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Volumn 294, Issue 1, 1999, Pages 121-137

The dimerization/repression domain of RFX1 is related to a conserved region of its yeast homologues Crt1 and Sak1: A new function for an ancient motif

Author keywords

Dimerization; EMSA; Molecular evolution; RFX family; Transcriptional repression

Indexed keywords

DNA BINDING PROTEIN; TRANSCRIPTION FACTOR;

EID: 0033585025     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3245     Document Type: Article
Times cited : (16)

References (49)
  • 1
    • 0032499222 scopus 로고    scopus 로고
    • The kinase activity of c-Abl but not v-Abl is potentiated by direct interaction with RFX1, a protein that binds the enhancers of several viruses and cell-cycle regulated genes
    • Agami R., Shaul Y. The kinase activity of c-Abl but not v-Abl is potentiated by direct interaction with RFX1, a protein that binds the enhancers of several viruses and cell-cycle regulated genes. Oncogene. 16:1998;1779-1788.
    • (1998) Oncogene , vol.16 , pp. 1779-1788
    • Agami, R.1    Shaul, Y.2
  • 2
    • 0027537576 scopus 로고
    • Interactions of coiled coils in transcription factors: Where is the specificity?
    • Baxevanis A. D., Vinson C. R. Interactions of coiled coils in transcription factors: where is the specificity? Curr. Opin. Genet. Dev. 3:1993;278-285.
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 278-285
    • Baxevanis, A.D.1    Vinson, C.R.2
  • 3
    • 0024501948 scopus 로고
    • Cellular factors that interact with the hepatitis B virus enhancer
    • Ben-Levy R., Faktor O., Berger I., Shaul Y. Cellular factors that interact with the hepatitis B virus enhancer. Mol. Cell Biol. 9:1989;1804-1809.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 1804-1809
    • Ben-Levy, R.1    Faktor, O.2    Berger, I.3    Shaul, Y.4
  • 4
    • 0029815221 scopus 로고    scopus 로고
    • Interactions of the transcription factors MIBP1 and RFX1 with the EP element of the hepatitis B virus enhancer
    • Blake M., Niklinski J., Zajac-Kaye M. Interactions of the transcription factors MIBP1 and RFX1 with the EP element of the hepatitis B virus enhancer. J. Virol. 70:1996;6060-6066.
    • (1996) J. Virol. , vol.70 , pp. 6060-6066
    • Blake, M.1    Niklinski, J.2    Zajac-Kaye, M.3
  • 5
    • 0025977776 scopus 로고
    • Interaction of nuclear factor EF-1A with the polyomavirus enhancer region
    • Bolwig G. M., Hearing P. Interaction of nuclear factor EF-1A with the polyomavirus enhancer region. J. Virol. 65:1991;1884-1892.
    • (1991) J. Virol. , vol.65 , pp. 1884-1892
    • Bolwig, G.M.1    Hearing, P.2
  • 6
    • 0031579248 scopus 로고    scopus 로고
    • Interaction of transcription factors RFX1 and MIBP1 with the gamma motif of the negative regulatory element of the hepatitis B virus core promoter
    • Buckwold V. E., Chen M., Ou J.-H. Interaction of transcription factors RFX1 and MIBP1 with the gamma motif of the negative regulatory element of the hepatitis B virus core promoter. Virology. 227:1997;515-518.
    • (1997) Virology , vol.227 , pp. 515-518
    • Buckwold, V.E.1    Chen, M.2    Ou, J.-H.3
  • 7
    • 0026725943 scopus 로고
    • Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor
    • Burbach K. M., Poland A., Bradfield C. A. Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proc. Natl Acad. Sci. USA. 89:1992;8185-8189.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 8185-8189
    • Burbach, K.M.1    Poland, A.2    Bradfield, C.A.3
  • 8
    • 0028905281 scopus 로고
    • Interaction of EF-C/RFX-1 with the inverted repeat of viral enhancer regions is required for transactivation
    • David E., Garcia A. D., Hearing P. Interaction of EF-C/RFX-1 with the inverted repeat of viral enhancer regions is required for transactivation. J. Biol. Chem. 270:1995;8353-8360.
    • (1995) J. Biol. Chem. , vol.270 , pp. 8353-8360
    • David, E.1    Garcia, A.D.2    Hearing, P.3
  • 9
    • 0025454837 scopus 로고
    • Functional organization of the hepatitis B virus enhancer
    • Dikstein R., Faktor O., Ben-Levy R., Shaul Y. Functional organization of the hepatitis B virus enhancer. Mol. Cell Biol. 10:1990;3682-3689.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 3682-3689
    • Dikstein, R.1    Faktor, O.2    Ben-Levy, R.3    Shaul, Y.4
  • 10
    • 0026642895 scopus 로고
    • C-abl has a sequence-specific enhancer binding activity
    • Dikstein R., Heffetz D., Ben-Neriah Y., Shaul Y. c-abl has a sequence-specific enhancer binding activity. Cell. 69:1992;751-757.
    • (1992) Cell , vol.69 , pp. 751-757
    • Dikstein, R.1    Heffetz, D.2    Ben-Neriah, Y.3    Shaul, Y.4
  • 11
    • 0030006307 scopus 로고    scopus 로고
    • P140/c-Abl that binds DNA is preferentially phosphorylated at tyrosine residues
    • Dikstein R., Agami R., Heffetz D., Shaul Y. p140/c-Abl that binds DNA is preferentially phosphorylated at tyrosine residues. Proc. Natl Acad. Sci. USA. 93:1996;2387-2391.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 2387-2391
    • Dikstein, R.1    Agami, R.2    Heffetz, D.3    Shaul, Y.4
  • 12
    • 0029997190 scopus 로고    scopus 로고
    • RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom
    • Emery P., Durand B., Mach B., Reith W. RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom. Nucl. Acids Res. 24:1996a;803-807.
    • (1996) Nucl. Acids Res. , vol.24 , pp. 803-807
    • Emery, P.1    Durand, B.2    Mach, B.3    Reith, W.4
  • 13
    • 0029982706 scopus 로고    scopus 로고
    • A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity
    • Emery P., Strubin M., Hofmann K., Bucher P., Mach B., Reith W. A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity. Mol. Cell Biol. 16:1996b;4486-4494.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 4486-4494
    • Emery, P.1    Strubin, M.2    Hofmann, K.3    Bucher, P.4    Mach, B.5    Reith, W.6
  • 14
    • 0025329841 scopus 로고
    • Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor
    • Fawell S. E., Lees J. A., White R., Parker M. G. Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor. Cell. 60:1990;953-962.
    • (1990) Cell , vol.60 , pp. 953-962
    • Fawell, S.E.1    Lees, J.A.2    White, R.3    Parker, M.G.4
  • 15
    • 0032908351 scopus 로고    scopus 로고
    • Characterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factor
    • Greschik H., Wurtz J.-M., Hublitz P., Kohler F., Moras D., Schule R. Characterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factor. Mol. Cell Biol. 19:1999;690-703.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 690-703
    • Greschik, H.1    Wurtz, J.-M.2    Hublitz, P.3    Kohler, F.4    Moras, D.5    Schule, R.6
  • 16
    • 0026665461 scopus 로고
    • The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters
    • Herrero-Sanchez C., Reith W., Silacci P., Mach B. The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters. Mol. Cell Biol. 12:1992;4076-4083.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 4076-4083
    • Herrero-Sanchez, C.1    Reith, W.2    Silacci, P.3    Mach, B.4
  • 17
    • 0032483576 scopus 로고    scopus 로고
    • The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor
    • Huang M., Zhou Z., Elledge S. J. The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor. Cell. 94:1998;595-605.
    • (1998) Cell , vol.94 , pp. 595-605
    • Huang, M.1    Zhou, Z.2    Elledge, S.J.3
  • 18
    • 0033049420 scopus 로고    scopus 로고
    • Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains
    • Iwama A., Pan J., Zhang P., Reith W., Mach B., Tenen D. G., Sun Z. Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains. Mol. Cell Biol. 19:1999;3940-3950.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 3940-3950
    • Iwama, A.1    Pan, J.2    Zhang, P.3    Reith, W.4    Mach, B.5    Tenen, D.G.6    Sun, Z.7
  • 19
    • 0025253013 scopus 로고
    • Transcriptional regulation by dimerization: Two sides to an incestuous relationship
    • Jones N. Transcriptional regulation by dimerization: two sides to an incestuous relationship. Cell. 61:1990;9-11.
    • (1990) Cell , vol.61 , pp. 9-11
    • Jones, N.1
  • 20
    • 0030843563 scopus 로고    scopus 로고
    • The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities
    • Katan Y., Agami R., Shaul Y. The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities. Nucl. Acids Res. 25:1997;3621-3628.
    • (1997) Nucl. Acids Res. , vol.25 , pp. 3621-3628
    • Katan, Y.1    Agami, R.2    Shaul, Y.3
  • 21
    • 0032544427 scopus 로고    scopus 로고
    • RFX1, a single DNA-binding protein with a split dimerization domain, generates alternative complexes
    • Katan-Khaykovich Y., Shaul Y. RFX1, a single DNA-binding protein with a split dimerization domain, generates alternative complexes. J. Biol. Chem. 273:1998;24504-24512.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24504-24512
    • Katan-Khaykovich, Y.1    Shaul, Y.2
  • 23
    • 0029100665 scopus 로고
    • Transcription factors RFX1/EF-C and ATF-1 associate with the adenovirus E1A- responsive element of the human proliferating cell nuclear antigen promoter
    • Labrie C., Lee B. H., Mathews M. B. Transcription factors RFX1/EF-C and ATF-1 associate with the adenovirus E1A- responsive element of the human proliferating cell nuclear antigen promoter. Nucl. Acids Res. 23:1995;3732-3741.
    • (1995) Nucl. Acids Res. , vol.23 , pp. 3732-3741
    • Labrie, C.1    Lee, B.H.2    Mathews, M.B.3
  • 24
    • 0031906224 scopus 로고    scopus 로고
    • Regulation of the human proliferating cell nuclear antigen promoter by the adenovirus E1A-associated protein p107
    • Lee B. H., Liu M., Mathews M. B. Regulation of the human proliferating cell nuclear antigen promoter by the adenovirus E1A-associated protein p107. J. Virol. 72:1998;1138-1145.
    • (1998) J. Virol. , vol.72 , pp. 1138-1145
    • Lee, B.H.1    Liu, M.2    Mathews, M.B.3
  • 25
    • 0033024025 scopus 로고    scopus 로고
    • Involvement of RFX1 protein in the regulation of the human proliferating cell nuclear antigen promoter
    • Liu M., Lee B. H., Mathews M. B. Involvement of RFX1 protein in the regulation of the human proliferating cell nuclear antigen promoter. J. Biol. Chem. 274:1999;15433-15439.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15433-15439
    • Liu, M.1    Lee, B.H.2    Mathews, M.B.3
  • 26
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf D. J., Evans R. M. The RXR heterodimers and orphan receptors. Cell. 83:1995;841-850.
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 28
    • 0031833450 scopus 로고    scopus 로고
    • The nuclear receptor ligand-binding domain: Structure and function
    • Moras D., Gronemeyer H. The nuclear receptor ligand-binding domain: structure and function. Curr. Opin. Cell Biol. 10:1998;384-391.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 384-391
    • Moras, D.1    Gronemeyer, H.2
  • 29
    • 0032518913 scopus 로고    scopus 로고
    • P53 binds and represses the HBV enhancer: An adjacent enhancer element can reverse the transcription effect of p53
    • Ori A., Zauberman A., Doitsh G., Paran N., Oren M., Shaul Y. p53 binds and represses the HBV enhancer: an adjacent enhancer element can reverse the transcription effect of p53. EMBO J. 17:1998;544-553.
    • (1998) EMBO J. , vol.17 , pp. 544-553
    • Ori, A.1    Zauberman, A.2    Doitsh, G.3    Paran, N.4    Oren, M.5    Shaul, Y.6
  • 31
    • 0024397338 scopus 로고
    • Binding of nuclear factor EF-C to a functional domain of the hepatitis B virus enhancer region
    • Ostapchuk P., Scheirle G., Hearing P. Binding of nuclear factor EF-C to a functional domain of the hepatitis B virus enhancer region. Mol. Cell Biol. 9:1989;2787-2797.
    • (1989) Mol. Cell Biol. , vol.9 , pp. 2787-2797
    • Ostapchuk, P.1    Scheirle, G.2    Hearing, P.3
  • 32
    • 0029736983 scopus 로고    scopus 로고
    • Two distinct dimerization interfaces differentially modulate target gene specificity of nuclear hormone receptors
    • Perlmann T., Umesono K., Rangarajan P. N., Forman B. M., Evans R. M. Two distinct dimerization interfaces differentially modulate target gene specificity of nuclear hormone receptors. Mol. Endocrinol. 10:1996;958-966.
    • (1996) Mol. Endocrinol. , vol.10 , pp. 958-966
    • Perlmann, T.1    Umesono, K.2    Rangarajan, P.N.3    Forman, B.M.4    Evans, R.M.5
  • 33
    • 0029005330 scopus 로고
    • The myc intron-binding polypeptide associates with RFX1 in vivo and binds to the major histocompatibility complex class II promoter region, to the hepatitis B virus enhancer, and to regulatory regions of several distinct viral genes
    • Reinhold W., Emens L., Itkes A., Blake M., Ichinose I., Zajac-Kaye M. The myc intron-binding polypeptide associates with RFX1 in vivo and binds to the major histocompatibility complex class II promoter region, to the hepatitis B virus enhancer, and to regulatory regions of several distinct viral genes. Mol. Cell Biol. 15:1995;3041-3048.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3041-3048
    • Reinhold, W.1    Emens, L.2    Itkes, A.3    Blake, M.4    Ichinose, I.5    Zajac-Kaye, M.6
  • 34
    • 0346225767 scopus 로고
    • Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation
    • Reith W., Barras E., Satola S., Kobr M., Reinhart D., Herrero-Sanchez C., Mach B. Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation. Proc. Natl Acad. Sci. USA. 86:1989;4200-4204.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 4200-4204
    • Reith, W.1    Barras, E.2    Satola, S.3    Kobr, M.4    Reinhart, D.5    Herrero-Sanchez, C.6    Mach, B.7
  • 35
    • 0025108425 scopus 로고
    • MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain
    • Reith W., Herrero-Sanchez C., Kobr M., Silacci P., Berte C., Barras E., Fey S., Mach B. MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain. Genes Dev. 4:1990;1528-1540.
    • (1990) Genes Dev. , vol.4 , pp. 1528-1540
    • Reith, W.1    Herrero-Sanchez, C.2    Kobr, M.3    Silacci, P.4    Berte, C.5    Barras, E.6    Fey, S.7    Mach, B.8
  • 36
    • 0028057841 scopus 로고
    • RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins
    • Reith W., Ucla C., Barras E., Gaud A., Durand B., Herrero-Sanchez C., Kobr M., Mach B. RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins. Mol. Cell Biol. 14:1994;1230-1244.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 1230-1244
    • Reith, W.1    Ucla, C.2    Barras, E.3    Gaud, A.4    Durand, B.5    Herrero-Sanchez, C.6    Kobr, M.7    Mach, B.8
  • 37
    • 0027489815 scopus 로고
    • Transcription factor RFX1 helps control the promoter of the mouse ribosomal protein-encoding gene rpL30 by binding to its alpha element
    • Safrany G., Perry R. P. Transcription factor RFX1 helps control the promoter of the mouse ribosomal protein-encoding gene rpL30 by binding to its alpha element. Gene. 132:1993;279-283.
    • (1993) Gene , vol.132 , pp. 279-283
    • Safrany, G.1    Perry, R.P.2
  • 38
    • 0029005931 scopus 로고
    • The relative contributions of various transcription factors to the overall promoter strength of the mouse ribosomal protein L30 gene
    • Safrany G., Perry R. P. The relative contributions of various transcription factors to the overall promoter strength of the mouse ribosomal protein L30 gene. Eur. J. Biochem. 230:1995;1066-1072.
    • (1995) Eur. J. Biochem. , vol.230 , pp. 1066-1072
    • Safrany, G.1    Perry, R.P.2
  • 39
    • 0029938795 scopus 로고    scopus 로고
    • Activation and repression by nuclear hormone receptors: Hormone modulates an equilibrium between active and repressive states
    • Schulman I. G., Juguilon H., Evans R. M. Activation and repression by nuclear hormone receptors: hormone modulates an equilibrium between active and repressive states. Mol. Cell Biol. 16:1996;3807-3813.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 3807-3813
    • Schulman, I.G.1    Juguilon, H.2    Evans, R.M.3
  • 40
    • 0027437250 scopus 로고
    • Antisense oligonucleotides specific for regulatory factor RFX-1 inhibit inducible but not constitutive expression of all major histocompatibility complex class II genes
    • Siegrist C. A., Mach B. Antisense oligonucleotides specific for regulatory factor RFX-1 inhibit inducible but not constitutive expression of all major histocompatibility complex class II genes. Eur. J. Immunol. 23:1993;2903-2908.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2903-2908
    • Siegrist, C.A.1    Mach, B.2
  • 41
    • 0027386090 scopus 로고
    • RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer
    • Siegrist C. A., Durand B., Emery P., David E., Hearing P., Mach B., Reith W. RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer. Mol. Cell Biol. 13:1993;6375-6384.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 6375-6384
    • Siegrist, C.A.1    Durand, B.2    Emery, P.3    David, E.4    Hearing, P.5    Mach, B.6    Reith, W.7
  • 42
    • 11944266638 scopus 로고
    • A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)
    • Steimle V., Durand B., Barras E., Zufferey M., Hadam M. R., Mach B., Reith W. A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome). Genes Dev. 9:1995;1021-1032.
    • (1995) Genes Dev. , vol.9 , pp. 1021-1032
    • Steimle, V.1    Durand, B.2    Barras, E.3    Zufferey, M.4    Hadam, M.R.5    Mach, B.6    Reith, W.7
  • 43
    • 0024204095 scopus 로고
    • B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene
    • Tsang S. Y., Nakanishi M., Peterlin B. M. B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene. Proc. Natl Acad. Sci. USA. 85:1988;8598-8602.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 8598-8602
    • Tsang, S.Y.1    Nakanishi, M.2    Peterlin, B.M.3
  • 44
    • 0025120331 scopus 로고
    • Mutational analysis of the DRA promoter: Cis-acting sequences and trans-acting factors
    • Tsang S. Y., Nakanishi M., Peterlin B. M. Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors. Mol. Cell Biol. 10:1990;711-709.
    • (1990) Mol. Cell Biol. , vol.10 , pp. 711-709
    • Tsang, S.Y.1    Nakanishi, M.2    Peterlin, B.M.3
  • 45
  • 46
    • 0024246141 scopus 로고
    • Multiple negative elements upstream of the murine c-myc gene share nuclear factor binding sites with SV40 and polyoma enhancers
    • Weisinger G., Remmers E. F., Hearing P., Marcu K. B. Multiple negative elements upstream of the murine c-myc gene share nuclear factor binding sites with SV40 and polyoma enhancers. Oncogene. 3:1988;635-646.
    • (1988) Oncogene , vol.3 , pp. 635-646
    • Weisinger, G.1    Remmers, E.F.2    Hearing, P.3    Marcu, K.B.4
  • 47
    • 0342547258 scopus 로고    scopus 로고
    • Ligand-independent activation of the oestrogen receptor by mutation of a conserved tyrosine
    • White R., Sjoberg M., Kalkhoven E., Parker M. G. Ligand-independent activation of the oestrogen receptor by mutation of a conserved tyrosine. EMBO J. 16:1997;1427-1435.
    • (1997) EMBO J. , vol.16 , pp. 1427-1435
    • White, R.1    Sjoberg, M.2    Kalkhoven, E.3    Parker, M.G.4
  • 48
    • 0028876865 scopus 로고
    • The sak1+gene of Schizosaccharomyces pombe encodes an RFX family DNA- binding protein that positively regulates cyclic AMP-dependent protein kinase-mediated exit from the mitotic cell cycle
    • Wu S. Y., McLeod M. The sak1+gene of Schizosaccharomyces pombe encodes an RFX family DNA- binding protein that positively regulates cyclic AMP-dependent protein kinase-mediated exit from the mitotic cell cycle. Mol. Cell Biol. 15:1995;1479-1488.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 1479-1488
    • Wu, S.Y.1    McLeod, M.2
  • 49
    • 0025185783 scopus 로고
    • Binding sites in mammalian genes and viral gene regulatory regions recognized by methylated DNA-binding protein
    • Zhang X. Y., Asiedu C. K., Supakar P. C., Khan R., Ehrlich K. C., Ehrlich M. Binding sites in mammalian genes and viral gene regulatory regions recognized by methylated DNA-binding protein. Nucl. Acids Res. 18:1990;6253-6260.
    • (1990) Nucl. Acids Res. , vol.18 , pp. 6253-6260
    • Zhang, X.Y.1    Asiedu, C.K.2    Supakar, P.C.3    Khan, R.4    Ehrlich, K.C.5    Ehrlich, M.6


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