Comparison of Taurine- and Glycine-induced Conformational Changes in the M2-M3 Domain of the Glycine Receptor

Journal of Biological Chemistry

Volumn 279, Issue 19, 2004, Pages 19559-19565

  Han, Nian Lin R ^a,c   Clements, John D ^b   Lynch, Joseph W ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b Biology and Environment   (Australia)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; AMMONIUM COMPOUNDS; CONFORMATIONS; PROTEINS; REACTION KINETICS;

CONFORMATIONAL CHANGES; GLUTAMATE RECEPTORS; LIGANDS;

BIOCHEMISTRY;

ARGININE; CHLORIDE CHANNEL; CYSTEINE; GLYCINE; GLYCINE RECEPTOR; ION CHANNEL; LYSINE; METHANETHIOSULFONATE ETHYLTRIMETHYLAMMONIUM; SULFONIC ACID DERIVATIVE; TAURINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; ION CURRENT; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; REACTION TIME; RECEPTOR UPREGULATION;

ARGININE; BINDING SITES; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; GLYCINE; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; LYSINE; MESYLATES; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, GLYCINE; SULFHYDRYL REAGENTS; TAURINE; TIME FACTORS;

EID: 2442423159     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400548200     Document Type: Article

References (36)

1. Legendre, P. (2001) Cell. Mol. Life Sci. 58, 760-793
2. Laube, B., Maksay, G., Schemm, R., and Betz, H. (2002) Trends Pharmacol. Sci. 23, 519-527
3. Karlin, A. (2002) Nat. Rev. Neurosci. 3, 102-114
4. Miyazawa, A., Fujiyoshi, Y., and Unwin, N. (2003) Nature 424, 949-955
5. Wilson, G. G., and Karlin, A. (1998) Neuron 20, 1269-1281
6. Brejc, K., van Dijk, W. J., Klaassen, R. V., Schuurmans, M., van Der Oost, J., Smit, A. B., and Sixma, T. K. (2001) Nature 411, 269-276
7. Grosman, C., Zhou, M., and Auerbach, A. (2000) Nature 403, 773-776
8. Colquhoun, D. (1998) Br. J. Pharmacol. 125, 924-947
9. Armstrong, N., and Gouaux, E. (2000) Neuron 28, 165-181
10. Armstrong, N., Mayer, M., and Gouaux, E. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 5736-5741
11. Jin, R., Banke, T. G., Mayer, M. L., Traynelis, S. F., and Gouaux, E. (2003) Nat. Neurosci. 6, 803-810
12. Lewis, T. M., Schofield, P. R., and McClellan, A. M. (2003) J. Physiol. (Lond.) 549, 361-374
13. Karlin, A., and Akabas, M. H. (1998) Methods Enzymol. 293, 123-145
14. Lynch, J. W., Han, N. L., Haddrill, J., Pierce, K. D., and Schofield, P. R. (2001) J. Neurosci. 21, 2589-2599
15. Lynch, J. W., Rajendra, S., Pierce, K. D., Handford, C. A., Barry, P. H., and Schofield, P. R. (1997) EMBO J. 16, 110-120
16. Lewis, T. M., Sivilotti, L. G., Colquhoun, D., Gardiner, R. M., Schoepfer, R., and Rees, M. (1998) J. Physiol. (Lond.) 507, 25-40
17. Absalom, N. L., Lewis, T. M., Kaplan, W., Pierce, K. D., and Schofield, P. R. (2003) J. Biol. Chem. 278, 50151-50157
18. Schofield, C. M., Jenkins, A., and Harrison, N. L. (2003) J. Biol. Chem. 278, 34079-34083
19. Fisher, J. L., and Macdonald, R. L. (1998) J. Neurosci. 18, 2944-2953
20. Boileau, A. J., and Czajkowski, C. (1999) J. Neurosci. 19, 10213-10220
21. O'Shea, S. M., and Harrison, N. L. (2000) J. Biol. Chem. 275, 22764-22768
22. Bera, A. K., Chatav, M., and Akabas, M. H. (2002) J. Biol. Chem. 277, 43002-43010
23. Kash, T. L., Jenkins, A., Kelley, J. C., Trudell, J. R., and Harrison, N. L. (2003) Nature 421, 272-275
24. Kash, T. L., Dizon, M. J., Trudell, J. R., and Harrison, N. L. (2003) J. Biol. Chem. 279, 4887-4893
25. Rovira, J. C., Ballesta, J. J., Vicente-Agullo, F., Campos-Caro, A., Criado, M., Sala, F., and Sala, S. (1998) FEBS Lett. 433, 89-92
26. Rovira, J. C., Vicente-Agullo, F., Campos-Caro, A., Criado, M., Sala, F., Sala, S., and Ballesta, J. J. (1999) Pfluegers Arch. 439, 86-92
27. Grosman, C., Salamone, F. N., Sine, S. M., and Auerbach, A. (2000) J. Gen. Physiol. 116, 327-340
28. Corringer, P. J., Le Novere, N., and Changeux, J. P. (2000) Annu. Rev. Pharmacol. Toxicol. 40, 431-458
29. Schmieden, V., Kuhse, J., and Betz, H. (1992) EMBO J. 11, 2025-2032
30. Schmieden, V., Kuhse, J., and Betz, H. (1993) Science 262, 256-258
31. Schmieden, V., and Betz, H. (1995) Mol. Pharmacol. 48, 919-927
32. Rajendra, S., Vandenberg, R. J., Pierce, K. D., Cunningham, A. M., French, P. W., Barry, P. H., and Schofield, P. R. (1995) EMBO J. 14, 2987-2998
33. Kelley, S. P., Dunlop, J. I., Kirkness, E. F., Lambert, J. J., and Peters, J. A. (2003) Nature 424, 321-324
34. Changeux, J. P., and Edelstein, S. J. (1998) Neuron 21, 959-980
35. Koshland, D. E., Jr., Nemethy, G., and Filmer, D. (1966) Biochemistry 5, 365-385
36. Shan, Q., Nevin, S. T., Haddrill, J. L., and Lynch, J. W. (2003) J. Neurochem. 86, 498-507