Biosynthesis of tetrahydrofolate in plants: Crystal structure of 7,8-dihydroneopterin aldolase from Arabidopsis thaliana reveals a novel adolase class

Journal of Molecular Biology

Volumn 339, Issue 4, 2004, Pages 967-979

  Bauer, Stefanie ^a   Schott, Ann Kathrin ^b   Illarionova, Victoria ^c   Bacher, Adelbert ^b   Huber, Robert ^a   Fischer, Markus ^b  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c INSTITUTE OF BIOPHYSICS   (Russian Federation)

Author keywords

aldolase classes; DHNA, dihydroneopterin aldolase; purin binding; retroaldol reaction; Schiff base; tetrahydrofolate biosynthesis

Indexed keywords

6 HYDROXYMETHYL 7,8 DIHYDROPTERIN; 7,8 DIHYDRONEOPTERIN ALDOLASE; DIHYDRONEOPTERIN TRIPHOSPHATE EPIMERASE; EPIMERASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; METHYL GROUP; MONOMER; POLYPEPTIDE; PTERIDINE; PURINE DERIVATIVE; PYRUVOYLTETRAHYDROPTERIN SYNTHASE; RECOMBINANT PROTEIN; SYNTHETASE; TETRAHYDROFOLIC ACID; TETRAMER; UNCLASSIFIED DRUG; URATE OXIDASE; VITAMIN;

ALPHA HELIX; AMINO ACID SEQUENCE; ARABIDOPSIS; ARTICLE; BACTERIAL STRAIN; BIOSYNTHESIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBUNIT; ESCHERICHIA COLI; GENE EXPRESSION; NONHUMAN; PLANT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; X RAY DIFFRACTION;

ARABIDOPSIS; ARABIDOPSIS THALIANA; ESCHERICHIA COLI;

EID: 2542490230     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.04.034     Document Type: Article

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