-
1
-
-
0033178359
-
The development and therapeutic potential of protein kinase inhibitors
-
Cohen, P. The development and therapeutic potential of protein kinase inhibitors. Curr. Opin. Chem. Biol. 1999, 3, 459-465.
-
(1999)
Curr. Opin. Chem. Biol.
, vol.3
, pp. 459-465
-
-
Cohen, P.1
-
2
-
-
0000266761
-
Stereochemical course of the phospho group transfer catalyzed by cAMP-dependent protein kinase
-
Ho, M.-f.; Bramson, H. N.; Hansen, D. E.; Knowles, J. R.; Kaiser, E. T. Stereochemical course of the phospho group transfer catalyzed by cAMP-dependent protein kinase. J. Am. Chem. Soc. 1988, 110, 2680-2681.
-
(1988)
J. Am. Chem. Soc.
, vol.110
, pp. 2680-2681
-
-
Ho, M.-F.1
Bramson, H.N.2
Hansen, D.E.3
Knowles, J.R.4
Kaiser, E.T.5
-
3
-
-
77956945325
-
-
Boyer, P. D., Ed.; Academic Press: New York
-
Benkovic, S. J.; Schray, K. J. In The Enzymes; Boyer, P. D., Ed.; Academic Press: New York, 1973; Vol. 8, pp 201-238.
-
(1973)
The Enzymes
, vol.8
, pp. 201-238
-
-
Benkovic, S.J.1
Schray, K.J.2
-
4
-
-
0030682398
-
Measurement of a Bronsted nucleophile coefficient and insights into the transition state for a protein tyrosine kinase
-
Kim, K.; Cole, P. A. Measurement of a Bronsted nucleophile coefficient and insights into the transition state for a protein tyrosine kinase. J. Am. Chem. Soc. 1997, 119, 11096-11097.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 11096-11097
-
-
Kim, K.1
Cole, P.A.2
-
5
-
-
0030938253
-
Is there a catalytic base in the active site of cAMP-dependent protein kinase?
-
Zhou, J.; Adams, J. A. Is there a catalytic base in the active site of cAMP-dependent protein kinase? Biochemistry 1997, 36, 2977-2984.
-
(1997)
Biochemistry
, vol.36
, pp. 2977-2984
-
-
Zhou, J.1
Adams, J.A.2
-
6
-
-
0043023392
-
The role of the putative catalytic base in the phosphoryl transfer reaction in a protein kinase: First-principles calculations
-
Valiev, M.; Kawai, R.; Adams, J. A.; Weare, J. H. The Role of the Putative Catalytic Base in the Phosphoryl Transfer Reaction in a Protein Kinase: First-Principles Calculations. J. Am. Chem. Soc. 2003, 125, 9926-9927.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 9926-9927
-
-
Valiev, M.1
Kawai, R.2
Adams, J.A.3
Weare, J.H.4
-
7
-
-
0028773477
-
Three protein kinase structures define a common motif
-
Taylor, S. S.; Radzio-Andzelm, E. Three protein kinase structures define a common motif. Structure 1994, 2, 345-355.
-
(1994)
Structure
, vol.2
, pp. 345-355
-
-
Taylor, S.S.1
Radzio-Andzelm, E.2
-
8
-
-
0034199426
-
Cell communication: The inside story
-
Scott, J. D.; Pawson, T. Cell communication: the inside story. Sci. Am. 2000, 282, 72-79.
-
(2000)
Sci. Am.
, vol.282
, pp. 72-79
-
-
Scott, J.D.1
Pawson, T.2
-
9
-
-
0031457622
-
Signaling through scaffold, anchoring, and adaptor proteins
-
Pawson, T.; Scott, J. D. Signaling Through Scaffold, Anchoring, and Adaptor Proteins, Science 1997, 278, 2075-2080.
-
(1997)
Science
, vol.278
, pp. 2075-2080
-
-
Pawson, T.1
Scott, J.D.2
-
10
-
-
0028331080
-
cAMP-dependent protein kinase: Crystallographic insights into substrate recognition and phosphotransfer
-
Madhusudan; Trafny, E. A.; Xuong, N. H.; Adams, J. A.; Ten Eyck, L. F.; Taylor, S. S.; Sowadski, J. M. cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer. Protein Sci. 1994, 3, 176-187.
-
(1994)
Protein Sci.
, vol.3
, pp. 176-187
-
-
Madhusudan1
Trafny, E.A.2
Xuong, N.H.3
Adams, J.A.4
Ten Eyck, L.F.5
Taylor, S.S.6
Sowadski, J.M.7
-
11
-
-
0023689402
-
CAMP-dependent protein kinase; Prototype for a family of enzymes
-
Taylor, S. S.; Bubis, J.; Toner-Webb, J.; Saraswat, L. D.; First, E. A.; Buechler, J. A.; Knighton, D. R.; Sowadski, J. CAMP-dependent protein kinase; prototype for a family of enzymes. FASEB J. 1988, 2, 2677-2685.
-
(1988)
FASEB J.
, vol.2
, pp. 2677-2685
-
-
Taylor, S.S.1
Bubis, J.2
Toner-Webb, J.3
Saraswat, L.D.4
First, E.A.5
Buechler, J.A.6
Knighton, D.R.7
Sowadski, J.8
-
12
-
-
0026698850
-
Energetic limits of phosphotransfer in the catalytic subunit of cAMP-dependent protein kinase as measured by viscosity experiments
-
Adams, J. A.; Taylor, S. S. Energetic limits of phosphotransfer in the catalytic subunit of cAMP-dependent protein kinase as measured by viscosity experiments. Biochemistry 1992, 31, 8516-8522.
-
(1992)
Biochemistry
, vol.31
, pp. 8516-8522
-
-
Adams, J.A.1
Taylor, S.S.2
-
13
-
-
0030049479
-
Pre-steady-state kinetic analysis of cAMP-dependent protein kinase using rapid quench flow techniques
-
Grant, B. D.; Adams, J. A. Pre-steady-state kinetic analysis of cAMP-dependent protein kinase using rapid quench flow techniques. Biochemistry 1996, 35, 2022-2029.
-
(1996)
Biochemistry
, vol.35
, pp. 2022-2029
-
-
Grant, B.D.1
Adams, J.A.2
-
14
-
-
0033554425
-
Detection of conformational changes along the kinetic pathway of protein kinase A using a catalytic trapping technique
-
Shaffer, J.; Adams, J. A. Detection of conformational changes along the kinetic pathway of protein kinase A using a catalytic trapping technique. Biochemistry 1999, 38, 12072-12079.
-
(1999)
Biochemistry
, vol.38
, pp. 12072-12079
-
-
Shaffer, J.1
Adams, J.A.2
-
15
-
-
0033622319
-
A genetically encoded, fluorescent indicator for cyclic AMP in living cells
-
Zaccolo, M.; De Giorgi, F.; Cho, C. Y.; Feng, L.; Knapp, T.; Neǵulescu, P. A.; Taylor, S. S.; Tsien, R. Y.; Pozzan, T. A genetically encoded, fluorescent indicator for cyclic AMP in living cells. Nat. Cell Biol. 2000, 2, 25-29.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 25-29
-
-
Zaccolo, M.1
De Giorgi, F.2
Cho, C.Y.3
Feng, L.4
Knapp, T.5
Neǵulescu, P.A.6
Taylor, S.S.7
Tsien, R.Y.8
Pozzan, T.9
-
16
-
-
0026484261
-
SH2 and SH3 domains: From structure to function
-
Pawson, T.; Gish, G. D. SH2 and SH3 domains: from structure to function. Cell 1992, 71, 359-362.
-
(1992)
Cell
, vol.71
, pp. 359-362
-
-
Pawson, T.1
Gish, G.D.2
-
17
-
-
0033628016
-
Kinases of the Src family: Structure and functions
-
Tatosyan, A. G.; Mizenina, O. A. Kinases of the Src family: structure and functions. Biochemistry (Moscow) 2000, 65, 49-58.
-
(2000)
Biochemistry (Moscow)
, vol.65
, pp. 49-58
-
-
Tatosyan, A.G.1
Mizenina, O.A.2
-
18
-
-
0035800835
-
Release from tonic inhibition of t cell activation through transient displacement of C-terminal src kinase (Csk) from lipid rafts
-
Torgersen, K. M.; Vang, T.; Abrahamsen, H.; Yaqub, S.; Horejsi, V.; Schraven, B.; Rolstad, B.; Mustelin, T.; Tasken, K. Release from Tonic Inhibition of T Cell Activation through Transient Displacement of C-terminal Src Kinase (Csk) from Lipid Rafts. J. Biol. Chem. 2001, 276, 29313-29318.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29313-29318
-
-
Torgersen, K.M.1
Vang, T.2
Abrahamsen, H.3
Yaqub, S.4
Horejsi, V.5
Schraven, B.6
Rolstad, B.7
Mustelin, T.8
Tasken, K.9
-
19
-
-
0026326821
-
Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
-
Knighton, D. R.; Zheng, J. H.; Ten Eyck, L. F.; Xuong, N. H.; Taylor, S. S.; Sowadski, J. M. Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase [see comments]. Science 1991, 253, 414-420.
-
(1991)
Science
, vol.253
, pp. 414-420
-
-
Knighton, D.R.1
Zheng, J.H.2
Ten Eyck, L.F.3
Xuong, N.H.4
Taylor, S.S.5
Sowadski, J.M.6
-
20
-
-
0032568629
-
Kinetic analyses of mutations in the glycine-rich loop of cAMP-dependent protein kinase
-
Grant, B. D.; Hemmer, W.; Tsigelny, I.; Adams, J. A.; Taylor, S. S. Kinetic analyses of mutations in the glycine-rich loop of cAMP-dependent protein kinase. Biochemistry 1998, 37, 7708-7715.
-
(1998)
Biochemistry
, vol.37
, pp. 7708-7715
-
-
Grant, B.D.1
Hemmer, W.2
Tsigelny, I.3
Adams, J.A.4
Taylor, S.S.5
-
21
-
-
0033784003
-
Catalytic assessment of the glycine-rich loop of the v-Fps oncoprotein using site-directed mutagenesis
-
Hirai, T. J.; Tsigelny, I.; Adams, J. A. Catalytic assessment of the glycine-rich loop of the v-Fps oncoprotein using site-directed mutagenesis. Biochemistry 2000, 39, 13276-13284.
-
(2000)
Biochemistry
, vol.39
, pp. 13276-13284
-
-
Hirai, T.J.1
Tsigelny, I.2
Adams, J.A.3
-
22
-
-
0028898390
-
Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase
-
Adams, J. A.; McGlone, M. L.; Gibson, R.; Taylor, S. S. Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase. Biochemistry 1995, 34, 2447-2454.
-
(1995)
Biochemistry
, vol.34
, pp. 2447-2454
-
-
Adams, J.A.1
McGlone, M.L.2
Gibson, R.3
Taylor, S.S.4
-
23
-
-
0034625161
-
Snapping of the carboxyl terminal tail of the catalytic subunit of PKA onto its core: Characterization of the sites by mutagenesis
-
Batkin, M.; Schvartz, I.; Shaltiel, S. Snapping of the carboxyl terminal tail of the catalytic subunit of PKA onto its core: characterization of the sites by mutagenesis. Biochemistry 2000, 39, 5366-5373.
-
(2000)
Biochemistry
, vol.39
, pp. 5366-5373
-
-
Batkin, M.1
Schvartz, I.2
Shaltiel, S.3
-
24
-
-
0033600568
-
Domain interactions in protein tyrosine kinase Csk
-
Sondhi, D.; Cole, P. A. Domain interactions in protein tyrosine kinase Csk. Biochemistry 1999, 38, 11147-11155.
-
(1999)
Biochemistry
, vol.38
, pp. 11147-11155
-
-
Sondhi, D.1
Cole, P.A.2
-
25
-
-
0033566180
-
Mutations in the N-terminal regulatory region reduce the catalytic activity of Csk, but do not affect its recognition of Src
-
Sun, G.; Budde, R. J. Mutations in the N-terminal regulatory region reduce the catalytic activity of Csk, but do not affect its recognition of Src. Arch. Biochem. Biophys. 1999, 367, 167-172.
-
(1999)
Arch. Biochem. Biophys.
, vol.367
, pp. 167-172
-
-
Sun, G.1
Budde, R.J.2
-
26
-
-
0034703099
-
Transmembrane phosphoprotein Cbp positively regulates the activity of the carboxyl-terminal Src kinase
-
Takeuchi, S.; Takayama, Y.; Ogawa, A.; Tamura, K.; Okada, M. Transmembrane phosphoprotein Cbp positively regulates the activity of the carboxyl-terminal Src kinase. Csk. J. Biol. Chem. 2000, 275, 29183-29186.
-
(2000)
Csk. J. Biol. Chem.
, vol.275
, pp. 29183-29186
-
-
Takeuchi, S.1
Takayama, Y.2
Ogawa, A.3
Tamura, K.4
Okada, M.5
-
27
-
-
0030766163
-
Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analogue
-
Hubbard, S. R. Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analogue. EMBO J. 1997, 16, 5572-5581.
-
(1997)
EMBO J.
, vol.16
, pp. 5572-5581
-
-
Hubbard, S.R.1
-
28
-
-
0029029617
-
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
-
Jeffrey, P. D.; Russo, A. A.; Polyak, K.; Gibbs, E.; Hurwitz, J.; Massague, J.; Pavletich, N. P. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex [see comments]. Nature 1995, 376, 313-320.
-
(1995)
Nature
, vol.376
, pp. 313-320
-
-
Jeffrey, P.D.1
Russo, A.A.2
Polyak, K.3
Gibbs, E.4
Hurwitz, J.5
Massague, J.6
Pavletich, N.P.7
-
29
-
-
0037469146
-
Activation loop phosphorylation and catalysis in protein kinases: Is there functional evidence for the autoinhibitor model?
-
Adams, J. A. Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model? Biochemistry 2003, 42, 601-607.
-
(2003)
Biochemistry
, vol.42
, pp. 601-607
-
-
Adams, J.A.1
-
30
-
-
0020484823
-
Investigation of diffusion-limited rates of chymotrypsin reactions by viscosity variation
-
Brouwer, A. C.; Kirsch, J. F. Investigation of diffusion-limited rates of chymotrypsin reactions by viscosity variation. Biochemistry 1982, 21, 1302-1307.
-
(1982)
Biochemistry
, vol.21
, pp. 1302-1307
-
-
Brouwer, A.C.1
Kirsch, J.F.2
-
31
-
-
0035909107
-
Nucleotide release and associated conformational changes regulate function in the COOH-terminal Src kinase, Csk
-
Shaffer, J.; Sun, G.; Adams, J. A. Nucleotide Release and Associated Conformational Changes Regulate Function in the COOH-Terminal Src Kinase, Csk. Biochemistry 2001, 40, 11149-11155.
-
(2001)
Biochemistry
, vol.40
, pp. 11149-11155
-
-
Shaffer, J.1
Sun, G.2
Adams, J.A.3
-
32
-
-
0031024404
-
Divalent ion effects and insights into the catalytic mechanism of protein tyrosine kinase Csk
-
Grace, M. R.; Walsh, C. T.; Cole, P. A. Divalent ion effects and insights into the catalytic mechanism of protein tyrosine kinase Csk. Biochemistry 1997, 36, 1874-1881.
-
(1997)
Biochemistry
, vol.36
, pp. 1874-1881
-
-
Grace, M.R.1
Walsh, C.T.2
Cole, P.A.3
-
33
-
-
0027429591
-
Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations
-
Zheng, J.; Knighton, D. R.; Xuong, N. H.; Taylor, S. S.; Sowadski, J. M. ; Ten Eyck, L. F. Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations. Protein Sci. 1993, 2, 1559-1573.
-
(1993)
Protein Sci.
, vol.2
, pp. 1559-1573
-
-
Zheng, J.1
Knighton, D.R.2
Xuong, N.H.3
Taylor, S.S.4
Sowadski, J.M.5
Ten Eyck, L.F.6
-
34
-
-
0030866897
-
Activation mechanism of the MAP kinase ERK2 by dual phosphorylation
-
Canagarajah, B. J.; Khokhlatchev, A.; Cobb, M. H.; Goldsmith, E. J. Activation mechanism of the MAP kinase ERK2 by dual phosphorylation. Cell 1997, 90, 859-869.
-
(1997)
Cell
, vol.90
, pp. 859-869
-
-
Canagarajah, B.J.1
Khokhlatchev, A.2
Cobb, M.H.3
Goldsmith, E.J.4
-
35
-
-
0030995603
-
Identification of a partially rate-determining step in the catalytic mechanism of cAMP-dependent protein kinase: A transient kinetic study using stopped-flow fluorescence spectroscopy
-
Lew, J.; Taylor, S. S., Adams, J. A. Identification of a partially rate-determining step in the catalytic mechanism of cAMP-dependent protein kinase: a transient kinetic study using stopped-flow fluorescence spectroscopy. Biochemistry 1997, 36, 6717-6724.
-
(1997)
Biochemistry
, vol.36
, pp. 6717-6724
-
-
Lew, J.1
Taylor, S.S.2
Adams, J.A.3
-
37
-
-
0033609051
-
An ATP-linked structural change in protein kinase A precedes phosphoryl transfer under physiological magnesium concentrations
-
Shaffer, J.; Adams, J. A. An ATP-linked structural change in protein kinase A precedes phosphoryl transfer under physiological magnesium concentrations. Biochemistry 1999, 38, 5572-5581.
-
(1999)
Biochemistry
, vol.38
, pp. 5572-5581
-
-
Shaffer, J.1
Adams, J.A.2
-
38
-
-
0034663983
-
Insights into the HER-2 receptor tyrosine kinase mechanism and substrate specificity using a transient kinetic analysis
-
Jan, A. Y.; Johnson, E. F.; Diamonti, A. J.; Carraway, I. K.; Anderson, K. S. Insights into the HER-2 receptor tyrosine kinase mechanism and substrate specificity using a transient kinetic analysis. Biochemistry 2000, 39, 9786-9803.
-
(2000)
Biochemistry
, vol.39
, pp. 9786-9803
-
-
Jan, A.Y.1
Johnson, E.F.2
Diamonti, A.J.3
Carraway, I.K.4
Anderson, K.S.5
-
39
-
-
0037008011
-
Multiple conformational changes in enzyme catalysis
-
Hammes, G. G. Multiple conformational changes in enzyme catalysis. Biochemistry 2002, 41, 8221-8228.
-
(2002)
Biochemistry
, vol.41
, pp. 8221-8228
-
-
Hammes, G.G.1
-
40
-
-
0035413606
-
Kinetic and Catalytic Mechanisms of Protein Kinases
-
Adams, J. A. Kinetic and Catalytic Mechanisms of Protein Kinases. Chem. Rev. 2001, 101, 2271-2290.
-
(2001)
Chem. Rev.
, vol.101
, pp. 2271-2290
-
-
Adams, J.A.1
-
41
-
-
0032491190
-
Mapping substrate-induced conformational changes in cAMP-dependent protein kinase by protein footprinting
-
Cheng, X.; Shaltiel, S.; Taylor, S. S. Mapping substrate-induced conformational changes in cAMP-dependent protein kinase by protein footprinting. Biochemistry 1998, 37, 14005-14013.
-
(1998)
Biochemistry
, vol.37
, pp. 14005-14013
-
-
Cheng, X.1
Shaltiel, S.2
Taylor, S.S.3
-
42
-
-
0036306530
-
Evidence for an internal entropy contribution to phosphoryl transfer: A study of domain closure, backbone flexibility, and the catalytic cycle of cAMP-dependent protein kinase
-
Li, F.; Gangal, M.; Juliano, C.; Gorfain, E.; Taylor, S. S.; Johnson, D. A. Evidence for an internal entropy contribution to phosphoryl transfer: a study of domain closure, backbone flexibility, and the catalytic cycle of cAMP-dependent protein kinase. J. Mol. Biol. 2002, 315, 459-469.
-
(2002)
J. Mol. Biol.
, vol.315
, pp. 459-469
-
-
Li, F.1
Gangal, M.2
Juliano, C.3
Gorfain, E.4
Taylor, S.S.5
Johnson, D.A.6
-
43
-
-
0035969987
-
Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange
-
Hoofnagle, A. N.; Resing, K. A.; Goldsmith, E. J.; Ahn, N. G. Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange. Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 956-961.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 956-961
-
-
Hoofnagle, A.N.1
Resing, K.A.2
Goldsmith, E.J.3
Ahn, N.G.4
-
44
-
-
0036428762
-
Phosphorylation driven motions in the COOH-terminal Src kinase, Csk, revealed through enhanced hydrogen-deuterium exchange and mass spectrometry (DXMS)
-
Hamuro, Y.; Wong, L.; Shaffer, J.; Kim, J. S.; Stranz, D. D.; Jennings, P. A.; Woods, V. L.; Adams, J. A. Phosphorylation Driven Motions in the COOH-terminal Src Kinase, Csk, Revealed Through Enhanced Hydrogen-Deuterium Exchange and Mass Spectrometry (DXMS). J. Mol. Biol. 2002, 323, 871-881.
-
(2002)
J. Mol. Biol.
, vol.323
, pp. 871-881
-
-
Hamuro, Y.1
Wong, L.2
Shaffer, J.3
Kim, J.S.4
Stranz, D.D.5
Jennings, P.A.6
Woods, V.L.7
Adams, J.A.8
-
45
-
-
0034710950
-
Binding sites in Escherichia coli dihydrofolate reductase communicate by modulating the conformational ensemble
-
Pan, H.; Lee, J. C.; Hilser, V. J. Binding sites in Escherichia coli dihydrofolate reductase communicate by modulating the conformational ensemble. Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 12020-12025.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 12020-12025
-
-
Pan, H.1
Lee, J.C.2
Hilser, V.J.3
-
46
-
-
0032489443
-
Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane
-
Okamoto, T.; Schlegel, A.; Scherer, P. E., Lisanti, M. P. Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane. J. Biol. Chem. 1998, 273, 5419-5422.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5419-5422
-
-
Okamoto, T.1
Schlegel, A.2
Scherer, P.E.3
Lisanti, M.P.4
-
47
-
-
0034728352
-
Kinetic mechanism of the p38-alpha MAP kinase: Phosphoryl transfer to synthetic peptides
-
Chen, G.; Porter, M. D.; Bristol, J. R.; Fitzgibbon, M. J.; Pazhanisamy, S. Kinetic mechanism of the p38-alpha MAP kinase: phosphoryl transfer to synthetic peptides. Biochemistry 2000, 39, 2079-2087.
-
(2000)
Biochemistry
, vol.39
, pp. 2079-2087
-
-
Chen, G.1
Porter, M.D.2
Bristol, J.R.3
Fitzgibbon, M.J.4
Pazhanisamy, S.5
-
48
-
-
0035910759
-
Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor
-
Vang, T.; Torgersen, K. M.; Sundvold, V.; Saxena, M.; Levy, F. O.; Skalhegg, B. S.; Hansson, V.; Mustelin, T.; Tasken, K. Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor. J. Exp. Med. 2001, 193, 497-507.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 497-507
-
-
Vang, T.1
Torgersen, K.M.2
Sundvold, V.3
Saxena, M.4
Levy, F.O.5
Skalhegg, B.S.6
Hansson, V.7
Mustelin, T.8
Tasken, K.9
-
49
-
-
13344282755
-
Rate-determining steps for tyrosine phosphorylation by the kinase domain of v-fps
-
Wang, C.; Lee, T. R.; Lawrence, D. S.; Adams, J. A. Rate-determining steps for tyrosine phosphorylation by the kinase domain of v-fps. Biochemistry 1996, 35, 1533-1539.
-
(1996)
Biochemistry
, vol.35
, pp. 1533-1539
-
-
Wang, C.1
Lee, T.R.2
Lawrence, D.S.3
Adams, J.A.4
-
50
-
-
0037031243
-
Mechanistic Insights into Sky1p, a Yeast Homologue of the Mammalian SR Protein Kinases
-
Aubol, B. E.; Nolen, B.; Vu, D.; Ghosh, G.; Adams, J. A. Mechanistic Insights into Sky1p, a Yeast Homologue of the Mammalian SR Protein Kinases. Biochemistry 2002, 41, 10002-10009.
-
(2002)
Biochemistry
, vol.41
, pp. 10002-10009
-
-
Aubol, B.E.1
Nolen, B.2
Vu, D.3
Ghosh, G.4
Adams, J.A.5
-
51
-
-
0035895366
-
Activation of the Insulin Receptor's Kinase Domain Changes the Rate-Determining Step of Substrate Phosphorylation
-
Ablooglu, A. J.; Kohanski, R. A. Activation of the Insulin Receptor's Kinase Domain Changes the Rate-Determining Step of Substrate Phosphorylation. Biochemistry 2001, 40, 504-513.
-
(2001)
Biochemistry
, vol.40
, pp. 504-513
-
-
Ablooglu, A.J.1
Kohanski, R.A.2
-
52
-
-
0035808444
-
Kinetic basis for activation of CDK2/cyclin a by phosphorylation
-
Hagopian, J. C.; Kirtley, M. P.; Stevenson, L. M.; Gergis, R. M.; Russo, A. A.; Pavletich, N. P.; Parsons, S. M.; Lew, J. Kinetic Basis for Activation of CDK2/Cyclin A by Phosphorylation. J. Biol. Chem. 2001, 276, 275-280.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 275-280
-
-
Hagopian, J.C.1
Kirtley, M.P.2
Stevenson, L.M.3
Gergis, R.M.4
Russo, A.A.5
Pavletich, N.P.6
Parsons, S.M.7
Lew, J.8
-
53
-
-
0142031483
-
Two rate-limiting steps in the kinetic mechanism of the serine/ threonine specific protein kinase ERK2: A case of fast phosphorylation followed by fast product release
-
Waas, W. F.; Rainey, M. A.; Szafranska, A. E.; Dalby, K. N. Two rate-limiting steps in the kinetic mechanism of the serine/ threonine specific protein kinase ERK2: a case of fast phosphorylation followed by fast product release. Biochemistry 2003, 42, 12273-12286.
-
(2003)
Biochemistry
, vol.42
, pp. 12273-12286
-
-
Waas, W.F.1
Rainey, M.A.2
Szafranska, A.E.3
Dalby, K.N.4
-
54
-
-
0033517739
-
Catalytic mechanism of phosphorylase kinase probed by mutational studies
-
Skamnaki, V. T.; Owen, D. J.; Noble, M. E.; Lowe, E. D.; Lowe, G.; Oikonomakos, N. G.; Johnson, L. N. Catalytic mechanism of phosphorylase kinase probed by mutational studies. Biochemistry 1999, 38, 14718-14730.
-
(1999)
Biochemistry
, vol.38
, pp. 14718-14730
-
-
Skamnaki, V.T.1
Owen, D.J.2
Noble, M.E.3
Lowe, E.D.4
Lowe, G.5
Oikonomakos, N.G.6
Johnson, L.N.7
-
55
-
-
0035964287
-
Mechanistic effects of autophosphorylation on receptor tyrosine kinase catalysis: Enzymatic characterization of tie2 and phosphotie2
-
Murray, B. W.; Padrique, E. S.; Pinko, C.; McTigue, M. A. Mechanistic effects of autophosphorylation on receptor tyrosine kinase catalysis: enzymatic characterization of tie2 and phosphotie2. Biochemistry 2001, 40, 10243-10253.
-
(2001)
Biochemistry
, vol.40
, pp. 10243-10253
-
-
Murray, B.W.1
Padrique, E.S.2
Pinko, C.3
McTigue, M.A.4
-
56
-
-
0035958029
-
Structural characterization of protein kinase A as a function of nucleotide binding: Hydrogen-deuterium exchange studies using MALDI-TOF MS detection
-
Andersen, M. D.; Shaffer, J.; Jennings, P. A.; Adams, J. A. Structural Characterization of Protein Kinase A as a function of Nucleotide Binding: Hydrogen-Deuterium Exchange Studies using MALDI-TOF MS Detection. J. Biol. Chem. 2001, 276, 14204-14211.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14204-14211
-
-
Andersen, M.D.1
Shaffer, J.2
Jennings, P.A.3
Adams, J.A.4
-
57
-
-
0034720166
-
Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases
-
Kawabuchi, M.; Satomi, Y.; Takao, T.; Shimonishi, Y.; Nada, S.; Nagai, K.; Tarakhovsky, A.; Okada, M. Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases. Nature 2000, 404, 999-1003.
-
(2000)
Nature.
, vol.404
, pp. 999-1003
-
-
Kawabuchi, M.1
Satomi, Y.2
Takao, T.3
Shimonishi, Y.4
Nada, S.5
Nagai, K.6
Tarakhovsky, A.7
Okada, M.8
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