Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist

European Journal of Pharmacology

Volumn 411, Issue 3, 2001, Pages 245-253

  Stensbol, Tine B ^a   Jensen, Henrik S ^b   Nielsen, Birgitte ^a   Johansen, Tommy N ^a   Egebjerg, Jan ^b   Frydenvang, Karla ^a   Krogsgaard Larsen, Povl ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

AMPA (2 amino 3 (3 hydroxy 5 methyl 4 isoxazolyl)propionic acid); AMPA receptor cloned; ATPA (2 amino 3 (5 tert butyl 3 hydroxy 4 isoxazolyl)propionic acid); Chiral chromatography; Cortical wedge preparation; Desensitization; Enantiomer; Kainic acid; Kainic acid receptor cloned; Thio ATPA (2 amino 3 (5 tert butyl 3 hydroxy 4 isothiazolyl)propionic acid)

Indexed keywords

4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; ALPHA AMINO 5 TERT BUTYL 3 HYDROXY 4 ISOTHIAZOLEPROPRIONIC ACID; ALPHA AMINO 5 TERT BUTYL 3 HYDROXY 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMIC ACID; KAINIC ACID; KAINIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHIRAL CHROMATOGRAPHY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ENANTIOMER; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; STEREOCHEMISTRY; XENOPUS LAEVIS;

ALANINE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; EXCITATORY AMINO ACID AGONISTS; KINETICS; MEMBRANE POTENTIALS; MOLECULAR CONFORMATION; OOCYTES; PATCH-CLAMP TECHNIQUES; RATS; RECEPTORS, AMPA; STEREOISOMERISM; THIAZOLES; TRANSCRIPTION, GENETIC; XENOPUS LAEVIS;

EID: 0035847144     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00916-X     Document Type: Article

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