Intracellular free iron and acidic pathways mediate TNF-induced death of rat hepatoma cells

Apoptosis

Volumn 10, Issue 4, 2005, Pages 777-786

  Autelli, R ^a,b   Crepaldi, S ^a   De Stefanis, D ^a   Parola, M ^a   Bonelli, G ^a   Baccino, F M ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b Sezione di Patologia Generale   (Italy)

Author keywords

Apoptosis like death; Hepatoma; Iron chelation; Lysosomes; TNF

Indexed keywords

AMMONIUM CHLORIDE; ANTIOXIDANT; BAFILOMYCIN A1; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CATHEPSIN; CYCLOHEXIMIDE; DEFEROXAMINE MESYLATE; DIPHENYLIODONIUM SALT; IRON; IRON CHELATING AGENT; OXIDOREDUCTASE INHIBITOR; RECOMBINANT TUMOR NECROSIS FACTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ACIDITY; ANIMAL CELL; APOPTOSIS; ARTICLE; ATTENUATION; BIOCHEMISTRY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; HEPATOMA CELL; LYSOSOME; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT;

ACIDS; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASES; CATHEPSINS; CELL LINE, TUMOR; CYCLOHEXIMIDE; DEFEROXAMINE; ENZYME ACTIVATION; ENZYME INHIBITORS; INTRACELLULAR SPACE; IRON; LIVER NEOPLASMS, EXPERIMENTAL; LYSOSOMES; MITOCHONDRIA; RATS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 23944450157     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10495-005-2944-2     Document Type: Article

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