Structural characterization of protein kinase A as a function of nucleotide binding. Hydrogen-deuterium exchange studies using matrix-assisted laser desorption ionization-time of flight mass spectrometry detection

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 14204-14211

  Andersen, Mette D ^b   Shaffer, Jennifer ^a   Jennings, Patricia A ^b   Adams, Joseph A ^a  

^a San Diego   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DEUTERIUM; ENZYME KINETICS; HYDROGEN; LASER APPLICATIONS; MASS SPECTROMETRY; NUCLEIC ACIDS;

ACTIVE SITES;

ENZYMES;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DEUTERIUM; HYDROGEN; NUCLEOTIDE; PROTEIN KINASE; GLYCINE; ISOPROTEIN;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; ESCHERICHIA COLI; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVATION; KINETICS; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MOUSE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; TIME;

ESCHERICHIA COLI;

ADENOSINE DIPHOSPHATE; ANIMALS; BINDING SITES; CATALYSIS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DEUTERIUM; ENZYME ACTIVATION; ESCHERICHIA COLI; GLYCINE; HYDROGEN; KINETICS; MICE; MODELS, MOLECULAR; NUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TIME FACTORS;

EID: 0035958029     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011543200     Document Type: Article

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