Dichlorination of a pyrrolyl-S-carrier protein by FADH2- dependent halogenase PltA during pyoluteorin biosynthesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 39, 2005, Pages 13843-13848

  Dorrestein, Pieter C ^a   Yeh, Ellen ^b   Garneau Tsodikova, Sylvie ^b   Kelleher, Neil L ^a   Walsh, Christopher T ^b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Clorobiocin; Coumermycin; Electrospray ionization Fourier transform MS; Flavin reductase; Pyrrole biosynthesis

Indexed keywords

AROMATIC COMPOUND; CARRIER PROTEIN; CHLORINE DERIVATIVE; FLAVIN REDUCTASE; FLAVINE ADENINE NUCLEOTIDE; GENE PRODUCT; HALOGENASE PLTA; NATURAL PRODUCT; OXIDOREDUCTASE; PROLINE; PROTEIN PLTL; PYOLUTEORIN; PYRROLE DERIVATIVE; PYRROLYL S CARRIER PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOESTER; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CHLORINATION; COVALENT BOND; ELECTROSPRAY MASS SPECTROMETRY; ENZYME MECHANISM; FOURIER TRANSFORM MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN MODIFICATION; REACTION ANALYSIS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CARRIER PROTEINS; CHLORINE; FLAVIN-ADENINE DINUCLEOTIDE; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES; PHENOLS; PSEUDOMONAS FLUORESCENS; PYRROLES;

EID: 25444465451     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0506964102     Document Type: Article

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