-
1
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
Juliano, R.L. and Ling, V. (1976) A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta, 455, 152-162.
-
(1976)
Biochim. Biophys. Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
2
-
-
0038207541
-
Genetic polymorphisms of the human mdr1 drug transporter
-
Schwab, M., Eichelbaum, M. and Fromm, M.F. (2003) Genetic polymorphisms of the human mdr1 drug transporter. A. Rev. Pharmac. Toxicol., 43, 285-307.
-
(2003)
A. Rev. Pharmac. Toxicol.
, vol.43
, pp. 285-307
-
-
Schwab, M.1
Eichelbaum, M.2
Fromm, M.F.3
-
3
-
-
0032540001
-
HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter
-
Lee, C.G., Gottesman, M.M., Cardarelli, C.O., Ramachandra, M., Jeang, K.T., Ambudkar, S.V., Pastan, I. and Dey, S. (1998) HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter. Biochemistry, 37, 3594-3601.
-
(1998)
Biochemistry
, vol.37
, pp. 3594-3601
-
-
Lee, C.G.1
Gottesman, M.M.2
Cardarelli, C.O.3
Ramachandra, M.4
Jeang, K.T.5
Ambudkar, S.V.6
Pastan, I.7
Dey, S.8
-
4
-
-
18744432281
-
HIV-1 protease inhibitors and the MDR1 multidrug transporter
-
[Editorial.]
-
Lee, C.G. and Gottesman, M.M. (1998) HIV-1 protease inhibitors and the MDR1 multidrug transporter. [Editorial.] J. Clin. Invest., 101, 287-288.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 287-288
-
-
Lee, C.G.1
Gottesman, M.M.2
-
5
-
-
0028920219
-
Interaction of the P-glycoprotein multidrug transporter with peptides and ionophores
-
Sharom, F.J., DiDiodato, G., Yu, X. and Ashbourne, K.J. (1995) Interaction of the P-glycoprotein multidrug transporter with peptides and ionophores. J. Biol. Chem., 270, 10334-10341.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 10334-10341
-
-
Sharom, F.J.1
DiDiodato, G.2
Yu, X.3
Ashbourne, K.J.4
-
6
-
-
0031156390
-
How does P-glycoprotein recognize its substrates?
-
Ueda, K., Taguchi, Y. and Morishima, M. (1997) How does P-glycoprotein recognize its substrates? Semin. Cancer Biol., 8, 151-159.
-
(1997)
Semin. Cancer Biol.
, vol.8
, pp. 151-159
-
-
Ueda, K.1
Taguchi, Y.2
Morishima, M.3
-
7
-
-
0034057157
-
Effect of ABC transporters on HIV-1 infection: Inhibition of virus production by the MDR1 transporter
-
Lee, C.G., Ramachandra, M., Jeang, K.T., Martin, M.A., Pastan, I. and Gottesman, M.M. (2000) Effect of ABC transporters on HIV-1 infection: inhibition of virus production by the MDR1 transporter. FASEB J., 14, 516-522.
-
(2000)
FASEB J.
, vol.14
, pp. 516-522
-
-
Lee, C.G.1
Ramachandra, M.2
Jeang, K.T.3
Martin, M.A.4
Pastan, I.5
Gottesman, M.M.6
-
8
-
-
0034012626
-
P-glycoprotein-overexpressing multidrug-resistant cells are resistant to infection by enveloped viruses that enter via the plasma membrane
-
Raviv, Y., Puri, A. and Blumenthal, R. (2000) P-glycoprotein-overexpressing multidrug-resistant cells are resistant to infection by enveloped viruses that enter via the plasma membrane. FASER J., 14, 511-515.
-
(2000)
FASER J.
, vol.14
, pp. 511-515
-
-
Raviv, Y.1
Puri, A.2
Blumenthal, R.3
-
9
-
-
0029945113
-
What have we learnt thus far from mice with disrupted P-glycoprotein genes?
-
Borst, P. and Schinkel, A.H. (1996) What have we learnt thus far from mice with disrupted P-glycoprotein genes? Eur. J. Cancer, 32A, 985-990.
-
(1996)
Eur. J. Cancer
, vol.32 A
, pp. 985-990
-
-
Borst, P.1
Schinkel, A.H.2
-
10
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
-
Schinkel, A.H., Wagenaar, E., Mol, C.A. and van Deemter, L. (1996) P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J. Clin. Invest., 97, 2517-2524.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Mol, C.A.3
van Deemter, L.4
-
11
-
-
0032129118
-
Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice
-
Lankas, G.R., Wise, L.D., Cartwright, M.E., Pippert, T. and Umbenhauer, D.R. (1998) Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice. Reprod. Toxicol., 12, 457-463.
-
(1998)
Reprod. Toxicol.
, vol.12
, pp. 457-463
-
-
Lankas, G.R.1
Wise, L.D.2
Cartwright, M.E.3
Pippert, T.4
Umbenhauer, D.R.5
-
12
-
-
0036667956
-
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
-
Tang, K., Ngoi, S.M., Gwee, P.C., Chua, J.M.Z., Lee, E.J.D., Chong, S.C. and Lee, C.G.L. (2002) Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations. Pharmacogenetics, 12, 437-450.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 437-450
-
-
Tang, K.1
Ngoi, S.M.2
Gwee, P.C.3
Chua, J.M.Z.4
Lee, E.J.D.5
Chong, S.C.6
Lee, C.G.L.7
-
13
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
Kim, R.B., Leake, B.F., Choo, E.F., Dresser, G.K., Kubba, S.V., Schwarz, U.I., Taylor, A., Xie, H.G., McKinsey, J., Zhou, S. et al. (2001) Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin. Pharmac. Ther., 70, 189-199.
-
(2001)
Clin. Pharmac. Ther.
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
Dresser, G.K.4
Kubba, S.V.5
Schwarz, U.I.6
Taylor, A.7
Xie, H.G.8
McKinsey, J.9
Zhou, S.10
-
14
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer, S., Burk, O., von Richter, O., Arnold, H.P., Brockmoller, J., Johne, A., Cascorbi, I., Gerloff, T., Roots, I., Eichelbaum, M. et al. (2000) Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl Acad. Sci. USA, 97, 3473-3478.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
Cascorbi, I.7
Gerloff, T.8
Roots, I.9
Eichelbaum, M.10
-
15
-
-
0034971274
-
The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells
-
Hitzl, M., Drescher, S., van der Kuip, H., Schaffeler, E., Fischer, J., Schwab, M., Eichelbaum, M. and Fromm, M.F. (2001) The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells. Pharmacogenetics, 11, 293-298.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 293-298
-
-
Hitzl, M.1
Drescher, S.2
van der Kuip, H.3
Schaffeler, E.4
Fischer, J.5
Schwab, M.6
Eichelbaum, M.7
Fromm, M.F.8
-
16
-
-
0037022006
-
Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter I: A pharmacogenetic study
-
Fellay, J., Marzolini, C., Meadon, E., Back, D., Buclin, T., Chave, J., Decosterd, L., Furrer, H., Opravil, M., Pantaleo, G. et al. (2002) Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter I: a pharmacogenetic study. Lancet, 359, 30-36.
-
(2002)
Lancet
, vol.359
, pp. 30-36
-
-
Fellay, J.1
Marzolini, C.2
Meadon, E.3
Back, D.4
Buclin, T.5
Chave, J.6
Decosterd, L.7
Furrer, H.8
Opravil, M.9
Pantaleo, G.10
-
17
-
-
0034997034
-
Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene
-
Tanabe, M., Ieiri, I., Nagata, N., Inoue, K., Ito, S., Kanamori, Y., Takahashi, M., Kurata, Y., Kigawa, J., Higuchi, S. et al. (2001) Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene. J. Pharmac. Exp. Ther., 297, 1137-1143.
-
(2001)
J. Pharmac. Exp. Ther.
, vol.297
, pp. 1137-1143
-
-
Tanabe, M.1
Ieiri, I.2
Nagata, N.3
Inoue, K.4
Ito, S.5
Kanamori, Y.6
Takahashi, M.7
Kurata, Y.8
Kigawa, J.9
Higuchi, S.10
-
18
-
-
0036881077
-
The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol
-
Siegmund, W., Ludwig, K., Giessmann, T., Dazert, P., Schroeder, E., Sperker, B., Warzok, R., Kroemer, H.K. and Cascorbi, I. (2002) The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol. Clin. Pharmac. Ther., 72, 572-583.
-
(2002)
Clin. Pharmac. Ther.
, vol.72
, pp. 572-583
-
-
Siegmund, W.1
Ludwig, K.2
Giessmann, T.3
Dazert, P.4
Schroeder, E.5
Sperker, B.6
Warzok, R.7
Kroemer, H.K.8
Cascorbi, I.9
-
19
-
-
10844238220
-
Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects
-
Moriya, Y., Nakamura, T., Hormouchi, M., Sakaeda, T., Tamura, T., Aoyama, N., Shirakawa, T., Gotoh, A., Fujimoto, S., Matsuo, M. et al. (2002) Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects. Biol. Pharm. Bull., 25, 1356-1359.
-
(2002)
Biol. Pharm. Bull.
, vol.25
, pp. 1356-1359
-
-
Moriya, Y.1
Nakamura, T.2
Hormouchi, M.3
Sakaeda, T.4
Tamura, T.5
Aoyama, N.6
Shirakawa, T.7
Gotoh, A.8
Fujimoto, S.9
Matsuo, M.10
-
20
-
-
18444404305
-
Association of the P-glycoprotein transporter MDR1 (C3435T) polymorphism with the susceptibility to renal epithelial tumors
-
Siegsmund, M., Brinkmann, U., Schaffeler, E., Weirich, G., Schwab, M., Eichelbaum, M., Fritz, P., Burk, O., Decker, J., Alken, P. et al. (2002) Association of the P-glycoprotein transporter MDR1 (C3435T) polymorphism with the susceptibility to renal epithelial tumors. J. Am. Soc. Nephrol., 13, 1847-1854.
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 1847-1854
-
-
Siegsmund, M.1
Brinkmann, U.2
Schaffeler, E.3
Weirich, G.4
Schwab, M.5
Eichelbaum, M.6
Fritz, P.7
Burk, O.8
Decker, J.9
Alken, P.10
-
21
-
-
0035383769
-
MDR1 gene-related clonal selection and P-glycoprotein function and expression in relapsed or refractory acute myeloid leukemia
-
van den Heuvel-Eibrink, M.M., Wiemer, E.A., de Boevere, M.J., van der Holt, B., Vossebeld, P.J., Pieters, R. and Sonneveld, P. (2001) MDR1 gene-related clonal selection and P-glycoprotein function and expression in relapsed or refractory acute myeloid leukemia. Blood, 97, 3605-3611.
-
(2001)
Blood
, vol.97
, pp. 3605-3611
-
-
van den Heuvel-Eibrink, M.M.1
Wiemer, E.A.2
de Boevere, M.J.3
van der Holt, B.4
Vossebeld, P.J.5
Pieters, R.6
Sonneveld, P.7
-
22
-
-
0036082545
-
Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system
-
Kimchi-Sarfaty, C., Gribar, J.J. and Gottesman, M.M. (2002) Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system. Mol. Pharmacol., 62, 1-6.
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 1-6
-
-
Kimchi-Sarfaty, C.1
Gribar, J.J.2
Gottesman, M.M.3
-
23
-
-
0036361009
-
A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated with major depression
-
Roberts, R., Joyce, P., Mulder, R., Begg, E. and Kennedy, M. (2002) A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated with major depression. Pharmacogenomics, 2, 191-196.
-
(2002)
Pharmacogenomics
, vol.2
, pp. 191-196
-
-
Roberts, R.1
Joyce, P.2
Mulder, R.3
Begg, E.4
Kennedy, M.5
-
24
-
-
0034771497
-
MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects
-
Sakaeda, T., Nakamura, T., Horinouchi, M., Kakumoto, M., Ohmoto, N., Sakai, T., Morita, Y., Tamura, T., Aoyama, N., Hirai, M. et al. (2001) MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects. Pharm. Res., 18, 1400-1404.
-
(2001)
Pharm. Res.
, vol.18
, pp. 1400-1404
-
-
Sakaeda, T.1
Nakamura, T.2
Horinouchi, M.3
Kakumoto, M.4
Ohmoto, N.5
Sakai, T.6
Morita, Y.7
Tamura, T.8
Aoyama, N.9
Hirai, M.10
-
25
-
-
0036904332
-
MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males
-
Gerloff, T., Schaefer, M., Johne, A., Oselin, K., Meisel, C., Cascorbi, I. and Roots, I. (2002) MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males. Br. J. Clin. Pharmacol., 54, 610-616.
-
(2002)
Br. J. Clin. Pharmacol.
, vol.54
, pp. 610-616
-
-
Gerloff, T.1
Schaefer, M.2
Johne, A.3
Oselin, K.4
Meisel, C.5
Cascorbi, I.6
Roots, I.7
-
26
-
-
0037159922
-
Allele frequency of three functionally active polymorphisms of the MDR- 1 gene in high-risk HIV-negative and HIV-positive Caucasians
-
Ifergan, I., Bernard, N.F., Bruneau, J., Alary, M., Tsoukas, C.M. and Roger, M. (2002) Allele frequency of three functionally active polymorphisms of the MDR- 1 gene in high-risk HIV-negative and HIV-positive Caucasians. AIDS, 16, 2340-2342.
-
(2002)
AIDS
, vol.16
, pp. 2340-2342
-
-
Ifergan, I.1
Bernard, N.F.2
Bruneau, J.3
Alary, M.4
Tsoukas, C.M.5
Roger, M.6
-
27
-
-
0036881149
-
Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene
-
Johne, A., Kopke, K., Gerloff, T., Mai, I., Rietbrock, S., Meisel, C., Hoffmeyer, S., Kerb, R., Fromm, M.F., Brinkmann, U. et al. (2002) Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene. Clin. Pharmac. Ther., 72, 584-594.
-
(2002)
Clin. Pharmac. Ther.
, vol.72
, pp. 584-594
-
-
Johne, A.1
Kopke, K.2
Gerloff, T.3
Mai, I.4
Rietbrock, S.5
Meisel, C.6
Hoffmeyer, S.7
Kerb, R.8
Fromm, M.F.9
Brinkmann, U.10
-
28
-
-
0035999902
-
MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine
-
Drescher, S., Schaeffeler, E., Hitzl, M., Hofmann, U., Schwab, M., Brinkmann, U., Eichelbaum, M. and Fromm, M.F. (2002) MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine. Br. J. Clin. Pharmac., 53, 526-534.
-
(2002)
Br. J. Clin. Pharmac.
, vol.53
, pp. 526-534
-
-
Drescher, S.1
Schaeffeler, E.2
Hitzl, M.3
Hofmann, U.4
Schwab, M.5
Brinkmann, U.6
Eichelbaum, M.7
Fromm, M.F.8
-
29
-
-
0035752933
-
The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels
-
Kerb, R., Aynacioglu, A.S., Brockmoller, J., Schlagenhaufer, R., Bauer, S., Szekeres, T., Hamwi, A., Fritzer-Szekeres, M., Baumgartner, C., Ongen, H.Z. et al. (2001) The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels. Pharmacogenom. J., 1, 204-210.
-
(2001)
Pharmacogenom. J.
, vol.1
, pp. 204-210
-
-
Kerb, R.1
Aynacioglu, A.S.2
Brockmoller, J.3
Schlagenhaufer, R.4
Bauer, S.5
Szekeres, T.6
Hamwi, A.7
Fritzer-Szekeres, M.8
Baumgartner, C.9
Ongen, H.Z.10
-
30
-
-
0037693831
-
Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms
-
Zheng, H., Webber, S., Zeevi, A., Schuetz, E., Zhang, J., Bowman, P., Boyle, G., Law, Y., Miller, S., Lamba, J. et al. (2003) Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms. Am. J. Transplant., 3, 477-483.
-
(2003)
Am. J. Transplant.
, vol.3
, pp. 477-483
-
-
Zheng, H.1
Webber, S.2
Zeevi, A.3
Schuetz, E.4
Zhang, J.5
Bowman, P.6
Boyle, G.7
Law, Y.8
Miller, S.9
Lamba, J.10
-
31
-
-
0037431040
-
Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1
-
Siddiqui, A., Kerb, R., Weale, M.E., Brinkmann, U., Smith, A., Goldstein, D.B., Wood, N.W. and Sisodiya, S.M. (2003) Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. New Engl. J. Med., 348, 1442-1448.
-
(2003)
New Engl. J. Med.
, vol.348
, pp. 1442-1448
-
-
Siddiqui, A.1
Kerb, R.2
Weale, M.E.3
Brinkmann, U.4
Smith, A.5
Goldstein, D.B.6
Wood, N.W.7
Sisodiya, S.M.8
-
32
-
-
0036729669
-
The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients
-
Zheng, H., Webber, S., Zeevi, A., Schuetz, E., Zhang, J., Lamba, J., Bowman, P. and Burckart, G.J. (2002) The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients. Hum. Immunol., 63, 765-770.
-
(2002)
Hum. Immunol.
, vol.63
, pp. 765-770
-
-
Zheng, H.1
Webber, S.2
Zeevi, A.3
Schuetz, E.4
Zhang, J.5
Lamba, J.6
Bowman, P.7
Burckart, G.J.8
-
33
-
-
0037183584
-
Neurotoxicity induced by tacrolimus after liver transplantation: Relation to genetic polymorphisms of the ABCB1 (MDR1) gene
-
Yamauchi, A., Ieiri, I., Kataoka, Y., Tanabe, M., Nishizaki, T., Oishi, R., Higuchi, S., Otsubo, K. and Sugimachi, K. (2002) Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene. Transplantation, 74, 571-572.
-
(2002)
Transplantation
, vol.74
, pp. 571-572
-
-
Yamauchi, A.1
Ieiri, I.2
Kataoka, Y.3
Tanabe, M.4
Nishizaki, T.5
Oishi, R.6
Higuchi, S.7
Otsubo, K.8
Sugimachi, K.9
-
34
-
-
0038241171
-
Polymorphism in the P-glycoprotein drug transporter MDR1 gene: A possible link between environmental and genetic factors in Parkinson's disease
-
Drozdzik, M., Bialecka, M., Mysliwiec, K., Honczarenko, K., Stankiewicz, J. and Sych, Z. (2003) Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease. Pharmacogenetics, 13, 259-263.
-
(2003)
Pharmacogenetics
, vol.13
, pp. 259-263
-
-
Drozdzik, M.1
Bialecka, M.2
Mysliwiec, K.3
Honczarenko, K.4
Stankiewicz, J.5
Sych, Z.6
-
35
-
-
0037223561
-
Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis
-
Schwab, M., Schaeffeler, E., Marx, C., Fromm, M.F., Kaskas, B., Metzler, J., Stange, E., Herfarth, H., Schoelmerich, J., Gregor, M. et al. (2003) Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis. Gastroenterology, 124, 26-33.
-
(2003)
Gastroenterology
, vol.124
, pp. 26-33
-
-
Schwab, M.1
Schaeffeler, E.2
Marx, C.3
Fromm, M.F.4
Kaskas, B.5
Metzler, J.6
Stange, E.7
Herfarth, H.8
Schoelmerich, J.9
Gregor, M.10
-
36
-
-
18644367631
-
Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease
-
Furuno, T., Landi, M.T., Ceroni, M., Caporaso, N., Bernucci, I., Nappi, G., Martignoni, E., Schaeffeler, E., Eichelbaum, M., Schwab, M. et al. (2002) Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease. Pharmacogenetics, 12, 529-534.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 529-534
-
-
Furuno, T.1
Landi, M.T.2
Ceroni, M.3
Caporaso, N.4
Bernucci, I.5
Nappi, G.6
Martignoni, E.7
Schaeffeler, E.8
Eichelbaum, M.9
Schwab, M.10
-
37
-
-
0036731995
-
MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients
-
Illmer, T., Schuler, U.S., Thiede, C., Schwarz, U.I., Kim, R.B., Gotthard, S., Freund, D., Schakel, U., Ehninger, G. and Schaich, M. (2002) MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients. Cancer Res., 62, 4955-4962.
-
(2002)
Cancer Res.
, vol.62
, pp. 4955-4962
-
-
Illmer, T.1
Schuler, U.S.2
Thiede, C.3
Schwarz, U.I.4
Kim, R.B.5
Gotthard, S.6
Freund, D.7
Schakel, U.8
Ehninger, G.9
Schaich, M.10
-
38
-
-
0036956227
-
Gene-based SNP discovery as part of the Japanese Millennium Genome Project: Identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism
-
Haga, H., Yamada, R., Ohnishi, Y., Nakamura, Y. and Tanaka, T. (2002) Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism. J. Hum. Genet., 47, 605-610.
-
(2002)
J. Hum. Genet.
, vol.47
, pp. 605-610
-
-
Haga, H.1
Yamada, R.2
Ohnishi, Y.3
Nakamura, Y.4
Tanaka, T.5
-
39
-
-
0035103009
-
Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects
-
Ito, S., Ieiri, I., Tanabe, M., Suzuki, A., Higuchi, S. and Otsubo, K. (2001) Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects. Pharmacogenetics, 11, 175-184.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 175-184
-
-
Ito, S.1
Ieiri, I.2
Tanabe, M.3
Suzuki, A.4
Higuchi, S.5
Otsubo, K.6
-
40
-
-
0036906745
-
Haplotype and linkage disequilibrium architecture for human cancer-associated genes
-
Bonnen, P.E., Wang, P.J., Kimmel, M., Chakraborty, R. and Nelson, D.L. (2002) Haplotype and linkage disequilibrium architecture for human cancer-associated genes. Genome Res., 12, 1846-1853.
-
(2002)
Genome Res.
, vol.12
, pp. 1846-1853
-
-
Bonnen, P.E.1
Wang, P.J.2
Kimmel, M.3
Chakraborty, R.4
Nelson, D.L.5
-
41
-
-
0037390308
-
Linkage disequilibrium patterns of the human genome across populations
-
Shifman, S., Kuypers, J., Kokoris, M., Yakir, B. and Darvasi, A. (2003) Linkage disequilibrium patterns of the human genome across populations. Hum. Mol. Genet., 12, 771-776.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 771-776
-
-
Shifman, S.1
Kuypers, J.2
Kokoris, M.3
Yakir, B.4
Darvasi, A.5
-
42
-
-
0036208832
-
Patterns of linkage disequilibrium in the human genome
-
Ardlie, K.G., Kruglyak, L. and Seielstad, M. (2002) Patterns of linkage disequilibrium in the human genome. Nat. Rev. Genet., 3, 299-309.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 299-309
-
-
Ardlie, K.G.1
Kruglyak, L.2
Seielstad, M.3
-
43
-
-
0037167852
-
Detecting recent positive selection in the human genome from haplotype structure
-
Sabeti, P.C., Reich, D.E., Higgins, J.M., Levine, H.Z., Richter, D.J., Schaffner, S.F., Gabriel, S.B., Platko, J.V., Patterson, N.J., McDonald, G.J. et al. (2002) Detecting recent positive selection in the human genome from haplotype structure. Nature, 419, 832-837.
-
(2002)
Nature
, vol.419
, pp. 832-837
-
-
Sabeti, P.C.1
Reich, D.E.2
Higgins, J.M.3
Levine, H.Z.4
Richter, D.J.5
Schaffner, S.F.6
Gabriel, S.B.7
Platko, J.V.8
Patterson, N.J.9
McDonald, G.J.10
-
44
-
-
0028885859
-
A recent common ancestry for human Y chromosomes
-
Hammer, M.F. (1995) A recent common ancestry for human Y chromosomes. Nature, 378, 376-378.
-
(1995)
Nature
, vol.378
, pp. 376-378
-
-
Hammer, M.F.1
-
45
-
-
0034619822
-
Mitochondrial genome variation and the origin of modern humans
-
Ingman, M., Kaessmann, H., Paabo, S. and Gyllensten, U. (2000) Mitochondrial genome variation and the origin of modern humans. Nature, 408, 708-713.
-
(2000)
Nature
, vol.408
, pp. 708-713
-
-
Ingman, M.1
Kaessmann, H.2
Paabo, S.3
Gyllensten, U.4
-
46
-
-
0031470484
-
Neandertal DNA sequences and the origin of modern humans
-
Krings, M., Stone, A., Schmitz, R.W., Krainitzki, H., Stoneking, M. and Paabo, S. (1997) Neandertal DNA sequences and the origin of modern humans. Cell, 90, 19-30.
-
(1997)
Cell
, vol.90
, pp. 19-30
-
-
Krings, M.1
Stone, A.2
Schmitz, R.W.3
Krainitzki, H.4
Stoneking, M.5
Paabo, S.6
-
47
-
-
0035163547
-
Extent and distribution of linkage disequilibrium in three genomic regions
-
Abecasis, G.R., Noguchi, E., Heinzmann, A., Traherne, J.A., Bhattacharyya, S., Leaves, N.I., Anderson, G.G., Zhang, Y., Lench, N.J., Carey, A. et al. (2001) Extent and distribution of linkage disequilibrium in three genomic regions. Am. J. Hum. Genet., 68, 191-197.
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 191-197
-
-
Abecasis, G.R.1
Noguchi, E.2
Heinzmann, A.3
Traherne, J.A.4
Bhattacharyya, S.5
Leaves, N.I.6
Anderson, G.G.7
Zhang, Y.8
Lench, N.J.9
Carey, A.10
-
48
-
-
0033658948
-
Haplotypes at ATM identify coding-sequence variation and indicate a region of extensive linkage disequilibrium
-
Bonnen, P.E., Story, M.D., Ashorn, C.L., Buchholz, T.A., Weil, M.M. and Nelson, D.L. (2000) Haplotypes at ATM identify coding-sequence variation and indicate a region of extensive linkage disequilibrium. Am. J. Hum. Genet., 67, 1437-1451.
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 1437-1451
-
-
Bonnen, P.E.1
Story, M.D.2
Ashorn, C.L.3
Buchholz, T.A.4
Weil, M.M.5
Nelson, D.L.6
-
49
-
-
0035919656
-
Haplotype variation and linkage disequilibrium in 313 human genes
-
Stephens, J.C., Schneider, J.A., Tanguay, D.A., Choi, J., Acharya, T., Stanley, S.F., Jiang, R., Messer, C.J., Chew, A., Han, J.H. et al. (2001) Haplotype variation and linkage disequilibrium in 313 human genes. Science, 293, 489-493.
-
(2001)
Science
, vol.293
, pp. 489-493
-
-
Stephens, J.C.1
Schneider, J.A.2
Tanguay, D.A.3
Choi, J.4
Acharya, T.5
Stanley, S.F.6
Jiang, R.7
Messer, C.J.8
Chew, A.9
Han, J.H.10
-
50
-
-
0037313361
-
Linkage disequilibrium and haplotype diversity in the genes of the renin-angiotensin system: Findings from the family blood pressure program
-
Zhu, X., Yan, D., Cooper, R.S., Luke, A., Ikeda, M.A., Chang, Y.P., Weder, A. and Chakravarti, A. (2003) Linkage disequilibrium and haplotype diversity in the genes of the renin-angiotensin system: findings from the family blood pressure program. Genome Res., 13, 173-181.
-
(2003)
Genome Res.
, vol.13
, pp. 173-181
-
-
Zhu, X.1
Yan, D.2
Cooper, R.S.3
Luke, A.4
Ikeda, M.A.5
Chang, Y.P.6
Weder, A.7
Chakravarti, A.8
-
51
-
-
0035837267
-
Linkage disequilibrium in the human genome
-
Reich, D.E., Cargill, M., Bolk, S., Ireland J., Sabeti, P.C., Richter, D.J., Lavery, T., Kouyoumjian, R., Farhadian, S.F., Ward, R. et al. (2001) Linkage disequilibrium in the human genome. Nature, 411, 199-204.
-
(2001)
Nature
, vol.411
, pp. 199-204
-
-
Reich, D.E.1
Cargill, M.2
Bolk, S.3
Ireland, J.4
Sabeti, P.C.5
Richter, D.J.6
Lavery, T.7
Kouyoumjian, R.8
Farhadian, S.F.9
Ward, R.10
-
52
-
-
3042720631
-
MDR1, the blood-brain-barrier transporter is associated with Parkinson's disease in ethnic chinese
-
in press
-
Lee, C.G.L., Tang, K., Cheung, Y.B., Wong, L.P., Tan, C., Shen, H., Zhao, Y., Pavanni, R., Lee, E.J.D., Wong, M.C. et al. (2004) MDR1, the blood-brain-barrier transporter is associated with Parkinson's disease in ethnic chinese. J. Med. Genet., in press.
-
(2004)
J. Med. Genet.
-
-
Lee, C.G.L.1
Tang, K.2
Cheung, Y.B.3
Wong, L.P.4
Tan, C.5
Shen, H.6
Zhao, Y.7
Pavanni, R.8
Lee, E.J.D.9
Wong, M.C.10
-
53
-
-
0037381013
-
Simultaneous genotyping of seven single-nucleotide polymorphisms in the MDR1 gene by single-tube multiplex minisequencing
-
Gwee, P.C., Tang, K., Chua, J.M., Lee, E.J., Chong, S.S. and Lee, C.G. (2003) Simultaneous genotyping of seven single-nucleotide polymorphisms in the MDR1 gene by single-tube multiplex minisequencing. Clin. Chem., 49, 672-676.
-
(2003)
Clin. Chem.
, vol.49
, pp. 672-676
-
-
Gwee, P.C.1
Tang, K.2
Chua, J.M.3
Lee, E.J.4
Chong, S.S.5
Lee, C.G.6
-
54
-
-
0029130796
-
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
-
Excoffier, L. and Slatkin, M. (1995) Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol. Biol. Evol., 12, 921-927.
-
(1995)
Mol. Biol. Evol.
, vol.12
, pp. 921-927
-
-
Excoffier, L.1
Slatkin, M.2
-
55
-
-
0016160841
-
Annotation: The analysis of variance and the analysis of causes
-
Lewontin, R.C. (1974) Annotation: the analysis of variance and the analysis of causes. Am. J. Hum. Genet., 26, 400-411.
-
(1974)
Am. J. Hum. Genet.
, vol.26
, pp. 400-411
-
-
Lewontin, R.C.1
-
56
-
-
0034977045
-
Linkage disequilibrium in humans: Models and data
-
Pritchard, J.K. and Przeworski, M. (2001) Linkage disequilibrium in humans: models and data. Am. J. Hum. Genet., 69, 1-14.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 1-14
-
-
Pritchard, J.K.1
Przeworski, M.2
-
57
-
-
70350211660
-
Can long-range microsatellite data be used to predict short-range linkage disequilibrium?
-
Schulze, T.G., Chen, Y.S., Akula, N., Hennessy, K., Badner, J.A., McInnis, M.G., DePaulo, J.R., Schumacher, J., Cichon, S., Propping, P. et al. (2002) Can long-range microsatellite data be used to predict short-range linkage disequilibrium? Hum. Mol. Genet., 11, 1363-1372.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1363-1372
-
-
Schulze, T.G.1
Chen, Y.S.2
Akula, N.3
Hennessy, K.4
Badner, J.A.5
McInnis, M.G.6
DePaulo, J.R.7
Schumacher, J.8
Cichon, S.9
Propping, P.10
-
58
-
-
0036184745
-
Generating samples under a Wright-Fisher neutral model of genetic variation
-
Hudson, R.R. (2002) Generating samples under a Wright-Fisher neutral model of genetic variation. Bioinformatics, 18, 337-338.
-
(2002)
Bioinformatics
, vol.18
, pp. 337-338
-
-
Hudson, R.R.1
-
59
-
-
0035865094
-
Comparison of human genetic and sequence-based physical maps
-
Yu, A., Zhao, C., Fan, Y., Jang, W., Mungall, A.J., Deloukas, P., Olsen, A., Doggett, N.A., Ghebranious, N., Broman, K.W. et al. (2001) Comparison of human genetic and sequence-based physical maps. Nature, 409, 951-953.
-
(2001)
Nature
, vol.409
, pp. 951-953
-
-
Yu, A.1
Zhao, C.2
Fan, Y.3
Jang, W.4
Mungall, A.J.5
Deloukas, P.6
Olsen, A.7
Doggett, N.A.8
Ghebranious, N.9
Broman, K.W.10
|