DNA-PKcs-dependent signaling of DNA damage in Dictyostelium discoideum

Current Biology

Volumn 15, Issue 20, 2005, Pages 1880-1885

  Hudson, Jessica J R ^a   Hsu, Duen Wei ^a   Guo, Kunde ^a   Zhukovskaya, Natasha ^b   Liu, Po Hsien ^a   Williams, Jeffrey G ^b   Pears, Catherine J ^a   Lakin, Nicholas D ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; DNA DEPENDENT PROTEIN KINASE; HISTONE; KU ANTIGEN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BIOLOGY; CLUSTER ANALYSIS; COMPARATIVE STUDY; DICTYOSTELIUM; DNA DAMAGE; ENZYME ACTIVE SITE; FLOW CYTOMETRY; GENETICS; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PHYLOGENY; PHYSIOLOGY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, NUCLEAR; BLEOMYCIN; BLOTTING, WESTERN; CATALYTIC DOMAIN; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; DICTYOSTELIUM; DNA DAMAGE; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FLOW CYTOMETRY; HISTONES; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PHYLOGENY; SIGNAL TRANSDUCTION;

DICTYOSTELIUM; DICTYOSTELIUM DISCOIDEUM; VERTEBRATA;

EID: 27144514900     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2005.09.039     Document Type: Article

References (33)

1. S.P. Jackson Sensing and repairing DNA double-strand breaks Carcinogenesis 23 2002 687 696
2. M.R. Lieber, Y. Ma, U. Pannicke, and K. Schwarz Mechanism and regulation of human non-homologous DNA end-joining Nat. Rev. Mol. Cell Biol. 4 2003 712 720
3. T.M. Gottlieb, and S.P. Jackson The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen Cell 72 1993 131 142
4. J. Falck, J. Coates, and S.P. Jackson Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage Nature 434 2005 605 611
5. L. Strmecki, D.M. Greene, and C.J. Pears Developmental decisions in Dictyostelium discoideum Dev. Biol. 284 2005 25 36
6. R.T. Abraham PI 3-kinase related kinases: 'big' players in stress-induced signaling pathways DNA Repair (Amst.) 3 2004 883 887
7. L. Eichinger, J.A. Pachebat, G. Glockner, M.A. Rajandream, R. Sucgang, M. Berriman, J. Song, R. Olsen, K. Szafranski, and Q. Xu The genome of the social amoeba Dictyostelium discoideum Nature 435 2005 43 57
8. R. Bosotti, A. Isacchi, and E.L.L. Sonnhammer FAT: a novel domain in PIK-related kinases Trends Biochem. Sci. 25 2000 225 227
9. C.T. Keith, and S.L. Schreiber PIK Related Kinases DNA Repair, Recombination, and Cell Cycle Checkpoints Science 270 1995 50 51
10. D.W. Chan, B.P. Chen, S. Prithivirajsingh, A. Kurimasa, M.D. Story, J. Qin, and D.J. Chen Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks Genes Dev. 16 2002 2333 2338
11. P. Douglas, G.P. Sapkota, N. Morrice, Y. Yu, A.A. Goodarzi, D. Merkle, K. Meek, D.R. Alessi, and S.P. Lees-Miller Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase Biochem. J. 368 2002 243 251
12. S.J. Boulton, and S.P. Jackson Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double-strand break rejoining and in telomeric maintenance Nucleic Acids Res. 24 1996 4639 4648
13. S.J. Boulton, and S.P. Jackson Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways EMBO J. 15 1996 5093 5103
14. C.J. Weijer, G. Duschl, and C.N. David A revision of the Dictyostelium discoideum cell cycle J. Cell Sci. 70 1984 111 131
15. J.E. Haber Partners and pathways - repairing a double-strand break Trends Genet. 16 2000 259 264
16. G. Chen, G. Shaulsky, and A. Kuspa Tissue-specific G1-phase cell-cycle arrest prior to terminal differentiation in Dictyostelium Development 131 2004 2619 2630
17. J.A. Downs, and S.P. Jackson Cancer: protective packaging for DNA Nature 424 2003 732 734
18. R.A. Deering, M.S. Smith, B.K. Thompson, and A.C. Adolf Gamma-ray-resistant and -sensitive strains of slime mold (Dictyostelium discoideum) Radiat. Res. 43 1970 711 728
19. J.N. Sarkaria, E.C. Busby, R.S. Tibbetts, P. Roos, Y. Taya, L.M. Karnitz, and R.T. Abraham Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine Cancer Res. 59 1999 4375 4382
20. W.D. Block, D. Merkle, K. Meek, and S.P. Lees-Miller Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine Nucleic Acids Res. 32 2004 1967 1972
21. A.S. Dore, A.C. Drake, S.C. Brewerton, and T.L. Blundell Identification of DNA-PK in the arthropods. Evidence for the ancient ancestry of vertebrate non-homologous end-joining DNA Repair (Amst.) 3 2004 33 41
22. R.A. Deering Dictyostelium discoideum: a gamma-ray resistant organism Science 162 1968 1289 1290
23. T. Tsuzuki, Y. Fujii, K. Sakumi, Y. Tominaga, K. Nakao, M. Sekiguchi, A. Matsushiro, Y. Yoshimura, and T. Morita Targeted disruption of the Rad51 gene leads to lethality in embryonic mice Proc. Natl. Acad. Sci. USA 93 1996 6236 6240
24. G.B. Luo, M.S. Yao, C.F. Bender, M. Mills, A.R. Bladl, A. Bradley, and J.H.J. Petrini Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation Proc. Natl. Acad. Sci. USA 96 1999 7376 7381
25. J. Zhu, S. Petersen, L. Tessarollo, and A. Nussenzweig Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice Curr. Biol. 11 2001 105 109
26. Y. Yamaguchi-Iwai, E. Sonoda, M.S. Sasaki, C. Morrison, T. Haraguchi, Y. Hiraoka, Y.M. Yamashita, T. Yagi, M. Takata, and C. Price Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells EMBO J. 18 1999 6619 6629
27. M. Takata, M.S. Sasaki, E. Sonoda, C. Morrison, M. Hashimoto, H. Utsumi, Y. Yamaguchi-Iwai, A. Shinohara, and S. Takeda Homologous recombination and non homologous end joining pathways of DNA double strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells EMBO J. 17 1998 5497 5508
28. M.G. Ferreira, and J.P. Cooper Two modes of DNA double-strand break repair are reciprocally regulated through the fission yeast cell cycle Genes Dev. 18 2004 2249 2254
29. E. Karathanasis, and T.E. Wilson Enhancement of Saccharomyces cerevisiae end-joining efficiency by cell growth stage but not by impairment of recombination Genetics 161 2002 1015 1027
30. J. King, and R.H. Insall Parasexual genetics of Dictyostelium gene disruptions: identification of a ras pathway using diploids BMC Genet. 4 2003 12
31. J. Faix, L. Kreppel, G. Shaulsky, M. Schleicher, and A.R. Kimmel A rapid and efficient method to generate multiple gene disruptions in Dictyostelium discoideum using a single selectable marker and the Cre-loxP system Nucleic Acids Res. 32 2004 e143
32. T. Stiff, M. O'Driscoll, N. Rief, K. Iwabuchi, M. Lobrich, and P.A. Jeggo ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation Cancer Res. 64 2004 2390 2396
33. E. Riballo, M. Kuhne, N. Rief, A. Doherty, G.C. Smith, M.J. Recio, C. Reis, K. Dahm, A. Fricke, and A. Krempler A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci Mol. Cell 16 2004 715 724