메뉴 건너뛰기




Volumn 21, Issue 6, 2001, Pages 2057-2069

Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; HISTONE DEACETYLASE; PROTEIN RPD3; PROTEIN SIN3; PROTEIN UME6; REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 0034996711     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.6.2057-2069.2001     Document Type: Article
Times cited : (83)

References (95)
  • 1
    • 0034254857 scopus 로고    scopus 로고
    • NuRD and SIN3 histone deacetylase complexes in development
    • Ahringer, J. 2000. NuRD and SIN3 histone deacetylase complexes in development. Trends Genet. 16:351-356.
    • (2000) Trends Genet. , vol.16 , pp. 351-356
    • Ahringer, J.1
  • 2
    • 0029161996 scopus 로고
    • UME6, a negative regulator of meiosis in Saccharomyces cerevisiae, contains a C-terminal Zn2Cys6 binuclear cluster that binds the URSI DNA sequence in a zinc-dependent manner
    • Anderson, S. F., C. M. Steber, R. E. Esposito, and J. E. Coleman. 1995. UME6, a negative regulator of meiosis in Saccharomyces cerevisiae, contains a C-terminal Zn2Cys6 binuclear cluster that binds the URSI DNA sequence in a zinc-dependent manner. Protein Sci. 4:1832-1843.
    • (1995) Protein Sci. , vol.4 , pp. 1832-1843
    • Anderson, S.F.1    Steber, C.M.2    Esposito, R.E.3    Coleman, J.E.4
  • 3
    • 0032940072 scopus 로고    scopus 로고
    • Historic deacetylases: Transcriptional repression with SINers and NuRDs
    • Ayer, D. E. 1999. Historic deacetylases: transcriptional repression with SINers and NuRDs. Trends Cell Biol. 9:193-198.
    • (1999) Trends Cell Biol. , vol.9 , pp. 193-198
    • Ayer, D.E.1
  • 5
    • 0028905563 scopus 로고
    • Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3
    • Ayer, D. E., Q. A. Lawrence, and R. N. Eisenman. 1995. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell 80:767-776.
    • (1995) Cell , vol.80 , pp. 767-776
    • Ayer, D.E.1    Lawrence, Q.A.2    Eisenman, R.N.3
  • 6
    • 0000884978 scopus 로고
    • Using the two-hybrid system to detect protein-protein interactions
    • D. A. Hartley (ed.). Oxford University Press, Oxford, England
    • Bartel, P. L., C.-T. Chien, R. Sternglanz, and S. Fields. 1993. Using the two-hybrid system to detect protein-protein interactions, p. 153-179. In D. A. Hartley (ed.), Cellular interactions in development: a practical approach. Oxford University Press, Oxford, England.
    • (1993) Cellular Interactions in Development: A Practical Approach , pp. 153-179
    • Bartel, P.L.1    Chien, C.-T.2    Sternglanz, R.3    Fields, S.4
  • 7
    • 0032480015 scopus 로고    scopus 로고
    • The thyroid hormone receptor functions as a ligand-operated developmental switch between proliferation and differentiation of erythroid progenitors
    • Bauer, A., W. Mikulits, G. Lagger, G. Stengl, C. Brosch, and H. Beug. 1998. The thyroid hormone receptor functions as a ligand-operated developmental switch between proliferation and differentiation of erythroid progenitors. EMBO J. 17:4291-4303.
    • (1998) EMBO J. , vol.17 , pp. 4291-4303
    • Bauer, A.1    Mikulits, W.2    Lagger, G.3    Stengl, G.4    Brosch, C.5    Beug, H.6
  • 8
    • 0027407636 scopus 로고
    • Bipartite structure of an early meiotic upstream activation sequence from Saccharomyces cerevisiae
    • Bowdish, K. S., and A. P. Mitchell. 1993. Bipartite structure of an early meiotic upstream activation sequence from Saccharomyces cerevisiae. Mol. Cell. Biol. 13:2172-2181.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2172-2181
    • Bowdish, K.S.1    Mitchell, A.P.2
  • 9
    • 0029006193 scopus 로고
    • Positive control of yeast meiotic genes by the negative regulator UME6
    • Bowdish, K. S., H. E. Yuan, and A. P. Mitchell. 1995. Positive control of yeast meiotic genes by the negative regulator UME6. Mol. Cell. Biol. 15:2955-2961.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2955-2961
    • Bowdish, K.S.1    Yuan, H.E.2    Mitchell, A.P.3
  • 11
    • 0033535840 scopus 로고    scopus 로고
    • GCN5-dependent histone H3 acetylation and RPD3-dependent histone H4 deacetylation have distinct, opposing effects on IME2 transcription, during meiosis and during vegetative growth, in budding yeast
    • Burgess, S. M., M. Ajimura, and N. Kleckner. 1999. GCN5-dependent histone H3 acetylation and RPD3-dependent histone H4 deacetylation have distinct, opposing effects on IME2 transcription, during meiosis and during vegetative growth, in budding yeast. Proc. Natl. Acad. Sci. USA 96:6835-6840.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6835-6840
    • Burgess, S.M.1    Ajimura, M.2    Kleckner, N.3
  • 12
    • 0029929846 scopus 로고    scopus 로고
    • SUMI-1, a dominant suppressor of SIR mutations in Saccharomyces cerevisiae, increases transcriptional silencing at telomeres and HM mating-type loci and decreases chromosome stability
    • Chi, M. H., and D. Shore. 1996. SUMI-1, a dominant suppressor of SIR mutations in Saccharomyces cerevisiae, increases transcriptional silencing at telomeres and HM mating-type loci and decreases chromosome stability. Mol. Cell. Biol. 16:4281-4294.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4281-4294
    • Chi, M.H.1    Shore, D.2
  • 14
    • 0032905924 scopus 로고    scopus 로고
    • c-Myc target genes involved in cell growth, apoptosis, and metabolism
    • Dang, C. V. 1999. c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol. Cell. Biol. 19:1-11.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1-11
    • Dang, C.V.1
  • 15
    • 0032516221 scopus 로고    scopus 로고
    • Histone deacetylase associated with mSin3A mediates repression by the acute promyclocytic leukemia-associated PLZF protein
    • David, G., L. Alland, S. H. Hong, C. W. Wong, R. A. DePinho, and A. Dejean. 1998. Histone deacetylase associated with mSin3A mediates repression by the acute promyclocytic leukemia-associated PLZF protein. Oncogene 16: 2549-2556.
    • (1998) Oncogene , vol.16 , pp. 2549-2556
    • David, G.1    Alland, L.2    Hong, S.H.3    Wong, C.W.4    DePinho, R.A.5    Dejean, A.6
  • 16
    • 0001040367 scopus 로고
    • An algorithm for protein secondary structure prediction based on class prediction
    • Deleage, G., and B. Roux. 1987. An algorithm for protein secondary structure prediction based on class prediction. Protein Eng. 1:289-294.
    • (1987) Protein Eng. , vol.1 , pp. 289-294
    • Deleage, G.1    Roux, B.2
  • 17
    • 0032531688 scopus 로고    scopus 로고
    • The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deracetylase containing complex to mediate transcriptional repression
    • Dhordain, P., R. J. Lin, S. Quief, D. Lantoine, J. Kerckaert, R. M. Evans, and O. Albagli. 1998. The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deracetylase containing complex to mediate transcriptional repression. Nucleic Acids Res. 26:4645-4651.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 4645-4651
    • Dhordain, P.1    Lin, R.J.2    Quief, S.3    Lantoine, D.4    Kerckaert, J.5    Evans, R.M.6    Albagli, O.7
  • 18
    • 0032702675 scopus 로고
    • A 13-amino acid amphipathic alpha-helix is required for the functional interaction between the transcriptional repressor Mad1 and mSin.3A
    • Eilers, A. L., A. N. Billin, J. Liu, and D. E. Aver. 1994. A 13-amino acid amphipathic alpha-helix is required for the functional interaction between the transcriptional repressor Mad1 and mSin.3A. J. Biol. Chem. 274:32750-32756.
    • (1994) J. Biol. Chem. , vol.274 , pp. 32750-32756
    • Eilers, A.L.1    Billin, A.N.2    Liu, J.3    Aver, D.E.4
  • 19
    • 0029043843 scopus 로고
    • The upstream region of the FOX3 gene encoding peroxisomal 3-oxoacyl-coenzyme A thiolase in Saccharomyces cerevisiae contains ABF1- and replication protein A-binding sites that participate in its regulation by glucose repression
    • Einerhand, A. W., W. Kos, W. C. Smart, A. J. Kal, H. F. Tabak, and T. G. Cooper. 1995. The upstream region of the FOX3 gene encoding peroxisomal 3-oxoacyl-coenzyme A thiolase in Saccharomyces cerevisiae contains ABF1- and replication protein A-binding sites that participate in its regulation by glucose repression. Mol. Cell. Biol. 15:3405-3414.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3405-3414
    • Einerhand, A.W.1    Kos, W.2    Smart, W.C.3    Kal, J.4    Tabak, H.F.5    Cooper, T.G.6
  • 20
    • 0034663636 scopus 로고    scopus 로고
    • Combinatorial regulation of phospholipid biosynthetic gene expression by the UME6, SIN3 and RPD3 genes
    • Elkhaimi, M., M. R. Kaadige, D. Kamath, J. C. Jackson, H. Biliran, Jr., and J. M. Lopes. 2000. Combinatorial regulation of phospholipid biosynthetic gene expression by the UME6, SIN3 and RPD3 genes. Nucleic Acids Res. 28: 3160-3167.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 3160-3167
    • Elkhaimi, M.1    Kaadige, M.R.2    Kamath, D.3    Jackson, J.C.4    Biliran H., Jr.5    Lopes, J.M.6
  • 21
    • 0029973652 scopus 로고    scopus 로고
    • Participation of the yeast activator Abf1 in meiosis-specific expression of the IIOP1 gene
    • Gailus-Durner, V., J. Xie, C. Chintamaneni, and A. K. Vershon. 1996. Participation of the yeast activator Abf1 in meiosis-specific expression of the IIOP1 gene. Mol. Cell. Biol. 16:2777-2786.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2777-2786
    • Gailus-Durner, V.1    Xie, J.2    Chintamaneni, C.3    Vershon, A.K.4
  • 22
    • 0028009149 scopus 로고
    • SOPM: A self-optimized method for protein secondary structure prediction
    • Geourjon, C., and G. Deleage. 1994. SOPM: a self-optimized method for protein secondary structure prediction. Protein Eng. 7:157-164.
    • (1994) Protein Eng. , vol.7 , pp. 157-164
    • Geourjon, C.1    Deleage, G.2
  • 23
    • 0029595442 scopus 로고
    • SOPMA: Significant improvements in protein secondary structure prediction by consensus prediction from multiple alignments
    • Geourjon, C., and G. Deleage. 1995. SOPMA: significant improvements in protein secondary structure prediction by consensus prediction from multiple alignments. Comput. Appl. Biosci. 11:681-684.
    • (1995) Comput. Appl. Biosci. , vol.11 , pp. 681-684
    • Geourjon, C.1    Deleage, G.2
  • 24
    • 0023555768 scopus 로고
    • Further developments of protein secondary structure prediction using information theory. New parameters and consideration of residue pairs
    • Gibrat, J. F., J. Garnier, and B. Robson. 1987. Further developments of protein secondary structure prediction using information theory. New parameters and consideration of residue pairs. J. Mol. Biol. 198:425-443.
    • (1987) J. Mol. Biol. , vol.198 , pp. 425-443
    • Gibrat, J.F.1    Garnier, J.2    Robson, B.3
  • 26
    • 0034650893 scopus 로고    scopus 로고
    • The coregulator exchange in transcriptional functions of nuclear receptors
    • Glass, C. K., and M. G. Rosenfeld. 2000. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 14:121-141.
    • (2000) Genes Dev. , vol.14 , pp. 121-141
    • Glass, C.K.1    Rosenfeld, M.G.2
  • 27
    • 0034721670 scopus 로고    scopus 로고
    • The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p
    • Goldmark, J. P., T. G. Fazzio, P. W. Estep, G. M. Church, and T. Tsukiyama. 2000. The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p. Cell 103:423-433.
    • (2000) Cell , vol.103 , pp. 423-433
    • Goldmark, J.P.1    Fazzio, T.G.2    Estep, P.W.3    Church, G.M.4    Tsukiyama, T.5
  • 28
    • 0029656067 scopus 로고    scopus 로고
    • Isolation and analysis of the yeast TEA1 gene, which encodes a zinc cluster Ty enhancer-binding protein
    • Gray, W. M., and J. S. Fassler. 1996. Isolation and analysis of the yeast TEA1 gene, which encodes a zinc cluster Ty enhancer-binding protein. Mol. Cell. Biol. 16:347-358.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 347-358
    • Gray, W.M.1    Fassler, J.S.2
  • 29
    • 0025977037 scopus 로고
    • Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
    • Guan, K. L., and J. E. Dixon. 1991. Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem. 192:262-267.
    • (1991) Anal. Biochem. , vol.192 , pp. 262-267
    • Guan, K.L.1    Dixon, J.E.2
  • 30
    • 0029737603 scopus 로고    scopus 로고
    • Sin3 corepressor function in Myc-induced transcription and transformation
    • Harper, S. E., Y. Qiu, and P. A. Sharp. 1996. Sin3 corepressor function in Myc-induced transcription and transformation. Proc. Natl. Acad. Sci. USA 93:8536-8540.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8536-8540
    • Harper, S.E.1    Qiu, Y.2    Sharp, P.A.3
  • 31
    • 0031244521 scopus 로고    scopus 로고
    • Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs
    • Hassig, C. A., and S. L. Schreiber. 1997. Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs. Curr. Opin. Chem. Biol. 1:300-308.
    • (1997) Curr. Opin. Chem. Biol. , vol.1 , pp. 300-308
    • Hassig, C.A.1    Schreiber, S.L.2
  • 32
    • 0031708269 scopus 로고    scopus 로고
    • NDT80 and the meiotic recombination checkpoint regulate expression of middle sporulation-specific genes in Saccharomyces cerevisiae
    • Hepworth, S. R., H. Friesen, and J. Segall. 1998. NDT80 and the meiotic recombination checkpoint regulate expression of middle sporulation-specific genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 18:5750-5761.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5750-5761
    • Hepworth, S.R.1    Friesen, H.2    Segall, J.3
  • 33
    • 0030457014 scopus 로고    scopus 로고
    • Ubiquitin-dependent protein degradation
    • Hochstrasser, M. 1996. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30:405-439.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 405-439
    • Hochstrasser, M.1
  • 35
    • 0031027008 scopus 로고    scopus 로고
    • Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites
    • Hurlin, P. J., C. Queva, and R. N. Eisenman. 1997. Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites. Genes Dev. 11:44-58.
    • (1997) Genes Dev. , vol.11 , pp. 44-58
    • Hurlin, P.J.1    Queva, C.2    Eisenman, R.N.3
  • 36
    • 0028889811 scopus 로고
    • Mad3 and Mad4: Novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation
    • Hurlin, P. J., C. Queva, P. J. Koskinen, E. Steingrimsson, D. E. Ayer, N. G. Copeland, N. A. Jenkins, and R. N. Eisenman. 1995. Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. EMBO J. 14:5646-5659.
    • (1995) EMBO J. , vol.14 , pp. 5646-5659
    • Hurlin, P.J.1    Queva, C.2    Koskinen, P.J.3    Steingrimsson, E.4    Ayer, D.E.5    Copeland, N.G.6    Jenkins, N.A.7    Eisenman, R.N.8
  • 37
    • 0029968853 scopus 로고    scopus 로고
    • The yeast UME6 gene is required for both negative and positive transcriptional regulation of phospholipid biosynthetic gene expression
    • Jackson, J. C., and J. M. Lopes. 1996. The yeast UME6 gene is required for both negative and positive transcriptional regulation of phospholipid biosynthetic gene expression. Nucleic Acids Res. 24:1322-1329.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 1322-1329
    • Jackson, J.C.1    Lopes, J.M.2
  • 38
    • 0030455820 scopus 로고    scopus 로고
    • Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
    • James, P., J. Halladay, and E. A. Craig. 1996. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144:1425-1436.
    • (1996) Genetics , vol.144 , pp. 1425-1436
    • James, P.1    Halladay, J.2    Craig, E.A.3
  • 39
    • 0032520953 scopus 로고    scopus 로고
    • Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo
    • Kadosh, D., and K. Struhl. 1998. Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo. Genes Dev. 12:797-805.
    • (1998) Genes Dev. , vol.12 , pp. 797-805
    • Kadosh, D.1    Struhl, K.2
  • 40
    • 0343924289 scopus 로고    scopus 로고
    • Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters
    • Kadosh, D., and K. Struhl. 1997. Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters. Cell 89:365-371.
    • (1997) Cell , vol.89 , pp. 365-371
    • Kadosh, D.1    Struhl, K.2
  • 41
    • 0031865050 scopus 로고    scopus 로고
    • Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo
    • Kadosh, D., and K. Struhl. 1998. Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo. Mol. Cell. Biol. 18:5121-5127.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5121-5127
    • Kadosh, D.1    Struhl, K.2
  • 42
    • 0029982704 scopus 로고    scopus 로고
    • SIN3-dependent transcriptional repression by interaction with the Mad1 DNA-binding protein
    • Kasten, M. M., D. E. Ayer, and D. J. Stillman. 1996. SIN3-dependent transcriptional repression by interaction with the Mad1 DNA-binding protein. Mol. Cell. Biol. 16:4215-4221.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4215-4221
    • Kasten, M.M.1    Ayer, D.E.2    Stillman, D.J.3
  • 43
    • 0030877160 scopus 로고    scopus 로고
    • A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators
    • Kasten, M. M., S. Dorland, and D. J. Stillman. 1997. A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators. Mol. Cell. Biol. 17:4852-4858.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4852-4858
    • Kasten, M.M.1    Dorland, S.2    Stillman, D.J.3
  • 44
    • 0030716393 scopus 로고    scopus 로고
    • Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins
    • Kasten, M. M., and D. J. Stillman. 1997. Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins. Mol. Gen. Genet. 256:376-386.
    • (1997) Mol. Gen. Genet. , vol.256 , pp. 376-386
    • Kasten, M.M.1    Stillman, D.J.2
  • 45
    • 0019278382 scopus 로고
    • Recombination and chromosome segregation during the single division meiosis in SPOI2-1 and SPOI3-1 diploids
    • Klapholz, S., and R. E. Esposilo. 1980. Recombination and chromosome segregation during the single division meiosis in SPOI2-1 and SPOI3-1 diploids. Genetics 96:589-611.
    • (1980) Genetics , vol.96 , pp. 589-611
    • Klapholz, S.1    Esposilo, R.E.2
  • 46
    • 0034654011 scopus 로고    scopus 로고
    • Acelylation: A regulatory modification to rival phosphorylation?
    • Kouzarides, T. 2000. Acelylation: a regulatory modification to rival phosphorylation? EMBO J. 19:1176-1179.
    • (2000) EMBO J. , vol.19 , pp. 1176-1179
    • Kouzarides, T.1
  • 47
    • 0030710569 scopus 로고    scopus 로고
    • Transcriptional control of the yeast acetyl-CoA synthelase gene, ACS1, by the positive regulators CAT8 and ADR1 and the pleiolropic repressor UME6
    • Kratzer, S., and H. J. Schuller. 1997. Transcriptional control of the yeast acetyl-CoA synthelase gene, ACS1, by the positive regulators CAT8 and ADR1 and the pleiolropic repressor UME6. Mol. Microbiol. 26:631-641.
    • (1997) Mol. Microbiol. , vol.26 , pp. 631-641
    • Kratzer, S.1    Schuller, H.J.2
  • 48
    • 0002077797 scopus 로고    scopus 로고
    • Meiosis and sporulation in Saccharomyces cerevisiae
    • J. R. Pringle, J. R. Broach, and E. W. Jones (ed.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Kupiec, M., B. Byers, R. E. Esposito, and A. P. Mitchell. 1997. Meiosis and sporulation in Saccharomyces cerevisiae, p. 889-1036. In J. R. Pringle, J. R. Broach, and E. W. Jones (ed.), The molecular and cellular biology of the yeast Saccharomyces, vol. 3. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (1997) The Molecular and Cellular Biology of the Yeast Saccharomyces , vol.3 , pp. 889-1036
    • Kupiec, M.1    Byers, B.2    Esposito, R.E.3    Mitchell, A.P.4
  • 50
    • 0031058930 scopus 로고    scopus 로고
    • Pheromone signalling and polarized morphogenesis in yeast
    • Leberer, E., D. Y. Thomas, and M. Whiteway. 1997. Pheromone signalling and polarized morphogenesis in yeast. Curr. Opin. Genet. Dev. 7:59-66.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 59-66
    • Leberer, E.1    Thomas, D.Y.2    Whiteway, M.3
  • 51
    • 0028018892 scopus 로고
    • Detection of protein-protein interactions using different vectors in the two-hybrid system
    • Legrain, P., M. C. Dukhelar, and C. Transy. 1994. Detection of protein-protein interactions using different vectors in the two-hybrid system. Nucleic Acids Res. 22:3241-3242.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 3241-3242
    • Legrain, P.1    Dukhelar, M.C.2    Transy, C.3
  • 52
    • 0023050277 scopus 로고
    • An algorithm for secondary structure determination in proteins based on sequence similarity
    • Levin, J. M., B. Robson, and J. Garnier. 1986. An algorithm for secondary structure determination in proteins based on sequence similarity. FEBS Lett. 205:303-308.
    • (1986) FEBS Lett. , vol.205 , pp. 303-308
    • Levin, J.M.1    Robson, B.2    Garnier, J.3
  • 53
    • 0030771328 scopus 로고    scopus 로고
    • A conformational switch in nuclear hormone receptors is involved in coupling hormone binding to corepressor release
    • Lin, B. C., S. H. Hong, S. Krig, S. M. Yoh, and M. L. Privalsky. 1997. A conformational switch in nuclear hormone receptors is involved in coupling hormone binding to corepressor release. Mol. Cell. Biol. 17:6131-6138.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6131-6138
    • Lin, B.C.1    Hong, S.H.2    Krig, S.3    Yoh, S.M.4    Privalsky, M.L.5
  • 54
    • 0032949304 scopus 로고    scopus 로고
    • Molecular genetics of acute promyelocytic leukemia
    • Lin, R. J., D. A. Egan, and R. M. Evans. 1999. Molecular genetics of acute promyelocytic leukemia. Trends Genet. 15:179-184.
    • (1999) Trends Genet. , vol.15 , pp. 179-184
    • Lin, R.J.1    Egan, D.A.2    Evans, R.M.3
  • 55
    • 0030657650 scopus 로고    scopus 로고
    • Interaction of yeast repressor-activator protein Ume6p with glycogen synthase kinase 3 homolog Rim11p
    • Malathi, K., Y. Xiao, and A. P. Mitchell. 1997. Interaction of yeast repressor-activator protein Ume6p with glycogen synthase kinase 3 homolog Rim11p. Mol. Cell. Biol. 17:7230-7236.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 7230-7236
    • Malathi, K.1    Xiao, Y.2    Mitchell, A.P.3
  • 56
    • 0028344798 scopus 로고
    • IMEI gene encodes a transcription factor which is required to induce meiosis in Saccharomyces cerevisiae
    • Mandel, S., K. Robzyk, and Y. Kassir. 1994. IMEI gene encodes a transcription factor which is required to induce meiosis in Saccharomyces cerevisiae. Dev. Genet. 15:139-147.
    • (1994) Dev. Genet. , vol.15 , pp. 139-147
    • Mandel, S.1    Robzyk, K.2    Kassir, Y.3
  • 58
    • 0033970431 scopus 로고    scopus 로고
    • The essential cofactor TRRAP recruits the historic acetyltransferase hGCNS to c-Myc
    • McMahon, S. B., M. A. Wood, and M. D. Cole. 2000. The essential cofactor TRRAP recruits the historic acetyltransferase hGCNS to c-Myc. Mol. Cell. Biol. 20:556-562.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 556-562
    • McMahon, S.B.1    Wood, M.A.2    Cole, M.D.3
  • 60
    • 0034127687 scopus 로고    scopus 로고
    • In Saccharomyces cerevisiae, expression of arginine catabolic genes CAR1 and CAR2 in response to exogenous nitrogen availability is mediated by the Ume6 (CargRI)-Sin3 (CargRII)-Rpd3 (CargRIII) complex
    • Messenguy, F., F. Vierendeels, B. Scherens, and E. Dubois. 2000. In Saccharomyces cerevisiae, expression of arginine catabolic genes CAR1 and CAR2 in response to exogenous nitrogen availability is mediated by the Ume6 (CargRI)-Sin3 (CargRII)-Rpd3 (CargRIII) complex. J. Bacteriol. 182:3158-3164.
    • (2000) J. Bacteriol. , vol.182 , pp. 3158-3164
    • Messenguy, F.1    Vierendeels, F.2    Scherens, B.3    Dubois, E.4
  • 61
    • 0028194848 scopus 로고
    • Control of meiotic gene expression in Saccharomyces cerevisiae
    • Mitchell, A. P. 1994. Control of meiotic gene expression in Saccharomyces cerevisiae. Microbiol. Rev. 58:56-70.
    • (1994) Microbiol. Rev. , vol.58 , pp. 56-70
    • Mitchell, A.P.1
  • 62
    • 0027182508 scopus 로고
    • Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeast
    • Mitchell, D. A., T. K. Marshall, and R. J. Deschenes. 1993. Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeast. Yeast 9:715-722.
    • (1993) Yeast , vol.9 , pp. 715-722
    • Mitchell, D.A.1    Marshall, T.K.2    Deschenes, R.J.3
  • 64
    • 0025979877 scopus 로고
    • Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast
    • Rothstein, R. 1991. Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol. 194:281-301.
    • (1991) Methods Enzymol. , vol.194 , pp. 281-301
    • Rothstein, R.1
  • 65
    • 0029990949 scopus 로고    scopus 로고
    • Induction of meiosis in Saccharomyces cerevisiae depends on conversion of the transcriptional represssor Ume6 to a positive regulator by its regulated association with the transcriplional activator Ime1
    • Rubin-Bejerano, I., S. Mandel, K. Robzyk, and Y. Kassir. 1996. Induction of meiosis in Saccharomyces cerevisiae depends on conversion of the transcriptional represssor Ume6 to a positive regulator by its regulated association with the transcriplional activator Ime1. Mol. Cell. Biol. 16:2518-2526.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2518-2526
    • Rubin-Bejerano, I.1    Mandel, S.2    Robzyk, K.3    Kassir, Y.4
  • 66
    • 0032560117 scopus 로고    scopus 로고
    • Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3
    • Rundlett, S. E., A. A. Carmen, N. Suka, B. M. Turner, and M. Grunstein. 1998. Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3. Nature 392:831-835.
    • (1998) Nature , vol.392 , pp. 831-835
    • Rundlett, S.E.1    Carmen, A.A.2    Suka, N.3    Turner, B.M.4    Grunstein, M.5
  • 68
    • 0028940364 scopus 로고
    • An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3
    • Schreiber-Agus, N., L. Chin, K. Chen, R. Torres, G. Rao, P. Guida, A. I. Skoultchi, and R. A. DePinho. 1995. An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3. Cell 80:777-786.
    • (1995) Cell , vol.80 , pp. 777-786
    • Schreiber-Agus, N.1    Chin, L.2    Chen, K.3    Torres, R.4    Rao, G.5    Guida, P.6    Skoultchi, A.I.7    DePinho, R.A.8
  • 69
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 70
    • 0029074187 scopus 로고
    • SIN3 works through two different promoter elements Io regulate INO1 gene expression in yeast
    • Slekar, K. H., and S. A. Henry. 1995. SIN3 works through two different promoter elements Io regulate INO1 gene expression in yeast. Nucleic Acids Res. 23:1964-1969.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1964-1969
    • Slekar, K.H.1    Henry, S.A.2
  • 71
    • 0029831111 scopus 로고    scopus 로고
    • Combinatorial regulation of the Saccharomyces cerevisiae CAR1 (arginase) promoter in response to multiple environmental signals
    • Smart, W. C., J. A. Coffman, and T. G. Cooper. 1996. Combinatorial regulation of the Saccharomyces cerevisiae CAR1 (arginase) promoter in response to multiple environmental signals. Mol. Cell. Biol. 16:5876-5887.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5876-5887
    • Smart, W.C.1    Coffman, J.A.2    Cooper, T.G.3
  • 72
    • 0027516052 scopus 로고
    • Genetic evidence for transcriptional activation by the yeast IME1 gene product
    • Smith, H. E., S. E. Driscoll, R. A. Sia, H. E. Yuan, and A. P. Mitchell. 1993. Genetic evidence for transcriptional activation by the yeast IME1 gene product. Genetics 133:775-784.
    • (1993) Genetics , vol.133 , pp. 775-784
    • Smith, H.E.1    Driscoll, S.E.2    Sia, R.A.3    Yuan, H.E.4    Mitchell, A.P.5
  • 73
    • 0025243401 scopus 로고
    • Role of IME1 expression in regulation of meiosis in Saccharomyces cerevisiae
    • Smith, H. E., S. S. Su, L. Neigeborn, S. E. Driscoll, and A. P. Mitchell. 1990. Role of IME1 expression in regulation of meiosis in Saccharomyces cerevisiae. Mol. Cell. Biol. 10:6103-6113.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6103-6113
    • Smith, H.E.1    Su, S.S.2    Neigeborn, L.3    Driscoll, S.E.4    Mitchell, A.P.5
  • 74
    • 0029557246 scopus 로고
    • UME6 is a central component of a developmental regulatory switch controlling meiosis-specific gene expression
    • Steber, C. M., and R. E. Esposito. 1995. UME6 is a central component of a developmental regulatory switch controlling meiosis-specific gene expression. Proc. Natl. Acad. Sci. USA 92:12490-12494.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12490-12494
    • Steber, C.M.1    Esposito, R.E.2
  • 75
    • 0023666071 scopus 로고
    • Activation of the yeast HO gene by release from multiple negative controls
    • Sternberg, P. W., M. J. Stern, I. Clark, and I. Herskowitz. 1987. Activation of the yeast HO gene by release from multiple negative controls. Cell 48:567-577.
    • (1987) Cell , vol.48 , pp. 567-577
    • Sternberg, P.W.1    Stern, M.J.2    Clark, I.3    Herskowitz, I.4
  • 76
    • 0024834986 scopus 로고
    • Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast
    • Strich, R., M. R. Slater, and R. E. Esposito. 1989. Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast. Proc. Natl. Acad. Sci. USA 86:10018-10022.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 10018-10022
    • Strich, R.1    Slater, M.R.2    Esposito, R.E.3
  • 79
    • 0030868390 scopus 로고    scopus 로고
    • Role of UME6 in transcriptional regulation of a DNA repair gene in Saccharomyces cerevisiae
    • Sweet, D. H., Y. K. Jang, and G. B. Sancar. 1997. Role of UME6 in transcriptional regulation of a DNA repair gene in Saccharomyces cerevisiae. Mol. Cell. Biol. 17:6223-6235.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6223-6235
    • Sweet, D.H.1    Jang, Y.K.2    Sancar, G.B.3
  • 80
    • 0028847223 scopus 로고
    • A bipartite operator interacts with a heat shock element to mediate early meiotic induction of Saccharomyces cerevisiae HSP82
    • Szent-Gyorgyi, C. 1995. A bipartite operator interacts with a heat shock element to mediate early meiotic induction of Saccharomyces cerevisiae HSP82. Mol. Cell. Biol. 15:6754-6769.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6754-6769
    • Szent-Gyorgyi, C.1
  • 81
    • 0024977417 scopus 로고
    • Elevated recombination rates in transcriptionally active DNA
    • Thomas, B. J., and R. Rothstein. 1989. Elevated recombination rates in transcriptionally active DNA. Cell 56:619-630.
    • (1989) Cell , vol.56 , pp. 619-630
    • Thomas, B.J.1    Rothstein, R.2
  • 82
    • 0031835267 scopus 로고    scopus 로고
    • Co-activators and co-repressors in the integration of transcriptional responses
    • Torchia, J., C. Glass, and M. G. Rosenfeld. 1998. Co-activators and co-repressors in the integration of transcriptional responses. Curr. Opin. Cell Biol. 10:373-383.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 373-383
    • Torchia, J.1    Glass, C.2    Rosenfeld, M.G.3
  • 83
    • 0030465738 scopus 로고    scopus 로고
    • Evidence that the transcriptional regulators SIN3 and RPD3, and a novel gene (SDS3) with similar functions, are involved in transcriptional silencing in S. cerevisiae
    • Vannier, D., D. Balderes, and D. Shore. 1996. Evidence that the transcriptional regulators SIN3 and RPD3, and a novel gene (SDS3) with similar functions, are involved in transcriptional silencing in S. cerevisiae. Genetics 144:1343-1353.
    • (1996) Genetics , vol.144 , pp. 1343-1353
    • Vannier, D.1    Balderes, D.2    Shore, D.3
  • 84
    • 0034020067 scopus 로고    scopus 로고
    • Transcriptional regulation of meiosis in yeast
    • Vershon, A. K., and M. Pierce. 2000. Transcriptional regulation of meiosis in yeast. Curr. Opin. Cell Biol. 12:334-339.
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 334-339
    • Vershon, A.K.1    Pierce, M.2
  • 85
    • 0026060619 scopus 로고
    • RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae
    • Vidal, M., and R. F. Gaber. 1991. RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:6317-6327.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 6317-6327
    • Vidal, M.1    Gaber, R.F.2
  • 86
    • 0026046959 scopus 로고
    • RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes
    • Vidal, M., R. Strich, R. E. Esposito, and R. F. Gaber. 1991. RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes. Mol. Cell. Biol. 11:6306-6316.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 6306-6316
    • Vidal, M.1    Strich, R.2    Esposito, R.E.3    Gaber, R.F.4
  • 87
    • 0029871347 scopus 로고    scopus 로고
    • PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae
    • Wach, A. 1996. PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae. Yeast 12:259-265.
    • (1996) Yeast , vol.12 , pp. 259-265
    • Wach, A.1
  • 88
    • 0025096058 scopus 로고
    • The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs
    • Wang, H., I. Clark, P. R. Nicholson, I. Herskowitz, and D. J. Stillman. 1990. The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs. Mol. Cell. Biol. 10:5927-5936.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5927-5936
    • Wang, H.1    Clark, I.2    Nicholson, P.R.3    Herskowitz, I.4    Stillman, D.J.5
  • 89
    • 0025218814 scopus 로고
    • Identification of a Saccharomyces cerevisiae DNA-binding protein involved in transcriptional regulation
    • Wang, H., P. R. Nicholson, and D. J. Stillman. 1990. Identification of a Saccharomyces cerevisiae DNA-binding protein involved in transcriptional regulation. Mol. Cell. Biol. 10:1743-1753.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 1743-1753
    • Wang, H.1    Nicholson, P.R.2    Stillman, D.J.3
  • 90
    • 0027479075 scopus 로고
    • Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein
    • Wang, H., and D. J. Stillman, 1993. Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein. Mol. Cell. Biol. 13:1805-1814.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1805-1814
    • Wang, H.1    Stillman, D.J.2
  • 92
    • 0030922545 scopus 로고    scopus 로고
    • Transcriptional control. Sinful repression
    • Wolffe, A. P. 1997. Transcriptional control. Sinful repression. Nature 387:16-17.
    • (1997) Nature , vol.387 , pp. 16-17
    • Wolffe, A.P.1
  • 93
    • 0033913190 scopus 로고    scopus 로고
    • Shared roles of yeast glycogen synthase kinase 3 family members in nitrogen-responsive phosphorylation of meiotic regulator Ume6p
    • Xiao, Y., and A. P. Mitchell. 2000. Shared roles of yeast glycogen synthase kinase 3 family members in nitrogen-responsive phosphorylation of meiotic regulator Ume6p. Mol. Cell. Biol. 20:5447-5453.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5447-5453
    • Xiao, Y.1    Mitchell, A.P.2
  • 94
    • 0033570901 scopus 로고    scopus 로고
    • Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae
    • Xie, J., M. Pierce, V. Gailus-Durner, M. Wagner, E. Winter, and A. K. Vershon. 1999. Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae. EMBO J. 18:6448-6454.
    • (1999) EMBO J. , vol.18 , pp. 6448-6454
    • Xie, J.1    Pierce, M.2    Gailus-Durner, V.3    Wagner, M.4    Winter, E.5    Vershon, A.K.6
  • 95
    • 0030916729 scopus 로고    scopus 로고
    • Histone deacetylases and SAPI8, a novel polypeptide, are components of a human Sin3 complex
    • Zhang, Y., R. Iratni, H. Erdjument-Bromage, P. Tempst, and D. Reinberg. 1997. Histone deacetylases and SAPI8, a novel polypeptide, are components of a human Sin3 complex. Cell 89:357-364.
    • (1997) Cell , vol.89 , pp. 357-364
    • Zhang, Y.1    Iratni, R.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.