메뉴 건너뛰기




Volumn 12, Issue 11, 2005, Pages 1398-1406

RelA regulates the survival of activated effector CD8 T cells

Author keywords

Cellular activation; Cellular proliferation; Memory; T lymphocytes; Transcription factors

Indexed keywords

CD8 ANTIGEN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROTEIN P50; SYNAPTOTAGMIN; T LYMPHOCYTE RECEPTOR; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR RELA;

EID: 27344439684     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401673     Document Type: Article
Times cited : (17)

References (52)
  • 1
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh S, May MJ and Kopp EB (1998) NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16: 225-260
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 2
    • 0032039076 scopus 로고    scopus 로고
    • Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
    • Zhong H, Voll RE and Ghosh S (1998) Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol. Cell 1: 661-671
    • (1998) Mol. Cell , vol.1 , pp. 661-671
    • Zhong, H.1    Voll, R.E.2    Ghosh, S.3
  • 3
    • 0036203419 scopus 로고    scopus 로고
    • The phosphorylation status of nuclear NF-kappaB determines its association with CBP/p300 or HDAC-1
    • Zhong H, May MJ, Jimi E and Ghosh S (2002) The phosphorylation status of nuclear NF-kappaB determines its association with CBP/p300 or HDAC-1. Mol. Cell 9: 625-636
    • (2002) Mol. Cell , vol.9 , pp. 625-636
    • Zhong, H.1    May, M.J.2    Jimi, E.3    Ghosh, S.4
  • 4
    • 1842526076 scopus 로고    scopus 로고
    • Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B
    • Campbell KJ, Roche S and Perkins ND (2004) Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B. Mol. Cell 13: 893-865
    • (2004) Mol. Cell , vol.13 , pp. 853-865
    • Campbell, K.J.1    Roche, S.2    Perkins, N.D.3
  • 5
    • 0030925372 scopus 로고    scopus 로고
    • Perturbation of the T lymphocyte lineage in trangenic mice expressing a constitutive repressor of nuclear factor (NF)-kB
    • Boothby M, Mora A, Schere D, Brockman J and Ballard D (1997) Perturbation of the T lymphocyte lineage in trangenic mice expressing a constitutive repressor of nuclear factor (NF)-kB. J. Exp. Med. 185: 1897-1907
    • (1997) J. Exp. Med. , vol.185 , pp. 1897-1907
    • Boothby, M.1    Mora, A.2    Schere, D.3    Brockman, J.4    Ballard, D.5
  • 6
    • 0345593715 scopus 로고    scopus 로고
    • In vivo inhibition of NF-kappa B in T-lineage cells leads to a dramatic decrease in cell proliferation and cytokine production and to increased cell apoptosis in response to mitogenic stimuli, but not to abnormal thymopoissis
    • Ferreira V, Sidenius N, Tarantino N, Hubert P, Chatenoud L, Blasi F and Korner M (1999) In vivo inhibition of NF-kappa B in T-lineage cells leads to a dramatic decrease in cell proliferation and cytokine production and to increased cell apoptosis in response to mitogenic stimuli, but not to abnormal thymopoissis. J. Immunol. 162: 6442-6450
    • (1999) J. Immunol. , vol.162 , pp. 6442-6450
    • Ferreira, V.1    Sidenius, N.2    Tarantino, N.3    Hubert, P.4    Chatenoud, L.5    Blasi, F.6    Korner, M.7
  • 7
    • 0037345810 scopus 로고    scopus 로고
    • The survival of antigen-stimulated T cells requires NFkappaB-mediated inhibition of p73 expression
    • Wan YY and DeGregori J (2003) The survival of antigen-stimulated T cells requires NFkappaB-mediated inhibition of p73 expression. Immunity 18: 331-342
    • (2003) Immunity , vol.18 , pp. 331-342
    • Wan, Y.Y.1    DeGregori, J.2
  • 8
  • 9
    • 0037415413 scopus 로고    scopus 로고
    • A critical role for NF-kappaB transcription factors in the development of CD8+ memory-phenotype T cells
    • Hettmann T, Opferman JT, Leiden JM and Ashton-Rickardt PG (2003) A critical role for NF-kappaB transcription factors in the development of CD8+ memory-phenotype T cells. Immunol. Lett. 85: 297-300
    • (2003) Immunol. Lett. , vol.85 , pp. 297-300
    • Hettmann, T.1    Opferman, J.T.2    Leiden, J.M.3    Ashton-Rickardt, P.G.4
  • 10
    • 0033565406 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of caspase-1 and -3
    • Kolenko V, Bloom T, Rayman P, Bukowski R, Hsi E and Finke J (1999) Inhibition of NF-kappa B activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of caspase-1 and -3. J. Immunol. 163: 590-598
    • (1999) J. Immunol. , vol.163 , pp. 590-598
    • Kolenko, V.1    Bloom, T.2    Rayman, P.3    Bukowski, R.4    Hsi, E.5    Finke, J.6
  • 11
    • 0030851835 scopus 로고    scopus 로고
    • Temporal and subunit-specific modulations of the Rel/NF-kappaB transcription factors through CD28 costimulation
    • Kahn-Perles B, Lipcey C, Lecine P, Olive D and Imbert J (1997) Temporal and subunit-specific modulations of the Rel/NF-kappaB transcription factors through CD28 costimulation. J. Biol. Chem. 272: 21774-21783
    • (1997) J. Biol. Chem. , vol.272 , pp. 21774-21783
    • Kahn-Perles, B.1    Lipcey, C.2    Lecine, P.3    Olive, D.4    Imbert, J.5
  • 12
    • 0030999057 scopus 로고    scopus 로고
    • NF-kappa B RelA-deficient lymphocytes: Normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses
    • Doi TS, Takahashi T, Taguchi O, Azuma T and Obata Y (1997) NF-kappa B RelA-deficient lymphocytes: Normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses. J. Exp. Med. 185: 953-961
    • (1997) J. Exp. Med. , vol.185 , pp. 953-961
    • Doi, T.S.1    Takahashi, T.2    Taguchi, O.3    Azuma, T.4    Obata, Y.5
  • 13
    • 0035871841 scopus 로고    scopus 로고
    • NF-kappa B RelA (p65) is essential for TNF-alpha-induced fas expression but dispensable for both TCR-induced expression and activation-induced cell death
    • Zheng Y, Ouaaz F, Bruzzo P, Singh V, Gerondakis S and Beg AA (2001) NF-kappa B RelA (p65) is essential for TNF-alpha-induced fas expression but dispensable for both TCR-induced expression and activation-induced cell death. J. Immunol. 166: 4949-4957
    • (2001) J. Immunol. , vol.166 , pp. 4949-4957
    • Zheng, Y.1    Ouaaz, F.2    Bruzzo, P.3    Singh, V.4    Gerondakis, S.5    Beg, A.A.6
  • 14
    • 0029150389 scopus 로고
    • Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression
    • Kontgen F, Grumont RJ, Strasser A, Metcalf D, Li R, Tarlinton D and Gerondakis 8 (1995) Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes Dev. 9: 1965-1977
    • (1995) Genes Dev. , vol.9 , pp. 1965-1977
    • Kontgen, F.1    Grumont, R.J.2    Strasser, A.3    Metcalf, D.4    Li, R.5    Tarlinton, D.6    Gerondakis, S.7
  • 16
    • 0033023431 scopus 로고    scopus 로고
    • c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function
    • Liou HC, Jin Z, Tumang J, Andjelic S, Smith KA and Liou ML (1999) c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function. Int. Immunol. 11: 361-371
    • (1999) Int. Immunol. , vol.11 , pp. 361-371
    • Liou, H.C.1    Jin, Z.2    Tumang, J.3    Andjelic, S.4    Smith, K.A.5    Liou, M.L.6
  • 17
    • 0344406188 scopus 로고    scopus 로고
    • Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function
    • Zheng Y, Vig M, Lyons J, Van Parijs L and Beg AA (2003) Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function. J. Exp. Med. 197: 861-874
    • (2003) J. Exp. Med. , vol.197 , pp. 861-874
    • Zheng, Y.1    Vig, M.2    Lyons, J.3    Van Parijs, L.4    Beg, A.A.5
  • 18
    • 0034326646 scopus 로고    scopus 로고
    • NF-kappa B is required for the positive selection of CD8+ thymocytes
    • Hettmann T and Leiden JM (2000) NF-kappa B is required for the positive selection of CD8+ thymocytes. J. Immunol. 165: 5004-5010
    • (2000) J. Immunol. , vol.165 , pp. 5004-5010
    • Hettmann, T.1    Leiden, J.M.2
  • 19
    • 0033521663 scopus 로고    scopus 로고
    • An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis
    • Hettmann T, DiDonato J, Karin M and Leiden JM (1999) An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis. J. Exp. Med. 189: 145-158
    • (1999) J. Exp. Med. , vol.189 , pp. 145-158
    • Hettmann, T.1    DiDonato, J.2    Karin, M.3    Leiden, J.M.4
  • 20
    • 0031027505 scopus 로고    scopus 로고
    • Inhibition of bovine endothelial cell activation in vitro by regulated expression of a transdominant inhibitor of NF-kappa B
    • Anrather J, Csizmadia V, Brostjan C, Soares MP, Bach FH and Winkler H (1997) Inhibition of bovine endothelial cell activation in vitro by regulated expression of a transdominant inhibitor of NF-kappa B. J. Clin. Invest. 99: 763-772
    • (1997) J. Clin. Invest. , vol.99 , pp. 763-772
    • Anrather, J.1    Csizmadia, V.2    Brostjan, C.3    Soares, M.P.4    Bach, F.H.5    Winkler, H.6
  • 21
    • 0032212248 scopus 로고    scopus 로고
    • Adenovirus-mediated expression of a dominant negative mutant of p65/RelA inhibits proinflammatory gene expression in endothelial cells without sensitizing to apoptosis
    • Soares MP, Muniappan A, Kaczmarek E, Koziak K, Wrighton CJ, Steinhauslin F, Ferran C, Winkler H, Bach FH and Anrather J (1998) Adenovirus-mediated expression of a dominant negative mutant of p65/RelA inhibits proinflammatory gene expression in endothelial cells without sensitizing to apoptosis. J. Immunol. 161: 4572-4582
    • (1998) J. Immunol. , vol.161 , pp. 4572-4582
    • Soares, M.P.1    Muniappan, A.2    Kaczmarek, E.3    Koziak, K.4    Wrighton, C.J.5    Steinhauslin, F.6    Ferran, C.7    Winkler, H.8    Bach, F.H.9    Anrather, J.10
  • 22
    • 0025943986 scopus 로고
    • The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B
    • Schmitz ML and Baeuerle PA (1991) The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B. EMBO J. 10: 3805-3817
    • (1991) EMBO J. , vol.10 , pp. 3805-3817
    • Schmitz, M.L.1    Baeuerle, P.A.2
  • 23
    • 0026774239 scopus 로고
    • Selection of optimal kappa B/Rel DNA-binding motifs: Interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation
    • Kunsch C, Ruben SM and Rosen CA (1992) Selection of optimal kappa B/Rel DNA-binding motifs: Interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation. Mol. Cell. Biol. 12: 4412-4421
    • (1992) Mol. Cell Biol. , vol.12 , pp. 4412-4421
    • Kunsch, C.1    Ruben, S.M.2    Rosen, C.A.3
  • 24
    • 0033011889 scopus 로고    scopus 로고
    • Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment
    • Chan H, Bartos DP and Owen-Schaub LB (1999) Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment Mol. Cell. Biol. 19: 2098-2108
    • (1999) Mol. Cell Biol. , vol.19 , pp. 2098-2108
    • Chan, H.1    Bartos, D.P.2    Owen-Schaub, L.B.3
  • 25
    • 0033621956 scopus 로고    scopus 로고
    • The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L)
    • Chen C, Edelstein LC and Gelinas C (2000) The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol. Cell. Biol. 20: 2687-2695
    • (2000) Mol. Cell Biol. , vol.20 , pp. 2687-2695
    • Chen, C.1    Edelstein, L.C.2    Gelinas, C.3
  • 27
    • 0027195210 scopus 로고
    • Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by c-REL
    • Cogswell PC, Scheinman RI and Baldwin Jr AS (1993) Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by c-REL. J. Immunol. 150: 2794-2804
    • (1993) J. Immunol. , vol.150 , pp. 2794-2804
    • Cogswell, P.C.1    Scheinman, R.I.2    Baldwin Jr., A.S.3
  • 28
    • 0027410856 scopus 로고
    • The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65
    • Ghosh P, Tan TH, Rice NR, Sica A and Young HA (1993) The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: C-Rel, p50, and p65. Proc. Natl. Acad. Sci. USA 90: 1696-1700
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1696-1700
    • Ghosh, P.1    Tan, T.H.2    Rice, N.R.3    Sica, A.4    Young, H.A.5
  • 29
    • 0033557805 scopus 로고    scopus 로고
    • Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis
    • Grumont RJ, Rourke IJ and Gerondakis S (1999) Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis. Genes Dev. 13: 400-411
    • (1999) Genes Dev. , vol.13 , pp. 400-411
    • Grumont, R.J.1    Rourke, I.J.2    Gerondakis, S.3
  • 30
    • 0034663779 scopus 로고    scopus 로고
    • The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes
    • Khoshnan A, Tindell C, Laux I, Bae D, Bennett B and Nel AE (2000) The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes. J. Immunol. 165: 1743-1754
    • (2000) J. Immunol. , vol.165 , pp. 1743-1754
    • Khoshnan, A.1    Tindell, C.2    Laux, I.3    Bae, D.4    Bennett, B.5    Nel, A.E.6
  • 32
    • 0029166374 scopus 로고
    • Transcriptional regulation of the gene encoding the human C-type lectin leukocyte receptor AIM/CD69 and functional characterization of its tumor necrosis factor-alpha-responsive elements
    • Lopez-Cabrera M, Munoz E, Blazquez MV, Ursa MA, Santis AG and Sanchez-Madrid F (1995) Transcriptional regulation of the gene encoding the human C-type lectin leukocyte receptor AIM/CD69 and functional characterization of its tumor necrosis factor-alpha-responsive elements. J. Biol. Chem. 270: 21545-21551
    • (1995) J. Biol. Chem. , vol.270 , pp. 21545-21551
    • Lopez-Cabrera, M.1    Munoz, E.2    Blazquez, M.V.3    Ursa, M.A.4    Santis, A.G.5    Sanchez-Madrid, F.6
  • 33
    • 0032194170 scopus 로고    scopus 로고
    • Identification of two NF-kappa B sites in mouse CD95 ligand (Fas ligand) promoter. functional analysis in T cell hybridoma
    • Matsui K, Fine A, Zhu B, Marshak-Rothstein A and Ju ST (1998) Identification of two NF-kappa B sites in mouse CD95 ligand (Fas ligand) promoter. functional analysis in T cell hybridoma. J. Immunol. 161: 3469-43473
    • (1998) J. Immunol. , vol.161 , pp. 3469-43473
    • Matsui, K.1    Fine, A.2    Zhu, B.3    Marshak-Rothstein, A.4    Ju, S.T.5
  • 34
    • 0029128116 scopus 로고
    • Activation of IL-2 receptor alpha-chain gene by individual members of the rel oncogene family in association with serum response factor
    • Pierce JW, Jamieson CA, Ross JL and Sen R (1995) Activation of IL-2 receptor alpha-chain gene by individual members of the rel oncogene family in association with serum response factor. J. Immunol. 155: 1972-1980
    • (1995) J. Immunol. , vol.155 , pp. 1972-1980
    • Pierce, J.W.1    Jamieson, C.A.2    Ross, J.L.3    Sen, R.4
  • 35
    • 0025697004 scopus 로고
    • Structural characteristics of the 5′ region of the human ICAM-1 gene
    • Stade BG, Messer G, Riethmuller G and Johnson JP (1990) Structural characteristics of the 5′ region of the human ICAM-1 gene. Immunobiology 182: 79-87
    • (1990) Immunobiology , vol.182 , pp. 79-87
    • Stade, B.G.1    Messer, G.2    Riethmuller, G.3    Johnson, J.P.4
  • 36
    • 0027168948 scopus 로고
    • The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms
    • Scott ML, Fujita T, Liou HC, Nolan GP and Baltimore D (1993) The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms. Genes Dev. 7: 1266-1276
    • (1993) Genes Dev. , vol.7 , pp. 1266-1276
    • Scott, M.L.1    Fujita, T.2    Liou, H.C.3    Nolan, G.P.4    Baltimore, D.5
  • 37
    • 0028485743 scopus 로고
    • The fas antigen is involved in peripheral but not thymic deletion of lymphocytes in T cell receptor transgenic mice
    • Singer GG and Abbas AK (1994) The fas antigen is involved in peripheral but not thymic deletion of lymphocytes in T cell receptor transgenic mice. Immunity 1: 365-371
    • (1994) Immunity , vol.1 , pp. 365-371
    • Singer, G.G.1    Abbas, A.K.2
  • 38
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance
    • Van Parijs L, Ibraghimov A and Abbas AK (1996) The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 4: 321-328
    • (1996) Immunity , vol.4 , pp. 321-328
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 39
    • 0033558215 scopus 로고    scopus 로고
    • The prosurvivall Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis
    • Zong WX, Edelstein LC, Chen C, Bash J and Gelinas C (1999) The prosurvivall Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis. Genes Dev. 13: 382-387
    • (1999) Genes Dev. , vol.13 , pp. 382-387
    • Zong, W.X.1    Edelstein, L.C.2    Chen, C.3    Bash, J.4    Gelinas, C.5
  • 40
    • 0032005484 scopus 로고    scopus 로고
    • The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens
    • Van Parijs L, Peterson DA and Abbas AK (1998) The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity 8: 265-274
    • (1998) Immunity , vol.8 , pp. 265-274
    • Van Parijs, L.1    Peterson, D.A.2    Abbas, A.K.3
  • 42
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
    • Beg AA and Baltimore D (1996) An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274: 782-784
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 43
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kB activation prevents cell death
    • Liu Z-G, Hsu H, Goeddel D and Karin M (1996) Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kB activation prevents cell death. Cell 87: 565-576
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.-G.1    Hsu, H.2    Goeddel, D.3    Karin, M.4
  • 44
    • 0029992609 scopus 로고    scopus 로고
    • Suppression of TNF-alpha-induced apoptosis by NF-kappaB
    • Van Antwerp D, Martin S, Kafri T, Green D and Verma I (1996) Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science 274: 787-789
    • (1996) Science , vol.274 , pp. 787-789
    • Van Antwerp, D.1    Martin, S.2    Kafri, T.3    Green, D.4    Verma, I.5
  • 45
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
    • Wang C, Mayo M and Baldwin Jr A (1996) TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB. Science 274: 784-787
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.1    Mayo, M.2    Baldwin Jr., A.3
  • 46
    • 0141992937 scopus 로고    scopus 로고
    • Regulation of developing B cell survival by RelA-containing NF-kappaB complexes
    • Prendes M, Zheng Y and Beg AA (2003) Regulation of developing B cell survival by RelA-containing NF-kappaB complexes. J. Immunol. 171: 3963-3969
    • (2003) J. Immunol. , vol.171 , pp. 3963-3969
    • Prendes, M.1    Zheng, Y.2    Beg, A.A.3
  • 48
    • 0033427612 scopus 로고    scopus 로고
    • Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells
    • Kurata H, Lee HJ, O'Garra A and Arai N (1999) Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells. Immunity 11: 677-688
    • (1999) Immunity , vol.11 , pp. 677-688
    • Kurata, H.1    Lee, H.J.2    O'Garra, A.3    Arai, N.4
  • 49
    • 0034046944 scopus 로고    scopus 로고
    • Plat-E: An efficient and stable system for transient packaging of retroviruses
    • Morita S, Kojima T and Kitamura T (2000) Plat-E: An efficient and stable system for transient packaging of retroviruses. Gene Ther. 7: 1063-1066
    • (2000) Gene Ther. , vol.7 , pp. 1063-1066
    • Morita, S.1    Kojima, T.2    Kitamura, T.3
  • 50
    • 0035313440 scopus 로고    scopus 로고
    • Regulation of activator protein-1 and NF-kappaB in CD8(+) T cells exposed to peripheral self-antigens
    • Guerder S, Rincon M and Schmitt-Verhulst AM (2001) Regulation of activator protein-1 and NF-kappaB in CD8(+) T cells exposed to peripheral self-antigens. J. Immunol. 166: 4399-4407
    • (2001) J. Immunol. , vol.166 , pp. 4399-4407
    • Guerder, S.1    Rincon, M.2    Schmitt-Verhulst, A.M.3
  • 51
    • 0036236734 scopus 로고    scopus 로고
    • A novel reporter strain to follow Cre-mediated recombination in T and NK cells
    • Wurtz O, Pophillat M, Schmitt-Verhulst AM and Guerder S (2002) A novel reporter strain to follow Cre-mediated recombination in T and NK cells. Genesis 32: 287-292
    • (2002) Genesis , vol.32 , pp. 287-292
    • Wurtz, O.1    Pophillat, M.2    Schmitt-Verhulst, A.M.3    Guerder, S.4
  • 52
    • 0037083665 scopus 로고    scopus 로고
    • Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4(+) T cells
    • Bajenoff M, Wurtz O and Guerder S (2002) Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4(+) T cells. J. Immunol. 168: 1723-1729
    • (2002) J. Immunol. , vol.168 , pp. 1723-1729
    • Bajenoff, M.1    Wurtz, O.2    Guerder, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.