메뉴 건너뛰기




Volumn 25, Issue 17, 2005, Pages 7399-7411

Molecular genetic analysis of the yeast repressor Rfx1/Crt1 reveals a novel two-step regulatory mechanism

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; HISTONE DEACETYLASE; PROTEIN CRT1; PROTEIN RFX1; PROTEIN SWI; RIBONUCLEOTIDE REDUCTASE; TRANSCRIPTION FACTOR IID; TRANSCRIPTION FACTOR SNF; TRANSCRIPTION FACTOR SSN6; TRANSCRIPTION FACTOR TUP1; UNCLASSIFIED DRUG;

EID: 23844531920     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.17.7399-7411.2005     Document Type: Article
Times cited : (34)

References (51)
  • 1
    • 0032826786 scopus 로고    scopus 로고
    • NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae
    • Basrai, M. A., V. E. Velculescu, K. W. Kinzler, and P. Hieter. 1999. NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae. Mol. Cell. Biol. 19:7041-7049.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7041-7049
    • Basrai, M.A.1    Velculescu, V.E.2    Kinzler, K.W.3    Hieter, P.4
  • 2
    • 0035910581 scopus 로고    scopus 로고
    • Recruitment of the yeast Tup1p-Ssn6p repressor is associated with localized decreases in histone acetylation
    • Bone, J. R., and S. Y. Roth. 2001. Recruitment of the yeast Tup1p-Ssn6p repressor is associated with localized decreases in histone acetylation. J. Biol. Chem. 276:1808-1813.
    • (2001) J. Biol. Chem. , vol.276 , pp. 1808-1813
    • Bone, J.R.1    Roth, S.Y.2
  • 3
    • 0029006193 scopus 로고
    • Positive control of yeast meiotic genes by the negative regulator UME6
    • Bowdish, K. S., H. E. Yuan, and A. P. Mitchell. 1995. Positive control of yeast meiotic genes by the negative regulator UME6. Mol. Cell. Biol. 15:2955-2961.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2955-2961
    • Bowdish, K.S.1    Yuan, H.E.2    Mitchell, A.P.3
  • 4
    • 0032579440 scopus 로고    scopus 로고
    • Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applications
    • Brachmann, C. B., A. Davies, G. J. Cost, E. Caputo, J. Li, P. Hieter, and J. D. Boeke. 1998. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14:115-132.
    • (1998) Yeast , vol.14 , pp. 115-132
    • Brachmann, C.B.1    Davies, A.2    Cost, G.J.3    Caputo, E.4    Li, J.5    Hieter, P.6    Boeke, J.D.7
  • 5
    • 0022328481 scopus 로고
    • A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor
    • Brent, R., and M. Ptashne. 1985. A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor. Cell 43:729-736.
    • (1985) Cell , vol.43 , pp. 729-736
    • Brent, R.1    Ptashne, M.2
  • 6
    • 0028264386 scopus 로고
    • The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure
    • Cooper, J. P., S. Y. Roth, and R. T. Simpson. 1994. The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure. Genes Dev. 8:1400-1410.
    • (1994) Genes Dev. , vol.8 , pp. 1400-1410
    • Cooper, J.P.1    Roth, S.Y.2    Simpson, R.T.3
  • 7
    • 0036142163 scopus 로고    scopus 로고
    • Histone-dependent association of Tup1-Ssn6 with repressed genes in vivo
    • Davie, J. K., R. J. Trumbly, and S. Y. R. Dent. 2002. Histone-dependent association of Tup1-Ssn6 with repressed genes in vivo. Mol. Cell. Biol. 22:693-703.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 693-703
    • Davie, J.K.1    Trumbly, R.J.2    Dent, S.Y.R.3
  • 8
    • 0348010365 scopus 로고    scopus 로고
    • Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo
    • Davie, J. K., D. G. Edmondson, C. B. Coco, and S. Y. Dent. 2003. Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo. J. Biol. Chem. 278:50158-50162.
    • (2003) J. Biol. Chem. , vol.278 , pp. 50158-50162
    • Davie, J.K.1    Edmondson, D.G.2    Coco, C.B.3    Dent, S.Y.4
  • 9
    • 0034142029 scopus 로고    scopus 로고
    • The organized chromatin domain of the repressed yeast a-specific gene STE6 contains two molecules of the corepressor Tup1p per nucleosome
    • Ducker, C. E., and R. T. Simpson. 2000. The organized chromatin domain of the repressed yeast a-specific gene STE6 contains two molecules of the corepressor Tup1p per nucleosome. EMBO J. 19:400-409.
    • (2000) EMBO J. , vol.19 , pp. 400-409
    • Ducker, C.E.1    Simpson, R.T.2
  • 10
    • 0030003051 scopus 로고    scopus 로고
    • Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4
    • Edmondson, D. G., M. M. Smith, and S. Y. Roth. 1996. Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4. Genes Dev. 10:1247-1259.
    • (1996) Genes Dev. , vol.10 , pp. 1247-1259
    • Edmondson, D.G.1    Smith, M.M.2    Roth, S.Y.3
  • 11
    • 0027605113 scopus 로고
    • DNA damage and cell cycle regulation of ribonucleotide reductase
    • Elledge, S. J., Z. Zhou, J. B. Allen, and T. A. Navas. 1993. DNA damage and cell cycle regulation of ribonucleotide reductase. Bioessays 15:333-339.
    • (1993) Bioessays , vol.15 , pp. 333-339
    • Elledge, S.J.1    Zhou, Z.2    Allen, J.B.3    Navas, T.A.4
  • 12
    • 0029997190 scopus 로고    scopus 로고
    • RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom
    • Emery, P., B. Durand, B. Mach, and W. Reith. 1996. RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom. Nucleic Acids Res. 24:803-807.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 803-807
    • Emery, P.1    Durand, B.2    Mach, B.3    Reith, W.4
  • 15
    • 0034332501 scopus 로고    scopus 로고
    • Tup1p represses Mcm1p transcriptional activation and chromatin remodeling of an a-cell-specific gene
    • Gavin, I. M., M. P. Kladde, and R. T. Simpson. 2000. Tup1p represses Mcm1p transcriptional activation and chromatin remodeling of an a-cell-specific gene. EMBO J. 19:5875-5883.
    • (2000) EMBO J. , vol.19 , pp. 5875-5883
    • Gavin, I.M.1    Kladde, M.P.2    Simpson, R.T.3
  • 16
    • 0034650893 scopus 로고    scopus 로고
    • The coregulator exchange in transcriptional functions of nuclear receptors
    • Glass, C. K., and M. G. Rosenfeld. 2000. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 14:121-141.
    • (2000) Genes Dev. , vol.14 , pp. 121-141
    • Glass, C.K.1    Rosenfeld, M.G.2
  • 17
    • 0034672065 scopus 로고    scopus 로고
    • Srb7p is a physical and physiological target of Tup1p
    • Gromöller, A., and N. Lehming. 2000. Srb7p is a physical and physiological target of Tup1p. EMBO J. 19:6845-6852.
    • (2000) EMBO J. , vol.19 , pp. 6845-6852
    • Gromöller, A.1    Lehming, N.2
  • 18
    • 0033064319 scopus 로고    scopus 로고
    • Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction
    • Hecht, A., and M. Grunstein. 1999. Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction. Methods Enzymol. 304:399-414.
    • (1999) Methods Enzymol. , vol.304 , pp. 399-414
    • Hecht, A.1    Grunstein, M.2
  • 19
    • 0028131434 scopus 로고
    • Transcriptional repression directed by the yeast α2 protein in vitro
    • Herschbach, B. M., M. B. Arnaud, and A. D. Johnson. 1994. Transcriptional repression directed by the yeast α2 protein in vitro. Nature 370:309-311.
    • (1994) Nature , vol.370 , pp. 309-311
    • Herschbach, B.M.1    Arnaud, M.B.2    Johnson, A.D.3
  • 20
    • 0032483576 scopus 로고    scopus 로고
    • The DNA replication and damage check point pathways induce transcription by inhibiting the Crt1 repressor
    • Huang, M., Z. Zhou, and S. J. Elledge. 1998. The DNA replication and damage check point pathways induce transcription by inhibiting the Crt1 repressor. Cell 94:595-605.
    • (1998) Cell , vol.94 , pp. 595-605
    • Huang, M.1    Zhou, Z.2    Elledge, S.J.3
  • 21
    • 0033049420 scopus 로고    scopus 로고
    • Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains
    • Iwama, A., J. Pan, P. Zhang, W. Reith, B. Mach, D. G. Tenen, and Z. Sun. 1999. Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains. Mol. Cell. Biol. 19:3940-3950.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3940-3950
    • Iwama, A.1    Pan, J.2    Zhang, P.3    Reith, W.4    Mach, B.5    Tenen, D.G.6    Sun, Z.7
  • 22
    • 0033585025 scopus 로고    scopus 로고
    • The dimerization/repression domain of RFX1 is related to a conserved region of its yeast homologues Crt1 and Sak1: A new function for an ancient motif
    • Katan-Khaykovich, Y., I. Spiegel, and Y. Shaul. 1999. The dimerization/repression domain of RFX1 is related to a conserved region of its yeast homologues Crt1 and Sak1: a new function for an ancient motif. J. Mol. Biol. 294:121-137.
    • (1999) J. Mol. Biol. , vol.294 , pp. 121-137
    • Katan-Khaykovich, Y.1    Spiegel, I.2    Shaul, Y.3
  • 23
    • 0342757661 scopus 로고    scopus 로고
    • Derepression of DNA damage-regulated genes requires yeast TAF(II)s
    • Li, B., and J. C. Reese. 2000. Derepression of DNA damage-regulated genes requires yeast TAF(II)s. EMBO J. 19:4091-4100.
    • (2000) EMBO J. , vol.19 , pp. 4091-4100
    • Li, B.1    Reese, J.C.2
  • 24
    • 0035823553 scopus 로고    scopus 로고
    • Ssn6-Tup1 regulates RNR3 by positioning nucleosomes and affecting the chromatin structure at the upstream repression sequence
    • Li, B., and J. C. Reese. 2001. Ssn6-Tup1 regulates RNR3 by positioning nucleosomes and affecting the chromatin structure at the upstream repression sequence. J. Biol. Chem. 276:33788-33797.
    • (2001) J. Biol. Chem. , vol.276 , pp. 33788-33797
    • Li, B.1    Reese, J.C.2
  • 25
    • 0031820288 scopus 로고    scopus 로고
    • Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
    • Longtine, M. S., A. McKenzie III, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953-961.
    • (1998) Yeast , vol.14 , pp. 953-961
    • Longtine, M.S.1    McKenzie III, A.2    Demarini, D.J.3    Shah, N.G.4    Wach, A.5    Brachat, A.6    Philippsen, P.7    Pringle, J.R.8
  • 26
    • 1942502820 scopus 로고    scopus 로고
    • Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling
    • Nagaich, A. K., D. A. Walker, R. Wolford, and G. L. Hager. 2004. Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling. Mol. Cell 14:163-174.
    • (2004) Mol. Cell , vol.14 , pp. 163-174
    • Nagaich, A.K.1    Walker, D.A.2    Wolford, R.3    Hager, G.L.4
  • 28
    • 0036298418 scopus 로고    scopus 로고
    • Cti1, a PHD domain protein, bridges the Cyc8-Tup1 corepressor and the SAGA coactivator to overcome repression at GAL1
    • Papamichos-Chronakis, M., T. Petrakis, E. Ktistaki, I. Topalido, and D. Tzamarias. 2002. Cti1, a PHD domain protein, bridges the Cyc8-Tup1 corepressor and the SAGA coactivator to overcome repression at GAL1. Mol. Cell 9:1297-1305.
    • (2002) Mol. Cell , vol.9 , pp. 1297-1305
    • Papamichos-Chronakis, M.1    Petrakis, T.2    Ktistaki, E.3    Topalido, I.4    Tzamarias, D.5
  • 29
    • 0036289351 scopus 로고    scopus 로고
    • Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress
    • Proft, M., and K. Struhl. 2002. Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress. Mol. Cell 9:1307-1317.
    • (2002) Mol. Cell , vol.9 , pp. 1307-1317
    • Proft, M.1    Struhl, K.2
  • 30
    • 0028169339 scopus 로고
    • Yeast TAFIIs in a multisubunit complex required for activated transcription
    • Reese, J. C., L. Apone, S. S. Walker, L. A. Griffin, and M. R. Green. 1994. Yeast TAFIIs in a multisubunit complex required for activated transcription. Nature 371:523-527.
    • (1994) Nature , vol.371 , pp. 523-527
    • Reese, J.C.1    Apone, L.2    Walker, S.S.3    Griffin, L.A.4    Green, M.R.5
  • 31
    • 0025790171 scopus 로고
    • In vivo footprinting of rat TAT gene: Dynamic interplay between the glucocorticoid receptor and a liver-specific factor
    • Rigaud, G., J. Roux, R. Pictet, and T. Grange. 1991. In vivo footprinting of rat TAT gene: dynamic interplay between the glucocorticoid receptor and a liver-specific factor. Cell 67:977-986.
    • (1991) Cell , vol.67 , pp. 977-986
    • Rigaud, G.1    Roux, J.2    Pictet, R.3    Grange, T.4
  • 33
    • 0028906077 scopus 로고
    • Chromatin-mediated transcriptional repression in yeast
    • Roth, S. Y. 1995. Chromatin-mediated transcriptional repression in yeast. Curr. Opin. Genet. Dev. 5:168-173.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 168-173
    • Roth, S.Y.1
  • 34
    • 0029990949 scopus 로고    scopus 로고
    • Induction of meiosis in Saccharomyces cerevisiae depends on conversion of the transcriptional repressor Ume6 to a positive regulator by its regulated association with the transcriptional activator Ime1
    • Rubin-Bejerano, I., S. Mandel, K. Robzyk, and Y. Kassir. 1996. Induction of meiosis in Saccharomyces cerevisiae depends on conversion of the transcriptional repressor Ume6 to a positive regulator by its regulated association with the transcriptional activator Ime1. Mol. Cell. Biol. 16:2518-2526.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2518-2526
    • Rubin-Bejerano, I.1    Mandel, S.2    Robzyk, K.3    Kassir, Y.4
  • 36
    • 0037067727 scopus 로고    scopus 로고
    • The RFX family interacts at the collagen (COL1A2) start site and represses transcription
    • Sengupta, P. K., J. Fargo, and B. D. Smith. 2002. The RFX family interacts at the collagen (COL1A2) start site and represses transcription. J. Biol. Chem. 277:24926-24937.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24926-24937
    • Sengupta, P.K.1    Fargo, J.2    Smith, B.D.3
  • 37
    • 0037442819 scopus 로고    scopus 로고
    • SWI/SNF-dependent chromatin remodeling of RNR3 requires TAF(II)s and the general transcription machinery
    • Sharma, V. M., B. Li, and J. C. Reese. 2003. SWI/SNF-dependent chromatin remodeling of RNR3 requires TAF(II)s and the general transcription machinery. Genes Dev. 17:502-515.
    • (2003) Genes Dev. , vol.17 , pp. 502-515
    • Sharma, V.M.1    Li, B.2    Reese, J.C.3
  • 38
    • 0034234638 scopus 로고    scopus 로고
    • Turning genes off by Ssn6-Tup1: A conserved system of transcriptional repression in eukaryotes
    • Smith, R. L., and A. D. Johnson. 2000. Turning genes off by Ssn6-Tup1: a conserved system of transcriptional repression in eukaryotes. Trends Biochem. Sci. 25:325-330.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 325-330
    • Smith, R.L.1    Johnson, A.D.2
  • 39
    • 0034839973 scopus 로고    scopus 로고
    • Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin
    • Suka, N., Y. Suka, A. A. Carmen, J. Wu, and M. Grunstein. 2001. Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin. Mol. Cell 8:473-479.
    • (2001) Mol. Cell , vol.8 , pp. 473-479
    • Suka, N.1    Suka, Y.2    Carmen, A.A.3    Wu, J.4    Grunstein, M.5
  • 40
    • 0031835267 scopus 로고    scopus 로고
    • Co-activators and corepressors in the integration of transcriptional responses
    • Torchia, J., C. Glass, and M. G. Rosenfeld. 1998. Co-activators and corepressors in the integration of transcriptional responses. Curr. Opin. Cell Biol. 10:373-383.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 373-383
    • Torchia, J.1    Glass, C.2    Rosenfeld, M.G.3
  • 41
    • 0024256134 scopus 로고
    • Cloning and characterization of the CYC8 gene mediating glucose repression in yeast
    • Trumbly, R. J. 1988. Cloning and characterization of the CYC8 gene mediating glucose repression in yeast. Gene 73:97-111.
    • (1988) Gene , vol.73 , pp. 97-111
    • Trumbly, R.J.1
  • 42
    • 0029787072 scopus 로고    scopus 로고
    • Transcription activation in cells lacking TAFIIs
    • Walker, S. S., J. C. Reese, L. M. Apone, and M. R. Green. 1996. Transcription activation in cells lacking TAFIIs. Nature 383:185-188.
    • (1996) Nature , vol.383 , pp. 185-188
    • Walker, S.S.1    Reese, J.C.2    Apone, L.M.3    Green, M.R.4
  • 43
    • 0034996711 scopus 로고    scopus 로고
    • Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast
    • Washburn, B. K., and R. E. Esposito. 2001. Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast. Mol. Cell. Biol. 21:2057-2069.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 2057-2069
    • Washburn, B.K.1    Esposito, R.E.2
  • 45
    • 0030752309 scopus 로고    scopus 로고
    • Cell type-specific chromatin organization of the region that governs directionality of yeast mating type switching
    • Weiss, K., and R. T. Simpson. 1997. Cell type-specific chromatin organization of the region that governs directionality of yeast mating type switching. EMBO J. 16:4352-4360.
    • (1997) EMBO J. , vol.16 , pp. 4352-4360
    • Weiss, K.1    Simpson, R.T.2
  • 46
    • 0025220996 scopus 로고
    • Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae
    • Williams, F. E., and R. J. Trumbly. 1990. Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae. Mol. Cell. Biol. 10:6500-6511.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6500-6511
    • Williams, F.E.1    Trumbly, R.J.2
  • 47
    • 0035105035 scopus 로고    scopus 로고
    • TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast
    • Wu, J., N. Suka, M. Carlson, and M. Grunstein. 2001. TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast. Mol. Cell 7:117-126.
    • (2001) Mol. Cell , vol.7 , pp. 117-126
    • Wu, J.1    Suka, N.2    Carlson, M.3    Grunstein, M.4
  • 48
    • 3042551856 scopus 로고    scopus 로고
    • Ssn6-Tup1 requires the ISW2 complex to position nucleosomes in Saccharomyces cerevisiae
    • Zhang, Z., and J. C. Reese. 2004. Ssn6-Tup1 requires the ISW2 complex to position nucleosomes in Saccharomyces cerevisiae. EMBO J. 23:2246-2257.
    • (2004) EMBO J. , vol.23 , pp. 2246-2257
    • Zhang, Z.1    Reese, J.C.2
  • 49
    • 4544308621 scopus 로고    scopus 로고
    • Redundant mechanisms are used by Ssn6-Tup1 in repressing chromosomal gene transcription in Saccharomyces cerevisiae
    • Zhang, Z., and J. C. Reese. 2004. Redundant mechanisms are used by Ssn6-Tup1 in repressing chromosomal gene transcription in Saccharomyces cerevisiae. J. Biol. Chem. 279:39240-39250.
    • (2004) J. Biol. Chem. , vol.279 , pp. 39240-39250
    • Zhang, Z.1    Reese, J.C.2
  • 50
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou, B. B., and S. J. Elledge. 2000. The DNA damage response: putting checkpoints in perspective. Nature 408:433-439.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2
  • 51
    • 0026651652 scopus 로고
    • Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae
    • Zhou, Z., and S. J. Elledge. 1992. Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae. Genetics 131:851-866.
    • (1992) Genetics , vol.131 , pp. 851-866
    • Zhou, Z.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.