IL-1β, IFN-γ and TNF-α increase vulnerability of pancreatic beta cells to autoimmune destruction

Journal of Autoimmunity

Volumn 20, Issue 4, 2003, Pages 303-312

  Wachlin, Gerhild ^a   Augstein, Petra ^b   Schröder, Dieter ^a   Kuttler, Beate ^a   Klöting, Ingrid ^a   Heinke, Peter ^b   Schmidt, Siegfried ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b Institut fur Diabetes 'Gerhardt Katsch'   (Germany)

Author keywords

Apoptosis; BB rat; Cytokines; Diabetes; Fas receptor; ICAM 1; IFN ; IL 1 ; Pancreatic cell; TNF

Indexed keywords

FAS ANTIGEN; GAMMA INTERFERON; GLUCOSE; INSULIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; INTERLEUKIN 1; NITRITE; RECOMBINANT GAMMA INTERFERON; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CELL DAMAGE; CELL DESTRUCTION; CELL LEVEL; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE PREDISPOSITION; DNA STRAND BREAKAGE; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; AUTOIMMUNITY; BIOBREEDING RAT; CONGENIC STRAIN; DNA DAMAGE; DRUG EFFECT; IMMUNOLOGY; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; PANCREAS ISLET; SECRETION;

ANIMALS; ANIMALS, CONGENIC; ANTIGENS, CD95; AUTOIMMUNITY; DIABETES MELLITUS, TYPE 1; DNA DAMAGE; INSULIN; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON-GAMMA, RECOMBINANT; INTERLEUKIN-1; ISLETS OF LANGERHANS; NITRITES; RATS; RATS, INBRED BB; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037603320     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-8411(03)00039-8     Document Type: Article

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