Chlortetracycline and demeclocycline inhibit calpains and protect mouse neurons against glutamate toxicity and cerebral ischemia

Journal of Biological Chemistry

Volumn 280, Issue 40, 2005, Pages 33811-33818

  Jiang, Susan X ^a   Lertvorachon, Jittiwud ^a   Hou, Sheng T ^a   Konishi, Yasuo ^a   Webster, Jacqueline ^a   Mealing, Geoff ^a   Brunette, Eric ^a   Tauskela, Joseph ^a   Preston, Edward ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BRAIN; CELLS; CYTOLOGY; ENZYME INHIBITION;

CALPAINS; DEMECLOCYCLINE (DMC); TETRACYCLINES;

NEUROLOGY;

CALCIUM; CALPAIN; CALPAIN I; CALPAIN II; CASPASE; CHLORTETRACYCLINE; DEMECLOCYCLINE; DIZOCILPINE; GLUTAMIC ACID; MINOCYCLINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TETRACYCLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; MICROGLIA; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

ANIMALS; ANTI-BACTERIAL AGENTS; BRAIN ISCHEMIA; CALCIUM; CALPAIN; CELL CULTURE TECHNIQUES; CHLORTETRACYCLINE; DEMECLOCYCLINE; ENZYME INHIBITORS; GLUTAMIC ACID; MICE; MICE, INBRED C57BL; NEURONS; NEUROPROTECTIVE AGENTS; RECEPTORS, N-METHYL-D-ASPARTATE;

ANIMALIA;

EID: 26644447992     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M503113200     Document Type: Article

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