Power and sample size calculations for genetic case/control studies using gene-centric SNP maps: Application to human chromosomes 6, 21, and 22 in three populations

Human Heredity

Volumn 60, Issue 1, 2005, Pages 43-60

  De La Vega, Francisco M ^a   Gordon, Derek ^b   Su, Xiaoping ^a,c   Scafe, Charles ^a   Isaac, Hadar ^a   Gilbert, Dennis A ^a   Spier, Eugene G ^a  

^a APPLIED BIOSYSTEMS   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Association studies; Case control; Linkage disequilibrium; Sample size; SNP; Statistical power; Study design

Indexed keywords

AFRICAN AMERICAN; ALLELE; ANALYTIC METHOD; ARTICLE; CAUCASIAN; CHINESE; CHROMOSOME 21; CHROMOSOME 22; CHROMOSOME 6; CHROMOSOME ANALYSIS; DATA ANALYSIS; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENETIC DISORDER; GENETIC MARKER; GENETIC MODEL; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; MATHEMATICAL ANALYSIS; POPULATION GENETICS; PSORIASIS; REGRESSION ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS;

AFRICAN AMERICANS; CASE-CONTROL STUDIES; CHINA; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, HUMAN, PAIR 22; CHROMOSOMES, HUMAN, PAIR 6; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PSORIASIS; SAMPLE SIZE; VARIATION (GENETICS);

EID: 24344450191     PISSN: 00015652     EISSN: None     Source Type: Journal    
DOI: 10.1159/000087918     Document Type: Article

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