Transmissible spongiform encephalopathies: Assessment of exposure risk in the histological working environment using GC-MS detection of fatty acids as marker for central nervous tissues

International Journal of Hygiene and Environmental Health

Volumn 208, Issue 5, 2005, Pages 391-399

  Lücker, Ernst ^a   Biedermann, Wolfgang ^a   Lachhab, Sandra ^a   Heuss, Edgar ^b  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

BSE; Central nervous tissues; Exposure risk; Histology; TSE

Indexed keywords

2 HYDROXYTETRACOSANOIC ACID; BIOLOGICAL MARKER; FATTY ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; LIGNOCERIC ACID; NEURON SPECIFIC ENOLASE; OMEGA 7 TETRACOSENIC ACID; OMEGA 9 TETRACOSENIC ACID; UNCLASSIFIED DRUG;

ACCURACY; AIRBORNE INFECTION; ARTICLE; CENTRAL NERVOUS SYSTEM; DEHYDRATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FATTY ACID ANALYSIS; GAS CHROMATOGRAPHY; HISTOLOGY; HUMAN; IMMUNOCHEMISTRY; INTERMETHOD COMPARISON; MASS SPECTROMETRY; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; PRION DISEASE; PROTEIN ANALYSIS; RISK ASSESSMENT; TISSUE FIXATION; WESTERN BLOTTING;

EID: 23944447052     PISSN: 14384639     EISSN: 1618131X     Source Type: Journal    
DOI: 10.1016/j.ijheh.2005.05.003     Document Type: Article

References (34)

1. M.E. Agazzi, A. Bau, R. Barcarolo, E. Lücker, J. Barrero Moreno, and E. Anklam In-house validation of an improved sample extraction and clean-up method for GC determination of isomers of nervonic acid in meat products Anal. Bioanal. Chem. 376 2003 360 365
2. M.E. Agazzi, J. Barrero Moreno, C. von Holst, E. Lücker, and E. Anklam Quantitative analysis of tissue of the central nervous system in food products by GFAP-ELISA test kit. Results of an interlaboratory study Food Control 15 2004 297 301
3. Anonymous VDI 2265 - Feststellen der Staubsituation am Arbeitsplatz zur gewerbehygienischen Beurteilung 1980 VDI-Verlag Düsseldorf, Germany
4. Anonymous VDI 2463/ 7 - Messen von Partikeln. Messen der Massenkonzentration (Immission). Filterverfahren. Kleinfiltergerät GS 050 1982 VDI-Verlag Düsseldorf, Germany
5. Anonymous VDI 2463/ 8 - Messen von Partikeln. Messen der Massenkonzentration (Immission). Basisverfahren für den Vergleich von nichtfraktionierenden Verfahren 1982 VDI-Verlag Düsseldorf, Germany
6. Anonymous, 1998. Transmissible encephalopathy agents: safe working and prevention of infection. Advisory Committee on Dangerous Pathogens, Spongiform Encephalopathy Advisory Committee. The Statuatory Office, London. ISBN 0-11-322-166-5.
7. Anonymous, 1999. Opinion of the Scientific Steering Committee on the human exposure risk via food with respect to BSE. European Commission adopted on 10 December 1999.
8. R. Barcarolo, A. Bau, J. Barrero Moreno, J. Dimitrova, and E. Anklam On-line LC-GC method for determination of isomers of nervonic acid in meat-derived food J. Sep. Sci. 26 2003 1347 1352
9. W. Biedermann, E. Lücker, and A. Hensel Detection of tissues of the central nervous system (CNS) as specified risk material (SRM) in meat products by means of gas chromatography-mass spectrometry (GC-MS) Berl. Münch. Tierärztl. Wschr. 115 2002 131 134
10. W. Biedermann, E. Lücker, J. Pörschmann, S. Lachhab, U. Truyen, and A. Hensel Structural characterisation of some fatty acids from the brain as biomarkers of BSE risk material Anal. Bioanal. Chem. 379 2004 1031 1038
11. P. Brown, C.J. Gibbs Jr., H.L. Amyx, D.T. Kingsbury, R.G. Rohwer, M.P. Sulima, and D.C. Gajdusek Chemical disinfection of Creutzfeldt-Jakob disease virus N. Engl. J. Med. 306 1982 1279 1282
12. P. Brown, M. Preece, J.P. Brandel, T. Sato, L. McShane, I. Zerr, A. Fletcher, R.G. Will, M. Pocchiari, N.R. Cashman, J.H. d'Aignaux, L. Cervenakova, J. Fradkin, L.B. Schonberger, and S.J. Collins Iatrogenic Creutzfeldt-Jakob disease at the millennium Neurology 55 2000 1075 1081
13. B. Chesebro Introduction to the transmissible spongiform encephalopathies or prion diseases Br. Med. Bull. 66 2003 1 20
14. P.L. Cocco, A. Caperna, and F. Vinci Occupational risk factors for the sporadic form of Creutzfeldt-Jakob disease Med. Lav. 94 2003 353 363
15. D.C. Gajdusek, C.J. Gibbs, and M. Alpers Experimental transmission of a Kuru-like syndrome to chimpanzees Nature 209 1966 794 796
16. T. Garland, N. Bauer, and M. Bailey Brain emboli in the lungs of cattle after stunning Lancet 348 1996 610
17. E. Hughson, P. Reece, M.J. Dennis, and S. Oehlschlager Comparative evaluation of the performance of two commercial kits for the detection of central nervous system tissue in meat Food Addit. Contam. 20 2003 1034 1043
18. J.W. Ironside Neuropathological findings in new variant CJD and experimental transmission of BSE FEMS Immunol. Med. Microbiol. 21 1998 91 95
19. G. Legname, I.V. Baskakov, F.E. Cohen, S.J. DeArmond, and S.B. Prusiner Synthetic mammalian prions Science 305 2004 673 676
20. E. Lücker, E. Eigenbrodt, S. Wenisch, R. Leiser, and M. Bülte Development of an integrated procedure for the detection of central nervous tissue in meat products using cholesterol and neuron-specific enolase as markers J. Food Protect. 62 1999 268 276
21. E. Lücker, E. Eigenbrodt, S. Wenisch, R. Leiser, and M. Bülte Identification of central nervous system tissue in retail meat products J. Food Prot. 63 2000 258 263
22. E. Lücker, S. Horlacher, and E. Eigenbrodt Brain in human nutrition and variant Creutzfeldt-Jacob disease risk (vCJD): detection of brain in retail liver sausages using cholesterol and neuron specific enolase (NSE) as markers Br. J. Nutr. 86 2001 115 119
23. Lücker, E., Alter, T., Biedermann, W., Aupperle, H., Hardt, M., Schlottermüller, B., Lange, B., Barrero Moreno, J., Agazzi, M.E., Overhoff, M., Hensel, A., Anklam, E., Schoon, H.A., Groschup, M., 2002a. Nachweisverfahren von SRM in Fleischerzeugnissen: Möglichkeiten und Grenzen. In: Proceedings of DVG, 24-27 September 2002 Garmisch-Partenkirchen, ISBN 3-936815-59-3, 144-149.
24. E. Lücker, W. Biedermann, S. Lachhab, and A. Hensel Verfahren zum Nachweis von im Hinblick auf BSE unerwünschte Zutaten in Fleischerzeugnissen. 7. Nachweis von Hirngewebe mit der Gaschromatographie- Massenspektrometrie Fleischwirtschaft 82 2002 123 128
25. E. Lücker, W. Biedermann, S. Lachhab, U. Truyen, and A. Hensel GC-MS detection of central nervous tissues as TSE risk material in meat products: analytical quality Anal. Bioanal. Chem. 380 2004 866 870
26. M. Niederer, and R. Bollhalder Identification of species specific central nervous tissue by gas chromatography-mass spectrometry (GC-MS) - a possible method for supervision of meat products and cosmetics Mitt. Lebensm. Hyg. 92 2001 133 144
27. A. Noti, S. Biedermann-Brehm, M. Biedermann, and K. Grob Determination of central nervous and organ tissue in meat products through GC-MS analysis of marker fatty acids from sphingolipids and phospholipids Mitt. Lebensm. Hyg. 93 2002 387 401
28. D.M. Prendergast, J.J. Sheridan, D.J. Daly, D.A. McDowell, and I.S. Blair Dissemination of central nervous system tissue from the brain and spinal cord of cattle after captive bolt stunning and carcass splitting Meat Sci. 65 2003 1201 1209
29. M. Richard, A.G. Biacabe, A. Perret-Liaudet, L. McCardle, J.W. Ironside, and N. Kopp Protection of personnel and environment against Creutzfeldt-Jakob disease in pathology laboratories Clin. Exp. Pathol. 47 1999 192 200
30. G.R. Schmidt, K.L. Hossner, R.S. Yemm, D.H. Gould, and J.P. O'Callaghan An enzyme-linked immunosorbent assay for glial fibrillary acidic protein as an indicator of the presence of brain or spinal cord in meat J. Food Prot. 62 1999 394 397
31. J. Tateishi, M. Koga, Y. Sato, and R. Mori Properties of the transmissible agent derived from chronic spongiform encephalopathy Ann. Neurol. 7 1980 390 391
32. M.H.G. Tersteeg, P.A. Koolmees, and F. van Knapen Immunohistochemical detection of brain tissue in heated meat products Meat Sci. 61 2002 67 72
33. S. Wenisch, E. Lücker, E. Eigenbrodt, R. Leiser, and M. Bülte Detection of central nervous tissue in meat products - an immunohistological approach Nutr. Res. 19 1999 1165 1172
34. R.G. Will, J.W. Ironside, M. Zeidler, S.N. Cousens, K. Estibeiro, A. Alperovitch, S. Poser, M. Pocchiari, and A. Hoffmann A new variant of Creutzfeldt-Jakob disease in the UK Lancet 347 1996 921 925