Cold-induced apoptosis of hepatocytes: Mitochondrial permeability transition triggered by nonmitochondrial chelatable iron

Free Radical Biology and Medicine

Volumn 35, Issue 12, 2003, Pages 1664-1678

  Rauen, Ursula ^a   Kerkweg, Uta ^a   Weisheit, Daniela ^b   Petrat, Frank ^a   Sustmann, Reiner ^b   De Groot, Herbert ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Chelatable iron; Free radicals; Hypothermia; Iron; Mitochondria; Mitochondrial iron chelator; Mitochondrial iron indicator; Mitochondrial membrane potential; Mitochondrial permeability transition; Organ preservation

Indexed keywords

2,2' BIPYRIDINE; DEFEROXAMINE MESYLATE; FRUCTOSE; IRON CHELATE; IRON CHELATING AGENT; RHODAMINE B [(1,10 PHENANTHROLIN 5 YL)AMINOCARBONYL]BENZYL ESTER; RHODAMINE B [(2,2' BIPYRIDIN 4 YL)AMINOCARBONYL]BENZYL ESTER; TRIFLUOPERAZINE; UNCLASSIFIED DRUG; UNIVERSITY OF WISCONSIN SOLUTION;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; COLD; COLD INJURY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; INCUBATION TIME; LIVER CELL; MALE; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0346995409     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2003.09.018     Document Type: Article

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