The role of the putative catalytic base in the phosphoryl transfer reaction in a protein kinase: First-principles calculations

Journal of the American Chemical Society

Volumn 125, Issue 33, 2003, Pages 9926-9927

  Valiev, Marat ^a   Kawai, R ^b   Adams, Joseph A ^a   Weare, John H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; PHOSPHORUS DERIVATIVE; PROTEIN KINASE; SERINE; THREONINE; TYROSINE;

ARTICLE; CALCULATION; CATALYSIS; ENZYME MECHANISM; MODEL; STRUCTURE ANALYSIS;

ASPARTIC ACID; BINDING SITES; CATALYSIS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; MODELS, CHEMICAL; MODELS, MOLECULAR; PHOSPHORYLATION; QUANTUM THEORY; THERMODYNAMICS;

EID: 0043023392     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja029618u     Document Type: Article

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