Identification of a novel PDX-1 binding site in the human insulin gene enhancer

Journal of Biological Chemistry

Volumn 279, Issue 21, 2004, Pages 22228-22235

  Le Lay, John ^a   Matsuoka, Taka Aki ^a,b   Henderson, Eva ^a   Stein, Roland ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; DNA; INSULIN; MASS SPECTROMETRY; MUTAGENESIS; PURIFICATION;

CELL LINES;

GENES;

CIS ACTING ELEMENT; INSULIN; NEUROGENIC DIFFERENTIATION FACTOR; NUCLEOTIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR CDX3; TRANSCRIPTION FACTOR ISL 1; TRANSCRIPTION FACTOR NKX2 2; TRANSCRIPTION FACTOR PAX 4; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BASE PAIRING; BINDING AFFINITY; BINDING SITE; CELL FUNCTION; CONTROLLED STUDY; ENHANCER REGION; GENE ACTIVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; REGULATORY MECHANISM; REGULATORY SEQUENCE; REPORTER GENE; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION;

AMINO ACID MOTIFS; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL NUCLEUS; CHROMATOGRAPHY; CONSERVED SEQUENCE; CRICETINAE; DNA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENHANCER ELEMENTS (GENETICS); HELA CELLS; HOMEODOMAIN PROTEINS; HUMANS; INSULIN; ISLETS OF LANGERHANS; MASS SPECTROMETRY; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NIH 3T3 CELLS; PEPTIDES; PROTEIN BINDING; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION;

ANIMALIA; MAMMALIA; RODENTIA;

EID: 2542497646     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312673200     Document Type: Article

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