Evidence for an internal entropy contribution to phosphoryl transfer: A study of domain closure, backbone flexibility, and the catalytic cycle of cAMP-dependent protein kinase

Journal of Molecular Biology

Volumn 315, Issue 3, 2002, Pages 459-469

  Li, Fei ^a   Gangal, Milind ^a   Juliano, Celina ^b   Gorfain, Elliot ^b   Taylor, Susan S ^b   Johnson, David A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cAMP dependent protein kinase; Conformational flexibility; Entropy; Fluorescent resonance energy transfer; Time resolved fluorescence anisotropy

Indexed keywords

5 MALEIMIDOFLUORESCEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYSTEINE; MALEIMIDE DERIVATIVE; MUTANT PROTEIN; RHODAMINE; TETRAMETHYLRHODAMINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONJUGATION; ENTROPY; ENZYME CONFORMATION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; ENZYME SUBUNIT; FLUORESCENCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOOTPRINTING; RADIATION SCATTERING; THERMOSTABILITY;

EID: 0036306530     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5256     Document Type: Article

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