Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis

Developmental Biology

Volumn 286, Issue 2, 2005, Pages 472-482

  Pan, Yonghua ^a   Liu, Zhenyi ^a   Shen, Jie ^b   Kopan, Raphael ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

AER; Limb bud; Msx2 Cre; Notch; Syndactyly

Indexed keywords

GAMMA SECRETASE; MUTANT PROTEIN; NOTCH1 RECEPTOR; PROTEIN; PROTEIN JAGGED2; UNCLASSIFIED DRUG;

ALLELE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ECTODERM; LIMB BUD; LIMB DEVELOPMENT; MESENCHYME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 26644446459     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2005.08.037     Document Type: Article

References (53)

1. H. Akiyama, M.C. Chaboissier, J.F. Martin, A. Schedl, and B. de Crombrugghe The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6 Genes Dev. 16 2002 2813 2828
2. L. Baki, J. Shioi, P. Wen, Z. Shao, A. Schwarzman, M. Gama-Sosa, R. Neve, and N.K. Robakis PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations EMBO J. 23 2004 2586 2596
3. J.R. Barrow, K.R. Thomas, O. Boussadia-Zahui, R. Moore, R. Kemler, M.R. Capecchi, and A.P. McMahon Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge Genes Dev. 17 2003 394 409
4. E. Bober, T. Franz, H.H. Arnold, P. Gruss, and P. Tremblay Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells Development 120 1994 603 612
5. R.A. Conlon, A.G. Reaume, and J. Rossant Notch1 is required for the coordinate segmentation of somites Development 121 1995 1533 1545
6. R. Crowe, J. Zikherman, and L. Niswander Delta-1 negatively regulates the transition from prehypertrophic to hypertrophic chondrocytes during cartilage formation Development 126 1999 987 998
7. A.T. Dudley, M.A. Ros, and C.J. Tabin A re-examination of proximodistal patterning during vertebrate limb development Nature 418 2002 539 544
8. S. Huppert, M.X.G. Ilagan, B. De Strooper, and R. Kopan Analysis of Notch function in presomitic mesoderm suggests a g-secretase-independent role for presenilins in somite differentiation Dev. Cell 8 2005 677 688
9. K.D. Irvine, and T.F. Vogt Dorsal-ventral signaling in limb development Curr. Opin. Cell Biol. 9 1997 867 876
10. R. Jiang, Y. Lan, H.D. Chapman, C. Shawber, C.R. Norton, D.V. Serreze, G. Weinmaster, and T. Gridley Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice Genes Dev. 12 1998 1046 1057
11. D.E. Kang, I.S. Yoon, E. Repetto, E.H. Koo, T. Busse, N. Yermian, and L. Ie Presenilins mediate PI3K/Akt and ERK activation via select signaling receptors: selectivity of PS2 in PDGF signaling J. Biol. Chem. 2005
12. M.Y. Kim, J.H. Park, E.J. Choi, and H.S. Park Presenilin acts as a positive regulator of basal level activity of ERK through the Raf-MEK1 signaling pathway Biochem. Biophys. Res. Commun. 332 2005 609 613
13. R. Kopan, and M.X.G. Ilagan g-secretase: proteasome of the membrane? Nat. Rev., Mol. Cell Biol. 5 2004 7 12
14. R. Kopan, J. Lee, M.H. Lin, A.J. Syder, J. Kesterson, N. Crutchfield, C.R. Li, W. Wu, J. Books, and J.I. Gordon Genetic mosaic analysis indicates that the bulb region of coat hair follicles contains a resident population of several active multipotent epithelial lineage progenitors Dev. Biol. 242 2002 44 57
15. L.T. Krebs, Y.Z. Xue, C.R. Norton, J.R. Shutter, M. Maguire, J.P. Sundberg, D. Gallahan, V. Closson, J. Kitajewski, R. Callahan, G.H. Smith, K.L. Stark, and T. Gridley Notch signaling is essential for vascular morphogenesis in mice Genes Dev. 14 2000 1343 1352
16. L.T. Krebs, Y. Xue, C.R. Norton, J.P. Sundberg, P. Beatus, U. Lendahl, A. Joutel, and T. Gridley Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation Genesis 37 2003 139 143
17. E. Laufer, R. Dahn, O.E. Orozco, C.Y. Yeo, J. Pisenti, D. Henrique, U.K. Abbott, J.F. Fallon, and C. Tabin Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation Nature 386 1997 366 373
18. L. Lei, A. Xu, V.M. Panin, and K.D. Irvine An O-fucose site in the ligand binding domain inhibits Notch activation Development 130 2003 6411 6421
19. M. Lin, and R. Kopan Long-range, nonautonomous effects of activated Notch1 on tissue homeostasis in the nail Dev. Biol. 263 2003 343 359
20. M. Lin, C. Leimeister, M. Gessler, and R. Kopan Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers Development 127 2000 2421 2432
21. Z. Liu, J. Xu, J.S. Colvin, and D.M. Ornitz Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18 Genes Dev. 16 2002 859 869
22. M. Logan, J.F. Martin, A. Nagy, C. Lobe, E.N. Olson, and C.J. Tabin Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer Genesis 33 2002 77 80
23. J.F. Martin, and E.N. Olson Identification of a prx1 limb enhancer Genesis 26 2000 225 229
24. T. Mizutani, Y. Taniguchi, T. Aoki, N. Hashimoto, and T. Honjo Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members Proc. Natl. Acad. Sci. U. S. A. 98 2001 9026 9031
25. A.M. Moon, and M.R. Capecchi Fgf8 is required for outgrowth and patterning of the limbs Nat. Genet. 26 2000 455 459
26. A.M. Moon, A.M. Boulet, and M.R. Capecchi Normal limb development in conditional mutants of Fgf4 Development 127 2000 989 996
27. L.C. Murtaugh, B.Z. Stanger, K.M. Kwan, and D.A. Melton Notch signaling controls multiple steps of pancreatic differentiation Proc. Natl. Acad. Sci. U. S. A. 100 2003 14920 14925
28. A. Myat, D. Henrique, D. Ishhorowicz, and J. Lewis A chick homologue of serrate and its relationship with Notch and Delta homologues during central neurogenesis Dev. Biol. 174 1996 233 247
29. L. Niswander Interplay between the molecular signals that control vertebrate limb development Int. J. Dev. Biol. 46 2002 877 881
30. Y. Pan, M. Lin, X. Tian, H. Cheng, T. Gridley, J. Shen, and R. Kopan g-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis Dev. Cell 7 2004 731 743
31. C. Rodriguezesteban, J.W.R. Schwabe, J. Delapena, B. Foys, B. Eshelman, and J.C.I. Belmonte Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb Nature 386 1997 360 366
32. T. Sakata, H. Sakaguchi, L. Tsuda, A. Higashitani, T. Aigaki, K. Matsuno, and S. Hayashi Drosophila nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation Curr. Biol. 14 2004 2228 2236
33. C.A. Saura, S.Y. Choi, V. Beglopoulos, S. Malkani, D. Zhang, B.S. Rao, S. Chattarji, R.J. Kelleher III, E.R. Kandel, K. Duff, A. Kirkwood, and J. Shen Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration Neuron 42 2004 23 36
34. M.T. Saxena, E.H. Schroeter, J.S. Mumm, and R. Kopan Murine Notch homologs (N 1-4) undergo Presenilin dependent proteolysis J. Biol. Chem. 276 2001 40268 40273
35. E.H. Schroeter, J.A. Kisslinger, and R. Kopan Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain Nature 393 1998 382 386
36. C. Shawber, J. Boulter, C.E. Lindsell, and G. Weinmaster Jagged2: a serrate-like gene expressed during rat embryogenesis Dev. Biol. 180 1996 370 376
37. D.D. Shaye, and I. Greenwald Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans Nature 420 2002 686 690
38. A. Sidow, M.S. Bulotsky, A.W. Kerrebrock, R.T. Bronson, M.J. Daly, M.P. Reeve, T.L. Hawkins, B.W. Birren, R. Jaenisch, and E.S. Lander Serrate2 is disrupted in the mouse limb-development mutant syndactylism Nature 389 1997 722 725
39. X. Sun, M. Lewandoski, E.N. Meyers, Y.H. Liu, R.E. Maxson Jr., and G.R. Martin Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development Nat. Genet. 25 2000 83 86
40. X. Sun, F.V. Mariani, and G.R. Martin Functions of FGF signalling from the apical ectodermal ridge in limb development Nature 418 2002 501 508
41. P.J. Swiatek, C.E. Lindsell, F.F. Del-Amo, G. Weinmaster, and T. Gridley Notch1 is essential for postimplantation development in mice Genes Dev. 8 1994 707 719
42. A.T. Tavares, T. Tsukui, and C.I. Belmonte Evidence that members of the Cut/Cux/CDP family may be involved in AER positioning and polarizing activity during chick limb development Development 127 2000 5133 5144
43. N. Vargesson, K. Patel, J. Lewis, and C. Tickle Expression patterns of Notch1, Serrate1, Serrate2 and Delta1 in tissues of the developing chick limb Mech. Dev. 77 1998 197 199
44. D. Vasiliauskas, and C.D. Stern Patterning the embryonic axis. fgf signaling and how vertebrate embryos measure time Cell 106 2001 133 136
45. D. Vasiliauskas, E. Laufer, and C.D. Stern A role for hairy1 in regulating chick limb bud growth Dev. Biol. 262 2003 94 106
46. M.B. Wilkin, A.M. Carbery, M. Fostier, H. Aslam, S.L. Mazaleyrat, J. Higgs, A. Myat, D.A. Evans, M. Cornell, and M. Baron Regulation of notch endosomal sorting and signaling by Drosophila nedd4 family proteins Curr. Biol. 14 2004 2237 2244
47. M. Wines-Samuelson, M. Handler, and J. Shen Role of presenilin-1 in cortical lamination and survival of Cajal-Retzius neurons Dev. Biol. 277 2005 332 346
48. L. Wolpert, J. Lewis, and D. Summerbell Morphogenesis of the vertebrate limb Ciba Found. Symp. 0 1975 95 130
49. J.D. Wrigley, I. Schurov, E.J. Nunn, A.C. Martin, E.E. Clarke, S. Ellis, T.P. Bonnert, M.S. Shearman, and D. Beher Functional overexpression of gamma-secretase reveals protease independent trafficking functions and a critical role of lipids for protease activity J. Biol. Chem. 2004
50. Y.Z. Xue, X. Gao, C.E. Lindsell, C.R. Norton, B. Chang, C. Hicks, M. Gendron-Maguire, E.B. Rand, G. Weinmaster, and T. Gridley Embryonic lethality and vascular defects in mice lacking the Notch ligand JAGGED1 Hum. Mol. Genet. 8 1999 723 730
51. X. Yang, R. Klein, X. Tian, H.T. Cheng, R. Kopan, and J. Shen Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway Dev. Biol. 269 2004 81 94
52. W. Yuan, L. Zhou, J.H. Chen, J.Y. Wu, Y. Rao, and D.M. Ornitz The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance Dev. Biol. 212 1999 290 306
53. N. Zhang, C.R. Norton, and T. Gridley Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice Genesis 33 2002 21 28