The power of genome-wide association studies of complex disease genes: Statistical limitations of indirect approaches using SNP markers

Journal of Human Genetics

Volumn 46, Issue 8, 2001, Pages 478-482

  Ohashi, J ^a   Tokunaga, K ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Case control study; Genome wide association studies; Market allele frequency; Power linkage disequilibrium; Sample size; SNPs

Indexed keywords

ARTICLE; CASE CONTROL STUDY; DISEASE ASSOCIATION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENOME; HUMAN; MARKER GENE; MATHEMATICAL COMPUTING; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS;

GENE FREQUENCY; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; HUMANS; LINKAGE (GENETICS); LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MODELS, STATISTICAL; POLYMORPHISM, SINGLE NUCLEOTIDE; RESEARCH DESIGN; SAMPLE SIZE; VARIATION (GENETICS);

EID: 0034890791     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100380170048     Document Type: Article

References (11)

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