The MAPK Kinase Kinase TAK1 Plays a Central Role in Coupling the Interleukin-1 Receptor to Both Transcriptional and RNA-targeted Mechanisms of Gene Regulation

Journal of Biological Chemistry

Volumn 276, Issue 5, 2001, Pages 3508-3516

  Holtmann, Helmut ^a   Enninga, Jost ^a   Kälble, Solveig ^a   Thiefes, Axel ^a   Dörrie, Anneke ^a   Broemer, Meike ^a   Winzen, Reinhard ^a   Wilhelm, Arno ^a   Ninomiya Tsuji, Jun ^b   Matsumoto, Kunihiro ^b   Resch, Klaus ^a   Kracht, Michael ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; GENES; PHYSIOLOGY; POLYPEPTIDES; PROTEINS; RNA;

KINASES; MUTANTS;

BIOCHEMISTRY;

BINDING PROTEIN; COMPLEMENTARY DNA; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; STRESS ACTIVATED PROTEIN KINASE; TAK BINDING PROTEIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG; CARRIER PROTEIN; CHEMOKINE RECEPTOR CXCR1; GLOBIN; MAP KINASE KINASE KINASE 7; MAP3K7IP1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TAB1 PROTEIN, MAPKKK ACTIVATOR, VERTEBRATE;

ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; INFLAMMATION; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; REPORTER GENE; TRANSCRIPTION REGULATION; WESTERN BLOTTING; BIOSYNTHESIS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; PROMOTER REGION; RNA STABILITY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CARRIER PROTEINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GLOBINS; HELA CELLS; HUMANS; INTERLEUKIN-8; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 4; MAP KINASE KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS (GENETICS); RECEPTORS, INTERLEUKIN-1; RECEPTORS, INTERLEUKIN-8A; RNA STABILITY; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0035793610     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M004376200     Document Type: Article

References (45)

1. Dinarello, C. (1996) Blood 87, 2095-2147
2. Baggiolini, M., and Clark-Lewis, I. (1992) FEBS Lett. 307, 97-101
3. Martin, M. U., and Falk, W. (1997) Eur. Cytokine Netw. 8, 5-17
4. O'Neill, L. A., and Greene, C. (1998) J. Leukoc. Biol. 63, 650-657
5. Kracht, M., Truong, O., Totty, N. F., Shiroo, M., and Saklatvala, J. (1994) J. Exp. Med. 180, 2017-2025
6. Freshney, N. W., Rawlinson, L., Guesdon, F., Jones, E., Cowley, S., Hsuan, J., and Saklatvala, J. (1994) Cell 78, 1039-1049
7. Davis, R. J. (1999) Biochem. Soc. Symp. 64, 1-12
8. Garrington, T. P., and Johnson, G. L. (1999) Curr. Opin. Cell Biol. 11, 211-218
9. Lee, F. S., Hagler, J., Chen, Z. J., and Maniatis, T. (1997) Cell 88, 213-222
10. Meyer, C. F., Wang, X., Chang, C., Templeton, D., and Tan, T. H. (1996) J. Biol. Chem. 271, 8971-8976
11. Zandi, E., and Karin, M. (1999) Mol. Cell. Biol. 19, 4547-4551
12. Zhao, Q., and Lee, F. S. (1999) J. Biol. Chem. 274, 8355-8358
13. Ninomiya-Tsuji, J., Kishimoto, K., Hiyama, A., Inoue, J., Cao, Z., and Matsumoto, K. (1999) Nature 398, 252-256
14. Sakurai, H., Miyoshi, H., Toriumi, W., and Sugita, T. (1999) J. Biol. Chem. 274, 10641-10648
15. Sakurai, H., Shigemori, N., Hasegawa, K., and Sugita, T. (1998) Biochem. Biophys. Res. Commun. 243, 545-549
16. Lin, X., Cunningham, E. T. Jr., Mu, Y., Geleziunas, R., and Greene, W. C. (1999) Immunity 10, 271-280
17. Holtmann, H., Winzen, R., Holland, P., Eickemeier, S., Hoffmann, E., Wallach, D., Malinin, N. L., Cooper, J. A., Resch, K., and Kracht, M. (1999) Mol. Cell. Biol. 19, 6742-6753
18. Malinin, N. L., Boldin, M. P., Kovalenko, A. V., and Wallach, D. (1997) Nature 385, 540-544
19. Song, H. Y., Regnier, C. H., Kirschning, C. J., Goeddel, D. V., and Rothe, M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 9792-9796
20. Baud, V., Liu, Z. G., Bennett, B., Suzuki, N., Xia, Y., and Karin, M. (1999) Genes Dev. 13, 1297-1308
21. Ichijo, H., Nishida, E., Irie, K., ten Dijke, P., Saitoh, M., Moriguchi, T., Takagi, M., Matsumoto, K., Miyazono, K., and Gotoh, Y. (1997) Science 275, 90-94
22. Lin, X., Mu, Y., Cunningham, E. T. Jr., Marcu, K. B., Geleziunas, R., and Greene, W. C. (1998) Mol. Cell. Biol. 18, 5899-5907
23. Nemoto, S., DiDonato, J. A., and Lin, A. (1998) Mol. Cell. Biol. 18, 7336-7343
24. Xia, Y., Wu, Z., Su, B., Murray, B., and Karin, M. (1998) Genes Dev. 12, 3369-3381
25. Karin, M., and Delhase, M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 9067-9069
26. Shirakabe, K., Yamaguchi, K., Shibuya, H., Irie, K., Matsuda, S., Moriguchi, T., Gotoh, Y., Matsumoto, K., and Nishida, E. (1997) J. Biol. Chem. 272, 8141-8144
27. Sano, Y., Harada, J., Tashiro, S., Gotoh-Mandeville, R., Maekawa, T., and Ishii, S. (1999) J. Biol. Chem. 274, 8949-8957
28. Shibuya, H., Iwata, H., Masuyama, N., Gotoh, Y., Yamaguchi, K., Irie, K., Matsumoto, K., Nishida, E., and Ueno, N. (1998) EMBO J. 17, 1019-1028
29. Yamaguchi, K., Shirakabe, K., Shibuya, H., Irie, K., Oishi, I., Ueno, N., Taniguchi, T., Nishida, E., and Matsumoto, K. (1995) Science 270, 2008-2011
30. Zhou, G., Lee, S. C., Yao, Z., and Tan, T. H. (1999) J. Biol. Chem. 274, 13133-13138
31. Letterio, J. J., and Roberts, A. B. (1998) Annu. Rev. Immunol. 16, 137-161
32. Song, X. Y., Gu, M., Jin, W. W., Klinman, D. M., and Wahl, S. M. (1998) J. Clin. Invest. 101, 2615-2621
33. Shibuya, H., Yamaguchi, K., Shirakabe, K., Tonegawa, A., Gotoh, Y., Ueno, N., Irie, K., Nishida, E., and Matsumoto, K. (1996) Science 272, 1179-1182
34. Winzen, R., Kracht, M., Ritter, B., Wilhelm, A., Chen, C.-Y. A., Shyu, A.-B., Müller, M., Gaestel, M., Resch, K., and Holtmann, H. (1999) EMBO J. 18, 4969-4980
35. Gossen, M., and Bujard, H. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5547-5551
36. Finch, A., Holland, P., Cooper, J. A., Saklatvala, J., and Kracht, M. (1997) FEBS Lett. 418, 144-148
37. Hanafusa, H., Ninomiya-Tsuji, J., Masuyama, N., Nishita, M., Fujisawa, J., Shibuya, H., Matsumoto, K., and Nishida, E. (1999) J. Biol. Chem. 274, 27161-27167
38. Moriguchi, T., Kuroyanagi, N., Yamaguchi, K., Gotoh, Y., Irie, K., Kano, T., Shirakabe, K., Muro, Y., Shibuya, H., Matsumoto, K., Nishida, E., and Hagiwara, M. (1996) J. Biol. Chem. 271, 13675-13679
39. Wang, W., Zhou, G., Hu, M. C.-T., Yao, Z., and Tan, T.-H. (1997) J. Biol. Chem. 272, 22771-22775
40. Krause, A., Holtmann, H., Eickemeier, S., Winzen, R., Szamel, M., Resch, K., Saklatvala, J., and Kracht, M. (1998) J. Biol. Chem. 273, 23681-23689
41. Ito, M., Yoshioka, K., Akechi, M., Yamashita, S., Takamatsu, N., Sugiyama, K., Hibi, M., Nakabeppu, Y., Shiba, T., and Yamamoto, K. I. (1999) Mol. Cell. Biol. 19, 7539-7548
42. Koyano, S., Ito, M., Takamatsu, N., Shiba, T., Yamamoto, K., and Yoshioka, K. (1999) FEBS Lett. 457, 385-388
43. Whitmarsh, A. J., Cavanagh, J., Tournier, C., Yasuda, J., and Davis, R. J. (1998) Science 281, 1671-1674
44. Whitmarsh, A. J., and Davis, R. J. (1998) Trends Biochem. Sci. 23, 481-485
45. Yasuda, J., Whitmarsh, A. J., Cavanagh, J., Sharma, M., and Davis, R. J. (1999) Mol. Cell. Biol. 19, 7245-7254