Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 34, 2005, Pages 12053-12058

  Holm, Mai Marie ^a,b   Lunn, Marie Louise ^a,c   Traynelis, Stephen F ^b   Kastrup, Jette S ^c   Egebjerg, Jan ^a,d  

^a AARHUS UNIVERSITY   (Denmark)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d H LUNDBECK A S   (Denmark)

Author keywords

2 amino 3 (3 hydroxy 5 tert butyl 4 isoxazolyl)propionic acid (thio ATPA); Crystallization; Desensitization; Domain closure

Indexed keywords

ALPHA AMINO 5 TERT BUTYL 3 HYDROXY 4 ISOXAZOLEPROPIONIC ACID; GLUTAMATE RECEPTOR 2; IONOTROPIC RECEPTOR;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; CHEMICAL REACTION KINETICS; CRYSTALLIZATION; DESENSITIZATION; ELECTROPHYSIOLOGY; LIGAND BINDING; MEDIATOR RELEASE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ANALYSIS;

ALANINE; ALTERNATIVE SPLICING; ANIMALS; BRAIN; CRYSTALLIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; IBOTENIC ACID; KINETICS; MODELS, MOLECULAR; MUTAGENESIS; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, AMPA; SYNAPTIC TRANSMISSION; THIAZOLES; XENOPUS LAEVIS;

EID: 24744467813     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0505522102     Document Type: Article

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