Structural modifications to an N-methyl-D-aspartate receptor antagonist result in large differences in trapping block

Journal of Pharmacology and Experimental Therapeutics

Volumn 297, Issue 3, 2001, Pages 906-914

  Mealing, Geoff A R ^a   Lanthorn, T H ^b   Small, D L ^a   Murray, R J ^b   Mattes, K C ^b   Comas, T M ^a   Morley, P ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AR R15808; AR R26952; LANICEMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN CELL; CONTROLLED STUDY; DRUG SAFETY; DRUG STRUCTURE; ELECTROPHYSIOLOGY; HYDROPHOBICITY; LIPOPHILICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EVOKED POTENTIALS; EXCITATORY AMINO ACID ANTAGONISTS; ION CHANNEL GATING; N-METHYLASPARTATE; NEURONS; PATCH-CLAMP TECHNIQUES; PYRIDINES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034999176     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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