The C-terminal domain of glutamate receptor subunit 1 is a target for calpain-mediated proteolysis

Neuroscience

Volumn 73, Issue 4, 1996, Pages 903-906

  Bi, X ^a   Chang, V ^a   Molnar, E ^b   McIlhinney, R A J ^b   Baudry, M ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

calpain; glutamate receptors; neurodegeneration; plasticity

Indexed keywords

AMPA RECEPTOR; CALPAIN; CALPASTATIN; EXCITATORY AMINO ACID RECEPTOR; GLUTAMATE RECEPTOR; ION CHANNEL; RECEPTOR SUBUNIT;

ALTERNATIVE RNA SPLICING; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; NERVE CELL PLASTICITY; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; RAT; SYNAPTIC TRANSMISSION;

EID: 0029946108     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(96)00157-1     Document Type: Article

References (18)

1. Baudry M. and Lynch G. (1993) Long-term potentiation: biochemical mechanisms. In Synaptic Plasticity: Molecular and Functional Aspects (eds Baudry M. and Davis J. L.), pp. 87-116. MIT Press Cambridge
2. Baudry M. and Massicotte G. (1992) Physiological and pharmacological relationships between long-term potentiation and mammalian memory. Conc. Neurosci. 3, 79-98.
3. Bennett J. A. and Dingledine R. (1995) Topology profile for a glutamate receptor: three transmembrane domains and a channel-lining reentrant membrane loop. Neuron 14, 373-384.
4. Bi X., Chang V., Tocco G. and Baudry M. (1996) Regional distribution and timecourse of calpain activation following kainate-induced seizure activity in adult rat brain. Brain Res. (in press).
5. Bi X., Tocco G. and Baudry M. (1994) Calpain-mediated regulation of AMPA receptors in adult rat brain. NeuroReport 6, 61-64.
6. Croall D. E. and Demartino G. N. (1991) Calcium-activated neutral protease (calpain) system: structure, function, and regulation. Physiol. Rev. 71, 813-847.
7. Hollmann M. and Heinemann S. (1994) Cloned glutamate receptors. A. Rev. Neurosci. 17, 31-108.
8. Hollmann M., Maron C. and Heinemann S. (1994) N-Glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1. Neuron 13, 1331-1343.
9. Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
10. MacDonald J. F., Bartlett M. C., Orser B. A., Fletcher E. J., Browning M. D. and Wang L. Y. (1994) Regulation of glutamate receptors by reversible phosphorylation. In Direct and Allosteric Control of Glutamate Receptors (eds Palfreyman M. G., Reynolds I. J. and Skolnick P.), pp. 77-93.
11. Molnar E., Baude A., Richmond S. A., Patel B. P., Somogyi P. and McIlhinney R. A. (1993) Biochemical and immunocytochemical characterization of antipeptide antibodies to a cloned GluR1 glutamate receptor subunit: cellular and subcellular distribution in the rat forebrain. Neuroscience 53, 307-326.
12. Najm I., El-Skaf G., Massicotte G., Vanderklish P., Lynch G. and Baudry M. (1992) Changes in polyamine levels and spectrin degradation following kainate-induced seizure activity: effect of difluoromethylornithine. Expl Neurol. 116, 345-354.
13. Roche K. W., Tingley W. G. and Huganir R. L. (1994) Glutamate receptor phosphorylation and synaptic plasticity. Curr. Opin. Neurol. 4, 383-388.
14. Sasaki T., Kikuchi T., Yumoto N., Yoshimura N. and Murachi T. (1984) Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates. J. biol. Chem. 259, 12,489-12,494.
15. Seeburg P. H. (1993) The molecular biology of mammalian glutamate receptor channels. Trends neurosci. 16, 359-365.
16. Tocco G., Massicotte G., Standley S., Thompson R. F. and Baudry M. (1992) Effect of temperature and calcium on the binding properties of the AMPA receptor in frozen rat brain sections. Eur. J. Neurosci. 4, 1093-1103.
17. Towbin H., Staehelin T. and Gordon J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheet: procedure and some applications. Proc. natn. Acad. Sci. U.S.A. 76, 4350-4354.
18. Wenthold R. J., Yokotani N., Doi K. and Wada K. (1992) Immunochemical characterization of the non-NMDA glutamate receptor using subunit-specific antibodies. J. biol. Chem. 267, 501-507.