The role of the ubiquitin-proteasome system in ER quality control

Essays in Biochemistry

Volumn 41, Issue , 2005, Pages 99-112

  Ye, Yihong ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA;

EID: 27144478935     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/bse0410099     Document Type: Review

References (45)

1. Ozcan, U., Cao, Q., Yilmaz, E., Lee, A.H., Iwakoshi, N.N., Ozdelen, E., Tuncman, G., Gorgun, C., Glimcher, L.H. & Hotamisligil, G.S. (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306, 457-461
2. Tsai, B., Ye, Y. & Rapoport, T.A. (2002) Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nat. Rev. Mol. Cell Biol. 3, 246-255
3. Kostova, Z. & Wolf, D.H. (2003) For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection. EMBO J. 22, 2309-2317
4. Brodsky, J.L. & McCracken, A.A. (1999) ER protein quality control and proteasome-mediated protein degradation. Semin. Cell Dev. Biol. 10, 507-513
5. Tortorella, D., Gewurz, B.E., Furman, M.H., Schust, D.J. & Ploegh, H.L. (2000) Viral subversion of the immune system. Annu. Rev. Immunol. 18, 861-926
6. Sommer, T. & Jentsch, S. (1993) A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum. Nature (London) 365, 176-179
7. Hiller, M.M., Finger, A., Schweiger, M. & Wolf, D.H. (1996) ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway. Science 273, 1725-1728
8. Friedlander, R., Jarosch, E., Urban, J., Volkwein, C. & Sommer, T. (2000) A regulatory link between ER-associated protein degradation and the unfolded-protein response. Nat. Cell Biol. 2, 379-384
9. Biederer, T., Volkwein, C. & Sommer, T. (1997) Role of Cue1p in ubiquitination and degradation at the ER surface. Science 278, 1806-1809
10. Biederer, T., Volkwein, C. & Sommer, T. (1996) Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway. EMBO J. 15, 2069-2076
11. Bays, N.W., Gardner, R.G., Seelig, L.P., Joazeiro, C.A. & Hampton, R.Y. (2001) Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation. Nat. Cell Biol. 3, 24-29
12. Tiwari, S. & Weissman, A.M. (2001) Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits. Involvement of ER-associated ubiquitin-conjugating enzymes (E2s). J. Biol. Chem. 276, 16193-16200
13. Lenk, U., Yu, H., Walter, J., Gelman, M.S., Hartmann, E., Kopito, R.R. & Sommer, T. (2002) A role for mammalian Ubc6 homologues in ER-associated protein degradation. J. Cell Sci. 115, 3007-3014
14. Swanson, R., Locher, M. & Hochstrasser, M. (2001) A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matα2 repressor degradation. Genes Dev. 15, 2660-2674
15. Vashist, S. & Ng, D.T. (2004) Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control. J. Cell Biol. 165, 41-52
16. Haynes, C.M., Caldwell, S. & Cooper, A.A. (2002) An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport. J. Cell. Biol. 158, 91-101
17. Kikkert, M., Doolman, R., Dai, M., Avner, R., Hassink, G., van Voorden, S., Thanedar, S., Roitelman, J., Chau, V. & Wiertz, E. (2004) Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum. J. Biol. Chem. 279, 3525-3534
18. Fang, S., Ferrone, M., Yang, C., Jensen, J.P., Tiwari, S. & Weissman, A.M. (2001) The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum. Proc. Natl. Acad. Sci. U.S.A 98, 14422-14427
19. Meacham, G.C., Patterson, C., Zhang, W., Younger, J.M. & Cyr, D.M. (2001) The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation. Nat. Cell Biol. 3, 100-105
20. Imai, Y., Soda, M., Inoue, H., Hattori, N., Mizuno, Y. & Takahashi, R. (2001) An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 105, 891-902
21. Yoshida, Y., Chiba, T., Tokunaga, F., Kawasaki, H., Iwai, K., Suzuki, T., Ito, Y., Matsuoka, K., Yoshida, M., Tanaka, K. & Tai, T. (2002) E3 ubiquitin ligase that recognizes sugar chains. Nature (London) 418, 438-442
22. Yoshida, Y., Tokunaga, F., Chiba, T., Iwai, K., Tanaka, K. & Tai, T. (2003) Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains. J. Biol. Chem. 278, 43877-43884
23. Flierman, D., Ye, Y., Dai, M., Chau, V. & Rapoport, T.A. (2003) Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane. J. Biol. Chem. 278, 34774-34782
24. Woodman, P.G. (2003) p97, a protein coping with multiple identities. J. Cell Sci. 116, 4283-4290
25. Wang, Q., Song, C. & Li, C.C. (2004) Molecular perspectives on p97-VCP: progress in understanding its structure and diverse biological functions. J. Struct. Biol. 146, 44-57
26. Bays, N.W. & Hampton, R.Y. (2002) Cdc48-Ufd1-Np14: stuck in the middle with Ub. Curr. Biol. 12, R366-R371
27. Ye, Y., Meyer, H.H. & Rapoport, T.A. (2001) The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature (London) 414, 652-656
28. Jarosch, E., Taxis, C., Volkwein, C., Bordallo, J., Finley, D., Wolf, D.H. & Sommer, T. (2002) Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nat. Cell Biol. 4, 134-139
29. Bays, N.W., Wilhovsky, S.K., Goradia, A., Hodgkiss-Harlow, K. & Hampton, R.Y. (2001) HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Mol. Biol. Cell 12, 4114-4128
30. Zhong, X., Shen, Y., Ballar, P., Apostolou, A., Agami, R. & Fang, S. (2004) AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation. J. Biol. Chem. 279, 45676-45684
31. Song, C., Wang, Q. & Li, C.C. (2003) ATPase activity of p97-valosin-containing protein (VCP). D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activity. J. Biol. Chem. 278, 3648-3655
32. Ye, Y., Meyer, H.H. & Rapoport, T.A. (2003) Function of the p97-Ufd1-Np14 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J. Cell Biol. 162, 71-84
33. Hattendorf, D.A. & Lindquist, S.L. (2002) Cooperative kinetics of both Hsp104 ATPase domains and interdomain communication revealed by AAA sensor-1 mutants. EMBO J. 21, 12-21
34. Dai, R.M. & Li, C.C. (2001) Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation. Nat. Cell Biol. 3, 740-744
35. Rape, M., Hoppe, T., Gorr, I., Kalocay, M., Richly, H. & Jentsch, S. (2001) Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone. Cell 107, 667-677
36. Meyer, H.H., Wang, Y. & Warren, G. (2002) Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Np14. EMBO J. 21, 5645-5652
37. Zhang, X., Shaw, A., Bates, P.A., Newman, R.H., Gowen, B., Orlova, E., Gorman, M.A., Kondo, H., Dokurno, P., Lally, J., Leonard, G., Meyer, H., van Heel, M. & Freemont, P.S. (2000) Structure of the AAA ATPase p97. Mol. Cell 6, 1473-1484
38. DeLaBarre, B. & Brunger, A.T. (2003) Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains. Nat. Struct. Biol. 10, 856-863
39. Pickart, C.M. & Cohen, R.E. (2004) Proteasomes and their kin: proteases in the machine age. Nat. Rev. Mol. Cell Biol. 5, 177-187
40. Wang, Y., Satoh, A., Warren, G. & Meyer, H.H. (2004) VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments. J. Cell Biol. 164, 973-978
41. Weibezahn, J., Tessarz, P., Schlieker, C., Zahn, R., Maglica, Z., Lee, S., Zentgraf, H., Weber-Ban, E.U., Dougan, D.A., Tsai, F.T. et al. (2004) Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of CIpB. Cell 119, 653-665
42. Ye, Y., Shibata, Y., Yun, C., Ron, D. & Rapoport, T.A. (2004) A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature (London) 429, 841-847
43. Knop, M., Finger, A., Braun, T., Hellmuth, K. & Wolf, D.H. (1996) Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast. EMBO J. 15, 753-763
44. Lilley, B.N. & Ploegh, H.L. (2004) A membrane protein required for dislocation of misfolded proteins from the ER. Nature (London) 429, 834-840
45. Gao, Y., Feng, H.C., Walder, K., Bolton, K., Sunderland, T., Bishara, N., Quick, M., Kantham, L. & Collier, G.R. (2004) Regulation of the selenoprotein SelS by glucose deprivation and endoplasmic reticulum stress - SelS is a novel glucose-regulated protein. FEBS Lett. 563, 185-190