Activation loop phosphorylation and catalysis in protein kinases: Is there functional evidence for the autoinhibitor model?

Biochemistry

Volumn 42, Issue 3, 2003, Pages 601-607

  Adams, Joseph A ^a  

^a San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION LOOP;

ENZYMES; INSULIN; POLYPEPTIDES; X RAY CRYSTALLOGRAPHY;

CATALYSTS;

ADENOSINE TRIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN ACTIVATING KINASE; CYCLIN DEPENDENT KINASE 2; FIBROBLAST GROWTH FACTOR RECEPTOR; INSULIN RECEPTOR; KEMPTIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL KINASE; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; PROTEIN SERINE KINASE; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DISSOCIATION CONSTANT; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; VISCOSITY; X RAY CRYSTALLOGRAPHY;

CATALYSIS; ENZYME ACTIVATION; ENZYME INHIBITORS; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY;

EID: 0037469146     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi020617o     Document Type: Article

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