메뉴 건너뛰기




Volumn 5, Issue 4, 2005, Pages 226-240

Hanging in the balance: KIR and their role in disease

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2D; RECEPTOR; UNCLASSIFIED DRUG;

EID: 24144434732     PISSN: 15340384     EISSN: None     Source Type: Journal    
DOI: 10.1124/mi.5.4.6     Document Type: Review
Times cited : (89)

References (130)
  • 1
    • 0022616253 scopus 로고
    • Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy
    • Karre, K., Ljunggren, H.G., Piontek, G. and Kiessling, R. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 319, 675-678 (1986). This paper shows that NK cells can reject tumors based on the absence of MHC class I expression and formed the basis for the missing-self hypothesis. It forms the basis for distinguishing NK cell reactivities from T cell reactivity.
    • (1986) Nature , vol.319 , pp. 675-678
    • Karre, K.1    Ljunggren, H.G.2    Piontek, G.3    Kiessling, R.4
  • 2
    • 0024792513 scopus 로고
    • Biology of natural killer cells
    • Trinchieri, G. Biology of natural killer cells. Adv. Immunol. 47, 187-376 (1989).
    • (1989) Adv. Immunol. , vol.47 , pp. 187-376
    • Trinchieri, G.1
  • 4
    • 0037017387 scopus 로고    scopus 로고
    • Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells
    • Ferlazzo, G., Tsang, M.L., Moretta, L., Melioli, G., Steinman, R.M., and Munz, C. Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells. J. Exp. Med. 195, 343-351 (2002).
    • (2002) J. Exp. Med. , vol.195 , pp. 343-351
    • Ferlazzo, G.1    Tsang, M.L.2    Moretta, L.3    Melioli, G.4    Steinman, R.M.5    Munz, C.6
  • 6
    • 0037017379 scopus 로고    scopus 로고
    • Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells
    • Piccioli, D., Sbrana, S., Melandri, E., and Valiante, N.M. Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells. J. Exp. Med. 195, 335-341 (2002).
    • (2002) J. Exp. Med. , vol.195 , pp. 335-341
    • Piccioli, D.1    Sbrana, S.2    Melandri, E.3    Valiante, N.M.4
  • 7
  • 8
    • 0031974018 scopus 로고    scopus 로고
    • Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1alpha (MIP-1alpha)-dependent pathways
    • Salazar-Mather, T.P., Orange, J.S., and Biron, C.A. Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1alpha (MIP-1alpha)-dependent pathways. J. Exp. Med. 187, 1-14 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 1-14
    • Salazar-Mather, T.P.1    Orange, J.S.2    Biron, C.A.3
  • 9
    • 0024315206 scopus 로고
    • Severe herpesvirus infections in an adolescent without natural killer cells
    • Biron, C.A., Byron, K.S., and Sullivan, J.L. Severe herpesvirus infections in an adolescent without natural killer cells. N. Engl. J. Med. 320, 1731-1735 (1989).
    • (1989) N. Engl. J. Med. , vol.320 , pp. 1731-1735
    • Biron, C.A.1    Byron, K.S.2    Sullivan, J.L.3
  • 10
    • 0036931320 scopus 로고    scopus 로고
    • Human natural killer cell deficiencies and susceptibility to infection
    • Orange, J.S. Human natural killer cell deficiencies and susceptibility to infection. Microbes Infect. 4, 1545-1558 (2002).
    • (2002) Microbes Infect. , vol.4 , pp. 1545-1558
    • Orange, J.S.1
  • 11
    • 0032503029 scopus 로고    scopus 로고
    • Viral strategies of immune evasion
    • Ploegh, H.L. Viral strategies of immune evasion. Science 280, 248-253 (1998).
    • (1998) Science , vol.280 , pp. 248-253
    • Ploegh, H.L.1
  • 13
    • 0020591841 scopus 로고
    • Natural killer cell depletion enhances virus synthesis and virus-induced hepatitis in vivo
    • Bukowski, J.F., Woda, B.A., Habu, S., Okumura, K., and Welsh, R.M. Natural killer cell depletion enhances virus synthesis and virus-induced hepatitis in vivo. J. Immunol. 131, 1531-1538 (1983).
    • (1983) J. Immunol. , vol.131 , pp. 1531-1538
    • Bukowski, J.F.1    Woda, B.A.2    Habu, S.3    Okumura, K.4    Welsh, R.M.5
  • 14
    • 0031926095 scopus 로고    scopus 로고
    • Role of interleukin-12 in primary influenza virus infection
    • Monteiro, J.M., Harvey, C., and Trinchieri, G. Role of interleukin-12 in primary influenza virus infection. J. Virol. 72, 4825-4831 (1998).
    • (1998) J. Virol. , vol.72 , pp. 4825-4831
    • Monteiro, J.M.1    Harvey, C.2    Trinchieri, G.3
  • 15
    • 0025300414 scopus 로고
    • In search of the "missing self": MHC molecules and NK cell recognition
    • Ljunggren, H.G. and Karre, K. In search of the "missing self": MHC molecules and NK cell recognition. Immunol. Today 11, 237-44 (1990). This was the original description of the "missing-self" model, which has formed the basis for our current understanding of NK cell inhibitory receptors.
    • (1990) Immunol. Today , vol.11 , pp. 237-244
    • Ljunggren, H.G.1    Karre, K.2
  • 16
    • 0342948593 scopus 로고    scopus 로고
    • A role for MHC class I down-regulation in NK cell lysis of herpes virus-infected cells
    • Huard, B. and Fruh, K. A role for MHC class I down-regulation in NK cell lysis of herpes virus-infected cells. Eur. J. Immunol. 30, 509-515 (2000).
    • (2000) Eur. J. Immunol. , vol.30 , pp. 509-515
    • Huard, B.1    Fruh, K.2
  • 17
    • 0031879322 scopus 로고    scopus 로고
    • The susceptibility to natural killer cell-mediated lysis of HLA class I-positive melanomas reflects the expression of insufficient amounts of different HLA class I alleles
    • Pende, D., Accame, L., Pareti, L., Mazzocchi, A., Moretta, A., Parmiani, G., Moretta, L. The susceptibility to natural killer cell-mediated lysis of HLA class I-positive melanomas reflects the expression of insufficient amounts of different HLA class I alleles. Eur. J. Immunol. 28, 2384-2394 (1998).
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2384-2394
    • Pende, D.1    Accame, L.2    Pareti, L.3    Mazzocchi, A.4    Moretta, A.5    Parmiani, G.6    Moretta, L.7
  • 18
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    • Bauer, S., Groh, V., Wu, J., Steinle, A., Phillips, J.H., Lanier, L.L., and Spies, T. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285, 727-729 (1999).
    • (1999) Science , vol.285 , pp. 727-729
    • Bauer, S.1    Groh, V.2    Wu, J.3    Steinle, A.4    Phillips, J.H.5    Lanier, L.L.6    Spies, T.7
  • 19
    • 0032945045 scopus 로고    scopus 로고
    • NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells
    • Sivori, S., Pende. D., Bottino, C., Marcenaro, E., Pessino, A., Biassoni, R., Moretta, L., Moretta, A. NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells. Eur. J. Immunol. 29, 1656-1666 (1999).
    • (1999) Eur. J. Immunol. , vol.29 , pp. 1656-1666
    • Sivori, S.1    Pende, D.2    Bottino, C.3    Marcenaro, E.4    Pessino, A.5    Biassoni, R.6    Moretta, L.7    Moretta, A.8
  • 20
    • 0035695983 scopus 로고    scopus 로고
    • Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3
    • Radaev, S., Rostro, B., Brooks, A.G., Colonna, M., and Sun, P.D. Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3. Immunity 15, 1039-1049 (2001).
    • (2001) Immunity , vol.15 , pp. 1039-1049
    • Radaev, S.1    Rostro, B.2    Brooks, A.G.3    Colonna, M.4    Sun, P.D.5
  • 21
    • 0033672658 scopus 로고    scopus 로고
    • Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice
    • Cerwenka, A., Bakker, A.B., McClanahan, T., Wagner, J., Wu, J., Phillips, J.H., and Lanier, L.L. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 12, 721-727 (2000).
    • (2000) Immunity , vol.12 , pp. 721-727
    • Cerwenka, A.1    Bakker, A.B.2    McClanahan, T.3    Wagner, J.4    Wu, J.5    Phillips, J.H.6    Lanier, L.L.7
  • 22
    • 0032526860 scopus 로고    scopus 로고
    • NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complexrestricted tumor cell lysis
    • Vitale, M., Bottino, C., Sivori, S., Sanseverino, L., Castriconi, R., Marcenaro, E., Augugliaro, R., Moretta, L., and Moretta, A. NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complexrestricted tumor cell lysis. J. Exp. Med. 187, 2065-2072 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 2065-2072
    • Vitale, M.1    Bottino, C.2    Sivori, S.3    Sanseverino, L.4    Castriconi, R.5    Marcenaro, E.6    Augugliaro, R.7    Moretta, L.8    Moretta, A.9
  • 23
    • 0027284452 scopus 로고
    • P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities
    • Moretta, A., Vitale, M., Bottino, C., Orengo, A.M., Morelli, L., Augugliaro, R., Barbaresi, M., Ciccone, E., and Moretta, L. P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities. J. Exp. Med. 178, 597-604 (1993).
    • (1993) J. Exp. Med. , vol.178 , pp. 597-604
    • Moretta, A.1    Vitale, M.2    Bottino, C.3    Orengo, A.M.4    Morelli, L.5    Augugliaro, R.6    Barbaresi, M.7    Ciccone, E.8    Moretta, L.9
  • 24
    • 0025267879 scopus 로고
    • A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function
    • Moretta, A., Tambussi, G., Bottino, C., Tripodi, G., Merli, A., Ciccone, E., Pantaleo, G., and Moretta, L. A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. J. Exp. Med. 171, 695-714 (1990).
    • (1990) J. Exp. Med. , vol.171 , pp. 695-714
    • Moretta, A.1    Tambussi, G.2    Bottino, C.3    Tripodi, G.4    Merli, A.5    Ciccone, E.6    Pantaleo, G.7    Moretta, L.8
  • 25
    • 0026628008 scopus 로고
    • MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells
    • Karlhofer, F.M., Ribaudo, R.K., and Yokoyama, W.M. MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells. Nature 358, 66-70 (1992).
    • (1992) Nature , vol.358 , pp. 66-70
    • Karlhofer, F.M.1    Ribaudo, R.K.2    Yokoyama, W.M.3
  • 26
    • 3142714284 scopus 로고    scopus 로고
    • Identification of probabilistic transcriptional switches in the Ly49 gene cluster: A eukaryotic mechanism for selective gene activation
    • Saleh, A., Davies, G.E., Pascal, V., Wright, P.W., Hodge, D.L., Cho, E.H., Lockett, S.J., Abshari, M., and Anderson, S.K. Identification of probabilistic transcriptional switches in the Ly49 gene cluster: A eukaryotic mechanism for selective gene activation. Immunity 21, 55-66 (2004). An extremely interesting study of how NK cells might express their receptors clonally, without germline rearrangement based on the relative probabilities of transcription factor binding. They show that transcription occurring in the reverse direction of the Ly49 promoter inhibits transcription in the forward direction.
    • (2004) Immunity , vol.21 , pp. 55-66
    • Saleh, A.1    Davies, G.E.2    Pascal, V.3    Wright, P.W.4    Hodge, D.L.5    Cho, E.H.6    Lockett, S.J.7    Abshari, M.8    Anderson, S.K.9
  • 27
    • 8244230425 scopus 로고    scopus 로고
    • Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations
    • Mingari, M.C., Schiavetti, F., Ponte, M. et al. Human CD8+ T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations. Proc. Natl. Acad. Sci. U.S.A. 93, 12433-12438 (1996).
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 12433-12438
    • Mingari, M.C.1    Schiavetti, F.2    Ponte, M.3
  • 28
    • 0030200870 scopus 로고    scopus 로고
    • Chromosomal localization of the human natural killer cell class I receptor family genes to 19q13.4 by fluorescence in situ hybridization
    • Suto, Y., Maenaka, K., Yabe, T., Hirai, M., Tokunaga, K., Tadok, K., and Juji, T. Chromosomal localization of the human natural killer cell class I receptor family genes to 19q13.4 by fluorescence in situ hybridization. Genomics 35, 270-272 (1996).
    • (1996) Genomics , vol.35 , pp. 270-272
    • Suto, Y.1    Maenaka, K.2    Yabe, T.3    Hirai, M.4    Tokunaga, K.5    Tadok, K.6    Juji, T.7
  • 29
    • 0032510146 scopus 로고    scopus 로고
    • Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
    • Lanier, L.L., Corliss, B.C., Wu, J., Leong, C., and Phillips, J.H. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature 391, 703-707 (1998).
    • (1998) Nature , vol.391 , pp. 703-707
    • Lanier, L.L.1    Corliss, B.C.2    Wu, J.3    Leong, C.4    Phillips, J.H.5
  • 31
    • 0030036615 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C
    • Campbell, K.S., Dessing, M., Lopez-Botet, M., Cella, M. and Colonna, M. Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C. J. Exp. Med. 184, 93-100 (1996).
    • (1996) J. Exp. Med. , vol.184 , pp. 93-100
    • Campbell, K.S.1    Dessing, M.2    Lopez-Botet, M.3    Cella, M.4    Colonna, M.5
  • 32
    • 0027132097 scopus 로고
    • HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells
    • Colonna, M., Borsellino, G., Falco, M., Ferrara, G.B., and Strominger, J.L. HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells. Proc. Natl. Acad. Sci. U.S.A. 90, 12000-12004 (1993). This paper describes HLA-C as a ligand for NK cells and demonstrates that there are sub-populations of NK cells that respond differently to different HLA-C alleles.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 12000-12004
    • Colonna, M.1    Borsellino, G.2    Falco, M.3    Ferrara, G.B.4    Strominger, J.L.5
  • 33
    • 0029551048 scopus 로고
    • Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer
    • Wagtmann, N., Rajagopalan, S., Winter, C.C., Peruzzi, M., and Long, E.O. Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. Immunity 3, 801-809 (1995).
    • (1995) Immunity , vol.3 , pp. 801-809
    • Wagtmann, N.1    Rajagopalan, S.2    Winter, C.C.3    Peruzzi, M.4    Long, E.O.5
  • 34
    • 0027959069 scopus 로고
    • NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80
    • Cella, M., Longo, A., Ferrara, G.B., Strominger, J.L., and Colonna, M. NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80. J. Exp. Med. 180, 1235-1242 (1994).
    • (1994) J. Exp. Med. , vol.180 , pp. 1235-1242
    • Cella, M.1    Longo, A.2    Ferrara, G.B.3    Strominger, J.L.4    Colonna, M.5
  • 35
    • 0028897989 scopus 로고
    • The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor
    • Gumperz, J.E., Litwin, V., Phillips, J.H., Lanier, L.L., and Parham, P. The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. J. Exp. Med. 181, 1133-1144 (1995).
    • (1995) J. Exp. Med. , vol.181 , pp. 1133-1144
    • Gumperz, J.E.1    Litwin, V.2    Phillips, J.H.3    Lanier, L.L.4    Parham, P.5
  • 39
    • 15444371656 scopus 로고    scopus 로고
    • Cutting edge: KIR2DL4 transduces signals into human NK cells through association with the Fc receptor gamma protein
    • Kikuchi-Maki, A., Catina, T.L., and Campbell, K.S. Cutting edge: KIR2DL4 transduces signals into human NK cells through association with the Fc receptor gamma protein. J. Immunol. 174, 3859-3863 (2005).
    • (2005) J. Immunol. , vol.174 , pp. 3859-3863
    • Kikuchi-Maki, A.1    Catina, T.L.2    Campbell, K.S.3
  • 40
    • 0141886193 scopus 로고    scopus 로고
    • KIR2DL4 is an IL-2-regulated NK cell receptor that exhibits limited expression in humans but triggers strong IFN-gamma production
    • Kikuchi-Maki, A., Yusa, S., Catina, T.L., and Campbell, K.S. KIR2DL4 is an IL-2-regulated NK cell receptor that exhibits limited expression in humans but triggers strong IFN-gamma production. J. Immunol. 171, 3415-3425 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 3415-3425
    • Kikuchi-Maki, A.1    Yusa, S.2    Catina, T.L.3    Campbell, K.S.4
  • 41
    • 0033526056 scopus 로고    scopus 로고
    • A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells
    • Rajagopalan, S. and Long, E.O. A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells. J. Exp. Med. 189, 1093-1100 (1999).
    • (1999) J. Exp. Med. , vol.189 , pp. 1093-1100
    • Rajagopalan, S.1    Long, E.O.2
  • 42
    • 84861236595 scopus 로고    scopus 로고
    • EBMT. http://www.ebi.ac.uk/ipd/
  • 44
    • 0036839601 scopus 로고    scopus 로고
    • Killer Ig-like receptor haplotype analysis by gene content: Evidence for genomic diversity with a minimum of six basic framework haplotypes, each with multiple subsets
    • Hsu, K.C., Liu, X.R., Selvakumar, A., Mickelson, E., O'Reilly, R.J., and Dupont, B. Killer Ig-like receptor haplotype analysis by gene content: evidence for genomic diversity with a minimum of six basic framework haplotypes, each with multiple subsets. J. Immunol. 169, 5118-5129 (2002).
    • (2002) J. Immunol. , vol.169 , pp. 5118-5129
    • Hsu, K.C.1    Liu, X.R.2    Selvakumar, A.3    Mickelson, E.4    O'Reilly, R.J.5    Dupont, B.6
  • 46
    • 18244393431 scopus 로고    scopus 로고
    • Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues
    • Abi-Rached, L. and Parham, P. Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues. J. Exp. Med. 201, 1319-1332 (2005).
    • (2005) J. Exp. Med. , vol.201 , pp. 1319-1332
    • Abi-Rached, L.1    Parham, P.2
  • 47
    • 3843075120 scopus 로고    scopus 로고
    • HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection
    • Khakoo, S.I., Thio, C.L., and Martin, M.P. HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection. Science 305, 872-874 (2004). A paper proposing a model of anti-viral NK cell reactivity based on inhibitory, rather than activating, receptor: ligand combinations.
    • (2004) Science , vol.305 , pp. 872-874
    • Khakoo, S.I.1    Thio, C.L.2    Martin, M.P.3
  • 48
    • 0025754310 scopus 로고
    • DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells
    • Houchins, J.P., Yabe, T., McSherry, C., and Bach, F.H. DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. J. Exp. Med. 173, 1017-1020 (1991).
    • (1991) J. Exp. Med. , vol.173 , pp. 1017-1020
    • Houchins, J.P.1    Yabe, T.2    McSherry, C.3    Bach, F.H.4
  • 51
    • 0032473478 scopus 로고    scopus 로고
    • Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis
    • Borrego, F., Ulbrecht, M., Weiss, E.H., Coligan, J.E., and Brooks, A.G. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis. J. Exp. Med. 187, 813-818 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 813-818
    • Borrego, F.1    Ulbrecht, M.2    Weiss, E.H.3    Coligan, J.E.4    Brooks, A.G.5
  • 52
    • 0032546001 scopus 로고    scopus 로고
    • HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
    • Braud, V.M., Allan, D.S., O'Callaghan, C.A. et al. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 391, 795-799 (1998).
    • (1998) Nature , vol.391 , pp. 795-799
    • Braud, V.M.1    Allan, D.S.2    O'Callaghan, C.A.3
  • 54
    • 0035099068 scopus 로고    scopus 로고
    • ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
    • Cosman, D., Mullberg, J., Sutherland, C.L., Chin, W., Armitage, R., Fanslow, W., Kubin, M., and Chalupny, N.J. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 14, 123-133 (2001).
    • (2001) Immunity , vol.14 , pp. 123-133
    • Cosman, D.1    Mullberg, J.2    Sutherland, C.L.3    Chin, W.4    Armitage, R.5    Fanslow, W.6    Kubin, M.7    Chalupny, N.J.8
  • 55
    • 0032538916 scopus 로고    scopus 로고
    • Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b)
    • Vance, R.E., Kraft, J.R., Altman, J.D., Jensen, P.E., and Raulet, D.H. Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b). J. Exp. Med. 188, 1841-1848 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 1841-1848
    • Vance, R.E.1    Kraft, J.R.2    Altman, J.D.3    Jensen, P.E.4    Raulet, D.H.5
  • 57
    • 0038082247 scopus 로고    scopus 로고
    • The natural killer cell-mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors
    • Della Chiesa, M., Vitale, M., Carlomagno, S., Ferlazzo, G., Moretta, L., and Moretta, A. The natural killer cell-mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors. Eur. J. Immunol. 33, 1657-1666 (2003).
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1657-1666
    • Della Chiesa, M.1    Vitale, M.2    Carlomagno, S.3    Ferlazzo, G.4    Moretta, L.5    Moretta, A.6
  • 58
    • 3242706150 scopus 로고    scopus 로고
    • The small subset of CD56brightCD16- natural killer cells is selectively responsible for both cell proliferation and interferon-gamma production upon interaction with dendritic cells
    • Vitale, M., Della Chiesa, M., Carlomagno, S., Romagnani, C., Thiel, A., Moretta, L., and Moretta, A. The small subset of CD56brightCD16- natural killer cells is selectively responsible for both cell proliferation and interferon-gamma production upon interaction with dendritic cells. Eur. J. Immunol. 34, 1715-1722 (2004).
    • (2004) Eur. J. Immunol. , vol.34 , pp. 1715-1722
    • Vitale, M.1    Della Chiesa, M.2    Carlomagno, S.3    Romagnani, C.4    Thiel, A.5    Moretta, L.6    Moretta, A.7
  • 59
    • 0033667771 scopus 로고    scopus 로고
    • Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans
    • Khakoo, S.I., Rajalingam, R., Shum, B.P. et al. Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans. Immunity 12, 687-698 (2000).
    • (2000) Immunity , vol.12 , pp. 687-698
    • Khakoo, S.I.1    Rajalingam, R.2    Shum, B.P.3
  • 60
    • 0035942184 scopus 로고    scopus 로고
    • Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity
    • Flores-Villanueva, P.O., Yunis, E.J., Delgado, J.C. et al. Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity. Proc. Natl. Acad. Sci. U.S.A. 98, 5140-5145 (2001).
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 5140-5145
    • Flores-Villanueva, P.O.1    Yunis, E.J.2    Delgado, J.C.3
  • 61
    • 0036699528 scopus 로고    scopus 로고
    • Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS
    • Martin, M.P., Gao, X., Lee, J.H. et al. Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat. Genet. 31, 429-434 (2002).
    • (2002) Nat. Genet. , vol.31 , pp. 429-434
    • Martin, M.P.1    Gao, X.2    Lee, J.H.3
  • 63
    • 0032929792 scopus 로고    scopus 로고
    • Differential regulation of killer cell Ig-like receptors and CD94 lectin-like dimers on NK and T lymphocytes from HIV-1-infected individuals
    • Andre, P., Brunet, C., Guia, S., Gallais, H., Sampol, J., Vivier, E., and Dignat-George, F. Differential regulation of killer cell Ig-like receptors and CD94 lectin-like dimers on NK and T lymphocytes from HIV-1-infected individuals. Eur. J. Immunol. 29, 1076-1085 (1999).
    • (1999) Eur. J. Immunol. , vol.29 , pp. 1076-1085
    • Andre, P.1    Brunet, C.2    Guia, S.3    Gallais, H.4    Sampol, J.5    Vivier, E.6    Dignat-George, F.7
  • 64
    • 0035205323 scopus 로고    scopus 로고
    • Distribution of the natural killer-related receptor for HLA-C during highly active antiretroviral therapy for human immunodeficiency virus infection
    • Sirianni, M.C., Ensoli, F., Alario, C., Fiorelli, V., Sacco, G., Topino, S., Iebba, F., Mezzaroma, I., and Aiuti, F. Distribution of the natural killer-related receptor for HLA-C during highly active antiretroviral therapy for human immunodeficiency virus infection. Hum. Immunol. 62, 1328-1334 (2001).
    • (2001) Hum. Immunol. , vol.62 , pp. 1328-1334
    • Sirianni, M.C.1    Ensoli, F.2    Alario, C.3    Fiorelli, V.4    Sacco, G.5    Topino, S.6    Iebba, F.7    Mezzaroma, I.8    Aiuti, F.9
  • 65
    • 0030922880 scopus 로고    scopus 로고
    • Expression of HLA class I-specific inhibitory natural killer cell receptors in HIV-specific cytolytic T lymphocytes: Impairment of specific cytolytic functions
    • De Maria, A., Ferraris, A., Guastella, M. et al. Expression of HLA class I-specific inhibitory natural killer cell receptors in HIV-specific cytolytic T lymphocytes: Impairment of specific cytolytic functions. Proc. Natl. Acad. Sci. U.S.A. 94, 10285-10288 (1997).
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 10285-10288
    • De Maria, A.1    Ferraris, A.2    Guastella, M.3
  • 66
    • 0033151621 scopus 로고    scopus 로고
    • The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells
    • Cohen, G.B., Gandhi, R.T., Davis, D.M., Mandelboim, O., Chen, B.K., Strominger, J.L., and Baltimore, D. The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells. Immunity 10, 661-71 (1999).
    • (1999) Immunity , vol.10 , pp. 661-671
    • Cohen, G.B.1    Gandhi, R.T.2    Davis, D.M.3    Mandelboim, O.4    Chen, B.K.5    Strominger, J.L.6    Baltimore, D.7
  • 67
    • 0034879087 scopus 로고    scopus 로고
    • Biphasic response of NK cells expressing both activating and inhibitory killer Ig-like receptors
    • Warren, H.S., Campbell, A.J., Waldron, J.C., and Lanier, L.L. Biphasic response of NK cells expressing both activating and inhibitory killer Ig-like receptors. Int. Immunol. 13, 1043-1052 (2001).
    • (2001) Int. Immunol. , vol.13 , pp. 1043-1052
    • Warren, H.S.1    Campbell, A.J.2    Waldron, J.C.3    Lanier, L.L.4
  • 68
    • 0033932001 scopus 로고    scopus 로고
    • Recovery, persistence, and sequelae in hepatitis C virus infection: A perspective on long-term outcome
    • Alter, H.J. and Seeff, L.B. Recovery, persistence, and sequelae in hepatitis C virus infection: A perspective on long-term outcome. Semin. Liver Dis. 20, 17-35 (2000).
    • (2000) Semin. Liver Dis. , vol.20 , pp. 17-35
    • Alter, H.J.1    Seeff, L.B.2
  • 69
    • 0033060563 scopus 로고    scopus 로고
    • Global surveillance and control of hepatitis C. Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium
    • Global surveillance and control of hepatitis C. Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium. J. Viral Hepat. 6, 35-47 (1999).
    • (1999) J. Viral Hepat. , vol.6 , pp. 35-47
  • 70
    • 0025313177 scopus 로고
    • Cmv-1, a genetic locus that controls murine cytomegalovirus replication in the spleen
    • Scalzo, A.A., Fitzgerald, N.A., Simmons, A., La Vista, A.B., and Shellam, G.R. Cmv-1, a genetic locus that controls murine cytomegalovirus replication in the spleen. J. Exp. Med. 171, 1469-1483 (1990).
    • (1990) J. Exp. Med. , vol.171 , pp. 1469-1483
    • Scalzo, A.A.1    Fitzgerald, N.A.2    Simmons, A.3    La Vista, A.B.4    Shellam, G.R.5
  • 71
    • 0032528340 scopus 로고    scopus 로고
    • Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition
    • Winter, C.C., Gumperz, J.E., Parham, P., Long, E.O., and Wagtmann, N. Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition. J. Immunol. 161, 571-577 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 571-577
    • Winter, C.C.1    Gumperz, J.E.2    Parham, P.3    Long, E.O.4    Wagtmann, N.5
  • 72
    • 0033214660 scopus 로고    scopus 로고
    • Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties
    • Maenaka, K., Juji, T., Nakayama, T. et al. Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties. J. Biol. Chem. 274, 28329-28334 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 28329-28334
    • Maenaka, K.1    Juji, T.2    Nakayama, T.3
  • 73
    • 0034213423 scopus 로고    scopus 로고
    • Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand
    • Boyington, J.C., Motyka, S.A., Schuck, P., Brooks, A.G., and Sun, P.D. Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand. Nature 405, 537-543 (2000). The first cocrystal of KIR with its HLA-C ligand. This paper provided a structural explanation for many of the biological features of KIR that had been previously observed.
    • (2000) Nature , vol.405 , pp. 537-543
    • Boyington, J.C.1    Motyka, S.A.2    Schuck, P.3    Brooks, A.G.4    Sun, P.D.5
  • 74
    • 17144363242 scopus 로고    scopus 로고
    • Understanding how combinations of HLA and KIR genes influence disease
    • Rajagopalan, S. and Long, E.O. Understanding how combinations of HLA and KIR genes influence disease. J. Exp. Med. 201, 1025-1029 (2005).
    • (2005) J. Exp. Med. , vol.201 , pp. 1025-1029
    • Rajagopalan, S.1    Long, E.O.2
  • 75
    • 0036865730 scopus 로고    scopus 로고
    • NK cell-mediated lysis of autologous HCMV-infected skin fibroblasts is highly variable among NK cell clones and polyclonal NK cell lines
    • Carr, W.H., Little, A.M., Mocarski, E., and Parham, P. NK cell-mediated lysis of autologous HCMV-infected skin fibroblasts is highly variable among NK cell clones and polyclonal NK cell lines. Clin. Immunol. 105, 126-140 (2002).
    • (2002) Clin. Immunol. , vol.105 , pp. 126-140
    • Carr, W.H.1    Little, A.M.2    Mocarski, E.3    Parham, P.4
  • 76
    • 9444273448 scopus 로고    scopus 로고
    • Imprint of human cytomegalovirus infection on the NK cell receptor repertoire
    • Guma, M., Angulo, A., Vilches, C., Gomez-Lozano, N., Malats, N., and Lopez-Botet, M. Imprint of human cytomegalovirus infection on the NK cell receptor repertoire. Blood 104, 3664-3671 (2004).
    • (2004) Blood , vol.104 , pp. 3664-3671
    • Guma, M.1    Angulo, A.2    Vilches, C.3    Gomez-Lozano, N.4    Malats, N.5    Lopez-Botet, M.6
  • 77
    • 10744232423 scopus 로고    scopus 로고
    • Expression of KIR2DL1 on the entire NK cell population: A possible novel immunodeficiency syndrome
    • Gazit, R., Garty, B.Z., Monselise, Y. et al. Expression of KIR2DL1 on the entire NK cell population: A possible novel immunodeficiency syndrome. Blood 103, 1965-1966 (2004).
    • (2004) Blood , vol.103 , pp. 1965-1966
    • Gazit, R.1    Garty, B.Z.2    Monselise, Y.3
  • 78
    • 0031573144 scopus 로고    scopus 로고
    • Natural killer cell cytokine production, not cytotoxicity, contributes to resistance against blood-stage Plasmodium chabaudi AS infection
    • Mohan, K., Moulin, P. and Stevenson, M. M. Natural killer cell cytokine production, not cytotoxicity, contributes to resistance against blood-stage Plasmodium chabaudi AS infection. J. Immunol. 159, 4990-4998 (1997).
    • (1997) J. Immunol. , vol.159 , pp. 4990-4998
    • Mohan, K.1    Moulin, P.2    Stevenson, M.M.3
  • 79
    • 0242578717 scopus 로고    scopus 로고
    • Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes
    • Artavanis-Tsakonas, K., Eleme, K., McQueen, K.L., Cheng, N.W., Parham, P., Davis, D.M., and Riley, E.M. Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes. J. Immunol. 171, 5396-5405 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 5396-5405
    • Artavanis-Tsakonas, K.1    Eleme, K.2    McQueen, K.L.3    Cheng, N.W.4    Parham, P.5    Davis, D.M.6    Riley, E.M.7
  • 81
    • 20444409135 scopus 로고    scopus 로고
    • Latest advances in understanding pre-eclampsia
    • Redman, C.W. and Sargent, I.L. Latest advances in understanding pre-eclampsia. Science 308, 1592-1524 (2005).
    • (2005) Science , vol.308 , pp. 1592-11524
    • Redman, C.W.1    Sargent, I.L.2
  • 82
    • 0034041995 scopus 로고    scopus 로고
    • Surface expression of HLA-C antigen by human extravillous trophoblast
    • King, A., Burrows, T.D., Hiby, S.E. et al. Surface expression of HLA-C antigen by human extravillous trophoblast. Placenta 21, 376-387 (2000).
    • (2000) Placenta , vol.21 , pp. 376-387
    • King, A.1    Burrows, T.D.2    Hiby, S.E.3
  • 83
    • 0034075580 scopus 로고    scopus 로고
    • HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells
    • King, A., Allan, D.S., Bowen, M. et al. HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells. Eur. J. Immunol. 30, 1623-1631 (2000).
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1623-1631
    • King, A.1    Allan, D.S.2    Bowen, M.3
  • 84
    • 7244234068 scopus 로고    scopus 로고
    • Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success
    • Hiby, S.E., Walker, J.J., O'Shaughnessy, K.M., Redman, C.W., Carrington, M., Trowsdale, J., and Moffett, A. Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. J. Exp. Med. 200, 957-965 (2004).
    • (2004) J. Exp. Med. , vol.200 , pp. 957-965
    • Hiby, S.E.1    Walker, J.J.2    O'Shaughnessy, K.M.3    Redman, C.W.4    Carrington, M.5    Trowsdale, J.6    Moffett, A.7
  • 85
    • 3343015492 scopus 로고    scopus 로고
    • Role of a KIR/HLA-C allorecognition system in pregnancy
    • Varla-Leftherioti, M. Role of a KIR/HLA-C allorecognition system in pregnancy. J. Reprod. Immunol. 62, 19-27 (2004).
    • (2004) J. Reprod. Immunol. , vol.62 , pp. 19-27
    • Varla-Leftherioti, M.1
  • 86
    • 0037951596 scopus 로고    scopus 로고
    • Natural killer (NK) cell receptors' repertoire in couples with recurrent spontaneous abortions
    • Varla-Leftherioti, M., Spyropoulou-Vlachou, M., Niokou, D. et al. Natural killer (NK) cell receptors' repertoire in couples with recurrent spontaneous abortions. Am. J. Reprod. Immunol. 49, 183-191 (2003).
    • (2003) Am. J. Reprod. Immunol. , vol.49 , pp. 183-191
    • Varla-Leftherioti, M.1    Spyropoulou-Vlachou, M.2    Niokou, D.3
  • 87
    • 0035927054 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis
    • Yen, J.H., Moore, B.E., Nakajima, T., Scholl, D., Schaid, D.J., Weyand, C.M., and Goronzy, J.J. Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis. J. Exp. Med. 193, 1159-1167 (2001). This paper was the first to describe a genetic association of KIR with a human disease. The authors have also shown in vivo data supporting the expression of the disease association genes on T cells.
    • (2001) J. Exp. Med. , vol.193 , pp. 1159-1167
    • Yen, J.H.1    Moore, B.E.2    Nakajima, T.3    Scholl, D.4    Schaid, D.J.5    Weyand, C.M.6    Goronzy, J.J.7
  • 88
    • 9144251663 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of CD4 T cells expressing killer Ig-like receptors
    • van Bergen, J., Thompson, A., van der Slik, A., Ottenhoff, T.H., Gussekloo, J., and Koning, F. Phenotypic and functional characterization of CD4 T cells expressing killer Ig-like receptors. J. Immunol. 173, 6719-6726 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 6719-6726
    • Van Bergen, J.1    Thompson, A.2    Van Der Slik, A.3    Ottenhoff, T.H.4    Gussekloo, J.5    Koning, F.6
  • 90
    • 4644239414 scopus 로고    scopus 로고
    • Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms
    • Snyder, M.R., Nakajima, T., Leibson, P.J., Weyand, C.M., and Goronzy, J.J. Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms. J. Immunol. 173, 3725-3731 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 3725-3731
    • Snyder, M.R.1    Nakajima, T.2    Leibson, P.J.3    Weyand, C.M.4    Goronzy, J.J.5
  • 91
    • 0043269270 scopus 로고    scopus 로고
    • De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes
    • Nakajima, T., Goek, O., Zhang, X., Kopecky, S.L., Frye, R.L., Goronzy, J.J., and Weyand, C.M. De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes. Circ. Res. 93, 106-113 (2003).
    • (2003) Circ. Res. , vol.93 , pp. 106-113
    • Nakajima, T.1    Goek, O.2    Zhang, X.3    Kopecky, S.L.4    Frye, R.L.5    Goronzy, J.J.6    Weyand, C.M.7
  • 92
    • 4043108432 scopus 로고    scopus 로고
    • Gene for the activating natural killer cell receptor, KIR2DS1, is associated with susceptibility to psoriasis vulgaris
    • Luszczek, W., Manczak, M., Cislo, M., Nockowski, P., Wisniewski, A., Jasek, M., and Kusnierczyk, P. Gene for the activating natural killer cell receptor, KIR2DS1, is associated with susceptibility to psoriasis vulgaris. Hum. Immunol. 65, 758-766 (2004).
    • (2004) Hum. Immunol. , vol.65 , pp. 758-766
    • Luszczek, W.1    Manczak, M.2    Cislo, M.3    Nockowski, P.4    Wisniewski, A.5    Jasek, M.6    Kusnierczyk, P.7
  • 93
    • 2442532567 scopus 로고    scopus 로고
    • Genetic polymorphisms of killer cell immunoglobulin-like receptors are associated with susceptibility to psoriasis vulgaris
    • Suzuki, Y., Hamamoto, Y., Ogasawara, Y., Ishikawa, K., Yoshikawa, Y., Sasazuki, T., and Muto, M. Genetic polymorphisms of killer cell immunoglobulin-like receptors are associated with susceptibility to psoriasis vulgaris. J. Invest. Dermatol. 122, 1133-1136 (2004).
    • (2004) J. Invest. Dermatol. , vol.122 , pp. 1133-1136
    • Suzuki, Y.1    Hamamoto, Y.2    Ogasawara, Y.3    Ishikawa, K.4    Yoshikawa, Y.5    Sasazuki, T.6    Muto, M.7
  • 94
    • 4644229910 scopus 로고    scopus 로고
    • Heterozygote advantage in autoimmune disease: Hierarchy of protection/susceptibility conferred by HLA and Killer Ig-Like receptor combinations in psoriatic arthritis
    • Nelson, G.W., Martin, M.P., Gladman, D., Wade, J., Trowsdale, J., and Carrington, M. Heterozygote advantage in autoimmune disease: Hierarchy of protection/susceptibility conferred by HLA and Killer Ig-Like receptor combinations in psoriatic arthritis. J. Immunol. 173, 4273-4276 (2004). This paper proposes a model for autoimmunity based on activating and inhibitory KIR genotypes, as a type of "molecular rheostat."
    • (2004) J. Immunol. , vol.173 , pp. 4273-4276
    • Nelson, G.W.1    Martin, M.P.2    Gladman, D.3    Wade, J.4    Trowsdale, J.5    Carrington, M.6
  • 95
    • 0141532166 scopus 로고    scopus 로고
    • KIR in type 1 diabetes: Disparate distribution of activating and inhibitory natural killer cell receptors in patients versus HLA-matched control subjects
    • van der Slik, A.R., Koeleman, B.P., Verduijn, W., Bruining, G.J., Roep, B.O., and Giphart, M.J. KIR in type 1 diabetes: Disparate distribution of activating and inhibitory natural killer cell receptors in patients versus HLA-matched control subjects. Diabetes 52, 2639-2642 (2003).
    • (2003) Diabetes , vol.52 , pp. 2639-2642
    • Van Der Slik, A.R.1    Koeleman, B.P.2    Verduijn, W.3    Bruining, G.J.4    Roep, B.O.5    Giphart, M.J.6
  • 97
    • 0027300176 scopus 로고
    • Clonal diseases of large granular lymphocytes
    • Loughran, T.P., Jr. Clonal diseases of large granular lymphocytes. Blood 82, 1-14 (1993).
    • (1993) Blood , vol.82 , pp. 1-14
    • Loughran Jr., T.P.1
  • 98
    • 0032881057 scopus 로고    scopus 로고
    • A long-term study of patients with chronic natural killer cell lymphocytosis
    • Rabbani, G.R., Phyliky, R.L., and Tefferi, A. A long-term study of patients with chronic natural killer cell lymphocytosis. Br. J. Haematol. 106, 960-966 (1999).
    • (1999) Br. J. Haematol. , vol.106 , pp. 960-966
    • Rabbani, G.R.1    Phyliky, R.L.2    Tefferi, A.3
  • 99
    • 0037353903 scopus 로고    scopus 로고
    • Demonstration of aberrant T-cell and natural killer-cell antigen expression in all cases of granular lymphocytic leukaemia
    • Morice, W.G., Kurtin, P.J., Leibson, P.J., Tefferi, A., and Hanson, C.A. Demonstration of aberrant T-cell and natural killer-cell antigen expression in all cases of granular lymphocytic leukaemia. Br. J. Haematol. 120, 1026-1036 (2003).
    • (2003) Br. J. Haematol. , vol.120 , pp. 1026-1036
    • Morice, W.G.1    Kurtin, P.J.2    Leibson, P.J.3    Tefferi, A.4    Hanson, C.A.5
  • 100
    • 14144256444 scopus 로고    scopus 로고
    • Human leucocyte antigen class I and killer immunoglobulin-like receptor expression patterns in T-cell large granular lymphocyte leukaemia
    • Nowakowski, G.S., Morice, W.G., Phyliky, R.L., Li, C.Y., and Tefferi, A. Human leucocyte antigen class I and killer immunoglobulin-like receptor expression patterns in T-cell large granular lymphocyte leukaemia. Br. J. Haematol. 128, 490-492 (2005).
    • (2005) Br. J. Haematol. , vol.128 , pp. 490-492
    • Nowakowski, G.S.1    Morice, W.G.2    Phyliky, R.L.3    Li, C.Y.4    Tefferi, A.5
  • 101
    • 0033611476 scopus 로고    scopus 로고
    • Pure red-cell aplasia associated with clonal expansion of granular lymphocytes expressing killer-cell inhibitory receptors
    • Handgretinger, R., Geiselhart, A., Moris, A., Grau, R., Teuffel, O., Bethge, W., Kanz, L., and Fisch, P. Pure red-cell aplasia associated with clonal expansion of granular lymphocytes expressing killer-cell inhibitory receptors. N. Engl. J. Med. 340, 278-284 (1999).
    • (1999) N. Engl. J. Med. , vol.340 , pp. 278-284
    • Handgretinger, R.1    Geiselhart, A.2    Moris, A.3    Grau, R.4    Teuffel, O.5    Bethge, W.6    Kanz, L.7    Fisch, P.8
  • 102
    • 0035348133 scopus 로고    scopus 로고
    • High expression of the ILT2 (LIR-1) inhibitory receptor for major histocompatibility complex class I molecules on clonal expansions of T large granular lymphocytes in asymptomatic patients
    • Casado, L.F., Granados, E., Algara, P., Navarro, F., Martinez-Frejo, M.C., Lopez-and Botet, M. High expression of the ILT2 (LIR-1) inhibitory receptor for major histocompatibility complex class I molecules on clonal expansions of T large granular lymphocytes in asymptomatic patients. Haematologica 86, 457-463 (2001).
    • (2001) Haematologica , vol.86 , pp. 457-463
    • Casado, L.F.1    Granados, E.2    Algara, P.3    Navarro, F.4    Martinez-Frejo, M.C.5    Lopez-Botet, M.6
  • 103
    • 0042942800 scopus 로고    scopus 로고
    • Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes
    • Zambello, R., Falco, M., Della Chiesa, M. et al. Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes. Blood 102, 1797-1805 (2003).
    • (2003) Blood , vol.102 , pp. 1797-1805
    • Zambello, R.1    Falco, M.2    Della Chiesa, M.3
  • 104
    • 1942456857 scopus 로고    scopus 로고
    • Dysregulated NK receptor expression in patients with lymphoproliferative disease of granular lymphocytes
    • Epling-Burnette, P.K., Painter, J.S., Chaurasia, P., Bai, F., Wei, S., Djeu, J.Y., and Loughran, T.P. Jr. Dysregulated NK receptor expression in patients with lymphoproliferative disease of granular lymphocytes. Blood 103, 3431-3439 (2004).
    • (2004) Blood , vol.103 , pp. 3431-3439
    • Epling-Burnette, P.K.1    Painter, J.S.2    Chaurasia, P.3    Bai, F.4    Wei, S.5    Djeu, J.Y.6    Loughran Jr., T.P.7
  • 106
    • 11144353772 scopus 로고    scopus 로고
    • CD158k/KIR3DL2 is a new phenotypic marker of Sezary cells: Relevance for the diagnosis and follow-up of Sezary syndrome
    • Poszepczynska-Guigne, E., Schiavon, V., D'Incan, M. et al. CD158k/KIR3DL2 is a new phenotypic marker of Sezary cells: relevance for the diagnosis and follow-up of Sezary syndrome. J. Invest. Dermatol. 122, 820-823 (2004).
    • (2004) J. Invest. Dermatol. , vol.122 , pp. 820-823
    • Poszepczynska-Guigne, E.1    Schiavon, V.2    D'Incan, M.3
  • 108
    • 0037093066 scopus 로고    scopus 로고
    • Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia
    • Costello, R.T., Sivori, S., Marcenaro, E. et al. Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia. Blood 99, 3661-3667 (2002).
    • (2002) Blood , vol.99 , pp. 3661-3667
    • Costello, R.T.1    Sivori, S.2    Marcenaro, E.3
  • 109
    • 11144294699 scopus 로고    scopus 로고
    • Identification of natural killer cell receptor phenotypes associated with leukemia
    • Verheyden, S., Bernier, M. and Demanet, C. Identification of natural killer cell receptor phenotypes associated with leukemia. Leukemia 18, 2002200-7 (2004).
    • (2004) Leukemia , vol.18 , pp. 2002200-7
    • Verheyden, S.1    Bernier, M.2    Demanet, C.3
  • 110
    • 20844444935 scopus 로고    scopus 로고
    • Protective effect of the HLA-Bw4I80 epitope and the Killer Cell Immunoglobulin-Like Receptor 3DS1 gene against the development of hepatocellular carcinoma in patients with hepatitis C virus infection
    • Lopez-Vazquez, A., Rodrigo, L., Martinez-Borra, J. et al. Protective effect of the HLA-Bw4I80 epitope and the Killer Cell Immunoglobulin-Like Receptor 3DS1 gene against the development of hepatocellular carcinoma in patients with hepatitis C virus infection. J. Infect. Dis. 192, 162-165 (2005).
    • (2005) J. Infect. Dis. , vol.192 , pp. 162-165
    • Lopez-Vazquez, A.1    Rodrigo, L.2    Martinez-Borra, J.3
  • 111
    • 11944249879 scopus 로고    scopus 로고
    • Genetic polymorphism of NK receptors and their ligands in melanoma patients: Prevalence of inhibitory over activating signals
    • Naumova, E., Mihaylova, A., Stoitchkov, K., Ivanova, M., Quin, L., and Toneva, M. Genetic polymorphism of NK receptors and their ligands in melanoma patients: Prevalence of inhibitory over activating signals. Cancer Immunol. Immunother. 54, 172-178 (2005).
    • (2005) Cancer Immunol. Immunother. , vol.54 , pp. 172-178
    • Naumova, E.1    Mihaylova, A.2    Stoitchkov, K.3    Ivanova, M.4    Quin, L.5    Toneva, M.6
  • 112
    • 0037268349 scopus 로고    scopus 로고
    • Selective reduction of natural killer cells and T cells expressing inhibitory receptors for MHC class I in the livers of patients with hepatic malignancy
    • Norris, S., Doherty, D.G., Curry, M., McEntee, G., Traynor, O., Hegarty, J.E., and O'Farrelly, C. Selective reduction of natural killer cells and T cells expressing inhibitory receptors for MHC class I in the livers of patients with hepatic malignancy. Cancer Immunol. Immunother. 52, 53-58 (2003).
    • (2003) Cancer Immunol. Immunother. , vol.52 , pp. 53-58
    • Norris, S.1    Doherty, D.G.2    Curry, M.3    McEntee, G.4    Traynor, O.5    Hegarty, J.E.6    O'Farrelly, C.7
  • 113
    • 10644285782 scopus 로고    scopus 로고
    • Natural killer cells infiltrating colorectal cancer and MHC class I expression
    • Sandel, M.H., Speetjens, F.M., Menon, A.G. et al. Natural killer cells infiltrating colorectal cancer and MHC class I expression. Mol. Immunol. 42, 541-546 (2005).
    • (2005) Mol. Immunol. , vol.42 , pp. 541-546
    • Sandel, M.H.1    Speetjens, F.M.2    Menon, A.G.3
  • 114
    • 0030962059 scopus 로고    scopus 로고
    • Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor
    • Ikeda, H., Lethe, B., Lehmann, F. et al. Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor. Immunity 6, 199-208 (1997).
    • (1997) Immunity , vol.6 , pp. 199-208
    • Ikeda, H.1    Lethe, B.2    Lehmann, F.3
  • 115
    • 0032101973 scopus 로고    scopus 로고
    • Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, gamma delta T cells, and antigen-specific CTL
    • Bakker, A.B., Phillips, J.H., Figdor, C.G., and Lanier, L.L. Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, gamma delta T cells, and antigen-specific CTL. J. Immunol. 160, 5239-5245 (1998).
    • (1998) J. Immunol. , vol.160 , pp. 5239-5245
    • Bakker, A.B.1    Phillips, J.H.2    Figdor, C.G.3    Lanier, L.L.4
  • 116
    • 4344624611 scopus 로고    scopus 로고
    • Prevalent expression of the immunostimulatory MHC class I chainrelated molecule is counteracted by shedding in prostate cancer
    • Wu, J.D., Higgins, L.M., Steinle, A., Cosman, D., Haugk, K., Plymate, S.R. Prevalent expression of the immunostimulatory MHC class I chainrelated molecule is counteracted by shedding in prostate cancer. J. Clin. Invest. 114, 560-568 (2004).
    • (2004) J. Clin. Invest. , vol.114 , pp. 560-568
    • Wu, J.D.1    Higgins, L.M.2    Steinle, A.3    Cosman, D.4    Haugk, K.5    Plymate, S.R.6
  • 117
    • 0037126310 scopus 로고    scopus 로고
    • Tumor-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
    • Groh, V., Wu, J., Yee, C., and Spies, T. Tumor-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature 419, 734-738 (2002).
    • (2002) Nature , vol.419 , pp. 734-738
    • Groh, V.1    Wu, J.2    Yee, C.3    Spies, T.4
  • 118
    • 0033168770 scopus 로고    scopus 로고
    • Role of natural killer cell allo-reactivity in HLA-mismatched hematopoietic stem cell transplantation
    • Ruggeri, L., Capanni, M., Casucci, M. et al. Role of natural killer cell allo-reactivity in HLA-mismatched hematopoietic stem cell transplantation. Blood, 94, 333-9 (1999).
    • (1999) Blood , vol.94 , pp. 333-339
    • Ruggeri, L.1    Capanni, M.2    Casucci, M.3
  • 119
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • Ruggeri, L., Capanni, M., Urbani, E. et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 295, 2097-2100 (2002). This paper demonstrated the role of NK cell autoreactivity following bone marrow transplantation, and showed that the potential for NK cell alloreactivity correlated with a multilevel therapeutic benefit in haploidentical bne marrow transplantation for AML.
    • (2002) Science , vol.295 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3
  • 120
    • 20444394742 scopus 로고    scopus 로고
    • Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes
    • Hsu, K.C., Keever-Taylor, C.A., Wilton, A., Pinto, C., Heller, G., Arkun, K., O'Reilly, R.J., Horowitz, M.M., Dupont, B. Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes. Blood 105, 4878-84 (2005).
    • (2005) Blood , vol.105 , pp. 4878-4884
    • Hsu, K.C.1    Keever-Taylor, C.A.2    Wilton, A.3    Pinto, C.4    Heller, G.5    Arkun, K.6    O'Reilly, R.J.7    Horowitz, M.M.8    Dupont, B.9
  • 121
    • 23744449591 scopus 로고    scopus 로고
    • A defined donor activating natural killer cell receptor genotype protects against leukemic relapse after related HLA-identical hematopoietic stem cell transplantation
    • Verheyden, S., Schots, R., Duquet, W., and Demanet, C. A defined donor activating natural killer cell receptor genotype protects against leukemic relapse after related HLA-identical hematopoietic stem cell transplantation. Leukemia 19, 1446-1451 (2005).
    • (2005) Leukemia , vol.19 , pp. 1446-1451
    • Verheyden, S.1    Schots, R.2    Duquet, W.3    Demanet, C.4
  • 122
    • 0032080398 scopus 로고    scopus 로고
    • Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation
    • Asai, O., Longo, D.L., Tian, Z.G., Hornung, R.L., Taub, D.D., Ruscetti, F.W., and Murphy, W.J. Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation. J. Clin. Invest. 101, 1835-1842 (1998).
    • (1998) J. Clin. Invest. , vol.101 , pp. 1835-1842
    • Asai, O.1    Longo, D.L.2    Tian, Z.G.3    Hornung, R.L.4    Taub, D.D.5    Ruscetti, F.W.6    Murphy, W.J.7
  • 124
    • 10744230735 scopus 로고    scopus 로고
    • Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors
    • Giebel, S., Locatelli, F., Lamparelli, T. et al. Survival advantage with KIR ligand incompatibility in hematopoietic stem cell transplantation from unrelated donors. Blood 102, 814-819 (2003).
    • (2003) Blood , vol.102 , pp. 814-819
    • Giebel, S.1    Locatelli, F.2    Lamparelli, T.3
  • 125
    • 0037111776 scopus 로고    scopus 로고
    • Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor
    • Davies, S.M., Ruggieri, L., DeFor, T., Wagner, J.E., Weisdorf, D.J., Miller, J.S., Velardi, A., and Blazar, B.R. Evaluation of KIR ligand incompatibility in mismatched unrelated donor hematopoietic transplants. Killer immunoglobulin-like receptor. Blood 100, 3825-3827 (2002).
    • (2002) Blood , vol.100 , pp. 3825-3827
    • Davies, S.M.1    Ruggieri, L.2    DeFor, T.3    Wagner, J.E.4    Weisdorf, D.J.5    Miller, J.S.6    Velardi, A.7    Blazar, B.R.8
  • 126
    • 20144377362 scopus 로고    scopus 로고
    • Natural killer cell HLA-C epitopes and killer cell immunoglobulin-like receptors both influence outcome of mismatched unrelated donor bone marrow transplants
    • De Santis, D., Bishara, A., Witt, C.S., Nagler, A., Brautbar, C., Slavin, S., and Christiansen, F.T. Natural killer cell HLA-C epitopes and killer cell immunoglobulin-like receptors both influence outcome of mismatched unrelated donor bone marrow transplants. Tissue Antigens 65, 519-528 (2005).
    • (2005) Tissue Antigens , vol.65 , pp. 519-528
    • De Santis, D.1    Bishara, A.2    Witt, C.S.3    Nagler, A.4    Brautbar, C.5    Slavin, S.6    Christiansen, F.T.7
  • 127
    • 20144388509 scopus 로고    scopus 로고
    • Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
    • Miller, J.S., Soignier, Y., Panoskaltsis-Mortari, A. et al. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Blood 105, 3051-3057 (2005). This paper demonstrates that it is safe to adoptively transfer alloreactive NK cells into patients with malignancy.
    • (2005) Blood , vol.105 , pp. 3051-3057
    • Miller, J.S.1    Soignier, Y.2    Panoskaltsis-Mortari, A.3
  • 128
    • 4644249118 scopus 로고    scopus 로고
    • The critical role of residues 43R and 44Q of carcinoembryonic antigen cell adhesion molecules-1 in the protection from killing by human NK cells
    • Markel, G., Gruda, R., Achdout, H., Katz, G., Nechama, M., Blumberg, R.S., Kammerer, R., Zimmermann, W., and Mandelboim, O. The critical role of residues 43R and 44Q of carcinoembryonic antigen cell adhesion molecules-1 in the protection from killing by human NK cells. J. Immunol. 173, 3732-3739 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 3732-3739
    • Markel, G.1    Gruda, R.2    Achdout, H.3    Katz, G.4    Nechama, M.5    Blumberg, R.S.6    Kammerer, R.7    Zimmermann, W.8    Mandelboim, O.9
  • 129
    • 17044400963 scopus 로고    scopus 로고
    • Opposing effect of IFNgamma and IFNalpha on expression of NKG2 receptors: Negative regulation of IFNgamma on NK cells
    • Zhang, C., Zhang, J., Sun, R., Feng, J., Wei, H., and Tian, Z. Opposing effect of IFNgamma and IFNalpha on expression of NKG2 receptors: Negative regulation of IFNgamma on NK cells. Int. Immunopharmacol. 5, 1057-1067 (2005).
    • (2005) Int. Immunopharmacol. , vol.5 , pp. 1057-1067
    • Zhang, C.1    Zhang, J.2    Sun, R.3    Feng, J.4    Wei, H.5    Tian, Z.6
  • 130
    • 22044456688 scopus 로고    scopus 로고
    • Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells
    • Imai, C., Iwamoto, S., and Campana, D. Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells. Blood 106, 376-383 (2005).
    • (2005) Blood , vol.106 , pp. 376-383
    • Imai, C.1    Iwamoto, S.2    Campana, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.