Concomitant deregulation of HIF1α and cell cycle proteins in VHL-mutated renal cell carcinomas

Virchows Archiv

Volumn 447, Issue 3, 2005, Pages 634-642

  Atkins, Derek John ^a   Gingert, Christian ^a   Justenhoven, Christina ^b   Schmahl, Gerd Emil ^a   Bonato, Marcellus Stephanus ^c   Brauch, Hiltrud ^b   Störkel, Stephan ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

^b DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^c MÜNSTER UNIVERSITY OF APPLIED SCIENCES   (Germany)

Author keywords

Cell cycle; HIF1; Renal cell carcinoma; Transcription factors; VHL

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROTEIN P16; PROTEIN P21; PROTEIN P27; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; VON HIPPEL LINDAU PROTEIN; VHL PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CELL CYCLE; CELL DIFFERENTIATION; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; KIDNEY PARENCHYMA; MALE; METHYLATION; MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; UPREGULATION; GENETICS; KIDNEY TUMOR; METABOLISM; MIDDLE AGED; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, RENAL CELL; CELL CYCLE PROTEINS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 24744445823     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-005-1262-y     Document Type: Article

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