Stereoselectivity of the reduced folate carrier in Caco-2 cells

Chirality

Volumn 17, Issue 8, 2005, Pages 444-449

  Narawa, Tomoya ^a   Shimizu, Rikako ^a   Takano, Shuhei ^a   Tsuda, Yasuyuki ^a   Ono, Kiyoko ^a   Yamada, Hideo ^b   Itoh, Tomoo ^a  

^a KITASATO UNIVERSITY   (Japan)

^b MUSASHINO UNIVERSITY   (Japan)

Author keywords

Amethopterin; Caco 2 cell; Methotrexate; RFC; Stereoselectivity; Transporter

Indexed keywords

AMINOPTERIN; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; FOLIC ACID; METHOTREXATE; PROBENECID; REDUCED FOLATE CARRIER;

ABSORPTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL STRAIN CACO 2; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENANTIOMER; FOLATE METABOLISM; INTESTINE BRUSH BORDER; MATHEMATICAL ANALYSIS; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; RABBIT; STEREOCHEMISTRY;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FOLIC ACID ANTAGONISTS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MEMBRANE TRANSPORT PROTEINS; METHOTREXATE; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 25844444629     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/chir.20184     Document Type: Article

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