Nucleotide binding domains of human CFTR: A structural classification of critical residues and disease-causing mutations

Cellular and Molecular Life Sciences

Volumn 62, Issue 18, 2005, Pages 2112-2123

  Eudes, R ^a   Lehn, P ^b   Ferec C ^b   Mornon, J P ^a   Callebaut, I ^a  

^a UNIVERSITÉ PIERRE ET MARIE CURIE   (France)

^b UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

Author keywords

ABC transporter; CF mutation; CFTR; Critical residue; Cystic fibrosis; Molecular modeling; Nucleotide binding domain; Structural classification

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CHLORIDE CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; CHANNEL GATING; CHLORIDE TRANSPORT; CYSTIC FIBROSIS; MUTATION; NUCLEOTIDE BINDING SITE; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACIDS, AROMATIC; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DIMERIZATION; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEOTIDES; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, PROTEIN;

EID: 24744443019     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-005-5224-y     Document Type: Article

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