Characterization of chloroquine-hematin μ-oxo dimer binding by isothermal titration calorimetry

Biochimica et Biophysica Acta - General Subjects

Volumn 1475, Issue 2, 2000, Pages 133-140

  Vippagunta, Sudha Rani ^a   Dorn, Arnulf ^b   Ridley, Robert G ^b   Vennerstrom, Jonathan L ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Association constant; Chloroquine; Hematin; Hematin oxo dimer; Isothermal titration calorimetry

Indexed keywords

CHLOROQUINE; DIMER; HEMATIN;

ANTIMALARIAL ACTIVITY; ARTICLE; BINDING AFFINITY; CALORIMETRY; DRUG BINDING; ENTHALPY; IONIC STRENGTH; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; STOICHIOMETRY; TITRIMETRY;

ANTIMALARIALS; CALORIMETRY; CHLOROQUINE; DIMERIZATION; HEME; HEMIN; HYDROGEN-ION CONCENTRATION; OSMOLAR CONCENTRATION; SALTS; SPECTROPHOTOMETRY, ULTRAVIOLET; TEMPERATURE;

EID: 0034601111     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4165(00)00058-1     Document Type: Article

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