Secreted antibody/granzyme B fusion protein stimulates selective killing of HER2-overexpressing tumor cells

Journal of Biological Chemistry

Volumn 279, Issue 20, 2004, Pages 21343-21348

  Zhao, Jing ^a   Zhang, Li Hong ^a   Jia, Lin Tao ^a   Zhang, Li ^a   Xu, Yan Ming ^a   Wang, Zhi ^a   Yu, Cui Juan ^a   Peng, Wei Dan ^a   Wen, Wei Hong ^a   Wang, Cheng Ji ^a   Chen, Si Yi ^b   Yang, An Gang ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b CENTER FOR CELL AND GENE THERAPY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BLOOD; ENZYMES; IMMUNOLOGY; ONCOLOGY; TUMORS;

INTRAMASCULAR INJECTIONS; LYMPH FLUIDS;

BIOCHEMISTRY;

EPIDERMAL GROWTH FACTOR RECEPTOR 2; GRANZYME B; HYBRID PROTEIN; PSEUDOMONAS EXOTOXIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL KILLING; CELL STIMULATION; CHIMERA; CONTROLLED STUDY; EXPRESSION VECTOR; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOGRB GENE; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SECRETION; TARGET CELL; TUMOR CELL; TUMOR GROWTH;

ANIMALS; ANTIBODIES; APOPTOSIS; BREAST NEOPLASMS; CELL DEATH; CELL LINE, TUMOR; FEMALE; GRANZYMES; HUMANS; MICE; MICE, NUDE; RECEPTOR, ERBB-2; RECOMBINANT FUSION PROTEINS; SERINE ENDOPEPTIDASES; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS;

ANIMALIA; CHEN; JIA; MUS MUSCULUS; PSEUDOMONAS; VECTORS;

EID: 2442675502     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312648200     Document Type: Article

References (45)

1. Hynes, N. E., and Stern, D. F. (1994) Biochim. Biophys. Acta 1198, 165-184
2. Press, M. F., Pike, M. C., Hung, G., Zhou, J. Y., Ma, Y., George, J., Dietz-Band, J., James, W., Slamon, D. J., Batsakis, J. G., and El-Naggar, A. K. (1994) Cancer Res. 54, 5675-5682
3. Kapitanovic, S., Radosevic, S., Kapitanovic, M., Andelinovic, S., Ferencic, Z., Tavassoli, M., Primorac, D., Sonicki, Z., Spaventi, S., Pavelic, K., and Spaventi, R. (1997) Gastroenterology 112, 1103-1113
4. Ranson, M., and Sliwkowski, M. X. (2002) Oncology (Basel) 63, Suppl. 1, 17-24
5. Plunkett, T. A., and Miles, D. W. (2002) Int. J. Clin. Pract. 56, 261-266
6. Head, J. F., Elliott, R. L., and Yang, D. C. (2002) Expert Opin. Ther. Targets 6, 375-385
7. Foy, T. M., Fanger, G. R., Hands, S., Gerard, C., Bruck, C., and Cheever, M. A. (2002) Semin. Oncol. 29, 3 Suppl. 11, 53-61
8. Leyland-Jones, S. (2002) Lancet Oncol. 3, 137-144
9. Tan-Chiu, E., and Piccart, M. (2002) Oncology (Basel) 63, Suppl. 1, 57-63
10. Keefe, D. L. (2002) Cancer 95, 1592-1600
11. Graus-Porta, D., Beerli, R. R., and Hynes, N. E. (1995) Mol. Cell. Biol. 15, 1182-1191
12. Wright, M., Grim, J., Deshane, J., Kim, M., Strong, T. V., Siegal, G. P., and Curiel, D. T. (1997) Gene Ther. 4, 317-322
13. Batra, J. K., Kasprzyk, P. G., Bird, R. E., Pastan, I., and King, C. R. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5867-5871
14. Rosenblum, M. G., Shawver, L. K., Marks, J. W., Brink, J., Cheung, L., and Langton-Webster, B. (1999) Clin. Cancer Res. 5, 865-874
15. Frankel, A. E., Kreitman, R. J., and Sausville, E. A. (2000) Clin. Cancer Res. 6, 326-334
16. Rosenblum, M. G., Horn, S. A., and Cheung, L. H. (2000) Int. J. Cancer 88, 267-273
17. Dela Cruz, J. S., Trinh, K. R., Morrison, S. L., and Penichet, M. L. (2000) J. Immunol. 165, 5112-5121
18. Chen, S. Y., Yang, A. G., Chen, J. D., Kute, T., King, C. R., Collier, J., Cong, Y., Yao, C., and Huang, X. F. (1997) Nature 385, 78-80
19. Yang, A. G., and Chen, S. Y. (1997) Nat. Biotechnol. 15, 46-51
20. Trapani, J. A. (2001) Genome Biol. 2, REVIEWS3014, 1-7
21. Edwards, K. M., Davis, J. E., Browne, K. A., Sutton, V. R., and Trapani, J. A. (1999) Immunol. Cell Biol. 77, 76-89
22. Pinkoski, M. J., Hobman, M., Heibein, J. A., Tomaselli, K., Li, F., Seth, P., Froelich, C. J., and Bleackley, R. C. (1998) Blood 92, 1044-1054
23. Kam, C. M., Hudig, D., and Powers, J. C. (2000) Biochim. Biophys. Acta 1477, 307-323
24. Andrade, F., Roy, S., Nicholson, D., Thornberry, N., Rosen, A., Casciola-Rosen, L. (1998) Immunity 8, 451-460
25. Pinkoski, M. J., Heibein, J. A., Barry, M., and Bleackley, R. C. (2000) Cell Death Differ. 7, 17-24
26. Alimonti, J. B., Shi, L., Baijal, P. K., Greenberg, A. H. (2001) J. Biol. Chem. 276, 6974-6982
27. Browne, K. A., Johnstone, R. W., Jans, D. A., and Trapani, J. A. (2000) J. Biol. Chem. 275, 39262-39266
28. Thomas, D. A., Du, C., Xu, M., Wang, X., and Ley, T. J. (2000) Immunity 12, 621-632
29. Jia, L. T., Zhang, L. H., Yu, C. J., Zhao, J., Xu, Y. M., Gui, J. H., Jin, M., Ji, Z. L., Wen, W. H., Wang, C. J., Chen, S. Y., and Yang, A. G. (2003) Cancer Res. 63, 3257-3262
30. Pelegrin, M., Marin, M., Noel, D., and Piechaczyk, M. (1998) Hum. Gene Ther. 9, 2165-2175
31. Neve, R. M., Nielsen, U. B., Kirpotin, D. B., Poul, M. A., Marks, J. D., and Benz, C. C. (2001) Biochem. Biophys. Res. Commun. 280, 274-279
32. Ogata, M., Fryling, C. M., Pastan, I., and FitzGeraldg, D. J. (1992) J. Biol. Chem. 267, 25396-25401
33. Prior, T. I., FitzGerald, D. J., and Pastan, I. (1992) Biochemistry 31, 3555-3559
34. Taupiac, M. P., Bebien, M., Alami, M., and Beaumelle, B. (1999) Mol. Microbiol. 31, 1385-1393
35. Kreitman, R. J. (2001) Curr. Opin. Investig. Drugs 2, 1282-1293
36. Horton, R. M., Hunt, H. D., Ho, S. N., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 77, 61-68
37. Osborne, C. K., Hobbs, K., and Clark, G. M. (1985) Cancer Res. 45, 584-590
38. Coopman, P. J., Do, M. T., Barth, M., Bowden, E. T., Hayes, A. J., Basyuk, E., Blancato, J. K., Vezza, P. R., McLeskey, S. W., Mangeat, P. H., and Mueller, S. C. (2000) Nature 406, 742-747
39. Motyka, B., Korbutt, G., Pinkoski, M. J., Heibein, J. A., Caputo, A., Hobman, M., Barry, M., Shostak, I., Sawchuk, T., Holmes, C. F., Gauldie, J., and Bleackley, R. C. (2000) Cell 103, 491-500
40. Froelich, C. J., Orth, K., Turbov, J., Seth, P., Gottlieb, R., Babior, B., Shah, G. M., Bleackley, R. C., Dixit, V. M., and Hanna, W. (1996) J. Biol. Chem. 271, 29073-29079
41. Iwasaka, T., Zheng, P. S., Ouchida, M., Yamasaki, H., Yokoyama, M., and Sugimori, H. (1996) Acta Obstet. Gynecol. Scand. 75, 797-803
42. Elliott, M. J., Murphy, K. M., Stribinskiene, L., Ranganathan, V., Sturges, E., Farnsworth, M. L., and Lock, R. B. (1999) Cancer Chemother. Pharmacol. 44, 1-11
43. Fokkema, E., De Vries, E. G., Groen, H. J., Meijer, C., and Timens, W. (2003) Virchows Arch. 442, 349-355
44. Kolenko, V. M., Uzzo, R. G., Bukowski, R., and Finke, J. H. (2000) Apoptosis 5, 17-20
45. Press, M. F., Cordon-Cardo, C., and Slamon, D. J. (1990) Oncogene 5, 953-962