Conservation and variation in human and common chimpanzee CD94 and NKG2 genes

Journal of Immunology

Volumn 168, Issue 1, 2002, Pages 240-252

  Shum, B P ^a   Flodin, L R ^a   Muir, D G ^a   Rajalingam, R ^a   Khakoo, S I ^a   Cleland, S ^a   Guethlein, L A ^a   Uhrberg, M ^a   Parham, P ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD94 ANTIGEN; HLA ANTIGEN CLASS 1;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHIMPANZEE; DNA DETERMINATION; GENE DUPLICATION; GENETIC CONSERVATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DOMAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSLATION REGULATION;

HOMO SAPIENS; PAN TROGLODYTES;

EID: 0036136320     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.1.240     Document Type: Article

References (68)

1. NK cell receptors
2. Chromosomal localization of the human natural killer cell class I receptor family genes to 19q13.4 by fluorescence in situ hybridization
3. A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors
4. Organization of the leukocyte receptor cluster (LRC) on human chromosome 19q13.4
5. Plasticity in the organization and sequences of human KIR/ILT gene families
6. DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells
7. A multigene family on human chromosome 12 encodes natural killer-cell lectins
8. The human natural killer gene complex is located on chromosome 12p12-13
9. The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex
10. Sequence analysis of a 62-kb region overlapping the human KLRC cluster of genes
11. Linkage of the NKG2 and CD94 receptor genes to D12S77 in the human natural killer gene complex
12. CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes
13. Human NK cell receptors involved in MHC class I recognition are disulfidelinked heterodimers of CD94 and NKG2 subunits
14. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
15. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2A, confers protection from natural killer cell-mediated lysis
16. HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A
17. HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: Preferential response to an HLA-Gderived nonamer
18. Specific recognition of HLA-E, but not classical, HLA class I molecules by soluble CD94/NKG2A and NK cells
19. Immunoreceptor tyrosine-based inhibition motifs
20. The CD94 and NKG2-A C-type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules
21. NK cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C
22. The activating form of CD94 receptor complex: CD94 covalently associates with the Kp39 protein that represents the product of the NKG2-C gene
23. Activation of NK cells and T cells by NKG2D, a receptor for stressinducible MICA
24. Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells
25. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
26. An activating immunoreceptor complex formed by NKG2D and DAP10
27. Association of DAP12 with activating CD94/NKG2C NK cell receptors
28. HLA class I recognition by killer cell Ig-like receptors
29. Human diversity in killer cell inhibitory receptor genes
30. Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors
31. Evidence for recombination as a mechanism for KIR diversification
32. Different N.K. cell surface phenotypes defined by the DX9 antibody are due to KIR3DLgene polymorphism
33. Identification of seventeen novel KIR variants: Fourteen of them from two non-Caucasian donors
34. Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans
35. Short KIR haplotypes in pygmy chimpanzee (bonobo) resemble the conserved framework of diverse human KIR haplotypes
36. Comparison of class I MHC alleles in humans and apes
37. RNA splice junctions of different classes of eukaryotes: Sequence statistics and functional implications in gene expression
38. An alternatively spliced form of the human CD94 gene
39. Genomic structure, chromosome location, and alternative splicing of the human NKG2A gene
40. + T cell clone upon the aggregation of an activatory CD94/kp39 heterodimer
41. Natural killer lectin-like receptors have divergent carboxy-termini, distinct from C-type lectins
42. Cloning of NKG2-F, a new member of the NKG2 family of human natural killer cell receptor genes
43. Nomenclature for factors of the HLA system, 2000
44. Allelic repertoire of the human MHC class I MICA gene
45. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules
46. Characterization of rhesus monkey CD94/NKG2 family members and identification of novel transmembrane-deleted forms of NKG2-A, B, C, and D
47. Selective expression of NKG2-A and NKG2-C mRNAs and novel alternative splicing of 5′ exons in rhesus monkey decidua
48. Cloning of a mouse homolog of CD94 extends the family of C-type lectins on murine natural killer cells
49. Murine Nkg2d and Cd94 are clustered within the natural killer complex and are expressed independently in natural killer cells
50. Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b)
51. Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells
52. Molecular cloning of mouse NKG2A and C
53. Cloning of murine NKG2A, B and C: Second family of C-type lectin receptors on murine NK cells
54. Molecular characterization of a gene in the rat homologous to human CD94
55. Two genes in the rat homologous to human NKG2
56. Molecular characterization of rat NKR-P2, a lectin-like receptor expressed by NK cells and resting T cells
57. The MHC E locus in macaques is polymorphic and is conserved between macaques and humans
58. The Qa-1b molecule binds to a large subpopulation of murine NK cells
59. Qabinds conserved class I leader peptides derived from several mammalian species
60. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice
61. Ligands for the murine NKG2D receptor: Expression by tumor cells and activation of NK cells and macrophages
62. Genomic divergences between humans and other hominoids and the effective population size of the common ancestor of humans and chimpanzees
63. Structure of CD94 reveals a novel C-type lectin fold: Implications for the NK cell-associated CD94/NKG2 receptors
64. The Ly-49 family: Genes, proteins and recognition of class I MHC
65. Identification of a human member of the Ly-49 multigene family
66. Evolution of natural killer cell receptors, coexistence of functional Ly49 and KIR genes in baboons