.R.3
-
20
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nature Rev. Immunol. 3(2), 133-146 (2003).
-
(2003)
Nature Rev. Immunol.
, vol.3
, Issue.2
, pp. 133-146
-
-
Trinchieri, G.1
-
21
-
-
0037066427
-
The danger model: A renewed sense of self
-
Matzinger P. The danger model: a renewed sense of self. Science 296(5566), 301-305 (2002).
-
(2002)
Science
, vol.296
, Issue.5566
, pp. 301-305
-
-
Matzinger, P.1
-
23
-
-
5444262511
-
Toll-like receptor control of die adaptive immune responses
-
Iwasaki A, Medzhitov R. Toll-like receptor control of die adaptive immune responses. Nature Immunol. 5(10), 987-995 (2004).
-
(2004)
Nature Immunol.
, vol.5
, Issue.10
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
25
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S, Takeda K. Toll-like receptor signalling. Nature Rev. Immunol. 4(7), 499-511 (2004). Extensive review on Toll-like receptor (TLR) signaling.
-
(2004)
Nature Rev. Immunol.
, vol.4
, Issue.7
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
26
-
-
20644433342
-
TLR11 Activation of dendritic cells by a protozoan profilin-like protein
-
Yarovinsky F, Zhang D, Andersen JF et al. TLR11 Activation of dendritic cells by a protozoan profilin-like protein. Science 308(5728), 1626-1629 (2005).
-
(2005)
Science
, vol.308
, Issue.5728
, pp. 1626-1629
-
-
Yarovinsky, F.1
Zhang, D.2
Andersen, J.F.3
-
27
-
-
20044368019
-
Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88
-
Hasan U, Chaffois C, Gaillard C et al. Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88. J. Immunol. 174(5), 2942-2950 (2005).
-
(2005)
J. Immunol.
, vol.174
, Issue.5
, pp. 2942-2950
-
-
Hasan, U.1
Chaffois, C.2
Gaillard, C.3
-
28
-
-
0035903288
-
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
-
Kadowaki N, Ho S, Antonenko S et al. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J. Exp. Med. 194(6), 863-869 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, Issue.6
, pp. 863-869
-
-
Kadowaki, N.1
Ho, S.2
Antonenko, S.3
-
29
-
-
0035179882
-
Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
-
Jarrossay D, Napolitani G, Colonna M, Sallusto F, Lanzavecchia A. Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur. J. Immunol. 31(11), 3388-3393 (2001).
-
(2001)
Eur. J. Immunol.
, vol.31
, Issue.11
, pp. 3388-3393
-
-
Jarrossay, D.1
Napolitani, G.2
Colonna, M.3
Sallusto, F.4
Lanzavecchia, A.5
-
31
-
-
0035879893
-
A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection
-
Jonuleit H, Giesecke-Tuettenberg A, Tuting T et al. A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection. Int. J. Cancer 93(2), 243-251 (2001).
-
(2001)
Int. J. Cancer
, vol.93
, Issue.2
, pp. 243-251
-
-
Jonuleit, H.1
Giesecke-Tuettenberg, A.2
Tuting, T.3
-
32
-
-
4344596051
-
α-type-1 polarized dendritic cells: A novel immunization tool with optimized CTL-inducing activity
-
Mailliard RB, Wankowicz-Kalinska A, Cai Q et al. α-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity. Cancer Res. 64(17), 5934-5937 (2004).
-
(2004)
Cancer Res.
, vol.64
, Issue.17
, pp. 5934-5937
-
-
Mailliard, R.B.1
Wankowicz-Kalinska, A.2
Cai, Q.3
-
33
-
-
13944260898
-
+ T-cell populations lacking helper function
-
+ T-cell populations lacking helper function. Nature Immunol. 6(2), 163-170 (2005). Clearly demonstrates that pathogen components are essential to efficiently direct helper T-cell differentiation.
-
(2005)
Nature Immunol.
, vol.6
, Issue.2
, pp. 163-170
-
-
Sporri, R.1
Reis E Sousa, C.2
-
34
-
-
14044257261
-
Variegation of the immune response with dendritic cells and pathogen recognition receptors
-
Pulendran B. Variegation of the immune response with dendritic cells and pathogen recognition receptors. J. Immunol. 174(5), 2457-2465 (2005).
-
(2005)
J. Immunol.
, vol.174
, Issue.5
, pp. 2457-2465
-
-
Pulendran, B.1
-
35
-
-
0037226599
-
Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state
-
De Vries IJ, Krooshoop DJ, Scharenborg NM et al. Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res. 63(1), 12-17 (2003).
-
(2003)
Cancer Res.
, vol.63
, Issue.1
, pp. 12-17
-
-
De Vries, I.J.1
Krooshoop, D.J.2
Scharenborg, N.M.3
-
36
-
-
14844295742
-
Migration of dendritic cell based cancer vaccines: In vivo veritas?
-
Adema GJ, de Vries IJ, Punt CJ, Figdor CG. Migration of dendritic cell based cancer vaccines: in vivo veritas? Curr. Opin. Immunol. 17(2), 170-174 (2005).
-
(2005)
Curr. Opin. Immunol.
, vol.17
, Issue.2
, pp. 170-174
-
-
Adema, G.J.1
De Vries, I.J.2
Punt, C.J.3
Figdor, C.G.4
-
37
-
-
2142697904
-
In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity
-
discussion 254-269
-
Vicari AP, Vanbervliet B, Massacrier C et al. In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity. Novartis Found Symp. 256, 241-254; discussion 254-269 (2004).
-
(2004)
Novartis Found Symp.
, vol.256
, pp. 241-254
-
-
Vicari, A.P.1
Vanbervliet, B.2
Massacrier, C.3
-
38
-
-
0033214348
-
CCR7 co-ordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
-
Forster R, Schubel A, Breitfeld D et al. CCR7 co-ordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99(1), 23-33 (1999).
-
(1999)
Cell
, vol.99
, Issue.1
, pp. 23-33
-
-
Forster, R.1
Schubel, A.2
Breitfeld, D.3
-
39
-
-
4143096772
-
CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions
-
Ohl L, Mohaupt M, Czeloth N et al. CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity 21(2), 279-288 (2004).
-
(2004)
Immunity
, vol.21
, Issue.2
, pp. 279-288
-
-
Ohl, L.1
Mohaupt, M.2
Czeloth, N.3
-
40
-
-
5644273775
-
Dyslipidemia associated with atherosclerotic disease systemically alters dendritic cell mobilization
-
Angeli V, Llodra J, Rong JX et al. Dyslipidemia associated with atherosclerotic disease systemically alters dendritic cell mobilization. Immunity 21(4), 561-574 (2004).
-
(2004)
Immunity
, vol.21
, Issue.4
, pp. 561-574
-
-
Angeli, V.1
Llodra, J.2
Rong, J.X.3
-
41
-
-
5444267347
-
Crucial functions of the Rap 1 effector molecule RAPL in lymphocyte and dendritic cell trafficking
-
Katagiri K, Ohnishi N, Kabashima K et al. Crucial functions of the Rap 1 effector molecule RAPL in lymphocyte and dendritic cell trafficking. Nature Immunol. 5(10), 1045-1051 (2004).
-
(2004)
Nature Immunol.
, vol.5
, Issue.10
, pp. 1045-1051
-
-
Katagiri, K.1
Ohnishi, N.2
Kabashima, K.3
-
42
-
-
0033565923
-
Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration
-
Eggert AA, Schreurs MW, Boerman OC et al. Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration. Cancer Res. 59(14), 3340-3345 (1999).
-
(1999)
Cancer Res.
, vol.59
, Issue.14
, pp. 3340-3345
-
-
Eggert, A.A.1
Schreurs, M.W.2
Boerman, O.C.3
-
43
-
-
0034614892
-
TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo
-
Josien R, Li HL, Ingulli E et al. TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo. J. Exp. Med. 191(3), 495-502 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, Issue.3
, pp. 495-502
-
-
Josien, R.1
Li, H.L.2
Ingulli, E.3
-
44
-
-
0141993954
-
Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control
-
Mullins DW, Sheasley SL, Ream RM et al. Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control. J. Exp. Med. 198(7), 1023-1034 (2003). Demonstrates that the route of immunization of DCs affects the location of tumor immunity.
-
(2003)
J. Exp. Med.
, vol.198
, Issue.7
, pp. 1023-1034
-
-
Mullins, D.W.1
Sheasley, S.L.2
Ream, R.M.3
-
45
-
-
20544433550
-
Peptides chaperoned by heat-shock proteins are a necessary and sufficient source of antigen in the cross-priming of CD8(+) T cells
-
Binder RJ, Srivastava PK. Peptides chaperoned by heat-shock proteins are a necessary and sufficient source of antigen in the cross-priming of CD8(+) T cells. Nature Immunol. 6(6), 593-599 (2005).
-
(2005)
Nature Immunol.
, vol.6
, Issue.6
, pp. 593-599
-
-
Binder, R.J.1
Srivastava, P.K.2
-
46
-
-
2942752015
-
Coupling of antigen to cholera toxin for dendritic cell vaccination promotes the induction of MHC class I-restricted cytotoxic T cells and the rejection of a cognate antigen-expressing model tumor
-
Eriksson K, Sun JB, Nordstrom I et al. Coupling of antigen to cholera toxin for dendritic cell vaccination promotes the induction of MHC class I-restricted cytotoxic T cells and the rejection of a cognate antigen-expressing model tumor. Eur.J. Immunol. 34(5), 1272-1281 (2004).
-
(2004)
Eur.J. Immunol.
, vol.34
, Issue.5
, pp. 1272-1281
-
-
Eriksson, K.1
Sun, J.B.2
Nordstrom, I.3
-
47
-
-
0041428118
-
In vivo, dendritic cells can cross-present virus-like particles using an endosome-to-cytosol pathway
-
Moron VG, Rueda P, Sedlik C, Leclerc C. In vivo, dendritic cells can cross-present virus-like particles using an endosome-to-cytosol pathway. J. Immunol. 171(5), 2242-2250 (2003).
-
(2003)
J. Immunol.
, vol.171
, Issue.5
, pp. 2242-2250
-
-
Moron, V.G.1
Rueda, P.2
Sedlik, C.3
Leclerc, C.4
-
48
-
-
12144286596
-
In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination
-
Bonifaz LC, Bonnyay DP, Charalambous A et al. In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J. Exp. Med. 199(6), 815-824 (2004). Important paper showing for the first time that in vivo antibody targeting to DCs could induce cross presentation to T-cells.
-
(2004)
J. Exp. Med.
, vol.199
, Issue.6
, pp. 815-824
-
-
Bonifaz, L.C.1
Bonnyay, D.P.2
Charalambous, A.3
-
49
-
-
0035903326
-
Dendritic cells induce peripheral T cell unresponsiveness under steady-state conditions in vivo
-
Hawiger D, Inaba K, Dorsett Y et al. Dendritic cells induce peripheral T cell unresponsiveness under steady-state conditions in vivo. J. Exp. Med. 194(6), 769-779 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, Issue.6
, pp. 769-779
-
-
Hawiger, D.1
Inaba, K.2
Dorsett, Y.3
-
50
-
-
0038792101
-
+ regulatory T cells by targeting of antigens to immature dendritic cells
-
+ regulatory T cells by targeting of antigens to immature dendritic cells. Blood 101(12), 4862-4869 (2003).
-
(2003)
Blood
, vol.101
, Issue.12
, pp. 4862-4869
-
-
Mahnke, K.1
Qian, Y.2
Knop, J.3
Enk, A.H.4
-
51
-
-
23744481998
-
Effective induction of naive and recall T cell responses by targeting antigen to human dendritic cells via a humanized antiDC-SIGN antibody
-
Tacken PJ, de Vries IJ, Gijzen K et al. Effective induction of naive and recall T cell responses by targeting antigen to human dendritic cells via a humanized antiDC-SIGN antibody. Blood 106(4), 1278-1285 (2005).
-
(2005)
Blood
, vol.106
, Issue.4
, pp. 1278-1285
-
-
Tacken, P.J.1
De Vries, I.J.2
Gijzen, K.3
-
52
-
-
0036499125
-
The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells
-
Engering A, Geijtenbeek TB, van Vliet SJ et al. The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. J. Immunol. 168(5), 2118-2126 (2002).
-
(2002)
J. Immunol.
, vol.168
, Issue.5
, pp. 2118-2126
-
-
Engering, A.1
Geijtenbeek, T.B.2
Van Vliet, S.J.3
-
53
-
-
10744226740
-
Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs antimelanoma T cell responses via multiple HLA molecules
-
Ramakrishna V, Treml JF, Vitale L et al. Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs antimelanoma T cell responses via multiple HLA molecules. J. Immunol. 172(5), 2845-2852 (2004).
-
(2004)
J. Immunol.
, vol.172
, Issue.5
, pp. 2845-2852
-
-
Ramakrishna, V.1
Treml, J.F.2
Vitale, L.3
-
54
-
-
0036493558
-
In vivo manipulation of dendritic cells to induce therapeutic immunity
-
Merad M, Sugie T, Engleman EG, Fong L. In vivo manipulation of dendritic cells to induce therapeutic immunity. Blood 99(5), 1676-1682 (2002).
-
(2002)
Blood
, vol.99
, Issue.5
, pp. 1676-1682
-
-
Merad, M.1
Sugie, T.2
Engleman, E.G.3
Fong, L.4
-
55
-
-
0034235748
-
Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo
-
Pulendran B, Banchereau J, Burkeholder S et al. Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo. J. Immunol. 165(1), 566-572 (2000).
-
(2000)
J. Immunol.
, vol.165
, Issue.1
, pp. 566-572
-
-
Pulendran, B.1
Banchereau, J.2
Burkeholder, S.3
-
56
-
-
1842486876
-
Induction of potent antitumor immunity by in situ targeting of intratumoral DCs
-
Furumoto K, Soares L, Engleman EG, Merad M. Induction of potent antitumor immunity by in situ targeting of intratumoral DCs. J. Clin. Invest. 113(5), 774-783 (2004). Excellent paper that uses attraction of DCs to tumor sites, in combination with TLR triggering, to induce antitumor responses.
-
(2004)
J. Clin. Invest.
, vol.113
, Issue.5
, pp. 774-783
-
-
Furumoto, K.1
Soares, L.2
Engleman, E.G.3
Merad, M.4
-
57
-
-
14844340568
-
Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate
-
Delamarre L, Pack M, Chang H, Mellman I, Trombetta ES. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science 307(5715), 1630-1634 (2005).
-
(2005)
Science
, vol.307
, Issue.5715
, pp. 1630-1634
-
-
Delamarre, L.1
Pack, M.2
Chang, H.3
Mellman, I.4
Trombetta, E.S.5
-
58
-
-
3442879246
-
CpG oligodeoxynucleotide enhances tumor response to radiation
-
Milas L, Mason KA, Ariga H et al. CpG oligodeoxynucleotide enhances tumor response to radiation. Cancer Res. 64(15), 5074-5077 (2004).
-
(2004)
Cancer Res.
, vol.64
, Issue.15
, pp. 5074-5077
-
-
Milas, L.1
Mason, K.A.2
Ariga, H.3
-
59
-
-
0042024964
-
CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma
-
Weigel BJ, Rodeberg DA, Krieg AM, Blazar BR. CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma. Clin. Cancer Res. 9(8), 3105-3114 (2003).
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.8
, pp. 3105-3114
-
-
Weigel, B.J.1
Rodeberg, D.A.2
Krieg, A.M.3
Blazar, B.R.4
-
60
-
-
0031454570
-
Immunosuppressive effects of apoptotic cells
-
Voll RE, Herrmann M, Roth EA et al. Immunosuppressive effects of apoptotic cells. Nature 390(6658), 350-351 (1997).
-
(1997)
Nature
, vol.390
, Issue.6658
, pp. 350-351
-
-
Voll, R.E.1
Herrmann, M.2
Roth, E.A.3
-
61
-
-
0034614886
-
The induction of tolerance by dendritic cells that have captured apoptotic cells
-
Steinman RM, Turley S, Mellman I, Inaba K. The induction of tolerance by dendritic cells that have captured apoptotic cells. J. Exp. Med. 191(3), 411-416 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, Issue.3
, pp. 411-416
-
-
Steinman, R.M.1
Turley, S.2
Mellman, I.3
Inaba, K.4
-
62
-
-
0034618113
-
A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo
-
Taylor PR, Carugati A, Fadok VA et al. A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo. J. Exp. Med. 192(3), 359-366 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, Issue.3
, pp. 359-366
-
-
Taylor, P.R.1
Carugati, A.2
Fadok, V.A.3
-
63
-
-
0037036369
-
The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway
-
Vabulas RM, Braedel S, Hilf N et al. The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway. J. Biol. Chem. 277(23), 20847-20853 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.23
, pp. 20847-20853
-
-
Vabulas, R.M.1
Braedel, S.2
Hilf, N.3
-
64
-
-
0141998606
-
Molecular identification of a danger signal that alerts the immune system to dying cells
-
Shi Y, Evans JE, Rock KL. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425(6957), 516-521 (2003).
-
(2003)
Nature
, vol.425
, Issue.6957
, pp. 516-521
-
-
Shi, Y.1
Evans, J.E.2
Rock, K.L.3
-
65
-
-
0037117542
-
CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity
-
van Mierlo GJ, den Boer AT, Medema JP et al. CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity. Proc. Natl Acad. Sci. USA 99(8), 5561-5566 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.8
, pp. 5561-5566
-
-
Van Mierlo, G.J.1
Den Boer, A.T.2
Medema, J.P.3
-
66
-
-
17844384773
-
Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: Evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity
-
Salem ML, Kadima AN, Cole DJ, Gillanders WE. Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity. J. Immunother. 28(3), 220-228 (2005).
-
(2005)
J. Immunother.
, vol.28
, Issue.3
, pp. 220-228
-
-
Salem, M.L.1
Kadima, A.N.2
Cole, D.J.3
Gillanders, W.E.4
-
67
-
-
0345447557
-
Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation
-
Nair S, McLaughlin C, Weizer A et al. Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation. J. Immunol. 171(11), 6275-6282 (2003).
-
(2003)
J. Immunol.
, vol.171
, Issue.11
, pp. 6275-6282
-
-
Nair, S.1
McLaughlin, C.2
Weizer, A.3
-
69
-
-
2342558523
-
Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides
-
Krieg AM. Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides. Curr. Oncol. Rep. 6(2), 88-95 (2004).
-
(2004)
Curr. Oncol. Rep.
, vol.6
, Issue.2
, pp. 88-95
-
-
Krieg, A.M.1
-
70
-
-
23944449547
-
Successful combination of local CpG-ODN and radiotherapy in malignant glioma
-
Meng Y, Carpentier AF, Chen L et al. Successful combination of local CpG-ODN and radiotherapy in malignant glioma. Int. J. Cancer 166(6), 992-997 (2005).
-
(2005)
Int. J. Cancer
, vol.166
, Issue.6
, pp. 992-997
-
-
Meng, Y.1
Carpentier, A.F.2
Chen, L.3
-
71
-
-
0034663955
-
Antitumor effects of the mouse chemokine 6Ckine/SLC through angiostatic and immunological mechanisms
-
Vicari AP, Ait-Yahia S, Chemin K et al. Antitumor effects of the mouse chemokine 6Ckine/SLC through angiostatic and immunological mechanisms. J. Immunol. 165(4), 1992-2000 (2000).
-
(2000)
J. Immunol.
, vol.165
, Issue.4
, pp. 1992-2000
-
-
Vicari, A.P.1
Ait-Yahia, S.2
Chemin, K.3
-
72
-
-
0034234623
-
Human endothelial cells express CCR2 and respond to MCP-1: Direct role of MCP-1 in angiogenesis and tumor progression
-
Salcedo R, Ponce ML, Young HA et al. Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood 96(1), 34-40 (2000).
-
(2000)
Blood
, vol.96
, Issue.1
, pp. 34-40
-
-
Salcedo, R.1
Ponce, M.L.2
Young, H.A.3
-
73
-
-
16844379997
-
Immunosuppressive networks in the tumour environment and their therapeutic relevance
-
Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nature Rev. Cancer. 5(4), 263-274 (2005).
-
(2005)
Nature Rev. Cancer
, vol.5
, Issue.4
, pp. 263-274
-
-
Zou, W.1
-
74
-
-
0032709778
-
T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function
-
Sharma S, Stolina M, Lin Y et al. T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function. J. Immunol. 163(9), 5020-5028 (1999).
-
(1999)
J. Immunol.
, vol.163
, Issue.9
, pp. 5020-5028
-
-
Sharma, S.1
Stolina, M.2
Lin, Y.3
-
75
-
-
0037136303
-
Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin-10 receptor antibody
-
Vicari AP, Chiodoni C, Vaure C et al. Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin-10 receptor antibody. J. Exp. Med. 196(4), 541-549 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, Issue.4
, pp. 541-549
-
-
Vicari, A.P.1
Chiodoni, C.2
Vaure, C.3
-
76
-
-
0038273853
-
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
-
Curiel TJ, Wei S, Dong H et al. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nature Med. 9(5), 562-567 (2003).
-
(2003)
Nature Med.
, vol.9
, Issue.5
, pp. 562-567
-
-
Curiel, T.J.1
Wei, S.2
Dong, H.3
-
77
-
-
13844294372
-
PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells
-
Iwai Y, Terawaki S, Honjo T. PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells. Int. Immunol. 17(2), 133-144 (2005).
-
(2005)
Int. Immunol.
, vol.17
, Issue.2
, pp. 133-144
-
-
Iwai, Y.1
Terawaki, S.2
Honjo, T.3
-
78
-
-
0033571785
-
In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas
-
Bell D, Chomarat P, Broyles D et al. In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas. J. Exp. Med. 190(10), 1417-1426 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, Issue.10
, pp. 1417-1426
-
-
Bell, D.1
Chomarat, P.2
Broyles, D.3
-
79
-
-
5044220930
-
IDO expression by dendritic cells: Tolerance and tryptophan catabolism
-
Mellor AL, Munn DH. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nature Rev. Immunol. 4(10), 762-774 (2004).
-
(2004)
Nature Rev. Immunol.
, vol.4
, Issue.10
, pp. 762-774
-
-
Mellor, A.L.1
Munn, D.H.2
-
80
-
-
16844365788
-
+ regulatory T cells in immunological tolerance to self and non-self
-
+ regulatory T cells in immunological tolerance to self and non-self. Nature Immunol. 6(4), 345-352 (2005).
-
(2005)
Nature Immunol.
, vol.6
, Issue.4
, pp. 345-352
-
-
Sakaguchi, S.1
-
81
-
-
21144454780
-
Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response
-
Ercolini AM, Ladle BH, Manning EA et al. Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response. J. Exp. Med. 201(10), 1591-1602 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, Issue.10
, pp. 1591-1602
-
-
Ercolini, A.M.1
Ladle, B.H.2
Manning, E.A.3
-
82
-
-
20244366111
-
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
-
Dudley ME, Wunderlich JR, Yang JC et al. Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J. Clin. Oncol. 23(10), 2346-2357 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.10
, pp. 2346-2357
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Yang, J.C.3
-
83
-
-
0036301503
-
CTLA-4: New insights into its biological function and use in tumor immunotherapy
-
Egen JG, Kuhns MS, Allison JP. CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nature Immunol. 3(7), 611-618 (2002).
-
(2002)
Nature Immunol.
, vol.3
, Issue.7
, pp. 611-618
-
-
Egen, J.G.1
Kuhns, M.S.2
Allison, J.P.3
-
84
-
-
0035903324
-
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
-
Sutmuller RP, van Duivenvoorde LM, van Elsas A et al. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J. Exp. Med. 194(6), 823-832 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, Issue.6
, pp. 823-832
-
-
Sutmuller, R.P.1
Van Duivenvoorde, L.M.2
Van Elsas, A.3
-
85
-
-
0038153907
-
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
-
Phan GQ, Yang JC, Sherry RM et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc. Natl Acad. Sci. USA 100(14), 8372-8377 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.14
, pp. 8372-8377
-
-
Phan, G.Q.1
Yang, J.C.2
Sherry, R.M.3
-
86
-
-
0344341626
-
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
-
Hodi FS, Mihm MC, Soiffer RJ et al. Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc. Natl Acad. Sci. USA 100(8), 4712-4717 (2003). Reports on an excellent human study demonstrating the potential of cytotoxic T-lymphocyte antigen-4 blockade.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.8
, pp. 4712-4717
-
-
Hodi, F.S.1
Mihm, M.C.2
Soiffer, R.J.3
-
87
-
-
0032404099
-
Realization of the therapeutic potential of CTLA-4 blockade in low-dose chemotherapy-treated tumor-bearing mice
-
Mokyr MB, Kalinichenko T, Gorelik L, Bluestone JA. Realization of the therapeutic potential of CTLA-4 blockade in low-dose chemotherapy-treated tumor-bearing mice. Cancer Res. 58(23), 5301-5304 (1998).
-
(1998)
Cancer Res.
, vol.58
, Issue.23
, pp. 5301-5304
-
-
Mokyr, M.B.1
Kalinichenko, T.2
Gorelik, L.3
Bluestone, J.A.4
-
88
-
-
2542603749
-
In situ tumor ablation creates an antigen source for the generation of antitumor immunity
-
den Brok MH, Sutmuller RP, van der Voort R et al. In situ tumor ablation creates an antigen source for the generation of antitumor immunity. Cancer Res. 64(11), 4024-4029 (2004).
-
(2004)
Cancer Res.
, vol.64
, Issue.11
, pp. 4024-4029
-
-
Den Brok, M.H.1
Sutmuller, R.P.2
Van Der Voort, R.3
|